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1. Brash HM, McQueen DS, Christie D, Bell JK, Bond SM, Rees ... Document Transcript

  • 1. 1. Brash HM, McQueen DS, Christie D, Bell JK, Bond SM, Rees JL. A repetitive movement detector used for automatic monitoring and quantification of scratch in mice. Journal of Neuroscience Methods 2005;142(1):107-114. 2. Rees J, Murray CS. Itching for progress (in press). Clinical & Experimental Dermatology 2005. 3. Rees JL. Skin disease genetics. In: Hastie N, Wright A, editors. The genetics of common diseases (in press). Oxford: OUP, 2005. 4. Rees JL. DNA typing and colour of skin and hair. In: Morling N, editor. Handbook of Forensic Genetics: Humana, 2005. 5. Rees JL. Review of Itch: Basic mechanisms and therapy. ed by Yosipovitch, Greaves, Fleischer and McGlone (in press). Journal of the American Academy of Dermatology 2005. 6. Rees JL. Melanogenesis, skin colour, and sun exposure as cancer risk factors in Africa (in press). In: Ny A, editor. Geneva: WHO, 2005. 7. Wong TH, Rees JL. The relation between melanocortin 1 receptor (MC1R) variation and the generation of phenotypic diversity in the cutaneous response to ultraviolet radiation. Peptides 2005;in press. 8. Bell JK, McQueen DS, Rees JL. Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in BalbC mice. Br J Pharmacol 2004;142(2):374. 9. Benjamin K, Waterston K, Russell M, Schofield O, Diffey B, Rees JL. The development of an objective method for measuring scratch in children with atopic dermatitis suitable for clinical use. Journal of the American Academy of Dermatology 2004;501(1):33. 10. Bringhurst C, Waterston K, Schofield O, Benjamin K, Rees JL. Meaurement of itch using actigraphy in paediatric and adult populations. Journal of the American Academy of Dermatology 2004. 11. Manson C, Naysmith L, Waterston K, Melton DW, Rees JL. No association between p53 codon 72 polymorphisms and erythemal response. Journal of Investigative Dermatology 2004;122(5):1334. 12. Naysmith L, Waterston K, Ha T, Flanagan N, Bisset Y, Ray A, et al. Quantitative Measures of the Effect of the Melanocortin 1 Receptor on Human Pigmentary Status. Journal of Investigative Dermatology 2004;122(2):423. 13. Oh C, Hennessy A, Ha T, Bisset Y, Diffey B, Rees JL. The Time Course of Photoadaptation and Pigmentation Studied Using a Novel Method to Distinguish Pigmentation from Erythema. Journal of Investigative Dermatology 2004;123(5):965. 14. Rees J. In this issue: more genes for psoriasis. Journal of Investigative Dermatology 2004;123:vi. 15. Rees J. In this isuse: A little light risk. Acta Dermato-Venereologica 2004;84(5):338. 16. Rees J. The fundamentals of clinical discovery. Perspect.Biol.Med 2004;47(4):597. 17. Rees JL, Burns DA, Breathnach SM, Cox NH, Griffiths CE. Molecular Biology. Rook's Textbook of Dermatology. Oxford: Blackwell Publishing Limited, 2004:8.1.
