years old 2.5
BSAB 21%
Involving back, upper
buttock rt-arm both loin
, area
Scald injury hot milk
& All vital signs
investigations done with ideal
results
She is doing very well with this large
healthy burnd wound
Slow
healing
but
looks
healthy
Pt doing
good
SYSTEMIC SKIN ERRUPTION
ARE SET TO START
EPIDERMALEXFOLATION
OF EAR SKIN & CHEEKS

SCALP LESION
CRUSTATION+
Human GVHD occur after allogenic 
,stem cell transplantation
Acute GVHD describes a distinctive 
syndrome of Dermatitis,...
EXCISION – RE
AUTO GRAFTING
Who agree with



Who agree with SYSTIMIC STEROID
TREATMENT IF STARTED Auto -SKIN
GRAFTING AR...
Take biopsy from lesion & from unburned skin a
.maccule 2 cm distant area from the wound
The allograft are excised ,dressi...
DESQUAMATION & BULLAE
Clear face no skin lesion
dramatic response
Before
operation

days later 4
After
operation


Separation of epidermis from dermis (bullae like) (x4)
biopsy 2 cm distant from wound {at un burned skin}


Irregularity in rete ridges

(x4)
Separation of dermis from dermis with upper dermal
inflammation (x10)
)


Upper dermal lymphocytic infiltration (x40) path gnomonic
sign of AGVHD in the Skin
Auto split thickness
Skin-Graft done
2013 5 11

2013 6 18

Thank you
Dr.qutaiba abdulah aldori
Azadi Hospital kerkuk Iraq
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
Acute graft versus host disease by  dr. qutaiba abdulah
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Acute graft versus host disease by dr. qutaiba abdulah

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Acute graft versus host disease by dr. qutaiba abdulah

  1. 1. years old 2.5 BSAB 21% Involving back, upper buttock rt-arm both loin , area Scald injury hot milk
  2. 2. & All vital signs investigations done with ideal results
  3. 3. She is doing very well with this large healthy burnd wound
  4. 4. Slow healing but looks healthy Pt doing good
  5. 5. SYSTEMIC SKIN ERRUPTION ARE SET TO START
  6. 6. EPIDERMALEXFOLATION OF EAR SKIN & CHEEKS SCALP LESION CRUSTATION+
  7. 7. Human GVHD occur after allogenic  ,stem cell transplantation Acute GVHD describes a distinctive  syndrome of Dermatitis,Hepatits,& Enteritis developing within 100 days of allogenic hematopoietic cell transplantation Chronic GVHD describes a more  diverse syndrome developing after day 100
  8. 8. EXCISION – RE AUTO GRAFTING Who agree with  Who agree with SYSTIMIC STEROID TREATMENT IF STARTED Auto -SKIN GRAFTING ARE CONTRAINDICATED 
  9. 9. Take biopsy from lesion & from unburned skin a .maccule 2 cm distant area from the wound The allograft are excised ,dressing by sofratule  mesh gauze and povidon iodin impregnated gauze . bandaging 
  10. 10. DESQUAMATION & BULLAE
  11. 11. Clear face no skin lesion dramatic response
  12. 12. Before operation days later 4 After operation
  13. 13.  Separation of epidermis from dermis (bullae like) (x4) biopsy 2 cm distant from wound {at un burned skin}
  14. 14.  Irregularity in rete ridges (x4)
  15. 15. Separation of dermis from dermis with upper dermal inflammation (x10) )
  16. 16.  Upper dermal lymphocytic infiltration (x40) path gnomonic sign of AGVHD in the Skin
  17. 17. Auto split thickness Skin-Graft done
  18. 18. 2013 5 11 2013 6 18 Thank you Dr.qutaiba abdulah aldori Azadi Hospital kerkuk Iraq

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