Jaundice classification in adults summary

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Jaundice classification in adults summary

  1. 1. JaundiceIncreased Bilirubin Production Impaired Bilirubin Excretion1. Hemolytic anaemia ABO incomp. Congenital Non-hemolytic Cholestatic Rhesus incomp. ↑bilirubin Spherocytosis Gilbert’s syndrome Elliptocytosis Crigler-Najjar Types I & II Intrahepatic Extrahepatic G6PD def Rotor syndrome Pyruvate kinase def Dubin-Johnson syndrome AIHA 1. Primary biliary cirrhosis 1. Choledocholithiasis Mechanical trauma: 2. Primary Sclerosing 2. CA prosthetic valves, cholangitis Ampulla hypersplenism, DIC 3. Viral hepatitis Pancreas2. Dyserythropoiesis 4. Alcohol Bile duct Megaloblastic anaemias 5. Drugs (cholangioCA) Sideroblastic anaemias 6. Autoimmune hepatitis Secondary3. Breakdown of large 7. Wilson’s dz 3. Trauma to biliary hematomas 8. α1-antitrypsin deficiency structures4. Sepsis 9. Severe bacterial infection 4. Fibrosis (eg postop)5. Drugs 10. Pregnancy 5. Cystic fibrosis 11. Idiopathic recurrent 6. Parasitic infection cholestasis *may result in ascdingUnconjugated ↑bilirubin cholangitisConjugated ↑bilirubinUC and C ↑bilirubin Digitally signed by DR WANA HLA SHWE DN: cn=DR WANA HLA SHWE, c=MY, o=UCSI University, School of Medicine, KT-Campus, Terengganu, ou=Internal Medicine Group, email=wunna. hlashwe@gmail.com Reason: This document is for UCSI University, School of Medicine students. Date: 2009.02.24 14:26:22 +0800

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