Lecture 7
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Lecture 7

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    Lecture 7 Lecture 7 Presentation Transcript

    • Lecture 7 BIOL L100 Indiana University Southeast David Partin, Instructor
    • Today’s Agenda
      • Announcements/Questions
      • Lecture 7: Mendelian Genetics and beyond
      • Practice Punnett Squares
      • One Minute Paper
      • Lab
      • Introduce Case Study #1
    • Chapter 11
      • Mendelian Genetics (and beyond)
      • Gregor Mendel:
      • Austrian monk
      • Scientist
      • Pea farmer
      • Snazzy dresser
    • Most traits are inherited independently. Mendel’s experiments refuted the “blending” concept of inheritance.
    • Genotype- Phenotype- Homozygous- Heterozygous-
    • Punnett Square Capital letters are always used to represent dominant traits. Dominant trait- Recessive trait-
    • Alleles -alternate forms of a gene. Locus -alleles can be found on homologous chromosomes at a particular location called a gene locus.
    • Let’s draw both parents’ chromosomes to make this concept clearer.
    • Phenotype of offspring can reveal genotype of parents.
    • Connection: Mendel’s Laws and Meiosis Instead of 1 trait at a time, let’s look at how 2 traits can be passed together.
    • Dihybrid cross- Could you draw the parents’ chromosomes? Homozygous dominant Homozygous recessive
    •  
    • Heterozygous for both traits Homozygous recessive
    • Let’s take a break…
      • Thanks for your attention!
      • When we return:
        • Human pedigrees
        • Beyond Mendelian Genetics
    • Obviously, it wouldn’t be ethical to do ‘test-crosses’ on humans! We record human genetic information in a pedigree . KEY Square- Circle- Shaded- Unshaded- Horizontal line- Vertical line-
    • Examples: Tay-Sachs Disease, Cystic Fibrosis, Phenylketonuria (PKU)
    • Huntington Disease and Neurofibromatosis, for example
    • Incomplete Dominance-
    • Co-Dominance- Multiple alleles-
    • Polygenic inheritance-
    •  
    • Environmental effects on genetics
    • Any questions?
    • Take a short break if you need one!
      • What’s next?
      • Practice Punnett Squares
      • One-Minute Paper
      • Lab
      • Introduce Case Study #1
    • Punnett Squares
      • Let’s do some practice problems…
    • Overview of today’s lab
      • In this exercise, you will observe and record the results of the offspring produced in a dihybrid heterozygous cross of two corn phenotypes.
      • The corn kernel phenotypes are:
        • Purple & starchy (purple & nonwrinkled)
        • Purple & sweet (purple & wrinkled)
        • Yellow & starchy (yellow & nonwrinkled)
        • Yellow & sweet (yellow & wrinkled)
      • Each team will count 3 ears of corn & record the total number of each type of kernel. Don’t remove the kernels. Use pins to mark the counted rows.
      • Record your results & answer the questions on pp55-56.
      • It could be useful to work through some of the questions at the end of Ch11 (pp201-202) and the “Practice Problems” found throughout the chapter. They won’t be turned in or graded, but some questions on the exam may look similar…
    • Case Study #1
      • “ Sometimes it IS all in the Genes”
      • Mendelian genetics, Punnett squares
      • Cystic fibrosis: autosomal recessive disorder
    • Preparation for Lecture 8
      • Study today’s lecture materials (and Ch. 11 & 12), so that Lecture 8 will be more useful to you.
      • Read Ch. 13