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  • 1. Angus W. MacDonald, III, Ph.D. University of Minnesota Department of Psychology N218 Elliot Hall, 75 E. River Rd Minneapolis, Minnesota, 55455 612-624-3813 email: angus@umn.edu ___________________________________________________________________________________ _ Assistant Professor, University of Minnesota 2003 - present Primary Appointment: Clinical Science and Psychopathology Research Program, Department of Psychology Secondary Appointments: Cognitive and Biological Sciences Program, Dept. Psychology Behavioral Genetics Program, Dept. Psychology Biological Psychopathology Program, Dept. Psychology Center for Cognitive Sciences Graduate Program in Neuroscience University of Minnesota School of Medicine, Department of Psychiatry Director: Translational Research in Cognitive and Affective Mechanisms laboratory My laboratory explores questions in basic cognitive and affective neuroscience, the biological bases of psychopathology, and the measurement of group differences. Methodologies include functional magnetic resonance imaging (fMRI), behavioral genetics (twin and family studies), clinical assessment and cognitive testing. Current research includes (1) understanding how executive control mechanisms, which are associated with prefrontal cortex functioning, modulate attention, affective processing, social interactions and decision-making; (2) evaluating how impairments in such mechanisms may be related to schizophrenia and the genes associated with schizophrenia; and (3) methods development for analyzing fMRI, and psychometric confounds in the measurement of group differences. URL: www.psych.umn.edu/research/tricam/ EDUCATION Post-Doctoral Fellowship 2001-2002 Clinical Cognitive Neuroscience Laboratory Western Psychiatric Institute & Clinic Mentor: Cameron Carter, M.D. Ph.D. University of Pittsburgh Graduation Date: August 2001 Clinical Psychology Program, Department of Psychology Interdisciplinary Training Program: Center for the Neural Basis of Cognition Clinical Internship: Western Psychiatric Institute & Clinic Co-advisors: Michael F. Pogue-Geile, Ph.D. & Cameron Carter, M.D. B.A. Amherst College, Amherst, MA Graduation Date: December 1990 Psychology & Philosophy Majors
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  • 3. 3 AWARDS & HONORS Young Investigator Award (2005, National Alliance for Research on Schizophrenia and Depression) Bassell Award for Excellence in Psychological Research (2000, University of Pittsburgh) Organization for Human Brain Mapping, Full Travel Fellowship (2000) Center for the Neural Basis of Cognition Training Fellowship (1998, National Science Foundation) MEMBERSHIPS IN PROFESSIONAL SOCIETIES American Association for the Advancement of Science American Psychological Association, Division 12 (Society for the Science of Clinical Psychology) Behavior Genetics Association Cognitive Neuroscience Society Society For Neuroscience Society for Research in Psychopathology GRANTS Grants Awarded Grant-in-Aid of Research, Artistry and Scholarship, University of Minnesota, “Advanced Methods for Dissociating Cognitive Control Mechanisms in fMRI.” $25,000 total direct expenses. A.W. MacDonald, III, Principle Investigator. July 2003 – December 2005. Clinical Research Feasibility Funding (CReFF). University of Minnesota General Clinical Research Center. “Changes in Cortical Activation with Cognitive Rehabilitation in Schizophrenia.” $40,000 total direct costs. A.W. MacDonald, III, Principle Investigator. December 2003 – November 2005. National Alliance for Research in Schizophrenia and Depression, Young Investigator Award. “The Genetic and Neural Basis of Paranoia: A Functional MRI Study in Twins.” $60,000 total direct costs. A.W. MacDonald, III, Principle Investigator. July 2005 – June 2007. R01 National Institute of Mental Health, “Cognitive Neurogenetics of Schizophrenia.” $1,000,000 direct expenses, approx. $140,000 total site specific direct costs. C.S. Carter, Principal Investigator, A.W. MacDonald, III, Co-Investigator and Site Project Director. December 2003 – November 2008. R24 National Institute of Mental Health, “Aberrant Cortical Dynamics in Schizophrenia.” $725,000 total direct expenses, approx. $142,000 total site specific direct costs. S.R. Sponheim, Principal Investigator, A.W. MacDonald, III, Co-Principle Investigator and Site Project Director. July 2004 – June 2007. Merit Review, Veteran’s Administration. “Neural Phenotype-Genotype Associations in Schizophrenia.” $799,400 total direct expenses, approx $240,000 total site specific direct costs. S.R. Sponheim, Principal Investigator, A.W. MacDonald, III, Co-Investigator. April 2005 – March 2010. National Institutes of Health/NCRR, Biomedical Informatics Research Network (BIRN).
