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External Application of Essential Oils in Animals

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External Application of Essential Oils in Animals External Application of Essential Oils in Animals Presentation Transcript

  • External Application of Essential Oils in Animals Jürgen Reichling Institute of Pharmacy and Molecular Biotechnology, Department of Biology, University of Heidelberg Matricaria recutita Beautifulboy Mentha x piperita Rosmarinus officinalis Thymus vulgaris
  • Outline
    • Phytotherapeutical use of essential oils in animals
    • Antifungal effect of tea tree oil (TTO) on Malassezia pachydermatis isolated from canines suffering from cutaneous disease
    • Topical use of a 10% TTO-containing cream against canine localized pruritic dermatitis
    • Species specific differences and toxicolo-gical aspects
    • Conclusion
  • Phytotherapeutical use of essential oils in animals
    • Wounds and other problems of the skin
    • Respiratory ailments
    • Nervous system disorders
    • Ailments affecting the loco motor apparatus like rheumatism and arthritis
    • Repellents and antiparasitics
    • Antimicrobials and antibiotics
    • Digestion system and diarrhea
    • Control of pet odor
  • Phytotherapeutical use of selected essential oils in animals Wounds, inflammations, cuts, insect repellent, flea treatment Eucalyptus oil Eucalyptus globulus Wormer Absinthe oil Artemisia absinthium Bacterial infections, flea treatment Pennyroyal oil Mentha pulegium Flea treatment, insect repellant, dermatitis Tea trea oil Melaleuca alternifolia Wounds, burns, itching, dermatitis, inflamed skin German chamo-mile oil Matricaria recutita Otitis, gastritis, cuts, wounds, inflamed skin, dermatitis Pot marigolds Calendula officinalis USE ESSENTIAL OIL PLANT
  • Phytotherapeutical use of selected essential oils in animals Insect repellent, fungal infection Lemongras oil Cymbopogon citratus Wounds, ear and teeth care, repellent for fleas and ticks Myrrh oil Commiphora myrrha Paw cuts, dermatitis, irritated skin, wounds Helichrysum oil Helichrysum italicum Eczema, bacterial infections Thyme oil Thymus vulgaris Paw cuts, dermatitis, itching, insect repellent Lavender oil Lavandula angustifolia Insect repellent, itching Geranium oil Pelargonium roseum USE ESSENTIAL OIL PLANT
  • Treatment of fleas
    • For treatment of flea infested animals an USA patent propagates a mixture of pennyroyal oil, eucalyptus oil, cedar oil, citronella oil and rue oil inserted into apricot kernel oil, olive oil or almond oil in concentrations up to 7%.
    • In the market you will find different essential oil-containing preparations, such as herbal flea shampoos, herbal flea collars or herbal flea drops for dogs
  • Acaricidal effect of Tea Trea Oil (TTO)
    • In an in vitro experiment the acaricidal effect of TTO on nymphs of Ixodes ricinus was examined. It was found that 8 to 10 µl of TTO was lethal for more than 80% of the ticks when TTO was inhaled.
    • The acaricidal effect correlated very well with the duration of exposure of ticks to TTO.
  • Parasitic mite infection control in honeybee colonies V Rosemary oil V Oregano oil V Eucalyptus oil V and T Thyme oil V and T Lemongras oil V and T Lemon oil Mites: Varroa destructor (V) and Acarapis woodi (T) Selected essential oils
  • Malassezia pachydermatis
  • Dog paw of a Labrador Retriever infected by Malassezia pachdermatis
  • Antifungal effect of Tea Trea Oil (TTO) on Malassezia pachydermatis isolated from canines suffering from cutaneous disease 0.8 1120.0 B 7148 0.4 1120.0 B 7139 0.4 – 0.8 1120.0 B 7124 0.8 560.0 B 7104 0.8 – 1.6 1120.0 B 7097 MFC of Terb.-HCL [µg/ml] MFC of TTO [µg/ml] Clinical isolates
  • Antibacterial activity of Tea Tree Oil (TTO) against different Staphylococcus species MIC [µg/ml] Staphylococcus species 2500 – 5000 Staphylococcus haemolyticus 2500 Staphylococcus xylosus 2500 -5000 Staphylococcus saprophyticus 1200 Staphylococcus hominis 2500 – 5000 Staphylococcus epidermidis 1200 – 2500 Staphylococcus capitis 2500 Staphylococcus aureus
  • Topical use of a 10% TTO-containing cream against canine localised pruritic dermatitis
  • Topical use of a 10% TTO-containing cream against canine localised pruritic dermatitis
  • Species specific differences and toxicological aspects
    • 1. Dogs can utilize carotinoids from plants to synthesize retinol, but cats require preformed Vitamin A from animal tissue.
    • 2. Dogs can use either fish or plant sources of omega-3-fatty acids, whereas cats require fish because they lack in delta-6-desaturase. Cats can synthesize neither eicosapentaenoic acid from α-linolenic acid nor arachidonic acid from linoleic acid.
  • Species specific differences and toxicological aspects
    • 3. Cats are highly sensitive to essential oils because they are lacking in glucuronyl transferase activity.
    • 4. In most cases of reported adverse side effects, the essential oils were used to treat dermatological conditions at inap-propriate high doses.
  • Species specific differences and toxicological aspects
    • 5. The most common clinical signs after dermal exposure of inappropriate high concentrations of essential oils include ataxia, muscle weakness, depression, and behavioral abnormalities.
    • 6. Some essential oils are phototoxic (e.g. bergamot oil) and can burn skin badly if exposed to sunlight.
  • Conclusion
    • Evidence-based veterinary phytotherapy is still in its infancy.
    • At present, the use of essential oils in animals is exclusively based on anec-dotal reports and experiences of aroma therapists and pet owners.
    • So called aroma therapists are mostly laymen and subsequently lacking in a medicinal background.
  • Conclusion
    • Our first clinical trial with TTO in dogs have shown that an evidence-based use of essential oil in animals is possible.
    • When using essential oils in animals species specific differences have to be taken into account.
    • Essential oils are powerful biological agents which should be used in appro-priate doses, indicated ailments, during a limited time period and with care.
  • Thank you for your attention