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Technical Note

   Arthroscopic Grafting of Greater Tuberosity Cyst and Rotator
                           Cuff Repair

                                Vivek Agrawal, M.D., and Matthew Stinson, P.A.-C.



              Abstract: Cysts of the greater tuberosity can be a normal finding independent of age and concurrent
              rotator cuff tear. The presence of a large greater tuberosity cyst can present a challenge at the time
              of rotator cuff repair. We present a 1-step arthroscopic technique to address these defects at the time
              of rotator cuff repair using a synthetic graft (OsteoBiologics, San Antonio, TX) originally designed
              to address osteoarticular defects. With the viewing portal established laterally, a portal allowing
              perpendicular access to the cyst is established. The cyst is thoroughly debrided, and a drill sleeve is
              then introduced perpendicular to the surrounding bone, serving as a guide for the matching drill to
              create a circular socket. A correspondingly sized TruFit BGS cylindrical implant (OsteoBiologics) is
              then implanted by use of the included instrumentation. The scaffold is placed flush with the
              surrounding bone. Because our arthroscopic rotator cuff protocol uses a tension-band technique with
              placement of suture anchors distal and lateral to the rotator cuff footprint, we are subsequently able
              to proceed with routine rotator cuff repair. Key Words: Rotator cuff repair—Bone graft—Surgical
              technique—Humeral cyst, shoulder surgery




I  t is unclear whether cysts within the vicinity of
   the rotator cuff insertion on the greater tuberosity
are developmental, are correlated with age-related
                                                                      time of rotator cuff repair. We present a 1-step arthro-
                                                                      scopic technique to address these defects at the time
                                                                      of rotator cuff repair using porous, resorbable
changes, or are specific to rotator cuff pathology.1-4 A              scaffolds composed of polylactide– co-glycolide
radiographic study of patients with symptomatic and                   copolymer, providing structure and calcium sulfate
surgically documented rotator cuff tears has shown a                  and promoting bone ingrowth (TruFit BGS Plug;
positive correlation with greater tuberosity cysts.5 Ex-              OsteoBiologics, San Antonio, TX).
perimental work has also cited bone loss as a possible
factor in poor healing of rotator cuff repairs.6
  The presence of cysts can present a dilemma at the                        TECHNIQUE AND CASE REPORT
                                                                         A 57-year-old woman slipped and fell onto her
                                                                      outstretched dominant arm, injuring her shoulder. Be-
  From The Shoulder Center, St. Vincent Hospital, Indianapolis,       cause pain and weakness persisted despite conserva-
Indiana, U.S.A.                                                       tive management, she was referred to our shoulder
  The authors report no conflict of interest.
  Address correspondence and reprint requests to Vivek Agrawal,       clinic. A thorough radiographic and clinical examina-
M.D., The Shoulder Center, 10801 North Michigan Rd, #100,             tion revealed the presence of both a rotator cuff tear
Zionsville, IN 46077, U.S.A. E-mail: DrAgrawal@TheShoulder            and a significant greater tuberosity subcortical cyst
Center.com
  © 2007 by the Arthroscopy Association of North America              (Fig 1A). After a thorough review of the risks, bene-
  Cite this article as: Agrawal V, Stinson M. Arthroscopic grafting   fits, and options regarding treatment, along with our
of greater tuberosity cyst and rotator cuff repair. Arthroscopy       recommendations, the patient was eager to proceed
2007;23:904.e1-904.e3 [doi:10.1016/j.arthro.2006.10.026].
  0749-8063/07/2308-6387$32.00/0                                      with arthroscopic treatment. We routinely use a semi–
  doi:10.1016/j.arthro.2006.10.026                                    lateral decubitus position for arthroscopic shoulder


Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 23, No 8 (August), 2007: pp 904.e1-904.e3             904.e1
904.e2                                         V. AGRAWAL AND M. STINSON




FIGURE 1. (A) Preoperative magnetic resonance scan, showing greater tuberosity cyst (arrow) and rotator cuff tear (asterisk). (B) Magnetic
resonance scan at 6 months after surgery, showing healed tuberosity cyst (asterisk) and rotator cuff, as well as placement of anchors distal
and lateral to rotator cuff footprint (arrow).