  • 4. 4 “Functional Imaging Research in Schizophrenia Testbed – FIRST BIRN.” $1,000,000 total site specific direct costs. S.G. Potkin, Principal Investigator, K. O. Lim, Project Director, A.W. MacDonald, III, Co-Investigator. October 2002 – November 2005. P01 National Institute of Mental Health. “Trait fear and fearlessness in humans.” $978,848 total site specific direct costs. P. Lang, Principle Investigator, C. J. Patrick, Program Director, A.W. MacDonald, III, Co-Investigator. Funding pending. Magnetic Resonance Imaging Piloting Grants (Center for Magnetic Resonance Research) “Comparison of Event-Related fMRI Designs for Compound Trial-Types.” 30 pilot hours. A.W. MacDonald, III, Principle Investigator. June 2003 – May 2004. “Genetic and Environmental Effects on Brain Structure and Function.” 10 paid+ 30 pilot hours. W.G. Iacono, Principle Investigator, A.W. MacDonald, III, Co-Investigator. February 2003 – November 2004. “Equilibrium of Sequential Games: an event-related fMRI Study.” 10 paid + 20 pilot hours. A. Rusticini. A.W. MacDonald, III, Co-Investigator. September 2004 – February 2005. “Neural Mediators of Attraction, Acceptance, and Rejection.” 20 pilot hours. C. Marsolek, Principle Investigator, A.W. MacDonald, III, Co-Investigator. September 2004 – February 2005. “Neural Substrates of Impaired Vigilance in Siblings of Schizophrenia Patients.” 20 pilot hours. S.R. Sponheim, Principle Investigator, Angus W. MacDonald, III, Co-Investigator. October 2004 – March 2005. Grants Pending R03 National Institutes of Mental Health, “fMRI of Control Over Habitual and Emotional Responses.” $100,000 direct expenses. A.W. MacDonald, III, Principle Investigator. (1st priority score 212, to be resubmitted July 2005) R24 National Institute of Drug Abuse, “Impulsivity in Addiction.” $1,500,000 direct costs. K.O. Lim, Principle Investigator. Neurocognitive and Behavioral Core. $210,000 direct core costs. A.W. MacDonald, III, Core Director. (Submitted 16 November 2004) R24 National Institute of Child Health and Human Development, “Functional Imaging of Brain Recovery.” $3,500,000 direct costs. K.O. Lim, Principle Investigator. A.W. MacDonald, III, Co-Investigator. (Submitted 17 November 2004) R01 National Institute of Mental Health, “White Matter Abnormalities in Schizophrenia“ $2,434,162 total direct costs. K.O. Lim, Principle Investigator, A.W. MacDonald, III, Co- Investigator. (1st priority score 169, 17.8%ile, resubmitted 1 March 2005) PUBLICATIONS
  • 5. 5 Peer-reviewed Journal Articles Snitz, B.E., MacDonald, A.W., III, Cohen, J.D., Becker, T., Carter, C.S. (in press). Lateral and Medial Hypofrontality in First-Episode Schizophrenia: Functional Activity in a Medication-Naïve State and Effects of Short-Term Atypical Antipsychotic Treatment. American Journal of Psychiatry. Holmes, A.J., MacDonald, A.W., III, Cameron S. Carter, C.S., Barch, D.M., Stenger, V.A., Cohen, J.D. (in press). Prefrontal Functioning During Context Processing in Schizophrenia and Major Depression: An Event-Related fMRI study. Schizophrenia Research. Kerns, J.G., Cohen, J.D., MacDonald, A.W, III, Johnson, M.K., Stenger, V.A., Aizenstein, H., Carter, C.S. (in press). Decreased Conflict and Error-Related Activity in the Anterior Cingulate Cortex in Schizophrenia. American Journal of Psychiatry. MacDonald, A.W., III, Carter, C.S., Kerns, J.G., Ursu, S., Barch, D., Holmes, A.J., Stenger, V.A, & Cohen, J.D. (2005). Specificity of Prefrontal Dysfunction and Context Processing Deficits to Schizophrenia in an Unmedicated First-Episode Psychotic Sample. American Journal of Psychiatry, 162, 475-484. Kerns, J.G., Cohen, J.D., MacDonald, A.W., III, Cho, R.Y., Stenger, V.A., & Carter, C.S. (2004). Anterior cingulate conflict monitoring and adjustments in control. Science, 303, 1023-1026. MacDonald, A.W., III, & Carter, C.S. (2003). Event-related fMRI study of context processing in the dorsolateral prefrontal cortex of patients with schizophrenia. Journal of Abnormal Psychology, 112, 689-697. MacDonald, A.W., III. (2003). Reconciling Schizophrenic Deficits in Top-down and Bottom-up Processes -- Not Yet: Commentary on Phillips and Silverstein. Brain and Behavior Sciences, 26, 96. MacDonald, A.W., III, Pogue-Geile, M.F, Johnson, M.K. & Carter, C.S (2003). A differential deficit in context processing associated with the genetic liability to schizophrenia: A sibling study. Archives of General Psychiatry, 60, 57-65. Barch, D.M., Carter, C.S, MacDonald, A.W., III, Braver, T.S., Cohen, J.D. (2003). Context processing deficits in schizophrenia: diagnostic