  • 2. 18. Rees JL. The genetics of human pigmentation: the case of red hair. Current Medical Literature, 2004:29. 19. Rees JL. In this issue: Mathematical modelling and how phototherapy works. Acta Dermato- Venereologica 2004;84:257. 20. Rees JL. The genetics of sun sensitivity in humans. Am J Hum.Genet 2004;75(5):739. 21. Ringholm A, Klovins J, Rudzish R, Phillips S, Rees JL, Schioth HB. Pharmacological Characterization of Loss of Function Mutations of the Human Melanocortin 1 Receptor That Are Associated with Red Hair. Journal of Investigative Dermatology 2004;123(5):917. 22. Waterston K, Naysmith L, Rees JL. Physiological Variation in the Erythemal Response to Ultraviolet Radiation and Photoadaptation. Journal of Investigative Dermatology 2004;123(5):958. 23. Ha T, Waterston K, Bisset Y, Ray A, Rees JL. The time course of ultraviolet B induced erythema in people with red hair harbouring homozygous melanocortin 1 receptor (MC1R) mutations. Experimental Dermatology 2003;12(4):514. 24. Ha T, Naysmith L, Waterston K, Oh C, Weller R, Rees JL. Defining the Quantitative Contribution of the Melanocortin 1 Receptor (MC1R) to Variation in Pigmentary Phenotype. Annals of the New York Academy of Sciences 2003;994:339. 25. Ha T, Javedan H, Waterston K, Naysmith L, Rees JL. The relation between constitutive pigmentation and sensitivity to ultraviolet radiation induced erythema is dose dependant. Pigment Cell Research 2003;16:477. 26. McKenzie CA, Harding RM, Tomlinson JB, Ray AJ, Wakamatsu K, Rees JL. Phenotypic expression of melanocortin-1 receptor (MC1R) mutations in Black Jamaicans. Journal of Investigative Dermatology 2003;121(1):207. 27. Naysmith L, Rees JL. Psoriasis and its Management. Journal of the Royal College of Physicians Edinburgh 2003;33:104. 28. Rees J. P for Probability and p for p53. J Invest Dermatol 2003;121(6):XII. 29. Rees J. In this issue. J Invest Dermatol 2003;121(6):VI. 30. Rees JL. Trials, evidence and the management of patients with psoriasis. Journal of the American Academy of Dermatology 2003;48:135. 31. Rees JL, Cooper DN. Skin pigmentation: genetics. Encyclopedia of the Human Genome. London: Nature Publishing Group, 2003:326. 32. Rees JL. Genetics of Hair and skin colour. Annual Review of Genetics 2003;37:67. 33. Ha T, Rees JL. Red hair--a desirable mutation. Journal of Cosmetic Dermatology 2002;1:62. 34. Laidlaw A, Flecknell P, Rees JL. Production of acute and chronic itch with histamine and contact sensitisers in the mouse and guinea pig. Experimental Dermatology 2002;11(4):285.
  • 3. 35. Rees J. Two cultures? Journal of the American Academy of Dermatology 2002;46(2):313. 36. Rees J. Complex Disease and the New Clinical Sciences. Science 2002;296(5568):698. 37. Rees JL. What is the True Function of Skin? Experimental Dermatology 2002;11(2):187. 38. Rees JL, Newton-Bishop J, Gore M. Why are Redheads so Susceptible to Melanoma? Melanoma: Critical Debates. Oxford: Blackwell Science, 2002:49. 39. Rees JL. The Skin and Gene Therapy: review of 'The Skin and Gene Therapy', by UR Hengge and B Volc-Platzer, Spriner Verlag, Berlin 2000. Journal of Dermatological Treatment 2002;13:95. 40. Rees JL. Clinical Science: time for a new contract. Clinical Medicine 2002;2 (5):423. 41. Rees JL, Jean-Paul O, Robert B. Molecular Phototypes. Mechanisms of Suntanning. London: Martin Dunitz, 2002:333. 42. Rees JL, Vogelstein B, Kinzler K. Skin cancer (Including nevoid basal cell carcinoma syndrome). The genetic basis of human cancer. New York: McGraw-Hill, 2002:529. 43. Schofield OMV, Rees JL, Haslett C, Chilvers ER, Boon NA, Colledge NR, et al. Skin Disease. Davidson's Principles and Practice of Medicine. Edinburgh: Churchill Livingstone, 2002:1049. 44. Wakamatsu K, Ito S, Rees JL. Usefulness of 4-Amino-3-hydroxyphenylalanine as a specific marker of Pheomelanin. Pigment Cell Research 2002;15:225. 