procedures. For arthroscopic rotator cuff repair, the                    scopic shaver. A drill sleeve, matching the size of the
viewing portal is placed laterally, allowing working                     defect, was then inserted perpendicular to the sur-
portals to be placed circumferentially and providing                     rounding greater tuberosity, serving as a guide for the
an orthogonal view of the tuberosity and rotator cuff                    matching drill to create a circular socket. A corre-
tear. After thorough bursectomy and debridement of                       spondingly sized TruFit BGS cylindrical implant (Os-
devitalized tissue were performed, allowing a clear                      teoBiologics) was then implanted by use of the
view of the size and pattern of the patient’s rotator                    included instrumentation. The scaffold was placed
cuff tear, the humeral cyst was localized and probed.                    flush with the surrounding bone (Fig 2A). Because our
A portal adjacent to the lateral border of the acromion                  arthroscopic rotator cuff repair protocol uses a tension-
allowing perpendicular access to the cyst via spinal                     band technique with placement of suture anchors distal
needle localization was established. The cyst was                        and lateral to the rotator cuff footprint, we were able to
thoroughly debrided to bleeding bone with an arthro-                     proceed with routine rotator cuff repair (Fig 2B).




  FIGURE 2. (A) Prepared and grafted defect at greater tuberosity. (B) Placement of anchors distal and lateral to rotator cuff footprint.
GREATER TUBEROSITY CYST                                                       904.e3


  Postoperatively, the patient was started on our stan-        well as a humeral osteochondral defect). Situations
dard arthroscopic rotator cuff repair protocol. Mag-           requiring the bone graft to provide immediate struc-
netic resonance imaging performed 6 months postop-             tural support, in our practice, are better handled with
eratively confirmed healing of both the greater                other options. We suggest this technique as a readily
tuberosity cyst and the rotator cuff (Fig 1B).                 available option with minimal additional time and
                                                               morbidity for the arthroscopic surgeon to consider
                     DISCUSSION                                when faced with a similar clinical dilemma.