specificity, four-week course, and relationship to clinical symptoms. Journal of Abnormal Psychology, 112, 132-143. MacDonald, A.W., III, & Carter, C.S. (2002). Cognitive experimental approaches to investigating impaired cognition in schizophrenia: a paradigm shift. Journal of Experimental and Clinical Neuropsychology, 24, 873-882. Carter, C.S., MacDonald, A.W., III, Ross, L.L., Stenger, V.A. (2001). Anterior cingulate cortex and impaired self-monitoring of performance in schizophrenia: an event-related fMRI study. American Journal of Psychiatry, 158, 1423-1428. MacDonald, A.W., III, Pogue-Geile, M.F., Debski, T.T., & Manuck, S. (2001). Genetic and environmental influences on schizotypy: A community-based twin study. Schizophrenia Bulletin,
  • 6. 6 27, 47-58. Barch, D.B., Carter, C.S., Sabb, F.W., MacDonald, A.W., III, Noll., D.C., Braver, T.S., & Cohen, J.D. (2001). Prefrontal cortex and context processing in medication naïve first episode patients with schizophrenia. Archives of General Psychiatry, 58, 280-288. MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (2000). Dissociating the role of the dorsolateral prefrontal cortex and anterior cingulate cortex in cognitive control. Science, 288, 1835-1838. Aizenstein, H.J., MacDonald, A.W., III, Stenger, V.A., Larson, J.K., Ursu, S., Nebes, R.D., Carter, C.S. (2000). Complementary category learning systems identified using event-related fMRI. Journal of Cognitive Neuroscience, 12, 977-987. Carter, C.S., MacDonald, A.W., III, Botvinick, M., Ross, L.L., Stenger, V.A., Noll, D. & Cohen, J.D. (2000). Parsing executive processes: strategic versus evaluative functions of the anterior cingulate cortex. Proceedings of the National Academy of Sciences, 97, 1944-1948. August, G.A., MacDonald, A.W., III, Realmuto, G.M., & Skare, S.S. (1996). Hyperactive and aggressive pathways: effects of demographic, family and child characteristics on children’s adaptive functioning. Journal of Clinical Child Psychology, 25, 341-351. August, G.A., Realmuto, G.M., MacDonald, A.W., III, Nugent, S.M., & Crosby, R. (1996). Prevalence of ADHD and comorbid disorders among elementary school children screened for disruptive behavior. Journal of Abnormal Child Psychology, 24, 571-595. August, G.A., Realmuto, G.M., Crosby, R.D., & MacDonald, A.W., III (1995). Community- based multiple-gate screening of children at-risk for conduct disorder. Journal of Abnormal Child Psychology, 23, 521-544. Harrow, M., MacDonald, A.W., III, Sands, J.R., & Silverstein, M.L. (1995). Vulnerability to delusions over time in schizophrenia, schizoaffective and bipolar and unipolar affective disorders: a multi-followup assessment. Schizophrenia Bulletin, 21, 95-109. Peer-reviewed Journal Articles in Submission MacDonald, A.W., III, Goghari, V.M., Hicks, B.M., Flory, J.D., Carter, C.S., Manuck, S.B. (in submission). Differential Deficits in Context Processing: Efficient Measurement and Relation to Neuropsychological Functioning. MacDonald, A.W., III, Becker, T.M., Pogue-Geile, M.F., & Carter, C.S. (under revision). Post- hoc True Score Variance Matching to Compare Working Memory Processes in Schizophrenia. Brambilla, P., MacDonald, A.W., III, Sassi, R.B., Johnson, M.K., Mallinger, A.G., Frank, E., Kupfer, D.J., Carter, C.S., & Soares, J.C. (in submission). Context processing performance in bipolar disorder patients. Invited Journal Articles & Chapters
  • 7. 7 MacDonald, A.W., III, & Iacono, W.G. (in press). Toward an integrated etiology of psychopathy. In C.J. Patrick (Ed.), Handbook of Psychopathy. New York: Guilford Press. Krueger, R.F., & MacDonald, A.W., III (2005). Dimensional approaches to understanding and treating psychosis. Psychiatric Annals. Special Issue on Comorbidity and Schizophrenia. 35, 31-35. Published Abstracts MacDonald, A.W., III, Johnson, M.K., Becker, T.M. & Carter, C.S. (2003). Context processing deficits associated with hypofrontality in the healthy relatives of schizophrenia patients: an event- related fMRI study. Schizophrenia Research, 60, 228. Carter, C.S., MacDonald, A.W., III, Holmes, A.J., & Stenger, V.A. (2003). Prospective longitudinal fMRI study of prefrontal cortex based context processing in never medicated first- episode schizophrenia. Schizophrenia Research, 60, 214. Snitz, B.E., MacDonald, A.W., III, & Carter, C.S. (2003). Cognitive impairments in adult first- degree relatives of schizophrenia patients: a meta-analytic review. Schizophrenia Research, 60, 158. Kerns, J.G., MacDonald, A.W., III, Barch, D.M., Holmes, A.J., Cohen, J.D. & Carter, C.S. (2003). Context