45. Flanagan N, Ray AJ, Todd C, Birch-Machin MA, Rees JL. The relation between melanocortin 1 receptor genotype and experimentally assessed ultraviolet radiation sensitivity. Journal of Investigative Dermatology 2001;117(5):1314. 46. Ha T, Rees J. Melanocortin 1 receptor: What's red got to do with it? Journal of the American Academy of Dermatology 2001;45(6):961. 47. Hatta N, Dixon C, Ray AJ, Phillips SR, Cunliffe WJ, Dale M, et al. Expression, candidate gene, and population studies of the melanocortin 5 receptor. Journal of Investigative Dermatology 2001;116(4):564. 48. Healy E, Jordan SA, Budd PS, Suffolk R, Rees JL, Jackson IJ. Functional variation of MC1R alleles from red-haired individuals. Human Molecular Genetics 2001;10(21):2397. 49. Rees JL, Scriver CR, Beaudet AL, Sly WS, Valle D, Childs B, et al. Skin cancer (including nevoid basal cell carcinoma syndrome). Metabolic and molecular bases of inherited disease. New York: McGraw-Hill, 2001:989. 50. Rees JL. Post genomics: so that is what they call clinical science. Clinical Medicine 2001;1(5):393. 51. Rees JL. Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment and Monitoring. Journal of Dermatological Treatment 2001;117:1331. 52. Rees JL, Ha T. In This Issue. Journal of Investigative Dermatology 2001;117:1333. 53. Velangi SS, Rees JL. Why are scars pale? An immunohistochemical study indicating preservation of
  • 4. melanocyte number and function in surgical scars. Acta Dermato-Venereologica 2001;81:326. 54. Flanagan N, Healy E, Ray A, Philips S, Todd C, Jackson IJ, et al. Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation. Human Molecular Genetics 2000;9(17):2531. 55. Ha T, Rees JL. Keeping genetics simple. Acta Dermato-Venereologica 2000;80 (6):401. 56. Harding RM, Healy E, Ray AJ, Ellis NS, Flanagan N, Todd C, et al. Evidence for variable selective pressures at the human pigmentation locus, MC1R. American Journal of Human Genetics 2000;66:1351. 57. Healy E, Flannagan N, Ray A, Todd C, Jackson IJ, Matthews JNS, et al. Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair. Lancet 2000;355(9209):1072. 58. Healy E, Birch-Machin MA, Rees JL, Cone RD. The Human Melanocortin-1 receptor. In: Byland DB, editor. The Melanocortin Receptors. New Jersey: Humana Press, 2000:341. 59. Ray AJ, Turner R, Nikaido O, Rees JL, Birch-Machin MA. The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin. Journal of Investigative Dermatology 2000;115(4):674. 60. Rees J. Evidence-based medicine: the epistemology that isn't. Journal of the American Academy of Dermatology 2000;43(4):727. 61. Rees J. Patents and intellectual property: a salvation for patient-orientated research? Lancet 2000;356:849. 62. Rees J, Ha T. In this issue. Journal of Investigative Dermatology 2000;115:933. 63. Rees J. Review of Evolutionary Medicine eds Trevathen, R, SmithEO, and McKenna,JJ. OUP New York 1999. Heredity 2000;84:733. 64. Rees JL. The melanocortin 1 receptor (MC1R): more than just red hair. Pigment Cell Research 2000;13(3):135. 65. Rees JL. Genetics, past and present, and the rise of systems dermatology. British Journal of Dermatology 2000;143(1):41. 66. Smith FJ, Fisher MP, Healy E, Rees JL, Bonifas JM, Epstein EH, Jr., et al. Novel keratin 16 mutations and protein expression studies in pachyonychia congenita type 1 and focal palmoplantar keratoderma. Experimental Dermatology 2000;9(3):170. 67. Wu YY, Rees JL. Variation in epidermal housekeeping gene expression in different pathological states. Acta Dermato-Venereologica 2000;80(1):2. 68. Wu YY, Takata M, Rehman I, Rees JL. The temporal and spatial distribution of p21 WAF expression in skin appendages. British Journal of Dermatology 2000;142(4):694. 69. Hegges UR, Taichman LB, Kaur P, Rogers G, Jensen TG, Goldsmith LA, et al. How realistic is cutaneous gene therapy? Experimental Dermatology 1999;8:419.
