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Peter Agre trailer

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  • Jenter og realfag
  • Attraktiv arena for studier innen realfag – ny storstue og arena for formidling av UiOs forskning
  • facebooksiden
  • Transcript

    • 1.
    • 2. Peter Agre
      Professor , MD, at Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • 3. Peter Agre
      Professor of Biological Chemistry and Professor of Medicine
      Johns Hopkins University School of Medicine, Baltimore, MD, USA
      Director of the Johns Hopkins Malaria Research Institute
      CHAIR of the The American Association for the Advancement of Science
      Nobel laureate
      in chemistry
      Honory doctor at the UiO Faculty of Medicine
    • 4. Visiting North Korea, 2009, representing the US-DPRK Scientific Engagement Consortium
    • 5. Peter Agre
      and
      Scientific diplomacy
    • 6. The scientific diplomat
      CHAIR of the The American Association for the Advancement of Science:
      Dr. Peter C. Agre
    • 7. A Conversation With Peter Agre
      Using a Leadership Role to Put a Human Face on Science
      By CLAUDIA DREIFUS
      Published: January 26, 2009
    • 8.
    • 9.
    • 10. Publisert: 10.03.10 kl. 14:25
      Nansen er forbilde…….
    • 11. Fredsprisvinner
      Fridtjof Nansen fotografert
      på en russisk jernbane-
      stasjon i 1922 sammen med
      medlemmer av en russisk
      nødhjelpskomité.
      Nordmannen organiserte
      hjelp til flyktninger.
    • 12. Scientific diplomacy
    • 13.
    • 14.
    • 15.
    • 16.
    • 17. Worth watching! 
    • 18. The talk is presented by
      Doris Jorde og Ole Petter Ottesen
    • 19. Professor Ottersengraduated from the University of Oslo as Cand. med. (MD) in 1980,
      and gained his doctorate in medicine in 1982. He became professor of the Department
      of Anatomy in 1992.From 1997 to1999, Professor Ottersen was academic head of the
      Department of Anatomy; from 2000-2002 he was Vice-Dean of Research at the Medical
      Faculty, and from 2002 to 2009 he headed the Centre for Molecular Biology and Neuro-
      science – one of Norway’s centres of excellence. Professor Ottersen has received a num-
      ber of awards for his research, including the Anders Jahre Medical Prize for young scie-
      ntists in 1990 and the Anders Jahre Award for Medical Research (main award) in 2008.
      Professor Ottersen leads a broad-based team whose objective is to promote the quality
      of research and tuition at all faculties. The Rector and his team aim to develop the Uni-
      versity of Oslo into an internationally leading university with academic breadth centred
      around research. 
      Ole Petter Ottersen
      Professor Ole PetterOttesen: Rector of the University of Oslo for the period 2009-2013
    • 20.
    • 21.
    • 22.
    • 23. Doris Jorde
      Professor Doris Jorde: Vice-Rector of the University of Oslo for the period 2009-2013
    • 24.
    • 25. Doris Jorde
      Professor Doris Jorde has been appointed Vice-Rector of the University of Oslo for the period 2009-2013 by the Rector.
      Doris Jorde obtained a Master of Science degree at the University of California, Berkeley, in 1980, and a PhD in Science Education at the same university in 1984. Since 1984, Professor Jorde has been with the University of Oslo’s Department of Teacher Education and School Development. She also heads the “Rrid-skolen” project (Teaching Scientific Inquiry), and is project manager for the EU project “Mind the Gap”.
      In 2005 Professor Jorde received the Communication Award at the University of Oslo.
      Areas of Responsibility:
      • Leads the Study Committee
      • 26. Contact for the Academic Studies Administration
      • 27. Leads the work on the action plan for internationalisation
      • 28. Responsible for following up teacher training and e-learning
    • Peter Agre
      and
      The Nobel Prize
      Peter Agre receiving his Nobel Prize from His Majesty King Carl XVI Gustaf of Sweden at the Stockholm Concert Hall, 10 December 2003.
    • 29. scientific love: E=MC2.
    • 30. ”Oursingle greatestdefenseagainstscientificignorance
      is education, and early in thelifeofevery scientist,
      thechild's first interestwassparked by a teacher.”   
      Nobel Banquetspeech, 2003.
