Kimberly A. Greer
                                 4302 Bentwood Drive
                               College Station, TX ...
Greer- 2
Genetic Savings and Clone, College Station, Texas
Consultant, April 2002- May 2002
    instructed graduate and u...
Greer- 3
      Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas
      Student Research A...
Greer- 4
Canterberry, S.C.*, K.A. Greer*, C. Hitte, C. Andre, K. Murphy. 2005. Aging-associated
loci in Canis familiaris. ...
Greer- 5
Bennett, G.D., K.A. Greer, R.H. Levy, J. Slattery. 1993. Stiripentol protection from the
teratogenic effects of p...
single stand conformational polymorphism (SSCP). American Journal of Human Genetics
    59(4): A212.

                    ...
Genetics Laboratory, College Station, Texas; April 1996
      Methodologies for Producing Transgenic Animals.



Greer- 7
...
Meeting, San Antonio, Texas; March 1996
      Folate Receptor Gene Variants: Implication for Susceptibility to Neural Tube...
Texas A&M University, Vice President for Research Travel Award (PI)
Preliminary examination of oxidative stress methanimsm...
Community Involvement:
     Leaps N Bounds Agility Center; 1999- present
     Pug Dog Club of Greater San Antonio; 2001- p...
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  1. 1. Kimberly A. Greer 4302 Bentwood Drive College Station, TX 77845 Office: (979) 458-0128 Laboratory: (979) 862-2014 Home: (979) 690-9023 Electronic mail: kgreer@cvm.tamu.edu Citizenship: United States of America Education: Texas A&M University, College Station, Texas Doctor of Philosophy, Genetics, May 2002 Texas A&M University, College Station, Texas Master of Science, Genetics, December 1996 Texas A&M University, College Station, Texas Bachelor of Science, Genetics, December 1992 Research Experience: Texas A&M University, Department of Veterinary Pathobiology; College Station, Texas Research Assistant Professor, January 2005-present  laboratory focus is on canine hereditary disease and aging/ longevity  techniques include a wide variety of molecular biology and molecular genetic techniques  teach undergraduates laboratory methods, techniques, and theory  serve on graduate committees  guest lecture in public venues, veterinary courses, and undergraduate courses Texas A&M University, Department of Veterinary Pathobiology; College Station, Texas Assistant Research Scientist, May 2002- January 2005 Postdoctoral appointment; funded by NIH F32 fellowship (KA Greer, PI)  directed day to day activities of 13 member laboratory  provided undergraduate and graduate student project guidance and instruction  designed and carried out aging and longevity studies  designed and carried out necrotizing encephalitis studies  established largest database and biological specimen set for Pug Dog Encephalitis  established canine DNA bank of 170+ independent breeds  obtained grant funding for projects (as PI)  wrote, edited, and published manuscripts Eli Lilly and Company, Investigative Toxicology; Greenfield, Indiana Visiting Scientist, June 2003- July 2003  completed microarray project utilizing a proprietary Affymetrix canine oligo array  isolated canine RNA from various tissues, synthesized cRNA, performed chip hybridization, evaluated resulting data  wrote manuscript of results and published in Mammalian Genome
  2. 2. Greer- 2 Genetic Savings and Clone, College Station, Texas Consultant, April 2002- May 2002  instructed graduate and undergraduate students in laboratory theory and techniques  designed and guided student research projects  evaluated standard operating procedures, proposed new methodology to operate the laboratory more efficiently; significantly reduced laboratory operating cost Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas Graduate Research Assistant, January 1997- August 1999  conducted independent research  evaluated various populations of people for susceptibility to neural tube