processing deficits and decreased prefrontal cortex activity: specific associations with unmedicated, first-episode schizophrenia and with disorganization symptoms. Schizophrenia Research, 60, 228. Becker, T.M., MacDonald, A.W., III, Pogue-Geile, M.F., & Carter, C.S. (2003). Demonstration of a differential deficit: empirical validation of psychometric principles using schizophrenia patients’ performance on working memory tasks. Schizophrenia Research, 60, 165. Holmes, A.J., MacDonald, A.W., III, Carter, C.S., Barch, D.M., Stenger, V.A., & Cohen, J.D. (2003). The specificity of context processing deficits associated with hypofrontality in schizophrenic patients: an event-related fMRI study. Schizophrenia Research, 60, 222. Cho, R.Y., Cohen, J.D., van Veen, V., MacDonald, A.W., III, Kerns, J.G., Konecky, R., Belanger, C., & Carter, C.S. (2003). A multimodal examination of anterior cingulate cortex correlations from trial-to-trial performance impairments in schizophrenia. Schizophrenia Research, 60, 215. MacDonald, A.W., III, Stenger, V.A., & Carter, C.S. (2002). Prefrontal cortical dysfunction and context processing deficits in unmedicated first-episode schizophrenia patients and their unaffected relatives: an event-related fMRI study. Program No. 521.2. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. CD-ROM. Cho, R.Y, Cohen, J.D., van Veen, V., MacDonald, A.W., III, Kerns, J., Kriley, C. & Carter, C.S. (2002). Anterior cingulate correlates of trial-to-trial performance impairments in schizophrenia. Program No. 521.4. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. CD-ROM.
  • 8. 8 MacDonald, A.W., III, Pogue-Geile, M.F., & Carter, C.S. (2001). Differential deficits in selective attention and working memory processes in the siblings of patients with schizophrenia. Schizophrenia Research, 49, 73. Carter, C.S., Barch, D.M., MacDonald, A.W., III, Ursu, S. & Cohen, J.D. (2001). Prefrontal- related impairments in cognitive control are not specific to schizophrenia. Schizophrenia Research, 49, 175. MacDonald, A.W., III, Ross, L.L., Becker,, J., & Carter, C.S. (2000). Attentional control processes in DLPFC: domain specific or domain general? Society for Neuroscience Abstracts, v. 26, pt I, 550. Society for Neuroscience: Washington, D.C. Carter, C.S., MacDonald, A.W., III, Ursu, S., & Stenger, V.A. (2000). Functional specialization within the frontal-parietal network supporting executive control. Society for Neuroscience Abstracts, v. 26, pt I, 550. Society for Neuroscience: Washington, D.C. MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (2000). Functional double dissociation of dorsolateral prefrontal cortex and anterior cingulate cortex in cognitive control. Neuroimage, 11, S1. MacDonald, A.W., III, Pogue-Geile, M.F., Thompson, J.L., Ross, L.R., Allen, T., Johnson, M.K., Lollo, N.D., Marquetter, A.R., Yablonski, E.J., & Caster, C.S. (2000). Differential deficit in working memory, not attention, associated with liability to schizophrenia: a sibling study of the expectancy AX-CPT. Behavior Genetics, 30, 411. MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (2000). Dissociating control processes of dorsolateral prefrontal cortex and anterior cingulate cortex with fMRI and the Stroop task. Journal of Cognitive Neuroscience, suppl., 111. Barch, D.B., Carter, C.S., Sabb, F.W., MacDonald, A.W., III, Noll., D.C., Braver, T.S., & Cohen, J.D. (1999). Prefrontal cortex and context processing in medication naïve first episode patients with schizophrenia. Society for Neuroscience Abstracts, v. 25, pt I, 1289. Society for Neuroscience: Washington, D.C. Carter, C.S., MacDonald, A.W., III, Botvinick, M.M., Stenger, A., & Cohen, J.D. (1999). Anterior cingulate cortex and executive control: what is it really doing? Society for Neuroscience Abstracts, v. 25, pt II, 2168. Society for Neuroscience: Washington, D.C. Aizenstein, H.J., MacDonald, A.W., III, Stenger, V.A., Larson, J.K., Ursu, S., Nebes, R.D., Carter, C.S. (1999). Complementary category learning systems identified using event-related fMRI. Society for Neuroscience Abstracts, v. 25, pt I, 1289. Society for Neuroscience: Washington, D.C. Barch, D.M., Carter, C.S., MacDonald, A.W., III, Sabb, F.W., Noll, D., & Cohan, J.D. (1999). Prefrontal cortex and context processing in medication-naive first-episode patients with schizophrenia. Schizophrenia Research, 36, 217-218 Carter, C.S., Barch, D.B., MacDonald, A.W., III, Noll, D., Stenger, A. & Cohen, J.D. (1999). Anterior cingulate and cognitive disability in schizophrenia: an event-related fMRI study.
