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acne.ppt Presentation Transcript

  • 1. Acne Vulgaris
  • 2. Acne Overview
    • Acne Vulgaris: “a chronic acne involving mainly the face, chest, and shoulders that is common in adolescent humans and various domestic animals and is characterized by the intermittent formation of discrete papular or pustular lesions often resulting in considerable scarring”
    • Common & Limited to the Skin
    • Effects prepubescent individuals, teenagers, & adults
    • Inflammatory lesions & scarring = social damage
    • Compliance is essential
  • 3. The Compliance Study
    • Examination with completion of questionnaire
    • Re-examined after 3 months
    • Derived the Objective Medication Adherence (Med Ad)
    • Discovered factors that influence compliance
    • Treatments include: topical, oral antibiotics, hormonal, & oral retinoid
  • 4. Measurement of Compliance
    • “Compliance with treatment regimen is an essential element in overall effectiveness of therapy”
    • Objective-examine how patients complied with the study
      • Important for patients to comply in order for the results to be accurate
  • 5. Measurement of Compliance cont.
    • Measure the amount of the prescribed drug in the patient
    • Testers have to be cautious of patient realizing what is being tested
    • In examining compliance: measured pill count, outcome of the process (DLQI) and clinic attendance
  • 6. Study Design
    • This study was an open, prospective study of 687 consecutive patients, all between the ages of 12 and 48.
    • The study included patients with different demographic features and with different degrees of severity of acne vulgaris.
    • Each patient was given a QOL assessment, which questioned the quality of the physical, emotional, social, and role-or-function-associated life situation of an individual (i.e. how badly each patient’s acne was affecting his/her emotional, physical, and social states).
      • The assessment contained 10 questions, with a score range from 0 to 3 per question.
  • 7. Patient Demographics
  • 8. Treatment Statistics 1 Zaghloul
  • 9. Inclusion Criteria
    • Male or female patients with a firm diagnosis of acne.
    • Able to give informed consent.
    • Each patient was prescribed an oral, topical, or combined treatment
  • 10. Topical and Oral Treatments
    • Topical Treatments:
      • The amount of topical treatment per patient was estimated by measuring the surface area of the face, using the Rule of Hand.
      • FTU’s (Fingertip Units) were calculated for each patient to manage their treatment application (for example, 1 FTU= 0.5g= 2% surface area)
    • Oral Treatments:
      • Tablets were prescribed by calculating the daily number of tablets prescribed divided by the number of days that the study lasted.
    • Each patient was directly asked questions about his/her treatment application/consumption. Each interview lasted for about 30-60 minutes.
  • 11. Work Cited
    • Zaghloul S.S., W.J Cunliffe and M.J.D. Goodfield. “Objective Assessment of Compliance with Treatments in Acne.” British Journal of Dermatology vol. 152 May 2005: 1015.