defect transmission  evaluated the effects of folate supplementation on decreased risk of neural tube defects in susceptible murine models  evaluated murine tissue expression of folate binding proteins and the reduced folate carrier  established an in vitro model for evaluating intracellular effects of oxidative stress  trained graduate students and professional students  trained and supervised technicians and undergraduates National Institutes of Health, National Human Genome Research Institute; Bethesda, Maryland Visiting Scientist, March 1998-July 1998  conducted linkage analysis on F1 hybrid mice to correlate genes with developmental toxicology of Phenobarbital  presented research findings  transferred technology to laboratory in Texas Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas Research Assistant II and Lab Manager, January 1995- December 1996  isolated, sequenced, and characterized the Reduced Folate Carrier 1 gene in the murine  set up laboratory RNA isolation lab, experimental techniques, and standardized methodology Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas Research Assistant I and Lab Manager, December 1992- December 1994  responsible for maintenance and propagation of laboratory plasmid stocks  maintained murine breeding colony  treated murine colony with targeted anticonvulsant drugs  evaluated the efficacy of steripentol (STP) for FDA consideration  trained graduate, professional, and undergraduate students in laboratory techniques and murine colony maintenance
  3. 3. Greer- 3 Texas A&M University, Veterinary Anatomy and Public Health; College Station, Texas Student Research Assistant, August 1992- December 1992  responsible for maintenance and propagation of laboratory plasmid stocks  maintained murine breeding colony  treated murine colony with targeted anticonvulsant drugs Texas A&M University, Entomology, College Station, Texas Student Research Assistant, December 1991- August 1992  responsible for maintenance and propagation of laboratory plasmid stocks  cloned and subcloned genes pertaining to Teaching Experience: Texas A&M University, College of Veterinary Medicine; College Station, Texas Teaching Assistant: Biochemical Genetics, September 1999- December 2001  lectured each semester  offered tutorial lectures twice per week  offered additional office hours for individual assistance  wrote exam questions  graded examinations and weekly quizzes Texas A&M University, Department of Biochemistry and Biophysics; College Station, Texas; Teaching Assistant: Genetics 301 Laboratory, January 1996-May 1996  lectured twice weekly  wrote weekly laboratory evaluations and quizzes  graded weekly laboratory performance and quizzes  offered office hours for individual assistance Publications: Greer, K.A., S. Canterberry, K. Murphy. 2007. Statistical analysis regarding the effects of height and weight on lifespan of the domestic dog. Research in Veterinary Science 82(2): 208-214. Pine M.D., K.A. Greer, D. Busbee. 2007. Comparison of Reactive Oxygen Scavenging Systems between a Cetacean (DKN1) and a Porcine Renal Epithelial Cell Line (LLC-PK1). Comparative Biochemistry and Physiology 147: 550–555 . Greer, K.A., M. Higgins, M. Cox, T.P. Ryan, B.R. Berridge, C.E. Kashtan, G.E. Lees, K.E. Murphy. 2006. Gene Expression Analysis in a Canine Model of X-linked Alport Syndrome. Mammalian Genome 17(9): 976-990. Greer, K.A., M. Pine, D. Busbee. 2005. An in vitro model of excess intracellular reactive oxygen species. AGE 27(2): 97-105.