  • 9. 9 Schizophrenia Research, 36, 219-220. MacDonald, A.W., III, Perlstein, W.M., Chein, J., Feiz, J., Noll, D., & Carter, C.S. (1999). An fMRI study of individual differences in working memory capacity in the N-back task. Journal of Cognitive Neuroscience, suppl., 34. Carter, C.S., MacDonald, A.W., III, Stenger, A., Noll, D., Cohen, J.D. (1999). Event-related fMRI of strategic vs. evaluative functions of the anterior cingulate during cognition. Journal of Cognitive Neuroscience, suppl., 63. Ross, L.L., Barch, D.B., Cohen, J.D., MacDonald, A.W., III, Noll, D., Stenger, A., & Carter, C.S. (1999). Anterior cingulate cortex dysfunction and cognitive disability in schizophrenia. Journal of Cognitive Neuroscience, suppl., 62. Pogue-Geile, M.F., Ferrell, R., Deka, R., Debski, T.T., Hall, J., MacDonald, A.W., III, & Manuck, S.B. (1997). Neuropsychological functioning and dopamine D4 receptor polymorphisms: a twin and genetic association study. Neuropsychiatric Genetics, 74, 627. MacDonald, A.W., III, Pogue-Geile, M.F., Manuck, S.B., Debski, T.T. (1996). Schizotypy and neuropsychological functioning: multivariate structure in twins. Behavior Genetics, 26, 591. Harrow, M., MacDonald, A.W., III, Sands, J.R., & Silverstein, M.L. (1993). Vulnerability to delusions and hallucinations in schizophrenia and affective disorders. Proceedings of the 101st Annual Meeting of the American Psychological Association. American Psychological Association: Washington, D.C. Harrow, M., Andres, B., MacDonald, A.W., III, Silverstein, M.L., & Sands, J. (1992) Delusions and hallucinations: schizophrenic traits? Proceedings of the 145th Annual Meeting of the American Psychiatric Association, 82. American Psychiatric Association: Washington, D.C. Other Publications MacDonald, A.W., III. (1995, May). Green passage beyond human words. Shambala Sun, 22-27. PRESENTATIONS MacDonald, A.W., III, Johnson, M.K., & Rusticini, A. (April 2005). Effects of paranoid- spectrum personality on social decision-making. Poster to be presented at the 10th Biennial International Congress of Schizophrenia Research, Savanna, Georgia. Haut, K. & MacDonald, A.W., III (April 2005). Persecutory delusions and the perception of trustworthy faces in schizophrenia. Poster to be presented at the 10th Biennial International Congress of Schizophrenia Research, Savanna, Georgia. Goghari, V., Rehm, K., Carter, C.S. & MacDonald, A.W., III (April 2005). MRI of prefrontal cortex in the healthy relatives of schizophrenia patients and controls. Poster to be presented at the 10th Biennial International Congress of Schizophrenia Research, Savanna, Georgia.
  • 10. 10 Laes, J., Sponheim, S.R. & MacDonald, A.W., III (April 2005). Relationships between cognitive functions and current social functioning in schizophrenia and bipolar affective disorder. Poster to be presented at the 10th Biennial International Congress of Schizophrenia Research, Savanna, Georgia. MacDonald, A.W., III, Johnson, M.K., Rusticini, A. (October, 2004). Game Theoretical Indicators of Paranoid Personality. Poster to be presented at the 19th Annual Meetings of the Society for Research in Psychopathology, St. Louis, Missouri. MacDonald, A.W., III, Johnson, M.K., Becker, T.M. & Carter, C.S. (April 2003). Context processing deficits associated with hypofrontality in the healthy relatives of schizophrenia patients: an event-related fMRI study. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Carter, C.S., MacDonald, A.W., III, Holmes, A.J., & Stenger, V.A. (April 2003). Prospective longitudinal fMRI study of prefrontal cortex based context processing in never medicated first- episode schizophrenia. Presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Snitz, B.E., MacDonald, A.W., III, & Carter, C.S. (April 2003). Cognitive impairments in adult first-degree relatives of schizophrenia patients: a meta-analytic review. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Kerns, J.G., MacDonald, A.W., III, Barch, D.M., Holmes, A.J., Cohen, J.D. & Carter, C.S. (April, 2003). Context processing deficits and decreased prefrontal cortex activity: specific associations with unmedicated, first-episode schizophrenia and with disorganization symptoms. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Becker, T.M., MacDonald, A.W., III, Pogue-Geile, M.F., & Carter, C.S. (April 2003). Demonstration of a differential deficit: empirical validation of psychometric principles using schizophreni patients’ performance on working memory tasks. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Holmes, A.J., MacDonald, A.W., III, Carter, C.S., Barch, D.M., Stenger, V.A., & Cohen, J.D. (April 2003). The specificity of context processing deficits associated with hypofrontality in schizophrenic patients: an event-related fMRI study. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. Cho, R.Y., Cohen, J.D., van Veen, V., MacDonald, A.W., III, Kerns, J.G., Konecky, R., Belanger, C., & Carter, C.S. (April 2003). A multimodal examination of anterior cingulate cortex correlations from trial-to-trial performance impairments in schizophrenia. Poster presented at the 9th Biennial International Congress of Schizophrenia Research, Colorado Springs, CO. MacDonald, A.W., III, Stenger, V.A., & Carter, C.S. (November 2002). Prefrontal cortical dysfunction and context processing deficits in unmedicated first-episode schizophrenia patients and their unaffected relatives: an event-related fMRI study. Presented at the 32nd Annual Meeting of the Society for Neuroscience, Orlando, FL.
