Orthopedic Instrumentation - A Global Market Perspective

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Orthopedic Instrumentation - A Global Market Perspective
Published on November 2009

Report Summary

Demand for orthopedic instrumentation products is driven by considerable rise in osteoporosis, arthritis, and joint diseases. An aging
population, increasingly active lifestyles, and an expanding obese population are factors favoring demand for orthopedic implants.
Unique revolutionary treatments are all set to alter the specifics of medical orthopedics industry. With increase in average life
expectancy rates, number of joint replacement procedures has reported significant growth. Sports-related injuries in the younger
generation, and growing popularity of minimally invasive surgery are fuelling the demand for joint replacement surgeries. Companies
across the world are focusing on the development of advanced materials and technologies in the field of orthopedic implants, to
address the emerging requirements of aging population and active youth.

These and other market data and trends are presented in "Orthopedic Instrumentation: A Global Market Perspective" by BizAcumen,
Inc. Our reports are designed to be most comprehensive in geographic coverage and vertical market analyses.

Table of Content

ORTHOPEDIC INSTRUMENTATIONBMR-1093

CONTENTS

1. METHODOLOGY 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Quantitative Techniques & Reporting Level 3

2. GLOBAL MARKET OVERVIEW AND OUTLOOK 4
Emerging Technologies-Redefining the Future 4
Industry Dynamics and Changing Scenario 4
Current & Future Analysis 5
Growth Drivers, Trends & Issues 5
Aging Population Drives Demand 5
Prevalence of Osteoporosis, Arthritis and other Joint
Diseases Fuel Market Growth 6
Obesity - Another Catalyst to Growth 6
Increasing Life Expectancy Rates 7
Cost Containment Issues 7
Developing Markets - High Potential 7
Revision Procedures Buoy Growth 8

Orthopedic Instrumentation - A Global Market Perspective Page 1/14


Minimally Invasive Surgery - Attracts Attention 8
Advanced Materials & Technologies Foster Growth 8
Advanced Coatings - Enhancing Lifespan of Implants 9
Demand for Premium Implants Continues 9
Growing Demand for Total Hip Replacement in Young People 10
Hip Resurfacing Replacement - for Younger Generation 10
Gender-Specific Orthopedic Devices Gain Momentum 11
Spinal and Orthobiologics Products Spearhead Growth 11
Synthetic Substitutes, Growth Factors and Composites 12
Stem Cell and Gene Therapy 12
Growing Presence of Mid-Tier Firms & Start-Ups in Spinal Segment 13
Focus Shifts to External R&D Operations 13
Rising Production Costs & Complexities in Documentation -
Major Challenges 13

3. PRODUCT FACTS 14
A. Reconstructive Sector 14
Hip Implants 14
Knee Implants 14
Extremities 15
B. Fracture Fixation 15
C. Arthroscopy 15
D. Spinal Products 15
E. Other Products 15

4. MARKET OUTLOOK BY PRODUCT SEGMENT 16
A. Reconstructive Market 16
Highlights 16
Countering Rising Hip Implant Prices 17
Tooth 'N Trouble 17
Future of Reconstructive Sector 17
B. Fracture Fixation 18
Osteoporosis - A Bone Breaking Factor 18
Trends and Developments in the Fracture Fixation Market 19
Novel Technologies Boost External Fixation Device Market 19
Increase in Less Invasive Fracture Repair Procedures 19
New Technologies Rekindle Market for Trauma Products 19
Intramedullary Nails Threatened by LCP Systems 20
Locking Compression Plates Might Lose its Superfluous Growth 20
Aging Population and Active Life Styles Offer Steady Growth 21
C. Arthroscopy Market 21
D. Spinal Implants and Instrumentation 21
Spinal Fusion - Lending Support to the Troubled Backs 22
Spinal Implants Market: Primary Growth Drivers 22
State of Spinal Fusion Cages 22
Emerging Technologies and Techniques 22
Non- Invasive Surgeries 23
Universal Multilevel Fusions 23
Motion-Sparing Technology - Leap Forward in Spinal Fusions 23
Artificial Nuclei 23