  4. 4. Greer- 4 Canterberry, S.C.*, K.A. Greer*, C. Hitte, C. Andre, K. Murphy. 2005. Aging-associated loci in Canis familiaris. Growth, Development, and Aging 69 (2): 101-113; *indicates equal authorship. Lundberg, Y.W., Cabrera R.M.*, Greer K.A.*, Zhao J, Garg R, R.H. Finnell. 2004. Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mammalian Genome 15: 361-369; *indicates equal authorship. Greer, K.A., E.J. Cargill, M.L. Cox, L.A. Clark, K.L. Tsai, K.M. Credille, R.W. Dunstan, P.J. Venta and K.E. Murphy. 2003. Digging up the canine genome – a tale to wag about. Cytogenetic and Genome Research 102(1-4): 249-253. Pine, M., M. Schroeder, K. Greer, R. Hokanson, and D. Busbee. 2003. Generation and Partial Characterization of a Transformed Cetacean Cell Line. Aquatic Toxicology 67(4): 195-202. Barber, R.C., G.D. Bennett, K.A. Greer, R.H. Finnell. 1999. Expression patterns of folate binding proteins one and two in the developing mouse embryo. Molecular Genetics and Metabolism 66(1): 31-39. Barber, R.C., E.J. Lammer, G.M. Shaw, K.A. Greer, R.H. Finnell. 1999. The role of folate transport and metabolism in neural tube defect risk. Molecular Genetics and Metabolism 66(1): 1-9. Barber, R.C., G.M. Shaw, E.J. Lammer, K.A. Greer, T.A. Biela, S.W. Lacey, C.R. Wasserman, R.H. Finnell. 1998. Lack of Association between Mutations in the Folate Receptor-α Gene and Spina Bifida. American Journal of Medical Genetics 76(4): 310-317. Finnell, R.H., K.A. Greer, R.C. Barber, J.A. Piedrahita. 1998. Neural tube and craniofacial defects with special emphasis on folate pathway genes. Critical Reviews in Oral Biology Medicine 9(1): 38-53. Greer, K.A., P.E. Bonnen, N. Jimenez, E.J. Lammer, S.W. Lacey, G.M. Shaw, and R.H. Finnell. 1995. Folate receptor gene variants and neural tube defect occurrence. Teratology 51(3): 162. Finnell, R.H., K.A. Greer, E. Lammer, S. Lacey, G. Shaw. 1994. Folate receptor gene variants and neural tube defect occurrence. American Journal of Human Genetics 55(3): 870. Musselman, A.C., G.D. Bennett, K.A. Greer, J. Eberwine, R.H. Finnell. 1994. Preliminary evidence of phenytoin-induced alterations in early embryonic gene expression in a mouse model. Reproductive Toxicology 8(5): 383-395.
  5. 5. Greer- 5 Bennett, G.D., K.A. Greer, R.H. Levy, J. Slattery. 1993. Stiripentol protection from the teratogenic effects of phenytoin and carbamezapine. Teratology 47(5): 406. Submitted/In Preparation Manuscripts: Greer, K.A., S.J. Schatzberg, B.F. Porter, K.A. Jones, T.R. Famula, K.M. Murphy. Heritability and transmission analysis of Pug Dog Encephalitis. (in prep, Journal of Veterinary Medicine) Greer, K.A., P.W. Daly, W. Ji, K. E. Murphy, J. J. Callanan. Etiological determination of breed specific meningoencephalitis via gene expression analyses. (in prep, Journal of Neuroinflammation). White, J., J. Levine, B. Porter, S. Schatzberg, K.A. Greer. Magnetic resonance imaging characterization of confirmed Pug Dog Encephalitis. (in prep, Journal of Veterinary Medicine) Porter B., R. Storts, J. Levine, K.A. Greer. Distinguishing histopathology of Pug Dog Encephalitis compared to granulomatous meningoencephalitis. (in prep, Journal of Veterinary Medicine). Greer, K.A., S.C. Canterberry, K.E. Murphy. Longevity associated, breed specific single nucleotide polymorphisms in C. familiaris. (in prep, AGE). Abstracts: Greer, K.A., R.H. Finnell, W. Pavan, L.G. Biesecker. 1998. Linkage mapping of a major susceptibility locus for valproic acid induced neural tube defects in the mouse. American Journal of Human Genetics 63(4): A1684. Greer, K.A., J.A. Piedrahita, G.D. Bennett, B. Oetama, R.H. Finnell. 1997. Expression of the murine folate binding proteins 1 and 2 and the reduced folate carrier gene. American Journal of Human Genetics 61(4): A993 Barber, R.C., G.D. Bennett, K.A. Greer, R.H. Finnell. 1997. Expression of folate binding proteins one and two in the SWV/Fnn mouse. American Journal of Human Genetics 61(4): A166. Greer, K.A., J. Piedrahita, B. Oetama, B. Barber, R. H. Finnell. 1996. Isolation and characterization of the reduced folate carrier in the murine system. American Journal of Human Genetics 59(4): A2137. Barber, R.C., K. A. Greer, G.M. Shaw, C.R. Wasserman, E.J. Lammer, R.H. Finnell. 1996. Screening methods for unknown polymorphisms: dideoxy fingerprinting (ddF) vs.
