Early leukemia diagnostics	  	  Startup Village 14-05-2013Andrey Senyut senyut@immunoslide.com
LeukemiaLeading cause of death among children under 15250 000 deaths per year350 000 new casesper year
The disease is detected TOO LATE	  Common methods of leukemia diagnostics areNOT SENSITIVE ENOUGHONLY 4% are diagnosed at ...
ImmunoSlide Affordable priceHigh accuracy
ImmunoslideAbnormal blood cells appear in a person’s blood stream when he has leukemia.Pathological cells differ from norm...
Immunoslide(disposable)Device for an automatedanalysis of immunoslide+	  Product73% margin200 000 rubles15% margin300 rubl...
ImmunoSlide	  Flow	  cytometry	  	  Immunocitochemistry	  Blood	  smear	  Morphological	  analysis	  (Cell	  outlook	  ana...
Overall market volume - 0.5 bln $Russian marketPRIVATE MARKETGOVERNMENTAL MARKETrevenue in 5 years – 30 mln $Required inve...
Fazly	  Ataullakhanov,	  Member	  of	  the	  Na?onal	  Biochemical	  Society	  of	  Russia	  (1975)	  and	  Member	  of	  ...
– winner of the grant START 2012
We are Skolkovo residents
Thank you for your attention!mail@immunoslide.com	  Q&A?	  
Sensi?ve	  Y Y Y YAn6gen	  Immobilized	  an6body	  Blood	  cell	  Immunoslide	  gives	  10	  TIMES	  HIGHER	  CHANCE	  of	...
0	  20,000	  40,000	  60,000	  80,000	  100,000	  120,000	  140,000	  1	   2	   3	   4	   5	   6	   7	   8	   9	  -­‐40000...
Ready by 80%PrototypeNo manual labor required
D. Rogachev’s children’s hematological centerGovernmental clinical and diagnostic laboratories	  Private clinical and diag...
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26-28 MAY, 2013 - FIRST ANNUAL YOUTH ENTREPRENEURSHIP AND INNOVATORS CONFERENCE IN RUSSIA. STARTUP VILLAGE - one of the most ambitious start-up conferences in Russia, organized by Skolkovo in cooperation with partners. The conference is the first this year and will be held annually.

ImSlide is the first conference day's pitch session participant in the Life Science pavillion.

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  1. 1.  Early leukemia diagnostics    Startup Village 14-05-2013Andrey Senyut senyut@immunoslide.com
  2. 2. LeukemiaLeading cause of death among children under 15250 000 deaths per year350 000 new casesper year
  3. 3. The disease is detected TOO LATE  Common methods of leukemia diagnostics areNOT SENSITIVE ENOUGHONLY 4% are diagnosed at the stage ofpreventive inspectionProblem
  4. 4. ImmunoSlide Affordable priceHigh accuracy
  5. 5. ImmunoslideAbnormal blood cells appear in a person’s blood stream when he has leukemia.Pathological cells differ from normal ones by:External appearance(morphology)Antigens on their surface(immunophenotype)There must be no cells with“CD11C-”   antigen (special protein)on their surface when a person ishealthy.  Common methods of leukemia diagnostics (blood smear) don’t deliver the dataabout cell’s surface antigens.Immunoslide allows doctor to receive data both on the externalappearance of blood cells and on the surface antigens of blood cells.EXAMPLEPathological cellsEXAMPLE
  6. 6. Immunoslide(disposable)Device for an automatedanalysis of immunoslide+  Product73% margin200 000 rubles15% margin300 rubles per test
  7. 7. ImmunoSlide  Flow  cytometry    Immunocitochemistry  Blood  smear  Morphological  analysis  (Cell  outlook  analysis)  ++   -­‐-­‐   -­‐   +  Immunophenotyping  (Cell  surface  an?gens  analysis)  +   ++   +   -­‐-­‐  Cost  of  one  test      6$   10  –  30$   20  –  40$   3$  Cost  of  equipment   7  000$   100  000$   -­‐   -­‐  Dura?on  of  analysis   1,5  hour   0,5  hour   3  hours   0,5  hour  Simplicity  of  exploita?on   +   -­‐-­‐   -­‐-­‐   +  Competitors
  8. 8. Overall market volume - 0.5 bln $Russian marketPRIVATE MARKETGOVERNMENTAL MARKETrevenue in 5 years – 30 mln $Required investments 2 mln $
  9. 9. Fazly  Ataullakhanov,  Member  of  the  Na?onal  Biochemical  Society  of  Russia  (1975)  and  Member  of  the  Biophysical  Society  of  USA  (1997),  Editorial  board  of  “Biologicheskie  Membrany”  (1989),  Member  of  the  Science   Council   of   Ins?tute   for   Chemical   Biophysics   (1997),   Editorial  Board  of  Open  Journal  of  Structural  Biology,  Bentham  Pub,  USA  and  Journal  of  Biophysics  (open  access)  (2007),  Member  of  Academy  of  the  Natural  Sciences.      Igor   Pivovarov,   Member   of   execu?ve   boards   of   several   innova?ve  companies.  CEO  of  LLC  “HemaCore”,  the  joint  project  with  RUSNANO  venture  fund.  HemaCore  develops  the  unique  medical  equipment  for  precise   diagnos?cs   of   coagula?on   disorders.   Igor   has   5   year   work  experience  in  biotech  as  CTO,  CMO,  CEO.  Raised  about  660  mln.  rubles  of  investments.    Mentors
  10. 10. – winner of the grant START 2012
  11. 11. We are Skolkovo residents
  12. 12. Thank you for your attention!mail@immunoslide.com  Q&A?  
  13. 13. Sensi?ve  Y Y Y YAn6gen  Immobilized  an6body  Blood  cell  Immunoslide  gives  10  TIMES  HIGHER  CHANCE  of  finding  leukemia  at  it’s  early  stage    Devise  for  early  leukemia  diagnos?cs.  Affordable  CD  4   CD  4   CD  8   CD  8  Immunoslide
  14. 14. 0  20,000  40,000  60,000  80,000  100,000  120,000  140,000  1   2   3   4   5   6   7   8   9  -­‐40000  -­‐20000  0  20000  40000  60000  80000  100000  120000  140000  1   2   3   4   5   6   7   8   9  -­‐20000  0  20000  40000  60000  80000  100000  120000  140000  160000  1   2   3   4   5   6   7   8   9  Thousands of rubleshalf yearNPV = 41 mln rubles, r = 40%IRR = 69%PBP = 3.8 yearsRequired investments54 mln rubCFCF without bringing ininvestmnetsEBITDAFinancial forecastThousands of rublesThousands of rubleshalf yearhalf year
  15. 15. Ready by 80%PrototypeNo manual labor required
  16. 16. D. Rogachev’s children’s hematological centerGovernmental clinical and diagnostic laboratories  Private clinical and diagnostic laboratoriesMorozov children’s hospitalPartnersHematological science center

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