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    GENETICS at georgia GENETICS at georgia Document Transcript

    • GENETICS at georgia Spring 2007 volume 3 • department of genetics • www.genetics.uga.edu • university of georgia, athens Roger Deal awarded 06-07 Genetics faculty recognized Shannon Yu receives Bishop fellowship for research and creativity Kenyon award The first recipient of the Linton and Robert Ivarie and Richard Meagher were Shannon Yu received the Cynthia Ken- June Bishop Graduate Fellowship in recognized for outstanding research and yon Undergraduate Award at the third Genetics is Roger Deal, a graduate student creativity at the UGA 28th annual Re- annual undergraduate spring symposium. in Rich Meagher’s lab. The fellowship, search Awards Banquet. The Kenyon award, named in honor of a which recognizes the accomplishments Ivarie received the Inventor’s Award former undergradu- of a senior genetics graduate student for a number of inventions and novel ate now on the each year, was methods to genetically engineer chickens faculty of the Uni- established by a as bioreactors for the low-cost produc- versity of Califor- generous gift of Dr. tion of proteins that have therapeutic po- nia-San Francisco, Linton and Mrs. tential for humans. His work lead to the is given each year to June Bishop. founding of Avigenics, Inc., a biotechnol- an outstanding un- Deal’s graduate ogy company located in Athens. dergraduate student work focuses Meagher was named a Distinguished for exceptional per- on chromatin Research Professor in recognition of his formance in academics, in research, and modification, an outstanding national and international in leadership outside of the classroom. important aspect of gene expression research and creative achievements. He Shannon’s work centers on an analy- in all higher organisms. His thesis was the first scientist to engineer plants sis of the parathyroid phenotypes of examines how nuclear actin related to take up toxins from the soil, a field tissue-specific knockouts of the Sonic proteins function in histone modification now known as phytoremediation. In ad- Hedgehog signaling pathway in the lab of in the plant Arabidopsis. Roger plans dition, he established himself as a leading Nancy Manley. She will enter the PhD to begin postdoctoral work at the Fred authority on the plant cytoskeleton and program at Sloan Kettering Cancer Cen- Hutchinson Cancer Research Center in on monoclonal antibody production. ter in New York City next fall. Seattle in the fall of 2007. Norman H. Giles, 1915 - 2006 Alton fellows named Chih-Horng Kuo and Jodie Linder O n October 16, 2006, Norman H. Giles, the Fuller E. Cal- laway Emeritus Professor of Genetics at the University of Georgia, passed away in his sleep at the age of 91, following com- have received the Kirby and Jan Alton plications from a fall. It would be difficult to overstate the impact Graduate Fellowship for 06-07 and 07- of his life and career on the Genetics Department and the Uni- 08, respectively. The versity of Georgia. Norman was an international leader in the field of Genetics, a great Alton fellowship, scientist, and an intellectual with broad based knowledge beyond science—someone for funded by a generous whom the term Renaissance man truly applied. continuing gift from A native of Atlanta, Norman earned his A.B. in Biology from Emory University before Dr. Kirby (Ph.D. moving to Harvard where he completed his Ph.D. in 1940. His dissertation focused on ‘81) and Jan Alton, the nature of spontaneous and induced chromosomal mutations and genome rearrange- provides full support ments in plants. He then joined the faculty at Yale University in 1941 where he rose for an outstanding through the ranks, becoming Professor of Biology in 1951 and Eugene Higgins Professor fourth year graduate of Genetics in 1961. In the 1940s, Norman began research on the fungus Neurospora student each year. crassa and during the ensuing 35 years made many fundamental contributions to the mo- Kuo, who is co- lecular genetic analysis of biochemical pathways and the ways in which genes influence advised by Jessica metabolism. For example, using X-ray induced mutations he showed that back mutations Kissinger and Daniel (or reversions) identify new genes that encode proteins in the same pathway, and he sys- Promislow, studies tematically deduced entire metabolic pathways in Neurospora. This seminal work set the stage for elucidating much of what we now understand about biosynthetic and catabolic see Alton on page 6 see Giles on page 4