  • 11. 11 Cho, R.Y, Cohen, J.D., van Veen, V., MacDonald, A.W., III, Kerns, J., Kriley, C. & Carter, C.S. (November 2002). Anterior cingulate correlates of trial-to-trial performance impairments in schizophrenia. Presented at the 32nd Annual Meeting of the Society for Neuroscience, Orlando, FL. MacDonald, A.W., III, Pogue-Geile, M.F., Johnson, M.K. & Carter, C.S. (November 2001). Context processing in the unaffected siblings of patients with schizophrenia: Test of a differential deficit. Poster presented at the 16th Annual Meetings of the Society for Research in Psychopathology, Madison, Wisconsin. Smadar Levin Award, Runner-up. MacDonald, A.W., III, Pogue-Geile, M.F., & Carter, C.S. (April 2001). Differential deficits in selective attention and working memory processes in the siblings of patients with schizophrenia. Poster presented at the Eighth Biennial Meeting of the International Congress on Schizophreni Research, Whistler, British Columbia, Canada. Carter, C.S., Barch, D.M., MacDonald, A.W., III, Ursu, S. & Cohen, J.D. (April 2001). Prefrontal-related impairments in cognitive control are not specific to schizophrenia. Presented at the Eighth Biennial Meeting of the International Congress on Schizophreni Research, Whistler, British Columbia, Canada. MacDonald, A.W., III, Ross, L.L., Becker,, J., & Carter, C.S. (November 2000). Attentional control processes in DLPFC: domain specific or domain general? Presented at the 30th Annual Meeting of the Society for Neuroscience, New Orleans, LA. Carter, C.S., MacDonald, A.W., III, Ursu, S., & Stenger, V.A. (November 2000). Functional specialization within the frontal-parietal network supporting executive control. Presented at the 30th Annual Meeting of the Society for Neuroscience, New Orleans, LA. MacDonald, A.W., III, Pogue-Geile, M.F., Thompson, J.L., Ross, L.L., Allen, T., Johnson, M.K., Lollo, N.D., Marquette, A.R., Yablonsky, E.J., Carter, C.S. (June 2000). Differential deficit in working memory, not attention, associated with liability to schizophrenia: a sibling study of the expectancy AX-CPT. Presented at the 30th Annual Meeting of the Behavior Genetics Association, Burlington, VT. MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (June 2000). Functional double dissociation of dorsolateral prefrontal cortex and anterior cingulate cortex in cognitive control. Presented at the 6th Annual Meeting of the Society for Human Brain Mapping, San Antonio, TX. MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (April 2000). Dissociating control processes of dorsolateral prefronal cortex and anterioir cingulate cortex with fMRI and the Stroop task. Poster presented at the Annual Meeting of the Cognitive Neuroscience Society, San Francisco, CA. Barch, D.B., Carter, C.S., Sabb, F.W., MacDonald, A.W., III, Noll., D.C., Braver, T.S., & Cohen, J.D. (October 1999). Prefrontal cortex and context processing in medication naïve first episode patients with schizophrenia. Presented at the 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FL.
