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Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
Lecture 7
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Lecture 7

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  • 1. Lecture 7 BIOL L100 Indiana University Southeast David Partin, Instructor
  • 2. Today’s Agenda <ul><li>Announcements/Questions </li></ul><ul><li>Lecture 7: Mendelian Genetics and beyond </li></ul><ul><li>Practice Punnett Squares </li></ul><ul><li>One Minute Paper </li></ul><ul><li>Lab </li></ul><ul><li>Introduce Case Study #1 </li></ul>
  • 3. Chapter 11 <ul><li>Mendelian Genetics (and beyond) </li></ul>
  • 4. <ul><li>Gregor Mendel: </li></ul><ul><li>Austrian monk </li></ul><ul><li>Scientist </li></ul><ul><li>Pea farmer </li></ul><ul><li>Snazzy dresser </li></ul>
  • 5. Most traits are inherited independently. Mendel’s experiments refuted the “blending” concept of inheritance.
  • 6. Genotype- Phenotype- Homozygous- Heterozygous-
  • 7. Punnett Square Capital letters are always used to represent dominant traits. Dominant trait- Recessive trait-
  • 8. Alleles -alternate forms of a gene. Locus -alleles can be found on homologous chromosomes at a particular location called a gene locus.
  • 9. Let’s draw both parents’ chromosomes to make this concept clearer.
  • 10. Phenotype of offspring can reveal genotype of parents.
  • 11. Connection: Mendel’s Laws and Meiosis Instead of 1 trait at a time, let’s look at how 2 traits can be passed together.
  • 12. Dihybrid cross- Could you draw the parents’ chromosomes? Homozygous dominant Homozygous recessive
  • 13. &nbsp;
  • 14. Heterozygous for both traits Homozygous recessive
  • 15. Let’s take a break… <ul><li>Thanks for your attention! </li></ul><ul><li>When we return: </li></ul><ul><ul><li>Human pedigrees </li></ul></ul><ul><ul><li>Beyond Mendelian Genetics </li></ul></ul>
  • 16. Obviously, it wouldn’t be ethical to do ‘test-crosses’ on humans! We record human genetic information in a pedigree . KEY Square- Circle- Shaded- Unshaded- Horizontal line- Vertical line-
  • 17. Examples: Tay-Sachs Disease, Cystic Fibrosis, Phenylketonuria (PKU)
  • 18. Huntington Disease and Neurofibromatosis, for example
  • 19. Incomplete Dominance-
  • 20. Co-Dominance- Multiple alleles-
  • 21. Polygenic inheritance-
  • 22. &nbsp;
  • 23. Environmental effects on genetics
  • 24. Any questions?
  • 25. Take a short break if you need one! <ul><li>What’s next? </li></ul><ul><li>Practice Punnett Squares </li></ul><ul><li>One-Minute Paper </li></ul><ul><li>Lab </li></ul><ul><li>Introduce Case Study #1 </li></ul>
  • 26. Punnett Squares <ul><li>Let’s do some practice problems… </li></ul>
  • 27. Overview of today’s lab <ul><li>In this exercise, you will observe and record the results of the offspring produced in a dihybrid heterozygous cross of two corn phenotypes. </li></ul><ul><li>The corn kernel phenotypes are: </li></ul><ul><ul><li>Purple &amp; starchy (purple &amp; nonwrinkled) </li></ul></ul><ul><ul><li>Purple &amp; sweet (purple &amp; wrinkled) </li></ul></ul><ul><ul><li>Yellow &amp; starchy (yellow &amp; nonwrinkled) </li></ul></ul><ul><ul><li>Yellow &amp; sweet (yellow &amp; wrinkled) </li></ul></ul><ul><li>Each team will count 3 ears of corn &amp; record the total number of each type of kernel. Don’t remove the kernels. Use pins to mark the counted rows. </li></ul><ul><li>Record your results &amp; answer the questions on pp55-56. </li></ul><ul><li>It could be useful to work through some of the questions at the end of Ch11 (pp201-202) and the “Practice Problems” found throughout the chapter. They won’t be turned in or graded, but some questions on the exam may look similar… </li></ul>
  • 28. Case Study #1 <ul><li>“ Sometimes it IS all in the Genes” </li></ul><ul><li>Mendelian genetics, Punnett squares </li></ul><ul><li>Cystic fibrosis: autosomal recessive disorder </li></ul>
  • 29. Preparation for Lecture 8 <ul><li>Study today’s lecture materials (and Ch. 11 &amp; 12), so that Lecture 8 will be more useful to you. </li></ul><ul><li>Read Ch. 13 </li></ul>

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