Created by Kirsten B. Haraldsen

2. Peter Agre Professor , MD, at Johns Hopkins University School of Medicine, Baltimore, MD, USA

3. Peter Agre Professor of Biological Chemistry and Professor of Medicine Johns Hopkins University School of Medicine, Baltimore, MD, USA Director of the Johns Hopkins Malaria Research Institute CHAIR of the The American Association for the Advancement of Science Nobel laureate in chemistry Honory doctor at the UiO Faculty of Medicine

4. Visiting North Korea, 2009, representing the US-DPRK Scientific Engagement Consortium

5. Peter Agre and Scientific diplomacy

6. The scientific diplomat CHAIR of the The American Association for the Advancement of Science: Dr. Peter C. Agre

7. A Conversation With Peter Agre Using a Leadership Role to Put a Human Face on Science By CLAUDIA DREIFUS Published: January 26, 2009

10. Publisert: 10.03.10 kl. 14:25 Nansen er forbilde…….

11. Fredsprisvinner Fridtjof Nansen fotografert på en russisk jernbane- stasjon i 1922 sammen med medlemmer av en russisk nødhjelpskomité. Nordmannen organiserte hjelp til flyktninger.

12. Scientific diplomacy

17. Worth watching! 

18. The talk is presented by Doris Jorde og Ole Petter Ottesen

19. Professor Ottersengraduated from the University of Oslo as Cand. med. (MD) in 1980, and gained his doctorate in medicine in 1982. He became professor of the Department of Anatomy in 1992.From 1997 to1999, Professor Ottersen was academic head of the Department of Anatomy; from 2000-2002 he was Vice-Dean of Research at the Medical Faculty, and from 2002 to 2009 he headed the Centre for Molecular Biology and Neuro- science – one of Norway’s centres of excellence. Professor Ottersen has received a num- ber of awards for his research, including the Anders Jahre Medical Prize for young scie- ntists in 1990 and the Anders Jahre Award for Medical Research (main award) in 2008. Professor Ottersen leads a broad-based team whose objective is to promote the quality of research and tuition at all faculties. The Rector and his team aim to develop the Uni- versity of Oslo into an internationally leading university with academic breadth centred around research. Ole Petter Ottersen Professor Ole PetterOttesen: Rector of the University of Oslo for the period 2009-2013

23. Doris Jorde Professor Doris Jorde: Vice-Rector of the University of Oslo for the period 2009-2013

26. Contact for the Academic Studies Administration

27. Leads the work on the action plan for internationalisation

29. scientific love: E=MC2.

30. ”Oursingle greatestdefenseagainstscientificignorance is education, and early in thelifeofevery scientist, thechild's first interestwassparked by a teacher.” Nobel Banquetspeech, 2003. “The need for general scientific understanding by the public has never been larger, and the penalty for scientific illiteracy never harsher… Lack of scientific fundamentals causes people to make foolish decisions about issues such as the toxicity of chemicals, the efficacy of medicines, the changes in the global climate.” Nobel Banquet speech, 2003.

32. The Nobel Prize in Chemistry 2003 was awarded "for discoveries concerning channels in cell membranes" jointly with one half to Peter Agre"for the discovery of water channels" and with one half to Roderick MacKinnon "for structural and mechanistic studies of ion channels". Roderick MacKinnon Peter Agre (left) and Roderick MacKinnon at the Nobel Prize Award Ceremony at the Stockholm Concert Hall, 10 December 2003.

33. Peter Agre and Aquaporins – Water channels Aquaporin1 channel (AQP1) from RCSB PBD (protein data bank)

34. WERE YOU SURPRISED TO WIN THE NOBEL PRIZE FOR THIS FINDING? There were some clues that this might happen. Like getting invited to Sweden to give lectures. But at 5:30 a.m. on an October morning, the phone rang. “Hello, Professor Agre, this is Stockholm. You have won the Nobel Prize in Chemistry. In about 10 minutes we’re having a press conference and the whole world will hear — so you’d better get on with your day.” I sprinted into the shower, and my wife, Mary, called my mother, who said, “That’s very nice, but don’t let it go to his head.” Agre lab on Oct. 8, 2003 Dad always raved that Pauling's accomplishments were the greatest, and he instilled in us his view that the Nobel Prize is the closest thing to the Holy Grail.