  6. 6. single stand conformational polymorphism (SSCP). American Journal of Human Genetics 59(4): A212. Greer- 6 Mentorship: Graduate student committee Sarah Zienko, Genetics Undergraduate supervisor and research mentor Kimberly Jones, Biomedical Science, currently enrolled at TAMU School of Veterinary Medicine Mary Wallace, Animal Science, currently applying for graduate school Jennifer Wickline, Biomedical Science, currently applying for vet school Robert Shaw, Poultry Agriculture Sharon Ulah, Biomedical Science Invited Lectures: Pug Dog Club of America, National Specialty, San Antonio, TX; September 2005 Necrotizing Meningoencephalitis: Our Latest Accomplishments Towards Transmission Analysis Borzoi Club of the United States of America, National Specialty, Dallas, Texas; April 2005 Canine Genetic Developments and Borzoi Health Pug Dog Club of America, National Specialty, Olympia, Washington; September 2004 The Past, Present, and Future of Necrotizing Meningoencephalitis Research. Veterinary Histology, College Station, Texas; April 2004, April 2002 A Day in the Life of an Insulin Dependent Diabetic. Pug Dog Club of Greater San Antonio, Regional Specialty, San Antonio, Texas; March 2004 Recent Advances in Transmission Analysis of Necrotizing Meningoencephalitis in the Pug Dog (PDE). Pug Dog Club of America, National Specialty, Sturbridge, Massachusetts; October 2003 Transmission Analysis of Necrotizing Meningoencephalitis in the Pug Dog (PDE). Old English Sheepdog National Specialty, Waco, Texas; October 2002 Understanding Hereditary Diseases of the Domestic Dog: A Tale of Two Approaches. March of Dimes Lecture Series, Bryan High School Child Development, Bryan, Texas; April 1996 The various causes of birth defects and how we can prevent the preventable defects.
  7. 7. Genetics Laboratory, College Station, Texas; April 1996 Methodologies for Producing Transgenic Animals. Greer- 7 Texas Department of Health, Austin, Texas; July 1994 The Implications of Folate Supplementation. Human Genetics College Station, Texas; April 1994 The Incidence of Neural Tube Defects on the Texas-Mexico Border. Academic Conferences: Gordon Research Conference, Biology of Aging, Ventura, CA; February 2006 Deciphering Mechanisms of Aging in C. familiaris (Selected as one of ten from 75 posters) Marine Biological Laboratories, Molecular Biology of Aging series, Woods Hole, MA, August 2004; Optimization and utilization of the comet assay for evaluating DNA repair in mammalian aging. American Aging Association, Oakland, California; June 2005 Investigation of the Domestic Dog (Canis familiaris) for Determination of Genetic Factors in Longevity Nathan Shock Aging Center Conference on Aging: Oxidative Stress, Bandera, Texas; October 2004 Understanding the genetics of aging: a canine model. American Aging Association, St. Petersburg, Florida; June 2004 Understanding the genetics of aging: a canine model International Workshop on Dog Genetics, Uppsala, Sweden; May 2002 Genetic Analysis of Canine X-linked Alport Syndrome in a Family of Mixed Breed Dogs. National Institutes of Health, Bethesda, Maryland; July 1998 Linkage mapping of a major susceptibility locus for VPA-induced NTDs utilizing a whole genome scan of a backcross system. American Association of Human Genetics, Baltimore, Maryland; October 1997 Expression of the Murine Folate Binding Proteins 1 & 2 and the Reduced Folate Carrier Gene. March of Dimes and the American College of Medical Genetics, Joint Clinical
