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Next generation sequencing & microarray-- Genotypic Technology
 

Next generation sequencing & microarray-- Genotypic Technology

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Greetings from Genotypic Technology, Bangalore (www.genotypic.co.in). We are a 13 year old genomics and bioinformatics company ( 65+ employees, Service. Products and R & D) based in Bangalore, India, ...

Greetings from Genotypic Technology, Bangalore (www.genotypic.co.in). We are a 13 year old genomics and bioinformatics company ( 65+ employees, Service. Products and R & D) based in Bangalore, India, primarily working on applications of Microarrays and Next Generation Sequencing in Human Health and Disease, including in Molecular Diagnostics, Prognosis, Therapeutics, Vaccine Research, Basic Science Research, Veterinary Science, Agriculture, Industrial Biotechnology, Microbial Genetics and more.

Our major strength is in customized genomics solutions, particularly in your field, we can develop panel of markers for specific diseases, optimize, validate and help commercialize on open platforms or specific instrument platforms- in microarrays and sequencing based methods/ assays. We can also use genomic markers to aid in treatment of specific disease using personalized medicine approaches. All this can be done on a comprehensive end-to-end manner in our company as we have a very good blend of molecular biology and bioinformatics with totally 6 Ph.Ds. We work closely with Agilent's R &D as their partner.

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    Next generation sequencing & microarray-- Genotypic Technology Next generation sequencing & microarray-- Genotypic Technology Document Transcript