36. Appearanceof water channels in Xenopusoocytesexpressing red cell CHIP28 protein by G.M. Preston, T.P. Carroll, W.B. Guggino, and P. Agre, Science 256 (1992), p. 385-387 Agre, P (2008) Aquaporin water channels: From atomic structure to clinical medicine. NEUROSCIENCE RESEARCH 61, S2-S2 MolecularMechanisms for Human Diseases by P. Agre and D. Kozono, FEBS Lett. 555 (2003), p. 72-78 Carbrey, JM; Song, LH; Zhou, Y; Yoshinaga, M; Rojek, A; Wang, Y; Liu, Y; Lujan, H; DiCarlo, S; Nielsen, S; Rosen, B; Agre, P; Mukhopadhyay, R (2009) Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. Proc. Nat. Acad. Sci. 106:37,15956-15960

37. Onlythosecellsthatcontainaquaporincanabsorb water and swellup.

38. Recentpublications: Agre, P (2011) Life on the River of Science. SCIENCE 331: 6016, 416-421 Agre, P (2010) The family naturalist. NATURE 467: 7317, S11-S11 Agre, P; Leshner, AI (2010) Bridging Science and Society. SCIENCE 327:5968, 921-921 Cyranoski, D; Agre, P (2010) The scientific diplomat. NATURE 463:7279, 281-281 Carbrey, JM; Song, LH; Zhou, Y; Yoshinaga, M; Rojek, A; Wang, Y; Liu, Y; Lujan, H; DiCarlo, S; Nielsen, S; Rosen, B; Agre, P; Mukhopadhyay, R (2009) Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. Proc. Nat. Acad. Sci. 106:37,15956-15960 Rabaud, NE; Song, L; Wang, Y; Agre, P; Yasui, M; Carbrey, J (2009) Aquaporin 6 binds calmodulin in a calcium-dependent manner. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 383:1, 54-57 Liu, YJ; Song, LH; Wang, YD; Rojek, A; Nielsen, S; Agre, P; Carbrey, J(2009) Osteoclastdifferentiation and function in aquaglyceroporin AQP9-null mice. BIOLOGY OF THE CELL 101:3, 133-140 Josephsen, K; Praetorius, J; Frische, S; Gawenis, L; Kwon, T; Agre, P; Nielsen, S; Fejerskov, O (2009) Targeted disruption of the Cl-/HCO3- exchanger Ae2 results in osteopetrosis in mice. Proc. Nat. Acad. Sci. 106:5, 1638-1641 Agre, P (2008) Aquaporin water channels: From atomic structure to clinical medicine. NEUROSCIENCE RESEARCH 61, S2-S2 Agre, P; Kurzweil, R; Nestle, M; Chapman, M; Rubin, H; Chivian, E; Moreno, J; Mooney, C; Davies, P; Grego, L; Carroll, S (2008) Please Mr President, do one thing for me. NEW SCIENTIST 200:2676, 18-19

39. Peter Agre Honorydoctor at the UiO FacultyofMedicine

40. 07.09.2004

41. 01.02.2004

43. Jacobsen, Øyvind; Maekawa, Hiroaki; Ge, Nien-Hui; Gorbitz, Carl Henrik; Rongved, Pål; Ottersen, Ole Petter; Mahmood reza, Amiry-Moghaddam et al. (2011). Stapling of a 310-Helix withClickChemistry. Journal ofSyntheticOrganicChemistry, Japan. ISSN 0037-9980. . doi: 10.1021/jo101670a Biological Sciences - Neuroscience: Alexander S. Thrane, Phillip M. Rappold, TakumiFujita, Arnulfo Torres, Lane K. Bekar, TakahiroTakano, WeiguoPeng, Fushun Wang, VinitaRangrooThrane, Rune Enger, Nadia N. Haj-Yasein, Øivind Skare, Torgeir Holen, Arne Klungland, Ole P. Ottersen, Maiken Nedergaard, and Erlend A. Nagelhus Criticalroleof aquaporin-4 (AQP4) in astrocytic Ca2+signaling eventselicited by cerebral edema PNAS 2011 108 (2) 846-851; publishedaheadofprint December 27, 2010, doi:10.1073/pnas.1015217108 OPEN ACCESS ARTICLE

47. Peter Agre and WATER Crystal structureofthe AQP1 water channel

48. George Tombs: Before getting to malaria, let’s talk first about water and aquaporins. Could you tell me why you’ve said in one of your writings that water is the solvent of life? …………………. George: Whether as a scientist or an outdoorsman, you seem to be fascinated by water……….