Market Analysis 25
E. Other Products 25
Bone Cement 25
Soft Goods Sector 26

5. M & A ACTIVITY: 2007-2008 IN ORTHOPEDIC INSTRUMENTATION SEGMENT 26

6. COMPETITION 27
Advancement in Power Surgical Products 28
Competitive Factors Influencing Orthopedics Market 28
Positive Factors 28
Pricing and Cost Effectiveness of Products 28
Consumer Relationships 28
Safety and Competency of Products 29
Technological Advancements 29
Product Innovation 29
Risk Factors 30
Delays in Product Development 30
Time Taken for Regulatory Approvals 30
Competitive Analysis 30
Product Matrix of Leading Players in Orthopedics Industry 31
Reconstructive Sector 31
Hip Implants 32
Knee Implants 33
Extremities 34
Fracture Fixation 34
Internal Fixation 34
External Fixation 34
Arthroscopy 35
Spinal Products 35

7. TECHNOLOGICAL DEVELOPMENTS 36
Alternate-Bearing Materials in the Hip Implants Market 36
Diamond-on-Diamond Technology 37
Cementless Procedures Gain Ground 37
Trabecular Metal Technology 38
Surface Modification Technology 38
Novel Minimally Invasive Approaches 38
Zimmer Launches Quad-Sparing Total Knee Replacement 38
Spire's Subsidiary Expands Ion Implantation Processing 38
Zimmer to Launch New Minimally Invasive Hip Procedure 39
DePuy Introduces New Mini-Incision Technique in Hip Replacement 39

8. CORPORATE DEVELOPMENTS 39
Wright Medical Takes Over INBONE Technologies 39
Riverside Acquires Summit Medical 40
Regeneration Technologies and Tutogen Merge to Form RTI Biologics 40
Precimed Acquires DePuy Orthopaedics' Chaumont Plant 40
Symmetry Medical Acquires Orthopaedic Instrument Facility of
DePuy 41



Tornier and LifeCell Sign Distribution Agreement 41
Osteotech Enters into Distribution Agreement with Harvest
Technologies 41
Exactech Inks License Deal for Cartilage Repair Technology 42
Biomet Ties Up with Massachusetts General Hospital for
Clinical Studies 42
Stryker Recalls Select Hip Products 43
Wright Medical Introduces Titanium Knee Implant 43
Medtronic Introduces NANOSTIM® Synthetic Bone Paste 43
CONMED Unveils Medical Devices 43
DePuy Unveils Pinnacle Hip Solutions 44
Smith & Nephew Introduces VERILAST' Technology 45
DePuy Expands Sigma® Knee Product Portfolio 45
Smith & Nephew Introduces R3' Acetabular Cup System for Hip
Replacement 45
Smith & Nephew Launches Bioraptor 2.3 PK Suture Anchor 45
Wright Medical Group Launches Profemur Xm Hip Stem 46
Stryker Introduces Triathlon PKR System in the US 46
DePuy Launches ALPS for Orthopaedic Trauma 46
DJO Surgical Gains FDA Approval to Market New X-alt 46
Osteotech Obtains FDA Clearance for Plexur M Biocomposite 47
ConforMIS Wins CE Mark Approvals for Two Arthritis Products 47
Biomet Merges with LVB Acquisition Merger Sub 47
Cardinal Health Completes Acquisition of VIASYS Healthcare 48
Biomet Sports Medicine and Marc Tec Ink Licensing Agreement 48
Sandvik Inks Agreement with Medtronic to Acquire Medtronic's
Plant 48
Medtronic and Weigao to Establish Joint Venture in China 49
HealthpointCapital Takes over Ideal Medical Products 49
Covidien's Subsidiary Takes Over Scandius Biomedical 50
DePuy Spine Completes Acquisition of Certain Disc-O-Tech Assets 50
Wright Medical Acquires BIO-ARCH' Subtalar Implant 50
Orthofix International Completes Acquisition of InSWing'
Technology 51
Medtronic Completes Acquisition of Kyphon 51
Tornier Takes Over DVO Extremity Solutions & Nexa Orthopedics 51
Medtronic Takes over O-arm Imaging from Breakaway Imaging 52
Wright Medical Takes over Assets of R&R Medical 52
Wright Medical Acquires DARCO's Reconstructive Foot Surgery
Business 52
Zimmer Holdings Acquires Endius 53
Leis Medical and MedicineLodge Merge to Form iMDs 53
Zimmer Takes Over ORTHOsoft 53
DJO Completes ReAble Merger 54
Smith & Nephew Acquires Plus Orthopedics 54
Synthes Takes Over N Spine 54
Wright Medical and A.M. Surgical in Distribution and License
Agreement 55
Symmetry Medical and MAKO Surgical Enter into an Agreement 55
Medtronic and Axon Enter into Agreement 55



