Genetics in Primary Care (GPC) A Faculty Development Initiative The GPC is a 3 year contract funded by: Maternal and Child Health Bureau Bureau of Health Professions H.R.S.A. Co-funded by the Nat’l Human Genome Proj. Research Institute Agency for Healthcare Research and Quality N.I.H.
Our lives are being approached by waves of new genetic information and technology.
These waves are getting bigger and making more of an impact on our lives. Just consider the rapid developments in genetics over its brief history…
The manipulation of biologic matter, such as DNA, for commercial uses.
“ We are only on the threshold of discovery, at about the same stage that computer technology developers were in the 1950s. But the potential of biotechnology is almost unimaginable.” Richard W. Oliver
Caroline: 20 year old who just found out she is pregnant. The man she suspects is the father was killed in an automobile accident. He was cremated at the request of his parents. He had social security benefits which may be used to support this child if paternity is confirmed.
Is it possible to establish paternity in this case without any sample from the father?
S GF X C X GM M R Parentage testing: reconstruction of a deceased alleged father’s DNA profile by testing his parents S = size GF = alleged father’s father GM = alleged father’s mother C = child M = mother R = control DNA X = mixed DNA, child with GF, child with GM = Paternal contribution = Maternal contribution
Adult stem cells are descendents of embryonic stem cells, & different types have been found in different tissues, such as skin, fat, breast, blood, lung and brain. These types of stem cells stay in the body for decades.
The blood stem cells can divide & make more blood stem cells as well as the different types of blood cells like red, white and platelets. Recently scientists found that some adult stem cells may form other tissue types .
On Aug. 9, 2001, President Bush decided that federal funds can be used to support stem cell research. However, it is limited to work on the approximately 60 cell lines that were developed before the announcement.
Currently there is much debate about the limits this announcement places on research in the U.S.
The “Genetic Wave” is building. We can let it pass us by, be overwhelmed by it, or benefit from its energy like a surfer.
Given the right environment, embryonic stem cells can become any one of many different types of tissue. Recently Dr. George Daley & his team of researchers at the Whitehead Institute found a way to transform those cells into egg-like cells.
Using genetic engineering, Dr. Daley’s team caused embryonic stem cells from mice to grow into structures that resembled early embryos. In these structures, the researchers found & isolated the egg & sperm cells that combine to create embryos.
The team them allowed the egg cells to grow & develop into cells that resembled natural egg cells. The next step for the researchers involves experiments to determine whether the egg-like cells have exactly the same biological properties as natural produced egg cells.