  • 12. 12 Carter, C.S., MacDonald, A.W., III, Botvinick, M.M., Stenger, A., & Cohen, J.D. (October 1999). Anterior cingulate cortex and executive control: what is it really doing? Poster presented at the 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FL. Aizenstein, H.J., MacDonald, A.W., III, Stenger, V.A., Larson, J.K., Ursu, S., Nebes, R.D., Carter, C.S. (October 1999). Complementary category learning systems identified using event- related fMRI. Presented at the 29th Annual Meeting of the Society for Neuroscience, Miami Beach, FL. Carter, C.S., MacDonald, A.W., III, Stenger, A., Noll, D. & Cohen, J.D. (May 1999). Strategic versus evaluative functions of the anterior cingulate during cognition. Presented at the Annual Meeting of the Society of Biological Psychiatry. Washington, D.C. Carter, C.S., Barch, D.B., MacDonald, A.W., III, Ross, L.L., Noll, D., Stenger, A. & Cohen, J.D. (May 1999). Anterior cingulate cortex and cognitive disability in schizophrenia. Presented at the Annual Meeting of the Society of Biological Psychiatry. Washington, D.C. Barch, D.M., Carter, C.S., MacDonald, A.W., III, Sabb, F.W., Noll, D., & Cohan, J.D. (April 1999). Prefrontal cortex and context processing in medication-naive first-episode patients with schizophrenia. Presented at the 7th International Congress on Schizophrenia Research. Santa Fe, NM. Carter, C.S., Barch, D.B., MacDonald, A.W., III, Noll, D., Stenger, A. & Cohen, J.D. (April 1999). Anterior cingulate and cognitive disability in schizophrenia: an event-related fMRI study. Presented at the 7th International Congress on Schizophrenia Research. Santa Fe, NM. MacDonald, A.W., III, Perlstein, W.M., Chein, J., Feiz, J., Noll, D., & Carter, C.S. (April 1999). An fMRI study of individual differences in working memory capacity in the N-back task. Poster presented at the Cognitive Neuroscience Society Annual Meeting. Washington, D.C. Carter, C.S., MacDonald, A.W., III, Stenger, A., Noll, D., Cohen, J.D. (April 1999). Event- related fMRI of strategic vs. evaluative functions of the anterior cingulate during cognition. Poster presented at the Cognitive Neuroscience Society Annual Meeting. Washington, D.C. Ross, L.L., Barch, D.B., Cohen, J.D., MacDoanld, A.W., III, Noll, D., Stenger, A., & Carter, C.S. (April 1999). Anterior cingulate cortex dysfunction and cognitive disability in schizophrenia. Poster presented at the Cognitive Neuroscience Society Annual Meeting. Washington, D.C. MacDonald, A.W., III, Pogue-Geile, M.F., & Gaulin, S. (November 1998). Population genetic perspectives on the persistence of schizophrenia. Poster presented at the 13th Annual Meeting of the Society for Research in Psychopathology. Cambridge, MA. Lourea, B., Pogue-Geile, M.F. & MacDonald, A.W., III (November 1998). Genetic liability to schizophrenia and dopamine activity: a family study of schizophrenia and eye-blink rate. Poster presented at the 13th Annual Meeting of the Society for Research in Psychopathology. Cambridge, MA. Pogue-Geile, M., Ferrell, R., Deka, R., Debski, T., Hall, J., MacDonald, A.W., III, & Manuck, S. (November 1998). Cognitive functioning and dopamine D4 receptor polymorphisms: A twin and
  • 13. 13 genetic association study. Poster presented at the 13th Annual Meeting of the Society for Research in Psychopathology. Cambridge, MA. MacDonald, A.W., III, & Pogue-Geile, M.F. (July 1998). Models of the persistence of genetic variability and the transmission of risk for schizophrenia. Poster presented at the 10th Annual Meeting of the Human Behavior and Evolution Society. Davis, CA. Pogue-Geile, M.F., Ferrell, R., Deka, R., Debski, T.T., Hall, J., MacDonald, A.W., III, & Manuck, S.B. (October 1997). Neuropsychological functioning and dopamine D4 receptor polymorphisms: a twin and genetic association study. Presented at the World Congress of Psychiatric Genetics. Santa Fe, New Mexico. MacDonald, A.W., III, Pogue-Geile, M.F., Manuck, S.B., & Debski, T.T. (September 1996). Is schizotypy related to neuropsychological deficits? A multivariate analysis in twins. Poster presented at the 11th Annual Meeting of the Society for Research in Psychopathology. Atlanta, GA. MacDonald, A.W., III, Pogue-Geile, M.F., Manuck, S.B., Debski, T.T. (June 1996). Schizotypy and neuropsychological functioning: multivariate structure in twins. Poster presented at the 26th annual meeting of the Behavior Genetics Association. Pittsburgh, PA. MacDonald, A.W., III, Skare, S.S., & August, G.A. (April 1995). Early hyperactive versus aggressive behavior: a comparison of the risks to prosocial functioning. Poster presented at the Biennial Meeting of the Society for Research in Child Development, Indianapolis, IN. MacDonald, A.W., III, & Harrow, M. (May 1994). Prognostic significance of delusions and hallucinations in schizophrenia and affective disorders. Presented at the 66th Annual Meeting of the Midwest Psychological Association, Chicago, IL. MacDonald, A.W., III, Frazer, M., August, G.A., & Realmuto, G.M. (April 1994). Family protective factors associated with socio-emotional adjustment in children with behavior problems. Presented at the 2nd Annual Research Symposium on Child and Family