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What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
What Is Biotechnology?
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What Is Biotechnology?

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  • 1. What is Biotechnology?
  • 2. Biotechnology A wide ranging scientific field which includes the manipulation of living organisms that results in new products or processes by that cell.
  • 3. How Old Is Biotechnology ? 10,000 BC Domesticating Crops Domesticating Animals 8,000-9,000 BC 6,000 BC Brewing Beer 4,000 BC Leavening Bread 1880’s Production of Vaccines 1940’s Production of Antibiotics 1980’s Use of genetically modified organisms
  • 4. Discovered the Laws Governing the Genetic Inheritance of Traits by Scientific Experimentation Founded Modern Genetics
  • 5. How Old is Modern Biotechnology?
  • 6.  
  • 7. Genetically Modified Animals 1983 Transgenic Mice 1997 Cloned sheep
  • 8.  
  • 9. Modern Biotechnology
    • Molecular Biology
    • - microbiology
    • - biochemistry
    • - cell biology
    • Molecular Genetics
    • Genetic Engineering: Moving a gene from one organism to another
    • - chemical engineering
    • - biomanufacturing
  • 10.  
  • 11. Genetically Modifying DNA Integration of Foreign DNA into Existing DNA
  • 12. Gene Manipulation and Introduction in Plant Biotechnology
  • 13. Restriction Enzyme and Ligase
  • 14. Examples of Plant Transformations
  • 15. Biotechnology Industry
    • As of December 2003:
    • There are 1,473 companies & 198,300 employees
    • 300 Biotechnology drug products and vaccines are in clinical trials
    • Biotechnology foods include papaya, corn and soybeans
    • Environmental biotechnology used to clean up hazardous spills
    • Forensic medicine is used for identification by DNA Fingerprinting
    • Regulated by the FDA
    • More than 323 million people worldwide have been helped by Biotech
  • 16. Fermentation Vessels in Biomanufacturing Plant
  • 17. Biopharmaceuticals Defined
    • Any biology-based therapeutic that structurally mimics components found in the body
    • Includes: recombinant proteins, antibodies, peptides, antisense nucleotides, therapeutic genes, therapeutic vaccines
  • 18. Biotechnology Applications in Health and Medicine
    • Protein Pharmaceuticals
    • Vaccines & Therapeutic Agents
    • Diagnostics: Protein or DNA Based
    • Gene Therapy
    • Stem Cell Research
    • Cancer Treatment
  • 19. Biotech Products in Use
    • Epogen,neupogen (Amgen)
    • TPA, Insulin
    • (Genentech)
    • Interferon Beta
    • (Biogenidec)
    • Algucerase
    • (Genzyme)
    • Anemia, chemotherapy effects
    • Blood clot remover,
    • diabetic treatment
    • Treatment of Multiple
    • Sclerosis
    • Gaucher’s Disease
    • lysosomal storage
    • genetic defect
  • 20. Gene Therapy
    • Insertion of a new “healthy” gene into the organism to provide needed (usually) proteins, hormones etc.
    • Gene is carried into the host by a viral
    • vector that has been disabled
    • Can provide relief for many genetic diseases
    • Problems: Jessie Gelsinger, xscid babies
    • immune responses, and cancer
  • 21. Cancer Therapy
    • Factors that inhibit blood vessel growth
    • Toxic chemicals delivered by antibodies to
    • specific cancer cells
    • Killer gene is delivered to tumor cells by
    • specific binding to the cancer cell
  • 22. Stem Cells
    • Can be used to replace damaged tissue
    • Examples: Heart cells, Parkinson’s disease and Pancreatic cells in Diabetes
    • Ethical issues and lack of cells to work with have slowed this research

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