   The role that humeral cysts play in rotator cuff tears
                                                                                      REFERENCES
has not been completely elucidated. Whereas humeral
cysts can exist independently of age or rotator cuff            1. Norwood LA, Barrack R, Jacobson KE. Clinical presentation
tear, their presence has also been linked with in-                 of complete tears of the rotator cuff. J Bone Joint Surg Am
creased greater tuberosity porosity and rotator cuff               1989;71:499-505.
disease.5,7,8 In addition, reduced bone density has been        2. Tuite MJ, Toivonen DA, Orwin JF, Wright DH. Acromial
                                                                   angle on radiographs of the shoulder: Correlation with the
cited as a contributing factor for both reduced biologic           impingement syndrome and rotator cuff tears. AJR Am J
healing and increased mechanical failure after rotator             Roentgenol 1995;165:609-613.
cuff repair.6,9                                                 3. Neer CS II. Impingement lesions. Clin Orthop Relat Res
                                                                   1983:70-77.
   Whereas the ideal graft serves osteogenic, osteoin-          4. Hamada K, Fukuda H, Mikasa M, Kobayashi Y. Roentgeno-
ductive, and osteoconductive roles, graft site harvest             graphic findings in massive rotator cuff tears. A long-term
morbidity has been a limiting factor in the utilization            observation. Clin Orthop Relat Res 1990:92-96.
                                                                5. Pearsall AWt, Bonsell S, Heitman RJ, Helms CA, Osbahr D,
of autograft.10,11 With synthetic grafts containing the            Speer KP. Radiographic findings associated with symptomatic
copolymers polylactic acid and polyglycolic acid with              rotator cuff tears. J Shoulder Elbow Surg 2003;12:122-127.
calcium sulfate, it has been shown that as these ma-            6. Galatz LM, Rothermich SY, Zaegel M, Silva MJ, Havlioglu N,
                                                                   Thomopoulos S. Delayed repair of tendon to bone injuries
terials degrade, they can act as a scaffold, allowing for          leads to decreased biomechanical properties and bone loss.
bony ingrowth.12 Given that the contribution and pres-             J Orthop Res 2005;23:1441-1447.
ence of humeral cysts in rotator cuff pathology are not         7. Williams M, Lambert RG, Jhangri GS, et al. Humeral head
                                                                   cysts and rotator cuff tears: An MR arthrographic study. Skel-
entirely clear, any decision to perform treatment has              etal Radiol 2006;35:909-914.
to be weighed carefully against the morbidity and               8. Jiang Y, Zhao J, van Holsbeeck MT, Flynn MJ, Ouyang X,
risks involved. Ideally, an arthroscopic approach with             Genant HK. Trabecular microstructure and surface changes in
                                                                   the greater tuberosity in rotator cuff tears. Skeletal Radiol
min- imal additional risk beyond the already planned               2002;31:522-528.
pro- cedure may prove beneficial. Although                      9. Tingart MJ, Apreleva M, Zurakowski D, Warner JJ. Pullout
arthroscopic approaches utilizing autograft and                    strength of suture anchors used in rotator cuff repair. J Bone
                                                                   Joint Surg Am 2003;85:2190-2198.
allograft have been described previously, both                 10. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft
autograft and allograft have associated morbidity and              harvest donor site morbidity. A statistical evaluation. Spine
risks that must be weighed accordingly.10,11,13-16                 1995;20:1055-1060.
                                                               11. Hill NM, Horne JG, Devane PA. Donor site morbidity in the
                                                                   iliac crest bone graft. Aust N Z J Surg 1999;69:726-728.
                                                               12. Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization,
                   CONCLUSIONS                                     toxicity, biocompatibility and clinical applications of polylac-
                                                                   tic acid/polyglycolic acid copolymers. Biomaterials 1996;17:
   Using a readily available artificial scaffold, avoid-           93-102.
ing the possibility of both graft harvest morbidity and        13. Hangody L, Feczko P, Bartha L, Bodo G, Kish G. Mosaic-
infectious disease transmission, to address a humeral              plasty for the treatment of articular defects of the knee and
                                                                   ankle. Clin Orthop Relat Res 2001:S328-S336 (suppl).
cyst arthroscopically at the time of rotator cuff repair,      14. Burkhart SS, Klein JR. Arthroscopic repair of rotator cuff
to our knowledge, has not been previously reported.                tears associated with large bone cysts of the proximal
Because these scaffolds are not intended to serve a                humerus: Compaction bone grafting technique. Arthros-
                                                                   copy 2005;21:1149.e1-1149.e5. Available online at www.
structural role, their utility in our practice is limited to       arthroscopyjournal.org.
well-circumscribed defects amenable to the creation            15. Caldwell PE III, Shelton WR. Indications for allografts.
of a tubular socket (e.g., humeral cyst, defect in the             Orthop Clin North Am 2005;36:459-467.
                                                               16. Hou CH, Yang RS, Hou SM. Hospital-based allogenic bone
tuberosity after removal of an anchor or hardware, as              bank—10-year experience. J Hosp Infect 2005;59:41-45.