Issues, Fargo, ND. Harrow, M., MacDonald, A.W., III, Sands, J.R., & Silverstein, M.L. (August 1993). Vulnerability to delusions and hallucinations in schizophrenia and affective disorders. Presented at the 101st Annual Meeting of the American Psychological Association, Toronto, ON, Canada. Harrow, M., MacDonald, A.W., III, Butz, C., Sands J.R., & Silverstein, M.L. (November 1992). Bipolar and unipolar affective disorders: vulnerability to subsequent delusions. Presented at the 7th Annual Meeting of the Society for Research in Psychopathology, Palm Springs, CA. Harrow, M., Andres, B., MacDonald, A.W., III, Silverstein, M.L., & Sands, J. (October, 1992) Delusions and hallucinations: schizophrenic traits? Presented at the 145th Annual Meeting of the American Psychiatric Association, San Francisco, CA. PROFESSIONAL ACTIVITIES Journal Reviewing:
  • 14. 14 1. Consulting Editor: Journal of Abnormal Psychology (2005-2006) 2. Ad Hoc Referee: Archives of General Psychiatry (2003 – 2005), Biological Psychiatry (2004), BioMed Central (BMC) Psychiatry (2004), Bipolar Disorder (2002), Brain and Behavioral Science (2002), Cerebral Cortex (2003-2004), Journal of Abnormal Psychology (1999 – 2004), Neuroimage (2002, 2004), Neuropsychology (2005), Psychological Medicine (2004), Psychiatry Research (2003), Schizophrenia Research (2004). Grant Reviewing: National Institute of Mental Health, Special Emphasis Panel ZMH1 NRB-Q, Member, 2004 – 2005 University of Minnesota Medical Center, General Clinical Research Center, Referee, 2005 Wellcome Trust, External Reviewer, 2004 Western Psychiatric Institute & Clinic, Research Committee Referee, 2000-2002 Graduate Student Mentoring: 1. Vina Goghari, 2003-present. University of Minnesota Department of Psychology, Clinical Science and Psychopathology Research Program. a. Graduate Research Partnership Program project “Prefrontal structure and function in the healthy relatives of schizophrenia patients and controls”, 2004. b. NSERC Master’s Award, “Comparison of neuroanatomical basis of cognitive control and response inhibition”, 2004-2005. c. NSERC Doctoral Award, “”, 2005-2008. 2. Sandra Alcala, 2003-2004. University of Minnesota Graduate Program in Neuroscience. 3. Kristen Haut, 2004-present. University of Minnesota Department of Psychology, Clinical Science and Psychopathology Research Program. a. Graduate Research Partnership Program project “”, 2005. 4. Seung Suk Kang, 2004-present. University of Minnesota Department of Psychology, Biological Psychopathology Program, Co-Advisor with S.R. Sponheim. 5. Rachel Force, 2004-present. University of Minnesota Department of Psychology, Biological Psychopathology Program, Co-Advisor with S.R. Sponheim. Undergraduate Student Mentoring: 19 University of Minnesota Directed Research advisees (2003-present) 14 University of Pittsburgh Directed Research advisees (1998-2002) 1. Theresa M. Becker, 2002, University of Pittsburgh Senior Honors Thesis, “Verbal & Spatial Working Memory Deficits in Schizophrenia Patients: General of Specific?” 2. Jessica L. Barker, 2003, University of Minnesota, Undergraduate Research Partnership Program Grant. 3. Kyle Ratner, 2003, Research Experience for Undergraduates Summer Program, “Cognitive Components of Economic Decision-Making.” 4. Marsha Sargeant, 2004, Research Experience for Undergraduates Summer Program, “Personality Correlates of Antisocial Behavior in Economic Decision-Making Games.” Thesis Committee Service: 1. Doctoral Theses a. Elizabeth Hurliman (CSPR). “Feedback processing in the vental prefrontal lobes,” Defended November 2004. 2. Comprehensive Specials Theses
  • 15. 15 a. Stephen Benning (CSPR). Defended September 2004. 3. Undergraduate Honors Theses a. JoAn Laes (Psychology). “Relationships between cognitive functions and current social functioning in schizophrenia and bipolar affective disorder,” Defended April 2004. Courses Taught: 1. Psychology 4993/8993: Neuroimaging and Psychopathology (Research Seminar). Spring, Summer & Fall 2003; Spring, Summer & Fall 2004. 2. Psychology 8814 : Analysis of Psychological Data (Psychology Graduate Core Curriculum). Fall 2003, Fall 2004. 3. Psychology 8622: Treatment of Mental Disorders (Clinical Psychology and Psychopathology Research Program Required course). Fall 2003, Fall 2004. 4. Psychology 8960: Neuroimaging: Methods and Applications (Graduate Research Seminar). Spring 2004. 5. Guest Lectures: a. Psychology 5061: Behavioral Neuroscience. Instructor: Jonathan Gewirtz. Spring 2004. Topic: Neuroscience of Schizophrenia. b. Neuroscience 5661: Behavioral Neuroscience. Instructor: Karen Mesce. Spring 2004. Topic(s): Functional Neuroimaging, Neuroscience of Cognitive Control. Academic Service: 1. College of Liberal Arts Assembly Representative, 2004. 2. Psychology Department, Computer and Equipment Facilities Committee, 2004. 3. Psychology Department, MRI Users’ Group, Faculty Supervisor, 2004. Other Academic Service / Volunteer Activities: 1. Society for Research in Psychopathology, Chair, Website Development & Oversight Committee, 2004-2006. 2. Society for Neuroscience, Community Presenter, Brain Awareness Week, 2004. 3. National Alliance for Mentally Ill, Annual Research Dinner, Presenter, 2005.