  • 5. 70. Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, et al. Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype. Journal of Investigative Dermatology 1999;113:607. 71. Korge BP, Healy E, Traupe H, Punter C, Mauch C, Hamm H, et al. Point mutation in the helix termination peptide (HTP) of human type II hair keratin hHb6 causes monilethrix in five families. Experimental Dermatology 1999;8(4):310. 72. Rees J. Understanding barrier function of the skin. Lancet 1999;354(9189):1491. 73. Rees JL, Flanagan N. Pigmentation, melanocortins and red hair. QJM - Monthly Journal of the Association of Physicians 1999;92(3):125. 74. Rees JL. The Importance of being red (Dowling Oration 1999). Clinical & Experimental Dermatology 1999;24:416. 75. Rees JL, Laidlaw A. Pruritus: more scratch than itch. Clinical & Experimental Dermatology 1999;24:490. 76. Rees JL, Birch-Machin M, Flanagan N, Healy E, Phillips S, Todd C. Genetic studies of the human melanocortin 1 receptor (MC1R). Annals of the New York Academy of Sciences 1999;885:134. 77. Rees JL. In this issue: PUVA the long burn. Journal of Investigative Dermatology 1999;113:292. 78. Ruiz-Perez V, Carter SA, Healy E, Todd C, Rees JL, Steijlen PM, et al. ATP2A2 mutations in Darier's disease:variant cutaneous phenotypes are associated with missense mutations, but neuropsychiatric feartures are independent of mutations class. Human Molecular Genetics 1999;8(9):1621. 79. Sakuntabhai A, Ruiz-Perez V, Carter S, Jacobsen N, Burge S, Monk S, et al. Mutations in ATP2A2, encoding a Ca 2+ pump, cause Darier disease. Nature Genetics 1999;21(3):271. 80. Schioth HB, Phillips S, Rudzish R, Birch-Machin M, Wikberg J, Rees JL. Loss of function mutations of the human melanocortin 1 receptor are common and associated with red hair. Biochemical & Biophysical Research Communications 1999;260:488. 81. Tabata H, Nagano T, Ray AJ, Flanagan N, Birch-Machin MA, Rees JL. Low frequency of genetic change in p53 immunopositive clones in human epidermis. Journal of Investigative Dermatology 1999;113(6):972. 82. Birch-Machin MA, Tindall M, Turner R, Haldane F, Rees JL. Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging. Journal of Investigative Dermatology 1998;110(2):149. 83. Healy E, Belgaid C, Takata M, Harrison D, Zhu NW, Burd DA, et al. Prognostic significance of allelic losses in primary melanoma. Oncogene 1998;16(17):2213. 84. Korge BP, Healy E, Munro CS, PÅnter C, Birch-Machin M, Holmes SC, et al. A mutational hotspot in the 2B domain of human hair basic keratin 6 (hHb6) in monilethrix patients. Journal of Investigative Dermatology 1998;111(5):896.