    • vol 3 spring 2007 2 Editor’s note NEWS ¦ Graduate Program It has been a great pleasure to edit the first three volumes T he 2006-2007 academic year was another banner year for the Genetics graduate program. Our students continued won the 2006-2007 UGA Outstanding Teaching Assistant Award in recognition of her teaching of Genetics at to excel, making significant contributions accomplishments. georgia, in large by publishing in top-tier journals such Lastly, Genetics part because of as Science, the Journal of Bacteriology, graduate students the enthusiastic Molecular Biology and Evolution, BMC were recognized response to our Genomics, Proceedings of the Royal Society, for their important annual solicitation of alumni news. We and Plant Cell. Several articles authored leadership roles in take great pride in the accomplishments by Genetics students were highlighted the UGA community of our 350 undergraduate and 200 Rebecca as noteworthy articles in Science and on this past year – graduate alumni and are pleased to Faculty of 1000. Additionally, several Rebecca Tomlinson and Jeremy DeBarry have heard from many of you. Please students were invited to present their were selected to participate in the UGA help us by continuing to send news of research at platform and poster sessions Graduate Future Leaders Program, and your current occupation or career or at national and international research Vanessa Corby-Harris personal milestones to Susan White conferences. Brunie Brugos, a first year was elected to the Blue (whites@uga.edu) for publication in student, was selected to speak at the 8th Key National Honor next year’s issue. Annual Plant Science Center Retreat at Society. I am also very grateful for your gifts Lake Lanier last fall, and in recognition of Finally, it is to the Genetics department. This his contributions, Roger Deal was awarded important to recognize year, thanks to your generosity, the a Graduate Research those students who newly established Genetics Alumni Recognition Award at have recently joined Student Travel Fund made two awards the 17th International Jeremy our program and to support student travel to research Conference on those that graduated this academic year. conferences. Vanessa Corby-Harris, a Arabidopsis Research. The Department was excited to welcome graduate student in Daniel Promislow’s The Genetics seven new students into our family. In lab, presented her research on the Department graduate addition, we congratulate our most recent relationship between immunity and Brunie students received graduate, Roger Deal, and those students microbial community richness in natural numerous awards for preparing to graduate this August, populations of Drosophila melanogaster their research, leadership, and teaching including Rebecca Tomlinson, Zhijie in a talk at the 48th Annual Drosophila accomplishments in 2006. As a testament ( Jason) Liu, and Vanessa Corby-Harris. Research Conference in Philadelphia to their creativity and scientific rigor, eight We are proud that they will be occupying in March of 2007. Shannon Yu, an graduate students received research grants postdoctoral positions in many of the undergraduate in Nancy Manley’s lab, and fellowships. Monica Poelchau, a third country’s top research labs. Roger Deal will present her work on the role year student, was awarded an Organization moves to Seattle, Washington, this spring of sonic hedgehog signaling during for Tropical Studies Research Fellowship to begin work with Steve Henikoff at parathyroid organogenesis in the mouse to conduct her fieldwork last summer the Fred Hutchinson Cancer Research at the Society for Developmental in Central America. Chih-Horng Kuo Center. Also, Vanessa Corby-Harris Biology meeting being held in Cancun, received both the James L. Carmon was awarded a postdoctoral fellowship Mexico in June 2007. Information Honorarium for his innovative use of through the University of Arizona’s about how to make a gift to this and computers in his dissertation research, Center for Insect Science and will begin other Genetics department funds can and the second annual Kirby and Jan working with Teri Markow this fall. be found on the inside back page of the Alton Graduate Research Fellowship. With the incoming class of graduate newsletter. Eve Basenko and Jodie Linder, both third students on their way, our junior students Michael Bender year students, received Sigma Xi grants kicking their research projects into high for their research. Roger Deal, who is gear, and several students preparing for in his final year, was given a Dissertation December and May graduation dates, Completion Award and was the first the Genetics graduate program promises PLEASE VISIT OUR WEB Genetics graduate student to receive to continue its tradition of productivity, SITE AT the prestigious Linton and June Bishop leadership, and vibrancy through 2007 www.genetics.uga.edu Graduate Fellowship. Our students’ and into 2008. continued commitment to teaching was Vanessa Corby-Harris exemplified by Nandita Mullapudi, who
