Some definitions:

Genome: the total genetic content
of an organism
Genomes have integrity when all their genes
function c...
consists
Genomic integrity
Each of us carries a ‘patchwork’ of many mutations in our DNA!
Some give us our father’s eyes or our gra...
Genomic integrity
The protection of genomic integrity
is therefore more readily facilitated
by preventing pollution of the...
Genomic integrity
Genomic integrity
Genomic integrity
Action for Genomic integrity through Research
AGiR

Research

Association
Communication

Information

To provide informati...
Aims of AGiR
To spread information &

pursue targeted research!
Aims of AGiR (2 years)
To spread information &
To increase by 30% public awareness of genomic integrity and risks for it.
...
Introducing AGiR: Action for Genomic integrity through Research
Introducing AGiR: Action for Genomic integrity through Research
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Introducing AGiR: Action for Genomic integrity through Research

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Action for genomic integrity
cigarettes, hair dye ingredients, UV light, all affect health in part due to effects on genomic integrity, our molecular heritage, so to speak. Our cells need saving and future generations need protection too. see more in the site!

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Introducing AGiR: Action for Genomic integrity through Research

  1. 1. Some definitions: Genome: the total genetic content of an organism Genomes have integrity when all their genes function correctly! Mutations are permanent changes in the genome. Research: systematic investigation to improve understanding.
  2. 2. consists
  3. 3. Genomic integrity Each of us carries a ‘patchwork’ of many mutations in our DNA! Some give us our father’s eyes or our grandmother’s smile. As long as the cells function correctly, all is ok! When something goes wrong, a possible cause is the loss of genomic integrity (i.e. copy number variations, deletions, mutations) Damage to nucleic acids, RNA included, can have grave consequences. Repair is crucial, but in many cases, such repair is quite error-prone, potentially leading to the generation of new mutations.
  4. 4. Genomic integrity The protection of genomic integrity is therefore more readily facilitated by preventing pollution of the environment by genotoxic substances.
  5. 5. Genomic integrity
  6. 6. Genomic integrity
  7. 7. Genomic integrity
  8. 8. Action for Genomic integrity through Research AGiR Research Association Communication Information To provide information and promote research
  9. 9. Aims of AGiR To spread information & pursue targeted research!
  10. 10. Aims of AGiR (2 years) To spread information & To increase by 30% public awareness of genomic integrity and risks for it. pursue targeted research! To identify quantitative and reliable measures of genomic integrity, robust enough to start a clinical study. Have a look! (& consider joining us!) https://sites.google.com/site/agiraction4genomicintegrity/

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