Newsletter - November 3, 2011


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Latest Advances in Clinical Senology and Oncology

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  1. 1. Senology Newsletter Page 1 of 4 - Newsletter International Senologic and Oncologic  Scientific Community  "Connecting specialists worldwide" Editor-in-Chief: Gian Paolo Andreoletti, MD Subscribe Unsubscribe Contact Back Issues Connecting Specialists Worldwide Join us on Facebook®, Twitter®, YouTube®, LinkedIn®, SlideShare®, Flickr® and Doctorsbook® and share informations, opinions and suggestions. Check out Newspaperand follow our RSS feeds for real-time updates Literature Selection Hubbard RA et al.: "Cumulative probability of false-positive recall or biopsy recommendation after 10 years of screening mammography: a cohort study", Ann Intern Med. 2011 Oct 18;155(8):481-92 Takeshita T et al.: "Clinical Implications of Occult Metastases and Isolated Tumor Cells in Sentinel and Non-Sentinel Lymph Nodes in Early Breast Cancer Patients: Serial Step Section Analysis with Long- Term Follow-Up", Ann Surg Oncol. 2011 Oct 12. [Epub ahead of print] Han Y et al.: "Prognostic value of chemotherapy-induced neutropenia in early-stage breast cancer", Breast Cancer Res Treat. 2011 Oct 5. [Epub ahead of print] Arun B et al.: "Response to Neoadjuvant Systemic Therapy for Breast Cancer in BRCA Mutation Carriers and Noncarriers: A Single-Institution Experience", J Clin Oncol. 2011 Oct 1;29(28):3739-46 Mohammadianpanah M et al.: "The efficacy and safety of neoadjuvant chemotherapy +/- letrozole in postmenopausal women with locally advanced breast cancer: a randomized phase III clinical trial", Breast Cancer Res Treat. 2011 Oct 16. [Epub ahead of print] Stearns V et al.: "Preclinical and clinical evaluation of intraductally administered agents in early breast cancer", Sci Transl Med. 2011 Oct 26;3(106):106ra108 Regan MM et al.: "Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8·1 years median follow-up", Lancet Oncol. 2011 Oct 20. [Epub ahead of print] Slamon D et al.: "Adjuvant trastuzumab in HER2-positive breast cancer", N Engl J Med. 2011 Oct 6;365 (14):1273-83 Brufsky AM et al.: "Final 5-year results of Z-FAST trial: Adjuvant Zoledronic Acid Maintains Bone Mass in Postmenopausal Breast Cancer Patients Receiving Letrozole", Cancer. 2011 Oct 10 [Epub ahead of print] 03/11/2011
  2. 2. Senology Newsletter Page 2 of 4 Adkins FC et al.: "Triple-negative breast cancer is not a contraindication for breast conservation", Ann Surg Oncol. 2011 Oct;18(11):3164-73 Early Breast Cancer Trialists Collaborative Group (EBCTCG): "Effect of radiotherapy after breast- conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials", Lancet. 2011 Oct 19. [Epub ahead of print] Miao H et al.: "Incidence and Outcome of Male Breast Cancer: An International Population-Based Study", J Clin Oncol. 2011 Oct 3. [Epub ahead of print] Comment "Patients with small, node-negative HER2-positive breast carcinoma may benefit from trastuzumab therapy" - Ana Kiess, Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA ""Our study shows that women with small, node-negative HER2-positive breast cancer may benefit from trastuzumab therapy. These women actually have a significant risk of local recurrence in the breast after breast conservation therapy (~10%), but trastuzumab may reduce their risk to about 1%" (Comment on: Kiess AP et al.: "Adjuvant trastuzumab reduces locoregional recurrence in women who receive breast-conservation therapy for lymph node-negative, human epidermal growth factor receptor 2-positive breast cancer", Cancer. 