  8. 8. Meeting, San Antonio, Texas; March 1996 Folate Receptor Gene Variants: Implication for Susceptibility to Neural Tube Defects. March of Dimes Conference, San Antonio, Texas, March 1994 Neural Tube Defects and Folate Supplementation. Greer- 8 Awards: Gordon Research Conference, Biology of Aging, Ventura, California; February 2006 Poster Presenter: Oxidative stress mechanisms of aging in C. Familiaris Marine Biological Laboratories Course Fellowship; Molecular Biology of Aging, Special Topics Course, August 2004 Ellison Medical Foundation international competition for attending its fully sponsored lecture and laboratory course (three week course) Woods Hole, Massachusetts; Summer Institute on Aging Research Award, Queenstown, Maryland; July 2004 NIH/NIA national competition for attending its fully sponsored summer institute (one week course) NIH/NIA, National Research Service Award Postdoctoral Fellowship, 2003-2005 Understanding Genetics of Aging: Canis familiaris model Lexington Who’s Who, Association of Business Leaders and Professionals, 2000 Gamma Sigma Delta, The Honor Society of Agriculture 1998-2001 Center for Environmental and Rural Health, Graduate Research Assistantship 1997-1998 Professional Affiliations: American Aging Association; 2004-present American Association for the Advancement of Science; 1998-present American Association of University Women; 1996-present Texas A&M University, Graduate Faculty; 2003-present Texas Genetics Society; 2003-present Professional Services: Journal reviews: Cytogenetic and Genome Research, Genomics, Mammalian Genome Proposal reviews: Wellcome Trust, American Kennel Club-Canine Health Foundation Texas Veterinary Diagnostic Center, Emergency Response Laboratory Reserve Force Grant Awards: AKC-CHF, Grant No. 640 (PI) Linkage Disequilibrium Analysis of Markers Associated with Pug Dog Encephalitis; 2006-2008
  9. 9. Texas A&M University, Vice President for Research Travel Award (PI) Preliminary examination of oxidative stress methanimsms of aging in C. familiaris; 2005-2006 Greer- 9 NIH/NIA, F32 National Research Service Award (PI) Understanding Genetics of Aging: Canis familiaris model; 2003-2005 Greater St. Louis Pug Dog Club, Research Grant Award (PI) Club award towards Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog: Collection Phase; 2002-2003 AKC-CHF, Grant No. 2650 (Co-PI) Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog; 2003-2004 Pug Dog Club of Northern CA, Research Grant Award (PI) Club award towards Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog: Collection Phase; 2002-2003 AKC-CHF, Grant No. 2501 (PI) Transmission Analysis of Breed Specific Necrotizing Encephalitis in the Pug Dog: Collection Phase; 2002-2003 Awards Pending: (Proposals to be submitted 2006-2007 fiscal year) NIA R03: PA-03-067 (PI) Age-related changes in tissue function; 2007-2009 NINDS/ NIA R21: PAS-03-092 (PI) Gene discovery in a complex neurological disorder; 2008-2009 Waltham Foundation (PI) Dietary modification of oxidative stress to lend healthy extended longevity; 2007-2009 Center for Environmental and Rural Health, Pilot Projects (PI) Oxidative stress effects on healthy aging and longevity; 2007-2008 Whitehall Foundation Necrotizing encephalitis, cytokines, dementia, and disorientation; 2007-2009 Morris Animal Foundation Molecular genetic analyses of canine necrotizing encephalitis; 2007-2008 Graduate Women in Science Molecular mechanisms of aging influenced by oxidative stress exposures; 2007-2008 Texas Higher Education Coordinating Board (PI) Cellular senescence associations with environmental oxidative stressors; 2007-2008
  10. 10. Community Involvement: Leaps N Bounds Agility Center; 1999- present Pug Dog Club of Greater San Antonio; 2001- present Greer- 10 Forest Ridge Elementary PTO; 2005- 2006 Pug Dog Club of America, 2005 National Organization Committee; 2003-2005 Brazos Valley Montessori School Parent Council; 2003-2005 Pug Rescue of Southeast Texas, PRoSET Member 1997-2004 Executive Board Member 1997-2002 Adoption Committee Chair 2000-2002 Brazos Valley Montessori School 2004 Spring Discovery Fair Chairman; 2003- 2004 (community-wide school fundraiser) Puppy Love Dog Obedience and Behavior Center, Agility Trainer; 2002 College Station Middle School Science Fair Judge; 2001 Brazos Valley Kennel Club; 1998-1999

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