    • Genetics at georgia 3 ‘Ticking timekeepers’ Head’s note Researchers publish first working model that explains how biological clocks work This has been a bit- tersweet year in By Philip Lee Williams the Department of Genetics. We were S cience has known for decades that biological clocks govern the behavior of saddened by the everything from humans to bread mold. These ticking timekeepers hold the key to death in October of many diseases, annoy passengers on intercontinental flights and can mean life or death Dr. Norman Giles, for small creatures trying to survive in nature. the founder of the Despite the importance of biological clocks, their mechanisms Genetics program at UGA (see article on have remained unclear. Now, a team of researchers from the p. 1). Norman was an extraordinary sci- University of Georgia has produced the first working model that entist and a true gentleman and he will be explains how biological clocks work. greatly missed by all. As we do each year, “When the clock goes awry in mammals, it can lead to many however, we welcomed new students and diseases, ranging from cancer and sleep disorders to heart and faculty members who will help us build lung disease,” said Jonathan Arnold, a professor in the department on existing strengths and further broaden departmental research and training pro- of genetics and leader of the research. “It is very important that grams. Jonathan Arnold we know how the clock works at the molecular level.” This year, the department recruited The research has been published in the online edition of the new faculty in the areas of Molecular Proceedings of the National Academy of Sciences. Epidemiology, Molecular Evolution, and Arnold’s co-authors on the paper were members of a UGA interdisciplinary team, Ecological Genetics. Dr. Mark Jensen, a though several have now moved on to other positions. They include: Heinz-Bernd molecular epidemiologist, holds a joint Schuttler, professor of physics and astronomy at UGA; Yihai Yu, a former graduate appointment in Genetics and in the new see Timekeepers on page 6 UGA College of Public Health. Dr. Jen- sen is applying molecular epidemiological and population genetics approaches to study infectious diseases including HIV NEWS ¦ Undergraduate Program and cholera. Dr. Kelly Dyer, whose re- search specialty is molecular evolution, is pursuing the question of how evolution- R esearch remains a strength of the Genetics department and this certainly includes the contributions of minute presentations by close to half the Genetics Faculty as well as a social hour afterwards. The mixer was aimed ary conflict at many levels shapes the pat- terns of diversity that we observe in natu- ral populations. Dr. Dyer is completing a many Genetics undergraduates. Four at introducing new Genetics majors Royal Society Research Fellowship with laboratory classes are now available to to faculty members as well as to learn Dr. Brian Charlesworth at the University Genetics majors (of which there are 118 about the research that is carried out in of Edinburgh and will join the Genetics declared), and there are also abundant the department. For some students, this faculty in the Fall of 2007. Finally, Dr. opportunities for undergraduate research event helped them decide which lab to do David Moeller, an ecological geneticist, in the labs of Genetics faculty. In independent research in. will join the faculty in the Spring term of Spring 2006, the Genetics Department In other news, current UGA Genetics 2008. Dr. Moeller is studying the influ- Undergraduate Symposium and dinner major Nithya Natrajan was awarded a ence of broad-scale spatial and temporal was held, featuring oral presentations by Mid-term Foundation Fellowship and variation in ecological factors on the evo- eight undergraduates on their independent a Barry M. Goldwater Scholarship for lution of functionally important traits. research. Students presenting were 07-08. Deep Shah, majoring in Genetics His work focuses on studies of plant Cristina Budde, Erica Hall, Allison Koch, and International Affairs, has been species in the genus Clarkia in the Sierra Patrick Pilie, Rebekah Rogers, Jessica named a recipient of a 2007 Harry S. Nevada of California and wild relatives of Shivas, Cale Whitworth, and Brunilis Truman Scholarship, a national award maize endemic to Mexico. Burgos-Rivera. The faculty attending for students who plan careers in public As you will see in these pages, our fac- were in agreement that the quality of the service. Erica Hall was selected to give ulty and students continue to win well-de- presentations was excellent. an oral presentation at the 21st National served recognition for their accomplish- A second event for Genetics majors Conference on Undergrad Research at ments. This year, Dr. Rodney Mauricio was initiated in Fall 2007. The Genetics Dominican University in California in was elected to the UGA Teaching Acade- Student/Faculty Mixer featured ~5 see Undergrad on page 7 see Head’s on page 8