Wright Medical Shuts Down Facility in France 56
Tornier and Bioretec in Partnership for Bioresorbable Surgical
Devices 56
Smith & Nephew Signs Global Distribution Agreement with Teknimed 56
Biomet and Kensey Signs Marketing and Distribution Agreement 57
Smith & Nephew Recalls Knee Implants 57
Smith & Nephew Unveils New High Definition Surgical Camera System 57
Wright Medical Introduces a New Biologic Grafting System 57
Wright Medical Unveils Hip Solutions Products 58
Smith & Nephew Introduces Bi-Compartmental Knee System 58
DePuy Introduces Computer Software for Assisting Surgery 58
Medtronic Launches CD Horizon® Legacy' Anterior Spinal System 58
Depuy Orthopaedics Unveils New Coating for Biological Fixation 59
DePuy Introduces Delta Xtend' Reverse Shoulder System 59
DePuy Launches New System for Hip Fractures 59
DePuy Introduces New Hip-Bearing System 59
DePuy Introduces Pinnacle® Acetabular Cup System AltrX' 60
Biomet Introduces Two New Hip Stem Products 60
Smith & Nephew Endoscopy Introduces New Lateral Hip Distractor 60
Wright Medical Launches Latest Stature-Specific Knee Replacement 60
Integra LifeSciences Introduces Uni-CP Compression Plate 61
Wright Medical Introduces the CAROLINA' Jones Fracture 61
Wright Medical Launches EVOLVE® PROLINE System 61
Smith & Nephew's Knee Systems Receive FDA Approval 61
Zimmer Obtains FDA Approval for Zimmer® NexGen® Knee 62

9. MAJOR PLAYERS 62
Acumed LLC (US) 62
Arthrex, Inc. (US) 63
Biomet, Inc. (US) 63
Conmed Corp. (US) 63
DJO Surgical (US) 64
Exactech, Inc. (US) 64
Innomed, Inc. (US) 64
Johnson & Johnson (US) 64
DePuy Inc. (US) 65
Medtronic Sofamor Danek, Inc. (US) 65
Orthofix International N.V. (The Netherlands) 65
Smith and Nephew Plc (UK) 66
Stryker Corporation (US) 66
Synthes, Inc. (Switzerland) 67
Wright Medical Technology, Inc. (US) 67
Zimmer Holdings, Inc. (US) 67

10. MARKET ANALYTICS 68

11. THE UNITED STATES 75
United States - The Largest Orthopedics Market 75
An Overview of the US Orthopedic Healthcare System 75
Trends & Issues 76