2011 Sep 1. doi: 10.1002/cncr.26484. [Epub ahead of print]) Discussion Welch HG et al.: "Likelihood That a Woman With Screen-Detected Breast Cancer Has Had Her "Life Saved" by That Screening", Arch Intern Med. Published online October 24, 2011, doi:10.1001/archinternmed.2011.476 - What do you think about the conclusions of this study? Share your opinion on LinkedIn® Healthcare Companies News Oncotype DX Newsletter - Genomic Health Calendar of Events 1st Advanced Breast Cancer International Consensus Conference, November 3-5, 2011, Lisbon, Portugal IX Madrid Breast Cancer Conference, November 16 - 17, 2011, Madrid, Spain AORTIC (African Organisation for Research and Training in Cancer) - 8th International Conference, November 28 - December 2, 2011, Cairo, Egypt The 2011 CTRC-AACR San Antonio Breast Cancer Symposium, December 6-10, 2011, San Antonio, TX The World Cancer Immunotherapy Conference, January 25-26, 2012, San Diego, CA Fragments of History William S Halsted (New York, 1852-1922), "The Results of Operations for the Cure of Cancer of the Breast Performed at the Johns Hopkins Hospital from June, 1889, to January, 1894, Ann Surg. 1894 November; 20(5): 497–555: “Now we can state positively that cancer of the breast is a curable disease if operated upon properly and in time. I cannot emphasize too strongly the fact that internal metastases occur very early in cancer of the breast, and this is an additional reason for not losing a day in discussing the propriety of an operation" Literature Selection Gillgren P et al.: "2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial", Lancet. 2011 Oct 21. [Epub ahead of print] Chaturvedi AK et al.: "Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States", J Clin Oncol. 2011 Oct 3. [Epub ahead of print] 03/11/2011
  3. 3. Senology Newsletter Page 3 of 4 Palefsky JM et al.: "HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia", N Engl J Med. 2011 Oct 27;365(17):1576-1585 Hvid-Jensen F et al.: "Incidence of Adenocarcinoma among Patients with Barretts Esophagus", N Engl J Med. 2011 Oct 13;365(15):1375-83 Herbrik M et al.: "Diagnostic Accuracy of Virtual 18F-FDG PET/CT Bronchoscopy for the Detection of Lymph Node Metastases in Non-Small Cell Lung Cancer Patients", J Nucl Med. 2011 Oct;52(10):1520-5 Oken MM et al.: "Screening by Chest Radiograph and Lung Cancer Mortality: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Trial", JAMA. 2011 Oct 26. [Epub ahead of print] Quoix E et al.: "Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non- small-cell lung cancer: a controlled phase 2B trial", Lancet Oncol. 2011 Oct 21. [Epub ahead of print] Ruge M et al.: "Stereotactic Brachytherapy With Iodine-125 Seeds for the Treatment of Inoperable Low-Grade Gliomas in Children: Long-Term Outcome", J Clin Oncol. 2011 Oct 3. [Epub ahead of print] Yang D et al.: "Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer", JAMA. 2011 Oct 12;306(14):1557-65 Klein EA et al.: "Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)", JAMA. 2011 Oct 12;306(14):1549-56 Miyatake H et al.: "Effect of Previous Interferon Treatment on Outcome After Curative Treatment for Hepatitis C Virus-Related Hepatocellular Carcinoma", Dig Dis Sci. 2011 Oct 12. [Epub ahead of print] Garcia-Donas J et al.: "Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study", Lancet Oncol. 2011 Oct 17. [Epub ahead of print] Discussion "Screening for Prostate Cancer - A Review of the Evidence for the U.S. Preventive Services Task Force" - "Prostate cancer screening guidelines called into question", Dana-Farber Cancer Institute - Share your opinion on LinkedIn® Literature Selection Vesco KK et al.: "Risk Factors and Other Epidemiologic Considerations for Cervical Cancer Screening: A Narrative Review for the U.S. Preventive Services Task Force", Ann Intern Med. 2011 Oct 17. [Epub ahead of print] Whitlock EP et al.: "Liquid-Based Cytology and Human Papillomavirus Testing to Screen for Cervical Cancer: A Systematic Review for the U.S. Preventive Services Task Force", Ann Intern Med. 2011 Oct 17. [Epub ahead of print] collaborates with - "Breast cancer questions, answers, and support". Follow the Expert Q&A Workshops and join the conversation Stay informed.... Recent Advances in Clinical Medicine OConnor P et al.: "Randomized trial of oral teriflunomide for relapsing multiple sclerosis", N Engl J Med. 2011 Oct 6;365(14):1293-303 03/11/2011
  4. 4. Senology Newsletter Page 4 of 4 Unsubscribe       www.senology.org 03/11/2011