  • 6. 85. Monk S, Sakuntabhai A, Carter SA, Bryce SD, Cox R, Harrington L, et al. Refined genetic mapping of the darier locus to a <1-cM region of chromosome 12q24.1, and construction of a complete, high-resolution P1 artificial chromosome/bacterial artificial chromosome contig of the critical region. American Journal of Human Genetics 1998;62(4):890. 86. Rees JL. Tazarotene--New drug profile [commentary]. Drugs 1998;55(5):712. 87. Rees JL, Williams G. Sun, skin and cancer: from oncogenes to red hair genes. Horizons in Medicine, 1998:141. 88. Rees JL. Skin cancer. Journal of the Royal College of Physicians of London 1998;31(3):246. 89. Rees JL. FGFR2 mutations and acne. Lancet 1998;352:668. 90. Rees JL, Vogelstein B, Kinzler K. Skin cancer (Gorlin's syndrome). The genetic basis of human cancer. New York: McGraw-Hill, 1998:527. 91. Rees JL. The end of an age of metaphor. Review of Health care needs assessment: the epidemiology based needs assessment review of dermatology by H Williams, Radcliffe Press, 1997. Journal of Evaluation in Clinical Practice 1998;4(2):255. 92. Rees JL, Stanley JM, Mary EM. Molecular Biology of Squamous Carcinoma. Cutaneous Oncology: Pathophysiology, Diagnosis and Mangement: Blackwell Science, 1998:353. 93. Rees JL, Champion RH, Burton JL, Burns DA, Breathnach SM. Molecular Biology. Textbook of Dermatology: Blackwell Science, 1998:205. 94. Rees JL, Reynolds NJ. In This Issue. Journal of Investigative Dermatology 1998;111:917. 95. Smith R, Healy E, Siddiqui S, Flanagan N, Steijlen PM, Rosdahl I, et al. Melanocortin 1 receptor variants in an Irish population. Journal of Investigative Dermatology 1998;111(1):119. 96. Takata M, Rehman I, Rees JL. A trichilemmal carcinoma arising from a proliferating trichilemmal cyst: the loss of the wild-type p53 is a critical event in malignant transformation. Human Pathology 1998;29(2):193. 97. Turner RT, Dahl MGC, Shuster S, Rees JL. Mosaic atopic eczema cured by autotransplantation. Lancet 1998;352:961. 98. Birch-Machin MA, Healy E, Turner R, Haldane F, Belgaid CE, Darlington, et al. Mapping of monilethrix to the type II keratin gene cluster at chromosome 12q13 in three new families, including one with variable expressivity. British Journal of Dermatology 1997;137(3):339. 99. Rees JL, Healy E. Melanocortin receptors, red hair, and skin cancer. Journal of Investigative Dermatology Symposium Proceedings 1997;2(1):94. 100. Rees JL, Scriver CR, Beaudet AL, Sly WS, Valle D. Skin cancer. Metabolic and molecular basis of inherited diseases. New York: McGraw-Hill, 1997:CD -ROM version. 101. Rees JL, Altmeyer P, Hoffman K, StÅcker M. The genetics of actinic keratoses. Skin cancer and UV radiation. Berlin: Spriner-Verlag, 1997:700.
  • 7. 102. Rees JL. Review of 'Skin cancer', Leigh,I.M.; Newton-Bishop,J.A.; Kripke,M.L., published by Cold Spring Harbour Press, 1996. Journal of Investigative Dermatology 1997;108(6):Book Review. 103. Rehman I, Quinn AG, Takata M, Taylor AE, Rees JL. Low frequency of allelic loss in skin tumours from immunosuppressed individuals. British Journal of Cancer 1997;76(6):757. 104. Sikkink SK, Rehman I, Rees JL. Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer. Journal of Investigative Dermatology 1997;109(6):801. 105. Takata M, Rehman I, Rees JL. p53 mutation spectrum in Japanese Bowen's disease suggests a role for mutagens other than ultraviolet light. International Journal of Cancer 1997;71(3):370. 106. van Steensel MA, Steijlen PM, Rees JL. Molecular genetic approaches to skin disease: keratins and keratinisation. Journal of the Royal College of Physicians of London 1997;31(4):379. 107. de Berker D, Windebank K, Sviland L, Kingma DW, Carter R, Rees JL. Spontaneous regression in angiocentric T-cell lymphoma. British Journal of Dermatology 1996;134(3):554. 108. Healy E, Sikkink S, Rees JL. Infrequent mutation of p16INK4 in sporadic melanoma. Journal of Investigative Dermatology 1996;107(3):318. 