Aging Population & Obesity Drive Demand for Orthopedic
Procedures 76
Technological Developments Promote Growth 76
Biomaterials Market - Keeping Pace with Changing Times 77
Orthopedic Soft Tissue Allograft Market in the US 77
Rising Incidence of Arthritis Aids Growth in Implant Procedures 77
Orthopedic Implants Market in the US 78
Wear Debris-A Major Concern 79
Reimbursement Scenario 79
CMS Implements MS-DRG System 79
Reconstructive Market Overview 80
Large Joint Reconstructive Implants Market - An Overview 80
Aging Population Demographics 81
Arthritis: Stats 82
Joint Replacement Procedures - Improving Technologies &
Materials 82
Knee Implants Market 82
Knee Implant Pricing Scenario 83
Hip Implants Market 83
New Materials Emerge as Polyethylene Alternatives 84
Shift from Cemented to Press-Fit Procedures 84
Cost Containment for Implants 85
Fracture Fixation Market 85
Shift Towards LCPs Drive Growth 85
Arthroscopy Market 86
New Technologies Fuel Arthroscopy Market 86
Spinal Products Market 86
Troubled Backs 87
Spinal Procedures in US Witness Substantial Growth 88
Artificial Disc Replacement 88
Bone Graft Market 89
Competitive Landscape 90

12. CANADA 93
Orthopedics Market - An Overview 93
Growth Drivers 93
US Players Dominate the Maxillofacial Market 94
Increasing Incidence of Arthritis Triggers the Demand for Hip
& Knee Implants 95
Spinal Implant Market in Canada 95
Socio-Economic Factors 95
Highly Consolidated Market 95

13. JAPAN 97
Driven by Innovations 97
Aging Population Propels Sales 97
Reimbursement Scenario 97
Spinal Implant Market - Opportunities Galore 98
Players in Japanese Orthopedic Implants Market 98



14. EUROPE 100

a. France 107

b. Germany 108

c. Italy 111

d. The United Kingdom 112

e. Spain 114

f. Rest of Europe 116

15. ASIA-PACIFIC 122
Asia - A Promising Market for Orthopedic Device Manufacturers 122
Asian Orthopedic Markets: Entry Barriers 122
Review of Select Markets 123
Australia 123
China 123
India 125
Joint Implants Market - Set for Rapid Growth 125
Medical Tourism Bolsters Orthopedic Implants Market 126
South Korea 126
Taiwan 128
Thailand 128

16. LATIN AMERICA 130
Argentina 130
Brazil 130
Ecuador 131
Mexico 131

17. REST OF WORLD 133
Israel 133

EXHIBITS

Table 1: Market Shares of Leading Orthopedic Instrumentation
Manufacturers in the World - 2007

Table 2: Market Shares of Leading Reconstructive Implants

Table 3: Market Shares of Leading Hip & Knee Replacement
Devices Manufacturers in the World - 2008E

Table 4: Market Shares of Leading Hip Implants Manufacturers
in the World 2008E



Table 5: Market Shares of Leading Knee Implants Manufacturers
in the World -2007

Table 6: Market Shares of Leading Extremities Manufacturers in
the World - 2005

Table 7: Market Shares of Leading Trauma & Craniomaxillofacial
Devices Manufacturers in the World - 2007

Table 8: Market Shares of Leading Arthroscopy Devices

Table 9: Market Shares of Leading Spinal Implants
Manufacturers in the World - 2008E

Table 10: Market Shares of Leading Orthobiologics

Table 11: Global Orthopedic Instrumentation Market by Region
for the Period 2007-2015 (Sales in US$ Million)

Table 12: Percentage Breakdown of Global Orthopedic
Instrumentation Market by Region for the Years 2008 & 2012

Table 13: Global Reconstructive Sector Market by Region for
the Period 2007-2015 (Sales in US$ Million)

Table 14: Percentage Breakdown of Global Reconstructive Sector
Market by Region for the Years 2008 & 2012

Table 15: Global Reconstructive Sector Market by Segment for
the Period 2007-2015 (Sales in US$ Million)