    • vol 3 spring 2007 4 Giles . . . from page 1 T E B operations within cells. While at Yale, Norman convinced Mary A E Case (a research scientist at Oak Ridge M L National Laboratories) to join his research group as a graduate student, and he also I recruited Wyatt Anderson as a young As- E sistant Professor. Mary would become Norman’s life-long collaborator, and as V Professor of Genetics she later followed Back row, L to R: Graeub, Binford, Crain, Paton-Ash E him to the University of Georgia (UGA). Front row, L to R: Scott, Breevoot, Berke At Norman’s urging, Wyatt likewise moved Six UGA students will bike from Oregon to Virginia this summer to raise $60,000 for to UGA where he became the first Head of cancer research. Believe in the Cure was co-founded by Sarah Breevoort (biochemistry the Genetics Department and later Dean and molecular biology) and Nathan Crain (genetics and Spanish). Other members of of the College of Arts and Sciences. Team Believe include Clare Scott (genetics and entomology), John Binford (genetics Norman was elected into the National and psychology), Michael Berke (exercise and sport science), and Megan Cole (UGA Academy of Sciences in 1966, and in alumna and MCG student). Mark Paton-Ash (finance), who is recovering from serious 1972 he was recruited to UGA as a Cal- injuries from an accident while riding his bike in February, will participate in spirit. laway Professor of Genetics, a position that he held until his retirement in 1986. Team Believe is partnered with the American Cancer Society and all proceeds will benefit In Athens, Norman formed an inter-de- the ACS. For more information or to donate visit www.believeinthecure.com partmental program that soon became the Department of Genetics. In addition to maintaining a high-profile research that was before I knew that Norman the Norman’s accomplishments; everyone was program, he recruited and inspired many geneticist was also an avid field naturalist. overwhelmed by the list, and then, upon younger faculty members (including the Indeed, Norman had co-founded the GOS further reflection, even more so by the hu- authors of this obituary). in 1936! Throughout his life, Norman mility of the man himself. Norman’s many contributions to sci- traveled the world with his wife Doris, at- Norman’s intellectual abilities were ence will long be remembered, but those of tending genetic conferences and delivering powerful and his interests broad. He had a us who knew him personally will cherish lectures but also taking many welcome op- boundless appreciation for meaningful hu- even more our memories of his human- portunities to observe the native birds. man accomplishments, and an unbridled ity, warmth, and wit. Over cocktails or at I ( JW) also knew Norman as a wonder- disdain for the converse. Although his dinner parties, Norman could recite, with ful neighbor. Our houses were just a short eyesight and hearing diminished over the equal facility and perfection, the genetic distance apart and Norman and Doris years, his mind remained as engaged and workings of a complex biochemical path- were neighborhood treasures. For depart- sharp as ever. He could listen to a bird’s way, the flute-like song of a wood thrush, mental or other functions, they often host- call—a bird he could no longer see—and or every line from any of dozens of poems. ed parties—legendary events that brought describe from memory its appearance, Norman was a delightful paradox: com- us together as friends as well as colleagues. where it nested, and the many details of fortable and down-to-earth, yet sophisti- Such gatherings on the decks of their mag- its lifestyle. Norman was also socially and cated and complex. His intellectual bril- nificent house, which overlooked a stream, politically engaged. For example, he voted liance was overmatched only by his lack of were almost weekly events. The Giles were in every election even when he needed help pretense. master gardeners and their yard was filled to see and read the ballot. Among his last Norman had more facets that a diamond, with native plants. A few days ago, I no- words on the evening of October 16 were and to best convey this, we ( JCA and JW) ticed with