109. Healy E, Belgaid CE, Takata M, Vahlquist A, Rehman I, Rigby H, et al. Allelotypes of primary cutaneous melanoma and benign melanocytic nevi. Cancer Research 1996;56(3):589. 110. Hinchliffe SA, Smith MD, Boon ME, Howard CV, Van Velzen D, Rees JL. Evidence for dissociation of histone mRNA expression from cellular proliferation in cutaneous human papillomavirus infection. Journal of Pathology 1996;178(3):249. 111. Rees JL, Healy E. Molecular genetic approaches to non-melanoma and melanoma skin cancer. Clinical & Experimental Dermatology 1996;21(4):253. 112. Rees JL. The melanoma epidemic: reality and artefact [editorial]. BMJ 1996;312(7024):137. 113. Rehman I, Takata M, Wu YY, Rees JL. Genetic change in actinic keratoses. Oncogene 1996;12(12):2483. 114. Takata M, Quinn AG, Hashimoto K, Rees JL. Low frequency of loss of heterozygosity at the nevoid basal cell carcinoma locus and other selected loci in appendageal tumors. Journal of Investigative Dermatology 1996;106(5):1141. 115. Valverde P, Healy E, Sikkink S, Haldane F, Thody AJ, Carothers A, et al. The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma. Human Molecular Genetics 1996;5(10):1663. 116. Waring AJ, Takata M, Rehman I, Rees JL. Loss of heterozygosity analysis of keratoacanthoma reveals multiple differences from cutaneous squamous cell carcinoma. British Journal of Cancer 1996;73(5):649. 117. de Berker D, Ibbotson S, Simpson NB, Matthews JN, Idle JR, Rees JL. Reduced experimental contact sensitivity in squamous cell but not basal cell carcinomas of skin. Lancet
  • 8. 1995;345(8947):425. 118. de Berker D, Rees JL. Normal sweat secretion rate in patients with alopecia areata. British Journal of Dermatology 1995;132(3):402. 119. el-Deiry WS, Tokino T, Waldman T, Oliner JD, Velculescu VE, Burrell M, et al. Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Research 1995;55(13):2910. 120. Healy E, Rehman I, Angus B, Rees JL. Loss of heterozygosity in sporadic primary cutaneous melanoma. Genes Chromosomes & Cancer 1995;12(2):152. 121. Healy E, Angus B, Lawrence CM, Rees JL. Prognostic value of Ki67 antigen expression in basal cell carcinomas. British Journal of Dermatology 1995;133(5):737. 122. Healy E, Holmes SC, Belgaid CE, Stephenson AM, McLean WH, Rees JL, et al. A gene for monilethrix is closely linked to the type II keratin gene cluster at 12q13. Human Molecular Genetics 1995;4(12):2399. 123. Healy E, Reynolds NJ, Smith MD, Harrison D, Doherty E, Campbell C, et al. Up-regulation of p21WAF1/CIP1 in psoriasis and after the application of irritants and tape stripping. Journal of Investigative Dermatology 1995;105(2):274. 124. Quinn AG, Healy E, Rehman I, Sikkink S, Rees JL. Microsatellite instability in human non- melanoma and melanoma skin cancer. Journal of Investigative Dermatology 1995;104(3):309. 125. Rees J. Rethinking consultants: Where medical science and human behaviour meet. BMJ 1995;310(6983):850. 126. Rees JL. p53 and the origins of skin cancer. Journal of Investigative Dermatology 1995;104(6):883. 127. Reese V. Dermatology in the cinema. Journal of the American Academy of Dermatology 1995;33(6):1030. 128. Smith MD, Healy E, Thompson V, Morley A, Rees JL. Use of in situ detection of histone mRNA in the assessment of epidermal proliferation: comparison with the Ki67 antigen and BrdU incorporation. British Journal of Dermatology 1995;132(3):359. 129. Valverde P, Healy E, Jackson I, Rees JL, Thody AJ. Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nature Genetics 1995;11(3):328. 130. Wainwright LJ, Middleton PG, Rees JL. Changes in mean telomere length in basal cell carcinomas of the skin. Genes Chromosomes & Cancer 1995;12(1):45. 131. Carter SA, Bryce SD, Munro CS, Healy E, Bashir R, Weissenbach J, et al. Linkage analyses in British pedigrees suggest a single locus for Darier disease and narrow the location to the interval between D12S105 and D12S129. Genomics 1994;24(2):378. 132. Coleman R, Malone M, Handfield-Jones S, Goodwin P, Rees J, Atherton, et al. Waxy keratoses of childhood. Clinical & Experimental Dermatology 1994;19(2):173.