      “The need for general scientific understanding
      by the public has never been larger, and the penalty for
      scientific illiteracy never harsher…
      Lack of scientific fundamentals causes people to make
      foolish decisions about issues such as the toxicity of chemicals,
      the efficacy of medicines, the changes in the global climate.”
      Nobel Banquet speech, 2003.
    • 31.
    • 32. The Nobel Prize in Chemistry 2003 was awarded "for discoveries concerning channels in cell membranes" jointly with one half to Peter Agre"for the discovery of water channels" and with one half to Roderick MacKinnon "for structural and mechanistic studies of ion channels".
      Roderick MacKinnon
      Peter Agre (left) and Roderick MacKinnon at the Nobel Prize Award Ceremony at the Stockholm Concert Hall, 10 December 2003.
    • 33. Peter Agre
      and
      Aquaporins –
      Water channels
      Aquaporin1 channel (AQP1) from RCSB PBD (protein data bank)
    • 34. WERE YOU SURPRISED TO WIN THE NOBEL PRIZE FOR THIS FINDING?
      There were some clues that this might happen. Like getting invited to Sweden
      to give lectures. But at 5:30 a.m. on an October morning, the phone rang.
      “Hello, Professor Agre, this is Stockholm. You have won the Nobel Prize
      in Chemistry. In about 10 minutes we’re having a press conference and the whole
      world will hear — so you’d better get on with your day.”
      I sprinted into the shower, and my wife, Mary, called my mother, who said,
      “That’s very nice, but don’t let it go to his head.”
      Agre lab on Oct. 8, 2003
      Dad always raved that Pauling's accomplishments were the greatest, and he
      instilled in us his view that the Nobel Prize is the closest thing to the Holy Grail.
    • 35.
    • 36. Appearanceof water channels in Xenopusoocytesexpressing red cell CHIP28 protein by G.M. Preston, T.P. Carroll, W.B. Guggino, and P. Agre, Science 256 (1992), p. 385-387
      Agre, P (2008) Aquaporin water channels: From atomic structure to clinical medicine. NEUROSCIENCE RESEARCH 61, S2-S2
      MolecularMechanisms for Human Diseases by P. Agre and D. Kozono, FEBS Lett. 555 (2003), p. 72-78
      Carbrey, JM; Song, LH; Zhou, Y; Yoshinaga, M; Rojek, A; Wang, Y; Liu, Y; Lujan, H; DiCarlo, S; Nielsen, S; Rosen, B; Agre, P; Mukhopadhyay, R (2009) Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. Proc. Nat. Acad. Sci. 106:37,15956-15960
    • 37. Onlythosecellsthatcontainaquaporincanabsorb water and swellup.
    • 38. Recentpublications:
      Agre, P (2011) Life on the River of Science. SCIENCE 331: 6016, 416-421
      Agre, P (2010) The family naturalist. NATURE 467: 7317, S11-S11
      Agre, P; Leshner, AI (2010) Bridging Science and Society. SCIENCE 327:5968, 921-921
      Cyranoski, D; Agre, P (2010) The scientific diplomat. NATURE 463:7279, 281-281
      Carbrey, JM; Song, LH; Zhou, Y; Yoshinaga, M; Rojek, A; Wang, Y; Liu, Y; Lujan, H; DiCarlo, S; Nielsen, S; Rosen, B; Agre, P; Mukhopadhyay, R (2009) Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. Proc. Nat. Acad. Sci. 106:37,15956-15960
      Rabaud, NE; Song, L; Wang, Y; Agre, P; Yasui, M; Carbrey, J (2009) Aquaporin 6 binds calmodulin in a calcium-dependent manner. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 383:1, 54-57
      Liu, YJ; Song, LH; Wang, YD; Rojek, A; Nielsen, S; Agre, P; Carbrey, J(2009) Osteoclastdifferentiation and function in aquaglyceroporin AQP9-null mice. BIOLOGY OF THE CELL 101:3, 133-140
      Josephsen, K; Praetorius, J; Frische, S; Gawenis, L; Kwon, T; Agre, P; Nielsen, S; Fejerskov, O (2009) Targeted disruption of the Cl-/HCO3- exchanger Ae2 results in osteopetrosis in mice. Proc. Nat. Acad. Sci. 106:5, 1638-1641
      Agre, P (2008) Aquaporin water channels: From atomic structure to clinical medicine. NEUROSCIENCE RESEARCH 61, S2-S2
      Agre, P; Kurzweil, R; Nestle, M; Chapman, M; Rubin, H; Chivian, E; Moreno, J; Mooney, C; Davies, P; Grego, L; Carroll, S (2008) Please Mr President, do one thing for me. NEW SCIENTIST 200:2676, 18-19
    • 39. Peter Agre
      Honorydoctor at the UiO FacultyofMedicine
    • 40. 07.09.2004
    • 41. 01.02.2004
    • 42.