Table 16: Percentage Breakdown of Global Reconstructive Sector
Market by Segment for the Years 2008 & 2012

Table 17: Global Fracture Fixation Market by Region for the
Period 2007-2015 (Sales in US$ Million)

Table 18: Percentage Breakdown of Global Fracture Fixation

Table 19: Global Arthroscopy Market by Region for the Period
2007-2015 (Sales in US$ Million)

Table 20: Percentage Breakdown of Global Arthroscopy Market by
Region for the Years 2008 & 2012

Table 21: Global Spinal Products Market by Region for the



Period 2007-2015 (Sales in US$ Million)

Table 22: Percentage Breakdown of Global Spinal Products

Table 23: Global Other Orthopedic Instrumentation Products
Market by Region for the Period 2007-2015 (Sales in US$
Million)

Table 24: Percentage Breakdown of Global Other Orthopedic
Instrumentation Products Market by Region for the Years 2008
& 2012

Table 25: Market Shares of Knee Implants in the US - 2004

Table 26: Market Shares of Leading Reconstructive Implants
Manufacturers in the US - 2007

in the US - 2007

Table 28: Market Shares of Leading Knee Reconstruction

Table 29: Market Shares of Leading Fracture Fixation Devices


Table 31: Orthopedic Instrumentation Market by Segment in the
US: 2007-2015 (Sales in US$ Million)

Table 32: Percentage Breakdown of Orthopedic Instrumentation
Market by Segment in the US for the Years 2008 & 2012

Table 33: Orthopedic Instrumentation Market by Segment in
Canada: 2007-2015 (Sales in US$ Million)

Market by Segment in Canada for the Years 2008 & 2012

in Japan - 2004

Table 36: Market Shares of Leading Fracture Fixation Devices
Manufacturers in Japan - 2004

Japan: 2007-2015 (Sales in US$ Million)



Market by Segment in Japan for the Years 2008 & 2012

in Europe - 2004

in Europe - 2004

Table 41: Orthopedic Instrumentation Market by Region in
Europe: 2007-2015 (Sales in US$ Million)

Market by Region in Europe for the Years 2008 & 2012

Europe: 2007-2015 (Sales in US$ Million)

Market by Segment in Europe for the Years 2008 & 2012

France: 2007-2015 (Sales in US$ Million)

Market by Segment in France for the Years 2008 & 2012

Germany: 2007-2015 (Sales in US$ Million)

Market by Segment in Germany for the Years 2008 & 2012

Italy: 2007-2015 (Sales in US$ Million)

Market by Segment in Italy for the Years 2008 & 2012

Table 51: Orthopedic Instrumentation Market by Segment in the
UK: 2007-2015 (Sales in US$ Million)

Market by Segment in the UK for the Years 2008 & 2012

Spain: 2007-2015 (Sales in US$ Million)




Market by Segment in Spain for the Years 2008 & 2012

Manufacturers in Czech Republic - 2004

Manufacturers in Hungary - 2004

Manufacturers in Poland - 2004

Table 58: Orthopedic Instrumentation Market by Segment in Rest
of Europe: 2007-2015 (Sales in US$ Million)

Market by Segment in Rest of Europe for the Years 2008 & 2012

Manufacturers in China - 2004

in Korea - 2004

in Korea - 2004

Asia-Pacific (excluding Japan): 2007-2015 (Sales in US$
Million)

Market by Segment in Asia-Pacific (excluding Japan) for the
Years 2008 & 2012

Manufacturers in Brazil - 2004

Manufacturers in Mexico - 2004

Latin America: 2007-2015 (Sales in US$ Million)

Market by Segment in Latin America for the Years 2008 & 2012

Table 69: Orthopedic Instrumentation Market by Segment in Rest
of World: 2007-2015 (Sales in US$ Million)




Market by Segment in Rest of World for the Years 2008 & 2012

COMPANIES PROFILED



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