    • Bridging the Gap between
      Biology and Genomic technologies
      Genotypic Technology
      • Established in 1998 – First Genomics R&D Company in India.
      • Pioneered Microarrays and Next Generation Sequencing Services.
      • Well equipped with cutting edge technologies to handle large scale genomics projects.
      • Our core strength is customization and new application development.
      • Team Genotypic has 8 PhDs and more than 60 Masters.
      • Teams: qPCR & Molecular biology lab, Certified Microarray Lab, NGS lab, Array Design informatics, Microarray Analysis, NGS Analysis.
      • With 2 GAIIx sequencers we specialize in long reads >140 base paired end short turnaround times
      • We specialize in custom arrays and non standard application
      Follow us
      Largest NGS and Microarray Group in Linkedin – managed by Genotypic
      www.linkedin.com/groups?about=&gid=1907871&trk=anet_ug_grppro
      Plant breeding & Genetics AND Agri Genomics
      www.linkedin.com/groups?mostPopular=&gid=3186656
      Released on 1st March 2011
      ISO 9001:2008 Certified Laboratory
    • MicroarrayServices
      Certified Microarray services with
      GUARANTEED RESULTS
      8 x 15K format
      8 x 60K format
      • Gene Expression Profiling (including non coding RNAs)
      • Cancer genomics
      • miRNAprofiling and small RNAs
      • Plant / AgriGenomics
      • Alternative Splice Variants
      • Bovine / Cattle Genomics
      • ChIP on chip & DNA Methylation
      • Toxicogenomics / Clinical genomics
      • aCGH (Comparative Genomics)
      • Biomarker Discovery / Epigenetics
      • CNV(Copy Number Variations)
      • Bacterial Biosensors
      • SNP Validation Arrays
      • Drug re-purposing/ Drug target discovery
      • InDELs (Insertions & Deletions)
      4x 44K format
      4x 180K format
      1 x 244K format
      1 x 1M format
      2 x 105K format
      2 x 400K format
      - New
      High resolution scanning and
      automated feature extraction with guaranteed high quality results
      Custom Design Arrays
      Any organism, Any sequence, Any application
      NO SETUP FEES! NO MINIMUM ORDER!
      Statistical analysis
      Biological analysis
      High quality RNA / DNA
      extraction and quality control
      Have an Idea? Talk to us!
      We have the right solution and technology to translate your ideas into results! Write to us at genomics@genotypic.co.in
      Ready to use arrays available for most bacteria, fungi, lower eukaryotes, insects, fish, plants, mammals and many more…
      www.genotypic.co.in/micro_arrays.html
      Catalog OR Custom microarray slide
    • Next Gen Sequencing Services (NGS)
      Next Generation Sequencing has revolutionized Biological Research
      Power of NGS
      • More than 100 times economical than Sanger sequencing
      • Extremely High throughput- Sequence 100s of bacterial, small organism genomes
      • Sequence complete human genome in a week
      • DNA, RNA Sequencing of organisms with little or no reference information available
      • Data from NGS studies can be used to custom design unique microarrays
      NGS Technological applications
      • Whole genome sequencing
      • Targeted Re-sequencing
      • SNP, Mutation identification
      • Transcriptome sequencing
      • Digital gene expression
      • ChIP sequencing
      • Methylome sequencing
      • Small RNA sequencing
      Popular NGS Themes
      • Bacterial and other microbial sequencing- De-novo and Re-sequencing
      • Human Genetics- Disease Inheritance studies
      • Transcriptome/RNA sequencing
      • Metagenomics
      • Agrigenomics
      • Pathogen detection in host system
      • ChIPSeq combined with ChIP on chip microarrays. Discover and validate Novel protein binding regions.
      Targeted Re-sequencing using Agilent SureSelect
      Sequence regions that matter…
      Agilent SureSelect Capture
      Targeted Re-sequencing @ Genotypic
      • Full service available for all organisms
      • Sequence selected genes / genomic regions in multiple samples combined with DNA Capture using Agilent SureSelect Technology - On-Array DNA Capture and In-Solution (Liquid) Capture
      • Sample/ Library preparation, Multiplexing
      • Compatible with all NGS platforms.
      List of Genes, Exons, Genomic regions/ Choose from catalog DNA Capture designs
      Baits Insolution
      Capture Microarray
      Genomic DNA
      Hybridization
      Elution of Captured Material
      Fragmentation (Sonication / Shearing)
      Enrichment by qPCR
      Repair ends
      Captured DNA ready for Shearing
      Ligate adapters
      At Genotypic we have successfully completed more than 200 NGS projects resulting in > 20 publications.
    • QC, UNDERSTAND, ANALYSE, INTERPERT, APPLY
      Efficient Analysis of High Throughput Genomics Data
      “Any platform, Any format, Any application”
      “Align  Assemble  Annotate  Analyze”
      MICROARRAY DATA ANALYSIS
      COMPREHENSIVE NGS DATA ANALYSIS
      Genotypic Technology provides the complete microarray data analysis services for Gene expression data generated using any platform. The end-point of analysis includes Biological interpretation of differentially regulated genes into significant functional categories and pathways. Our Reports Include publication quality charts and graphs.
      Sequence Data (Reads)
      Reference Sequence (Optional)
      QC on Reference
      QC on Reads
      PRELIMINARY DATA ANALYSIS SERVICE
      QC Report of reads and reference sequences
      (Min/Max/Median Read Length, No. & % of HQ Reads, No. & % of HQ Bases, No. & % of NON ATGC Bases)
      Start Point:
      Raw Data (.txt, .cel files accepted)
      Deliverables :
      QC reports, List of differentially regulated genes/ Enriched probes with detailed annotation. Significant Gene ontology categories with p-value, Significant pathways regulated with p-value.
      Time taken – 3 Days
      Alignment Statistics
      (% Coverage, % of mapped and unmapped reads, Avg. Read Depth, No. & Length of Gaps, Avg. Gap Length)
      CUSTOM DATA ANALYSIS SERVICE
      Start Point :
      RawData (.txt, .cel files accepted)
      Deliverables:
      Image QC, Raw Data QC, Raw Data,
      Differentials / Enriched probes with detailed annotation, Significant Gene ontology categories with p-value, Significant pathways regulated with
      p-value, spreadsheet with gene vs client requested key words with publication evidences.
      Time taken – 5 Days
      De Novo Genome assembly
      Small RNA Assembly
      15th April 2011
      Variation Analysis
      BIOLOGICAL ANALYSIS SERVICE
      ChIPseq Analysis
      Start Point :
      Gene list & Keywords
      Deliverables:
      Literature curated gene
      Vs
      keyword relationship.
      Time taken – 5 Days
      Transcriptome Analysis
      Simple Desktop Application for Rapid Quality Control and Reporting of NGS Data and Processed Sequence Files
      www.genotypic.co.in/SeqQC.html
      Project Planning till Publication Quality Reports,
      End to End NGS and MICROARRAY services at Genotypic
      NGS – Microarray Lab / Analysis
      Training / Workshops
      www.nextgenseq.com/register
      Tools for interpretation of Data
      www.genotypic.co.in/products.html
      Genotypic’sclientele, collaborators include Indian Institute of Science, UNILEVER, Astra Zenca, Evogene, JNU, IMTECH, Biocon, WiezmannInstitue, Quark Pharma, Novartis, Harvard University…
      Genotypic Technology Pvt. Ltd.
      #259, Apurva, RMV 2nd Stage, 80 Feet Road, Bangalore – 560094, India
      Ph: +91-80-40538200 Fax: +91-80-40538222,USA Phone: +1-(215) 253 4495
      Website: www.genotypic.co.in, E-mail: genomics@genotypic.co.in