IntroductionThis report examines the opportunities presented to the developers of molecular diagnostics by the emergence of novel/variant pathogens and ways in which new molecular testing technologies are being translated into superior diagnostic products in areas such as healthcare-associated infections; HPV infections, blood-borne viral infections and respiratory viral infections.Features and benefits* Understand the nature and limitations of traditional molecular diagnostics and the improved features of molecular testing technologies in development.* Evaluate the competitive landscape in infectious disease molecular diagnostics and identify potential licensing/collaborative partners.* Analyze the factors stimulating increased demand for molecular testing in specific infectious disease areas to inform investment decisions.* Gain an insight into new and untapped opportunities revealed by recent research findings in the more mature sectors of the MDx market.* Identify key trends in the MDx market and plan future developments with the aid of market forecasts for the individual segments of the market.HighlightsThe latest molecular diagnostics to enter development are multiplex tests which can identify several pathogens or variants of these pathogens present in small-volume samples. Low- and medium-density bead-based microarrays are being developed and are expected to play an increasingly important role in multiplex pathogen detection and genotyping.It is likely that future diagnostic tests will target many more pathogens than is currently the case. Promising approaches include miniaturized microfluidic systems, in particular continuous-flow droplet-based PCR systems, and mass spectrometry-based detection methods which use direct specimen testing and virtually no reagents.Growth forecasts are derived for key MDx market segments for the period 2010-2015: the HPV testing market is forecast to grow with a 5-year CAGR of 20%, the hospital-associated infection (HAI) testing market is forecast to grow with a 5-year CAGR of 19%. and the virology (HIV/HCV/HBV) testing market is forecast to grow with a 5-year CAGR of 8%.Your key questions answered* Which are the areas of unmet need in infectious disease testing and potential new areas of opportunity for MDx in infectious disease'* What forces are shaping molecular diagnostic testing trends and what drivers and restraints operate in the infectious disease testing market'* Who is developing new innovative products for the infectious disease MDx market and what paths to commercialization are they following'* How are the different sectors of the infectious disease MDx market forecast to develop and what are the prospects for new market entrants'* What are the estimated current market sizes and 5-year growth forecasts for the expanding sectors of the infectious disease MDx market'

1. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
Innovations in Molecular Diagnostics for Infectious Diseases
Published on November 2011
Report Summary
Introduction
This report examines the opportunities presented to the developers of molecular diagnostics by the emergence of novel/variant
pathogens and ways in which new molecular testing technologies are being translated into superior diagnostic products in areas such
as healthcare-associated infections; HPV infections, blood-borne viral infections and respiratory viral infections.
Features and benefits
* Understand the nature and limitations of traditional molecular diagnostics and the improved features of molecular testing
technologies in development.
* Evaluate the competitive landscape in infectious disease molecular diagnostics and identify potential licensing/collaborative
partners.
* Analyze the factors stimulating increased demand for molecular testing in specific infectious disease areas to inform investment
decisions.
* Gain an insight into new and untapped opportunities revealed by recent research findings in the more mature sectors of the MDx
market.
* Identify key trends in the MDx market and plan future developments with the aid of market forecasts for the individual segments of
the market.
Highlights
The latest molecular diagnostics to enter development are multiplex tests which can identify several pathogens or variants of these
pathogens present in small-volume samples. Low- and medium-density bead-based microarrays are being developed and are
expected to play an increasingly important role in multiplex pathogen detection and genotyping.
It is likely that future diagnostic tests will target many more pathogens than is currently the case. Promising approaches include
miniaturized microfluidic systems, in particular continuous-flow droplet-based PCR systems, and mass spectrometry-based detection
methods which use direct specimen testing and virtually no reagents.
Growth forecasts are derived for key MDx market segments for the period 2010-2015: the HPV testing market is forecast to grow with
a 5-year CAGR of 20%, the hospital-associated infection (HAI) testing market is forecast to grow with a 5-year CAGR of 19%. and the
virology (HIV/HCV/HBV) testing market is forecast to grow with a 5-year CAGR of 8%.
Your key questions answered
* Which are the areas of unmet need in infectious disease testing and potential new areas of opportunity for MDx in infectious
disease'
* What forces are shaping molecular diagnostic testing trends and what drivers and restraints operate in the infectious disease testing
market'
* Who is developing new innovative products for the infectious disease MDx market and what paths to commercialization are they
following'
* How are the different sectors of the infectious disease MDx market forecast to develop and what are the prospects for new market
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 1/6

2. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
entrants'
* What are the estimated current market sizes and 5-year growth forecasts for the expanding sectors of the infectious disease MDx
market'
Table of Content
Executive Summary
Molecular diagnostic technologies
Healthcare-associated infections
Sexually transmitted HPVs
HIV and hepatitis viruses
Viral respiratory pathogens
Market outlook and forecasts
About the author
Disclaimer
Molecular diagnostic technologies
Summary
Role of molecular diagnostics in infectious diseases
Overview of nucleic acid testing (NAT)
Sample processing
Probe-based testing
Innovations in nucleic acid amplification technologies
PCR-based amplification technologies
Alternative amplification technologies
Automated platforms for NAT
Point-of-care real-time PCR testing systems
Microfluidics
Digital PCR
Innovations in nucleic acid microarrays
Development of microarray formats
Suspension bead and other 3D arrays
Innovations in next-generation sequencing
Innovations in mass spectrometry methods
Innovations in protein arrays
Healthcare-associated infections
Summary
The challenge of drug-resistant pathogens
MRSA
Culture vs. nucleic acid tests
FDA-approved nucleic acid tests
Examples of technologies and products in development
Clostridium difficile
Traditional tests
FDA approved nucleic acid tests
Vancomycin-resistant enterococci (VRE)
Culture and nucleic acid tests
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 2/6

3. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
Bloodstream pathogens
Blood culture
Microorganisms found in blood cultures
FDA-approved nucleic acid tests
Amplification-based products in development
Mass spectrometry-based products in development
Sexually transmitted HPVs
Summary
HPV infections
The HPV genome
Screening for cervical cancer
Analytical versus clinical sensitivity of HPV tests
Genotyping HPV in clinical specimens
Vaccination and implications for testing
Products on the market and in development
Target amplification techniques
Reverse line blot and linear array tests
Amplicor
PapilloCheck
Bead-based assays
Assays using real-time PCR amplification
Signal amplification techniques
Hybrid Capture 2 assay (FDA-approved)
Cervista (FDA-approved)
Detection of HPV mRNA
Nuclisens
Aptima HPV (FDA-approved)
HIV and hepatitis viruses
Summary
Introduction
HIV infections
Characteristics of HIV
HIV testing strategies
HIV load testing
FDA-approved assays
Tests in development
Digital PCR approach
Drug resistance testing
HBV infections
Characteristics of HBV
HBV load testing
Drug resistance testing
Detection of co-infecting HDV
HCV infections
Characteristics of HCV
HCV load testing
Drug resistance and drug efficacy testing
FDA-approved blood screening tests
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 3/6

4. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
Occult HBV and HCV infections
HCV-RNA assays
HBV-DNA assays
Viral respiratory pathogens
Summary
Introduction
Important respiratory viruses
Influenza A/B viruses
Respiratory syncytial virus
Human parainfluenza virus
Adenovirus 1
Rhinovirus
Emerging respiratory viruses
Avian influenza and influenza A swine flu
SARS-covirus and other human coronaviruses
Human metapneumovirus
Human bocavirus
Multiplex respiratory virus panels
Influenza virus panels
Respiratory virus panels
Luminex's xTAG RVP
Qiagen's RespPlex II
EraGen Biosciences' MultiCode-PLx RVP
Comparison of xTAG, ResPlex II, and MultiCode-Plx
AutoGenomics' Infiniti System
Seegene's Seeplex RP Assay
Idaho's real-time PCR FilmArray
BD's real-time PCR Jaguar System
PrimeraDx's quantitative PCR STAR technology
Abbott's PLEX-ID for pathogen discovery
Market outlook and forecasts
Summary
Introduction
MDx opportunities in viral hemorrhagic fevers
MDx opportunities in other emerging pathogens
Multiplexed MDx technology trends
Microarrays and microfluidic devices
Mass spectrometry
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 4/6

5. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
Fax Order Form
To place an order via fax simply print this form, fill in the information below and fax the completed form to:
Europe, Middle East and Africa : + 33 4 37 37 15 56
Asia, Oceania and America : + 1 (805) 617 17 93
If you have any questions please visit http://www.reportlinker.com/notify/contact
Order Information
Please verify that the product information is correct and select the format(s) you require.
Innovations in Molecular Diagnostics for Infectious Diseases
Product Formats
Please select the product formats and the quantity you require.
1 User License--USD 3 835.00 Quantity: _____
Corporate License--USD 14 381.25 Quantity: _____
Contact Information
Please enter all the information below in BLOCK CAPITALS
Title: Mr Mrs Dr Miss Ms Prof
First Name: _____________________________ Last Name: __________________________________
Email Address: __________________________________________________________________________
Job Title: __________________________________________________________________________
Organization: __________________________________________________________________________
Address: __________________________________________________________________________
City: __________________________________________________________________________
Postal / Zip Code: __________________________________________________________________________
Country: __________________________________________________________________________
Phone Number: __________________________________________________________________________
Fax Number: __________________________________________________________________________
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 5/6

6. Find Industry reports, Company profiles
ReportLinker and Market Statistics
>> Get this Report Now by email!
Payment Information
Please indicate the payment method, you would like to use by selecting the appropriate box.
Payment by credit card Card Number: ______________________________________________
Expiry Date __________ / _________
CVV Number _____________________
Card Type (ex: Visa, Amex…) _________________________________
Payment by wire transfer Crédit Mutuel
RIB : 10278 07314 00020257701 89
BIC : CMCIFR2A
IBAN : FR76 1027 8073 1400 0202 5770 189
Payment by check UBIQUICK SAS
16 rue Grenette – 69002 LYON, FRANCE
Customer signature:
Please note that by ordering from Reportlinker you are agreeing to our Terms and Conditions at
http://www.reportlinker.com/index/terms
Please fax this form to:
Europe, Middle East and Africa : + 33 4 37 37 15 56
Asia, Oceania and America : + 1 (805) 617 17 93
Innovations in Molecular Diagnostics for Infectious Diseases (From Slideshare) Page 6/6