    • 43. Jacobsen, Øyvind; Maekawa, Hiroaki; Ge, Nien-Hui; Gorbitz, Carl Henrik; Rongved, Pål; Ottersen, Ole Petter; Mahmood reza, Amiry-Moghaddam et al. (2011).
       Stapling of a 310-Helix withClickChemistry.
      Journal ofSyntheticOrganicChemistry, Japan.  ISSN 0037-9980. . doi: 10.1021/jo101670a
      Biological Sciences - Neuroscience:
      Alexander S. Thrane, Phillip M. Rappold,
      TakumiFujita, Arnulfo Torres, Lane K. Bekar, TakahiroTakano, WeiguoPeng,
      Fushun Wang, VinitaRangrooThrane, Rune Enger, Nadia N. Haj-Yasein,
      Øivind Skare, Torgeir Holen, Arne Klungland, Ole P. Ottersen, Maiken Nedergaard,
      and Erlend A. Nagelhus
      Criticalroleof aquaporin-4 (AQP4) in astrocytic Ca2+signaling
      eventselicited by cerebral edema
      PNAS 2011 108 (2) 846-851; publishedaheadofprint
      December 27, 2010, doi:10.1073/pnas.1015217108
      OPEN ACCESS ARTICLE
    • 44.
    • 45.
    • 46.
    • 47. Peter Agre
      and
      WATER
      Crystal structureofthe AQP1 water channel
    • 48. George Tombs: Before getting to malaria,
      let’s talk first about water and aquaporins.
      Could you tell me why you’ve said in one
      of your writings that water is the solvent of life?
      ………………….
      George: Whether as a scientist or an outdoorsman, you seem to be fascinated by water……….
    • 49.
    • 50.
    • 51.
    • 52. nature. reviews
      Clarke and Peter Agre (Photos:PeterAgre)
      From: http://www.evidentia.net/
    • 53. Water is life…..
      Dr. Peter Agre displays his Eagle Scout Award and his Nobel Prize for Chemistry medal. Photograph By Walter Calahan.
      Photo: Stephen J. Boitano/Getty Images
      Clarke and Peter Agre (Photos:PeterAgre)
      From: http://www.evidentia.net/
    • 54. Peter Agre dances with his wife
      at the Nobel Banquet,
      10 December 2003.Copyright © Photo: Ola Torkelsson
      Peter Agre
      has Scandinavianroots:
      “The Agres were Norwegian (Osterdalen and Trondelag), while the Swedbergs had mixed origins - Swedish (Skåne) and Norwegian (Telemark)”.
    • 55. Science 28.Januar 2011
      (…KBH’s bursdag! …)
    • 56.
    • 57. Peter Agre
      and
      Public health
    • 58.
    • 59. Peter Agre and his books
    • 60. Bøkene hans:
      Protein Blood Group Antigens of the Human Red Cell: Structure, Function, and Clinical Significance
      (The Johns Hopkins Series in Hematology/Oncology)
      By: Peter C. Agre (Author) and Jean-Pierre Cartron (Editor)
      Johns Hopkins University Press 1992
      CurrentTopics in Membranes, 2001
      Hematology
      1989
    • 61. heidddddi
    • 62. Bøkene hans:
      Protein Blood Group Antigens of the Human Red Cell: Structure, Function, and Clinical Significance
      (The Johns Hopkins Series in Hematology/Oncology)
      By: Peter C. Agre (Author) and Jean-Pierre Cartron (Editor)
      Johns Hopkins University Press 1992
      CurrentTopics in Membranes, 2001
      Hematology
      1989
    • 63.
    • 64.
    • 65.