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Rotator cuff-repair

  • 1. Technical Note Arthroscopic Grafting of Greater Tuberosity Cyst and Rotator Cuff Repair Vivek Agrawal, M.D., and Matthew Stinson, P.A.-C. Abstract: Cysts of the greater tuberosity can be a normal finding independent of age and concurrent rotator cuff tear. The presence of a large greater tuberosity cyst can present a challenge at the time of rotator cuff repair. We present a 1-step arthroscopic technique to address these defects at the time of rotator cuff repair using a synthetic graft (OsteoBiologics, San Antonio, TX) originally designed to address osteoarticular defects. With the viewing portal established laterally, a portal allowing perpendicular access to the cyst is established. The cyst is thoroughly debrided, and a drill sleeve is then introduced perpendicular to the surrounding bone, serving as a guide for the matching drill to create a circular socket. A correspondingly sized TruFit BGS cylindrical implant (OsteoBiologics) is then implanted by use of the included instrumentation. The scaffold is placed flush with the surrounding bone. Because our arthroscopic rotator cuff protocol uses a tension-band technique with placement of suture anchors distal and lateral to the rotator cuff footprint, we are subsequently able to proceed with routine rotator cuff repair. Key Words: Rotator cuff repair—Bone graft—Surgical technique—Humeral cyst, shoulder surgery I t is unclear whether cysts within the vicinity of the rotator cuff insertion on the greater tuberosity are developmental, are correlated with age-related time of rotator cuff repair. We present a 1-step arthro- scopic technique to address these defects at the time of rotator cuff repair using porous, resorbable changes, or are specific to rotator cuff pathology.1-4 A scaffolds composed of polylactide– co-glycolide radiographic study of patients with symptomatic and copolymer, providing structure and calcium sulfate surgically documented rotator cuff tears has shown a and promoting bone ingrowth (TruFit BGS Plug; positive correlation with greater tuberosity cysts.5 Ex- OsteoBiologics, San Antonio, TX). perimental work has also cited bone loss as a possible factor in poor healing of rotator cuff repairs.6 The presence of cysts can present a dilemma at the TECHNIQUE AND CASE REPORT A 57-year-old woman slipped and fell onto her outstretched dominant arm, injuring her shoulder. Be- From The Shoulder Center, St. Vincent Hospital, Indianapolis, cause pain and weakness persisted despite conserva- Indiana, U.S.A. tive management, she was referred to our shoulder The authors report no conflict of interest. Address correspondence and reprint requests to Vivek Agrawal, clinic. A thorough radiographic and clinical examina- M.D., The Shoulder Center, 10801 North Michigan Rd, #100, tion revealed the presence of both a rotator cuff tear Zionsville, IN 46077, U.S.A. E-mail: DrAgrawal@TheShoulder and a significant greater tuberosity subcortical cyst Center.com © 2007 by the Arthroscopy Association of North America (Fig 1A). After a thorough review of the risks, bene- Cite this article as: Agrawal V, Stinson M. Arthroscopic grafting fits, and options regarding treatment, along with our of greater tuberosity cyst and rotator cuff repair. Arthroscopy recommendations, the patient was eager to proceed 2007;23:904.e1-904.e3 [doi:10.1016/j.arthro.2006.10.026]. 0749-8063/07/2308-6387$32.00/0 with arthroscopic treatment. We routinely use a semi– doi:10.1016/j.arthro.2006.10.026 lateral decubitus position for arthroscopic shoulder Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 23, No 8 (August), 2007: pp 904.e1-904.e3 904.e1
  • 2. 904.e2 V. AGRAWAL AND M. STINSON FIGURE 1. (A) Preoperative magnetic resonance scan, showing greater tuberosity cyst (arrow) and rotator cuff tear (asterisk). (B) Magnetic resonance scan at 6 months after surgery, showing healed tuberosity cyst (asterisk) and rotator cuff, as well as placement of anchors distal and lateral to rotator cuff footprint (arrow). procedures. For arthroscopic rotator cuff repair, the scopic shaver. A drill sleeve, matching the size of the viewing portal is placed laterally, allowing working defect, was then inserted perpendicular to the sur- portals to be placed circumferentially and providing rounding greater tuberosity, serving as a guide for the an orthogonal view of the tuberosity and rotator cuff matching drill to create a circular socket. A corre- tear. After thorough bursectomy and debridement of spondingly sized TruFit BGS cylindrical implant (Os- devitalized tissue were performed, allowing a clear teoBiologics) was then implanted by use of the view of the size and pattern of the patient’s rotator included instrumentation. The scaffold was placed cuff tear, the humeral cyst was localized and probed. flush with the surrounding bone (Fig 2A). Because our A portal adjacent to the lateral border of the acromion arthroscopic rotator cuff repair protocol uses a tension- allowing perpendicular access to the cyst via spinal band technique with placement of suture anchors distal needle localization was established. The cyst was and lateral to the rotator cuff footprint, we were able to thoroughly debrided to bleeding bone with an arthro- proceed with routine rotator cuff repair (Fig 2B). FIGURE 2. (A) Prepared and grafted defect at greater tuberosity. (B) Placement of anchors distal and lateral to rotator cuff footprint.
