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Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
Cholesterol Management
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Cholesterol Management

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Cholesterol Management, presented by Christian Zellner MD, Cardiology, Springfield Clinic. …

Cholesterol Management, presented by Christian Zellner MD, Cardiology, Springfield Clinic.

Originally presented at Springfield Clinic Me 1st Women's Health Event, May 2010 - All information and images provided by presenter.

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  • 1. Love your Heart: Cholesterol Management Christian Zellner, MD Department of Cardiology
  • 2. Love Your Heart <ul><li>Why should you care? </li></ul><ul><li>At what age do I need to start? </li></ul><ul><li>What is cholesterol ? </li></ul><ul><li>How can I lower my cholesterol? </li></ul>
  • 3. Why Should You Care?
  • 4. Heart Disease in Women <ul><li>Leading cause of death </li></ul><ul><li>Women are 4 times more likely to die from heart disease than men </li></ul><ul><li>Prevention can substantially reduce risk </li></ul><ul><li>Diet is key </li></ul><ul><li>Consider drug side-effects </li></ul>
  • 5. When Do I Need to Start? <ul><li>Get started in your 20’s </li></ul><ul><li>Step it up in your 30’s </li></ul><ul><li>Get serious in your 40’s </li></ul><ul><li>Add medication when needed </li></ul>
  • 6. Cholesterol <ul><li>Basic building block of Life </li></ul><ul><li>Our bodies contain 35 g of cholesterol </li></ul><ul><li>1,000 mg synthesized each day </li></ul><ul><li>About 300 mg taken up each day </li></ul>
  • 7. Cholesterol <ul><li>Entirely derived from animal sources </li></ul><ul><li>Plants contain sterols </li></ul>
  • 8. Cholesterol <ul><li>25% of cholesterol is made in the liver </li></ul><ul><li>Recycling via bile and GI tract </li></ul>
  • 9. Cholesterol <ul><li>Konrad Bloch and Feodor Lynen shared the Nobel Prize in 1964 </li></ul><ul><li>Reduction in intake may increase internal production </li></ul>
  • 10. Cholesterol <ul><li>Passive uptake of cholesterol from diet in the GI tract </li></ul><ul><li>Sterols actively returned into gut </li></ul>
  • 11. Cholesterol <ul><li>What Makes Up Cholesterol? </li></ul><ul><li>Cholesterol </li></ul><ul><li>Triglycerides </li></ul>
  • 12. Cholesterol <ul><li>What Makes Up Cholesterol? </li></ul><ul><li>HDL </li></ul><ul><li>LDL </li></ul><ul><li>VLDL </li></ul>
  • 13. Cholesterol <ul><li>Gender-related Lipid Topics </li></ul><ul><li>Women have higher HDL </li></ul><ul><li>Estrogen therapy can cause elevated triglycerides </li></ul><ul><li>Risk of statins during pregnancy </li></ul>
  • 14. Cholesterol <ul><li>What Affects LDL Cholesterol? </li></ul><ul><li>Diet: Saturated Fats </li></ul><ul><li>Obesity </li></ul><ul><li>Thyroid Disease </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul>
  • 15. Cholesterol <ul><li>What Affects HDL Cholesterol? </li></ul><ul><li>Obesity </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul><ul><li>Smoking </li></ul><ul><li>Certain drugs </li></ul><ul><li>Diabetes </li></ul>
  • 16. Cholesterol <ul><li>What Affects Triglycerides? </li></ul><ul><li>Obesity </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul><ul><li>High Carb Diet </li></ul><ul><li>Certain drugs </li></ul><ul><li>Diabetes </li></ul>
  • 17. What You Can Do: <ul><li>How Can I Lower My Cholesterol? </li></ul>
  • 18. How Can I Lower My Cholesterol? <ul><li>Cut Back on Saturated Fats </li></ul>
  • 19. How Can I Lower My Cholesterol?
  • 20. How Can I Lower My Cholesterol? <ul><li>Add Phytosterols to Your Diet </li></ul><ul><li>Sesame and Olive Oil </li></ul><ul><li>Nuts (Almonds) </li></ul><ul><li>Wheat Bran </li></ul><ul><li>(Take Control, Benecol) </li></ul><ul><li>Synergy when taken with statins </li></ul>
  • 21. How Can I Lower My Cholesterol?
  • 22. Cholesterol Drugs: Statins <ul><li>Dr. Michael S. Brown and Dr. Joseph L. Goldstein received Nobel Price in1985 for discovery of HMG-CoA reductase </li></ul><ul><li>Inhibits cholesterol synthesis and increases LDL cholesterol uptake in liver </li></ul>
  • 23. Cholesterol Drugs: Statins <ul><li>Lipitor </li></ul><ul><li>Crestor </li></ul><ul><li>Simvastatin </li></ul><ul><li>Pravastatin </li></ul><ul><li>Lovastatin </li></ul>
  • 24. Cholesterol Drugs: Statins <ul><li>1,200mg twice daily </li></ul>
  • 25. Cholesterol Drugs: Fish Oil <ul><li>1000mg to 3000mg DHA and EPA </li></ul>
  • 26. Cholesterol Drugs: Krill Oil <ul><li>2000mg – 3000mg Krill Oil </li></ul>
  • 27. Love Your Heart <ul><li>Eat Right </li></ul><ul><li>Exercise </li></ul><ul><li>Don’t Smoke </li></ul><ul><li>Know your Family History </li></ul><ul><li>Keep Regular Check-ups with your Doctor </li></ul>
  • 28. Love Your Heart

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