  • 9. 133. Healy E, Reynolds NJ, Smith MD, Campbell C, Farr PM, Rees JL. Dissociation of erythema and p53 protein expression in human skin following UVB irradiation, and induction of p53 protein and mRNA following application of skin irritants. Journal of Investigative Dermatology 1994;103(4):493. 134. Munro CS, Carter S, Bryce S, Hall M, Rees JL, Kunkeler L, et al. A gene for pachyonychia congenita is closely linked to the keratin gene cluster on 17q12-q21. Journal of Medical Genetics 1994;31(9):675. 135. Quinn AG, Campbell C, Healy E, Rees JL. Chromosome 9 allele loss occurs in both basal and squamous cell carcinomas of the skin. Journal of Investigative Dermatology 1994;102(3):300. 136. Quinn AG, Sikkink S, Rees JL. Basal cell carcinomas and squamous cell carcinomas of human skin show distinct patterns of chromosome loss. Cancer Research 1994;54(17):4756. 137. Quinn AG, Sikkink S, Rees JL. Delineation of two distinct deleted regions on chromosome 9 in human non-melanoma skin cancers. Genes Chromosomes & Cancer 1994;11(4):222. 138. Rees J. Genetic alterations in non-melanoma skin cancer. Journal of Investigative Dermatology 1994;103(6):747. 139. Rehman I, Quinn AG, Healy E, Rees JL. High frequency of loss of heterozygosity in actinic keratoses, a usually benign disease. Lancet 1994;344(8925):788. 140. Smith MD, Rees JL. Wavelength-specific upregulation of keratin mRNA expression in response to ultraviolet radiation. Journal of Investigative Dermatology 1994;102(4):433. 141. Bashir R, Munro CS, Mason S, Stephenson A, Rees JL, Strachan T. Localisation of a gene for Darier's disease. Human Molecular Genetics 1993;2(11):1937. 142. Campbell C, Quinn AG, Ro YS, Angus B, Rees JL. p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin. Journal of Investigative Dermatology 1993;100(6):746. 143. Campbell C, Rees JL. The role of ras gene mutations in murine and human skin carcinogenesis. Skin Cancer 1993;8:245. 144. Campbell C, Quinn AG, Rees JL. Codon 12 Harvey-ras mutations are rare events in non-melanoma human skin cancer. British Journal of Dermatology 1993;128(2):111. 145. Campbell C, Quinn AG, Angus B, Rees JL. The relation between p53 mutation and p53 immunostaining in non-melanoma skin cancer. British Journal of Dermatology 1993;129(3):235. 146. Campbell C, Quinn AG, Angus B, Farr PM, Rees JL. Wavelength specific patterns of p53 induction in human skin following exposure to UV radiation. Cancer Research 1993;53(12):2697. 147. Rees JL, Priestly GC. Molecular genetics of skin disease. Molecular Aspects of Dermatology. Chichester: John Wiley and Sons, 1993:171. 148. Rees JL. Review of 'The skin microflora and microbial disease', Ed. WC Noble Cambridge University Press, 1993. BMJ 1993;307:272.