    • 66. Science Debate-
      Events in Vilhelm Bjerknes’ hus, fall 2010:
    • 67. 6. oktober kl. 05:40 · Kommenter · Liker
      •                                                                            
      Det nye realfagsbiblioteket i Vilhelm Bjerknes' husBill Bryson sitt foredrag fra 6.september finner du her http://realfagsbiblioteket.exss.no/usr/single.aspx?sid=19
      6. oktober kl. 04:42 · Kommenter · Liker · Vis tilbakemeldinger (1)Skjul tilbakemelding (1)
      • Anne Vedø liker dette.
      Science Debate-
      Events in Vilhelm Bjerknes’ hus , fall 2010:
      Det nye realfagsbiblioteket i Vilhelm Bjerknes' husBill Brysonsitt foredrag fra 6.september finner du her http://realfagsbiblioteket.exss.no/usr/single.aspx?sid=19
    • 68.
    • 69. Marcus du Sautoy
      and
      The Public Understandingof Science
      Aboutsymmetry
      Science Debate-
      Events in Vilhelm Bjerknes’ hus fall 2010:
    • 70.
    • 71. Science Debate-
      Events in Vilhelm Bjerknes’ hus, fall 2010:
    • 72.
    • 73.
    • 74. Science Debate-
      Events in Vilhelm Bjerknes’ hus, fall 21010:
      Kjør debatt ledet
      av Kåre Verpe
    • 75.
    • 76. BioinformaticsUsers Forum 2010
      12. November in Vilhelm Bjerknes’hus
      MLSUiO
      Det Nye Realfagsbiblioteket i Vilhelm Bjerknes’ hus og Science debate i Norge i samarbeid med Fritt Ord
    • 77. Science Debate-
      Events in Vilhelm Bjerknes’ hus, fall 2010:
      Center for MolecularBiology and Neuroscience (CMBN) Bioinformatics Group og deres samarbeidsprosjekter,
      om kjernefasilitetet for bioinformatikk, om EMBnetNorway, om PubGene og mye annet på BioinformaticsUser Forum 2010.
    • 78.
    • 79. Science Debate-
      Events in Vilhelm Bjerknes’ hus, fall 2010:
    • 80. Science Debate-
      Events in Vilhelm Bjerknes’ hus , fall 2010:
    • 81. Syntetisk biologi -
      Skrekkblandet fryd
      Debatten…
      Med
      Sissel Rogne
      Inger Sandlie
      Erik Tunstad
      Ill.: Harry Campbell/ieeespectrum
    • 82. about…..
      The BioBricks Foundation and iGEM
    • 83. iGEM 2010
      Photo: iGEM/Justin Knight
    • 84.
    • 85.
    • 86.
    • 87. (~3,000 species, based on rRNA sequences)
      Vi er her!
      Please cite the source as:
      David M. Hillis, Derrick Zwickl, and Robin Gutell, University of Texas
      (seeScience, 2003, 300:1692-1697)
    • 88.
    • 89. Det nye Realfagsbiblioteket
      The new Science Library
      in Vilhelm Bjerknes’ hus
      and
      Science Debate in Norway ,
      supported by Fritt Ord
    • 90. VILHELM BJERKNES’ HUSThe new Science Library(Realfagsbiblioteket)
      Get Real
      Commitment to Science
      for students and employees at
      University of Oslo
    • 91. – et sted å legge grunnlag for ny forskning, fortsette læringen, bli inspirert, møte venner, kollegaer og foreleser.
    • 92. Who?
      The norwegian scientist Vilhelm Bjerknes (1862-1951) is regarded as oneofthefoundersofmeteorology.
      He wasalso a prominent scientist in physics and geophysics.
    • 93. On Facebook
      Det Nye Realfagsbiblioteket also in 2011
      The New Science Library in Vilhelm Bjerknes’ hus
      and
      Science debate in Norway- a cooperationwith Fritt Ord
    • 94.
    • 95. Ny fb side her del forrige
    • 96.
    • 97. Aquaporins and water channels
      Literature ….
      ………..something to read om coldwinterdays…
    • 98. elektronisk
    • 99.
    • 100. Aquaproteins and water –
      books to readcontinued….
    • 101. From 1990 – Preaquaporinium ;-)
      elektronisk
    • 102.
    • 103.
    • 104.
    • 105. ” There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved.”