52. nature. reviews Clarke and Peter Agre (Photos:PeterAgre) From: http://www.evidentia.net/

53. Water is life….. Dr. Peter Agre displays his Eagle Scout Award and his Nobel Prize for Chemistry medal. Photograph By Walter Calahan. Photo: Stephen J. Boitano/Getty Images Clarke and Peter Agre (Photos:PeterAgre) From: http://www.evidentia.net/

54. Peter Agre dances with his wife at the Nobel Banquet, 10 December 2003.Copyright © Photo: Ola Torkelsson Peter Agre has Scandinavianroots: “The Agres were Norwegian (Osterdalen and Trondelag), while the Swedbergs had mixed origins - Swedish (Skåne) and Norwegian (Telemark)”.

55. Science 28.Januar 2011 (…KBH’s bursdag! …)

57. Peter Agre and Public health

59. Peter Agre and his books

60. Bøkene hans: Protein Blood Group Antigens of the Human Red Cell: Structure, Function, and Clinical Significance (The Johns Hopkins Series in Hematology/Oncology) By: Peter C. Agre (Author) and Jean-Pierre Cartron (Editor) Johns Hopkins University Press 1992 CurrentTopics in Membranes, 2001 Hematology 1989

61. heidddddi

62. Bøkene hans: Protein Blood Group Antigens of the Human Red Cell: Structure, Function, and Clinical Significance (The Johns Hopkins Series in Hematology/Oncology) By: Peter C. Agre (Author) and Jean-Pierre Cartron (Editor) Johns Hopkins University Press 1992 CurrentTopics in Membranes, 2001 Hematology 1989

66. Science Debate- Events in Vilhelm Bjerknes’ hus, fall 2010:

69. Marcus du Sautoy and The Public Understandingof Science Aboutsymmetry Science Debate- Events in Vilhelm Bjerknes’ hus fall 2010:

71. Science Debate- Events in Vilhelm Bjerknes’ hus, fall 2010:

74. Science Debate- Events in Vilhelm Bjerknes’ hus, fall 21010: Kjør debatt ledet av Kåre Verpe

76. BioinformaticsUsers Forum 2010 12. November in Vilhelm Bjerknes’hus MLSUiO Det Nye Realfagsbiblioteket i Vilhelm Bjerknes’ hus og Science debate i Norge i samarbeid med Fritt Ord

77. Science Debate- Events in Vilhelm Bjerknes’ hus, fall 2010: Center for MolecularBiology and Neuroscience (CMBN) Bioinformatics Group og deres samarbeidsprosjekter, om kjernefasilitetet for bioinformatikk, om EMBnetNorway, om PubGene og mye annet på BioinformaticsUser Forum 2010.

79. Science Debate- Events in Vilhelm Bjerknes’ hus, fall 2010:

80. Science Debate- Events in Vilhelm Bjerknes’ hus , fall 2010:

81. Syntetisk biologi - Skrekkblandet fryd Debatten… Med Sissel Rogne Inger Sandlie Erik Tunstad Ill.: Harry Campbell/ieeespectrum

82. about….. The BioBricks Foundation and iGEM

83. iGEM 2010 Photo: iGEM/Justin Knight

87. (~3,000 species, based on rRNA sequences) Vi er her! Please cite the source as: David M. Hillis, Derrick Zwickl, and Robin Gutell, University of Texas (seeScience, 2003, 300:1692-1697)

89. Det nye Realfagsbiblioteket The new Science Library in Vilhelm Bjerknes’ hus and Science Debate in Norway , supported by Fritt Ord

90. VILHELM BJERKNES’ HUSThe new Science Library(Realfagsbiblioteket) Get Real Commitment to Science for students and employees at University of Oslo

91. – et sted å legge grunnlag for ny forskning, fortsette læringen, bli inspirert, møte venner, kollegaer og foreleser.

92. Who? The norwegian scientist Vilhelm Bjerknes (1862-1951) is regarded as oneofthefoundersofmeteorology. He wasalso a prominent scientist in physics and geophysics.

93. On Facebook Det Nye Realfagsbiblioteket also in 2011 The New Science Library in Vilhelm Bjerknes’ hus and Science debate in Norway- a cooperationwith Fritt Ord

95. Ny fb side her del forrige

97. Aquaporins and water channels Literature …. ………..something to read om coldwinterdays…

98. elektronisk

100. Aquaproteins and water – books to readcontinued….

101. From 1990 – Preaquaporinium ;-) elektronisk

105. ” There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved.”