  • 3. GREATER TUBEROSITY CYST 904.e3 Postoperatively, the patient was started on our stan- well as a humeral osteochondral defect). Situations dard arthroscopic rotator cuff repair protocol. Mag- requiring the bone graft to provide immediate struc- netic resonance imaging performed 6 months postop- tural support, in our practice, are better handled with eratively confirmed healing of both the greater other options. We suggest this technique as a readily tuberosity cyst and the rotator cuff (Fig 1B). available option with minimal additional time and morbidity for the arthroscopic surgeon to consider DISCUSSION when faced with a similar clinical dilemma. The role that humeral cysts play in rotator cuff tears REFERENCES has not been completely elucidated. Whereas humeral cysts can exist independently of age or rotator cuff 1. Norwood LA, Barrack R, Jacobson KE. Clinical presentation tear, their presence has also been linked with in- of complete tears of the rotator cuff. J Bone Joint Surg Am creased greater tuberosity porosity and rotator cuff 1989;71:499-505. disease.5,7,8 In addition, reduced bone density has been 2. Tuite MJ, Toivonen DA, Orwin JF, Wright DH. Acromial angle on radiographs of the shoulder: Correlation with the cited as a contributing factor for both reduced biologic impingement syndrome and rotator cuff tears. AJR Am J healing and increased mechanical failure after rotator Roentgenol 1995;165:609-613. cuff repair.6,9 3. Neer CS II. Impingement lesions. Clin Orthop Relat Res 1983:70-77. Whereas the ideal graft serves osteogenic, osteoin- 4. Hamada K, Fukuda H, Mikasa M, Kobayashi Y. Roentgeno- ductive, and osteoconductive roles, graft site harvest graphic findings in massive rotator cuff tears. A long-term morbidity has been a limiting factor in the utilization observation. Clin Orthop Relat Res 1990:92-96. 5. Pearsall AWt, Bonsell S, Heitman RJ, Helms CA, Osbahr D, of autograft.10,11 With synthetic grafts containing the Speer KP. Radiographic findings associated with symptomatic copolymers polylactic acid and polyglycolic acid with rotator cuff tears. J Shoulder Elbow Surg 2003;12:122-127. calcium sulfate, it has been shown that as these ma- 6. Galatz LM, Rothermich SY, Zaegel M, Silva MJ, Havlioglu N, Thomopoulos S. Delayed repair of tendon to bone injuries terials degrade, they can act as a scaffold, allowing for leads to decreased biomechanical properties and bone loss. bony ingrowth.12 Given that the contribution and pres- J Orthop Res 2005;23:1441-1447. ence of humeral cysts in rotator cuff pathology are not 7. Williams M, Lambert RG, Jhangri GS, et al. Humeral head cysts and rotator cuff tears: An MR arthrographic study. Skel- entirely clear, any decision to perform treatment has etal Radiol 2006;35:909-914. to be weighed carefully against the morbidity and 8. Jiang Y, Zhao J, van Holsbeeck MT, Flynn MJ, Ouyang X, risks involved. Ideally, an arthroscopic approach with Genant HK. Trabecular microstructure and surface changes in the greater tuberosity in rotator cuff tears. Skeletal Radiol min- imal additional risk beyond the already planned 2002;31:522-528. pro- cedure may prove beneficial. Although 9. Tingart MJ, Apreleva M, Zurakowski D, Warner JJ. Pullout arthroscopic approaches utilizing autograft and strength of suture anchors used in rotator cuff repair. J Bone Joint Surg Am 2003;85:2190-2198. allograft have been described previously, both 10. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft autograft and allograft have associated morbidity and harvest donor site morbidity. A statistical evaluation. Spine risks that must be weighed accordingly.10,11,13-16 1995;20:1055-1060. 11. Hill NM, Horne JG, Devane PA. Donor site morbidity in the iliac crest bone graft. Aust N Z J Surg 1999;69:726-728. 12. Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, CONCLUSIONS toxicity, biocompatibility and clinical applications of polylac- tic acid/polyglycolic acid copolymers. Biomaterials 1996;17: Using a readily available artificial scaffold, avoid- 93-102. ing the possibility of both graft harvest morbidity and 13. Hangody L, Feczko P, Bartha L, Bodo G, Kish G. Mosaic- infectious disease transmission, to address a humeral plasty for the treatment of articular defects of the knee and ankle. Clin Orthop Relat Res 2001:S328-S336 (suppl). cyst arthroscopically at the time of rotator cuff repair, 14. Burkhart SS, Klein JR. Arthroscopic repair of rotator cuff to our knowledge, has not been previously reported. tears associated with large bone cysts of the proximal Because these scaffolds are not intended to serve a humerus: Compaction bone grafting technique. Arthros- copy 2005;21:1149.e1-1149.e5. Available online at www. structural role, their utility in our practice is limited to arthroscopyjournal.org. well-circumscribed defects amenable to the creation 15. Caldwell PE III, Shelton WR. Indications for allografts. of a tubular socket (e.g., humeral cyst, defect in the Orthop Clin North Am 2005;36:459-467. 16. Hou CH, Yang RS, Hou SM. Hospital-based allogenic bone tuberosity after removal of an anchor or hardware, as bank—10-year experience. J Hosp Infect 2005;59:41-45.