  • 10. 149. Ro YS, Cooper PN, Lee JA, Quinn AG, Harrison D, Lane D, et al. p53 protein expression in benign and malignant skin tumours. British Journal of Dermatology 1993;128(3):237. 150. Tiling-Grosse S, Rees J. Assessment of area of involvement in skin disease: a study using schematic figure outlines. British Journal of Dermatology 1993;128(1):69. 151. Munro CS, Rees JL, Shuster S. The unexpectedly rapid response of fungal nail infection to short duration therapy. Acta Dermato-Venereologica 1992;72(2):131. 152. Rees J. The molecular biology of retinoic acid receptors: orphan from good family seeks home. British Journal of Dermatology 1992;126(2):97. 153. Rees J. Forward dermatology [editorial]. BMJ 1992;304(6827):590. 154. Rees JL, Matthews JN, Friedmann PS. Delayed type hypersensitivity is abnormal in patients with lichen planus. Archives of Dermatological Research 1992;284(3):132. 155. Rees JL, Matthews JN, Friedmann PS. Quantifying anti-inflammatory agents' potency by measurement of response to dinitrochlorobenzene challenge. Journal of Dermatological Science 1992;4(1):1. 156. Fisher C, Angus B, Rees J. In-situ hybridization using digoxigenin-labelled probes in human skin. British Journal of Dermatology 1991;125(6):516. 157. Munro CS, Higgins EM, Ramsay B, McLelland J, Marks JM, Friedmann PS, et al. The mode of action of cyclosporing. Drug Investigation 1991;2(1):1. 158. Smith WC, Nakshatri H, Leroy P, Rees J, Chambon P. A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter. EMBO Journal 1991;10(8):2223. 159. Friedmann PS, Rees J, White SI, Matthews JN. Low-dose exposure to antigen induces sub-clinical sensitization. Clinical & Experimental Immunology 1990;81(3):507. 160. Rees JL, Friedmann PS, Matthews JN. Contact sensitivity to dinitrochlorobenzene is impaired in atopic subjects. Controversy revisited. Archives of Dermatology 1990;126(9):1173. 161. Rees JL, Friedmann PS, Matthews JN. The influence of area of application on sensitization by dinitrochlorobenzene. British Journal of Dermatology 1990;122(1):29. 162. Daly AK, Rees JL, Redfern CP. Nuclear retinoic-acid-binding proteins and receptors in retinoic- acid-responsive cell lines. Experimental Cell Biology 1989;57(6):339. 163. Rees JL, Pal B. Stimulated eccrine gland function in primary Sjogren's syndrome. Clinical & Experimental Dermatology 1989;14(3):191. 164. Rees JL, Friedmann PS, Matthews JN. Sex differences in susceptibility to development of contact hypersensitivity to dinitrochlorobenzene (DNCB). British Journal of Dermatology 1989;120(3):371. 165. Rees JL, Redfern CP. Expression of the alpha and beta retinoic acid receptors in skin. Journal of
  • 11. Investigative Dermatology 1989;93(6):818. 166. Rees JL, Daly AK, Redfern CP. Differential expression of the alpha and beta retinoic acid receptors in tissues of the rat. Biochemical Journal 1989;259:917. 167. Rees J, Marks JM. Two unusual cases of orf following trauma to the scalp. British Journal of Dermatology 1988;118(3):445. 168. Rees JL, Cox NH. Effect of isotretinoin on eccrine gland function. British Journal of Dermatology 1988;119(1):79. 169. Rees J. Aging and measures of bone mass. J.Clin.Expt.Gerontology 1982;4(2):115. 170. Rees JL. Secular changes in the incidence of proximal femoral fracture in Oxfordshire: a preliminary report. Community Medicine 1982;4(2):100. 171. Rees JL. Accuracy of hospital activity analysis data. BMJ 1982;284:1856. 172. Rees J, Shuster S. Pubertal induction of sweat gland activity. Clinical Science 1981;60(6):689.