nostalgia that their Cherokee damnations for U.S. activities in the Mid- will each offer a personal anecdote. Shortly Rose was in full bloom, a former signal for dle East and his anger at the horror of the after joining the University of Georgia in the start of spring gatherings. Typical of war in Iraq. 1975, I ( JCA) began to teach Ornithology. Norman’s nature, his non-science neigh- Norman was exceptional in many While thumbing through early issues of bors knew little of his professional accom- ways—as a person, as a colleague, as a The Oriole (the official publication of the plishments, such as the fact that he had mentor, as a neighbor, and as a friend. His Georgia Ornithological Society, or GOS), established a major program of science at legacy will endure for generations of scien- I stumbled upon the name Norman Giles UGA or that he was one of the few mem- tists who will benefit from his pioneering and thought to myself: what a coincidence bers of the National Academy of Sciences work, and for everyone who was privileged that a Georgia birdwatcher would have in the state of Georgia. At a memorial to know this great human being. the same name as the famous molecular gathering after Norman’s death, one such John Avise & Jan Westpheling geneticist in our department. Of course, neighbor shared a newspaper article listing
    • Genetics at georgia 5 Currently an American Cancer Society from her masters’ thesis on genetic testing for Alzheimer’s postdoctoral fellow in Paul Sternberg’s laboratory at the California Institute of A disease in Social Science and Medicine and Patient Educa- tion and Counseling in 2006. Technology, Ryan Baugh (BS ’97) re- Ed Green (BS ‘97) recently gave a Genetics depart- ceived his doctorate from Harvard in 2004. He is investigating developmental l mental seminar on his work on Neandertal DNA. This research was published in Nature in November 2006. physiology in the nematode C. elegans. His paper on the subject was published in u Julie Gunnells, née Letford, (BS ‘01) received her Ph.D. in August 2006 from the University of North Carolina at April 2006 in Current Biology. Chapel Hill and is currently a postdoctoral fellow in the Still at Carolinas Medical Center researching Angelman syndrome and m department of cell biology at Duke University. ß ß ß Prader-Willi syndrome, Lowell Rayburn Combs (PhD ’04) is getting ready to wel- n Shanna Henk, née Carney (PhD ‘96), has left aca- demia and is now at the USDA ARS in Fort Collins, CO come her first batch of transgenic mice to the lab with hopes of gaining insight into i as a safety and occupational health specialist. She is mar- ried to Adam Henk who received his BS from UGA in the pathogensis of AS. zoology. They have two children, Taran (8) and Kasia (2). Kenneth DuBois (BS ’03) is a sec- ond year dental student at LSU in Baton News After retiring from the NFL, Terry Hoage (BS ’85) is now growing yeast cultures again…just really big ones! Rouge. With his wife, Jennifer, he started a winery in Paso Robles, ß ß ß CA and they are now in their 5th vintage. They specialize After trekking in Peru and Bolivia in Rhone varietals and their first production, “The Hedge,” last summer, Joseph Edwards (BS ’04) is paid homage to UGA. back at Emory in his third year of medi- A second-year PhD candidate at Wake Forest University, Katherine House (BS ’04) cal school. He is considering a specialty in is doing organic chemistry research in the lab of Suzanne Tobey. She is married to Chris ophthalmology. Temple and they have a one-year-old daughter, Sarah. Sarah Finch (PhD ’06) is a postdoc- Deborah Ingram (BS ’94) is solo practitioner and owner of Ingram Pediatrics in Fort toral fellow at the Rothberg Institute for Lauderdale where she also holds an ancillary faculty appointment with Nova South- Childhood Diseases, a non-profit dedi- eastern University College of Osteopathic Medicine. She has been a mentor in the Big cated to finding a cure for tuberous scle- Brothers/Big Sisters program since 1999. rosis complex (TSC). Her work on TSC Jonathan Kulbersh (BS ’01) is a second-year otolaryngology resident at the Medical marker discovery may ultimately help University of South Carolina. identify therapeutic agents for specific Working with Howard Ochman in bacterial evolutionary genomics, Renyi Liu (PhD TSC tumor types. ‘05) is a postdoctoral associate at the University of Arizona. Research Renyi conducted Nicole Fitzpatrick (BS ’99) is proj- at UGA with Marjorie Asmussen will be published in Theoretical Population Biology. ect coordinator for the Pediatric Dengue With sanity intact after his first hectic year as assistant professor of biology at the Vaccine Initiative in Mangua, Nicaragua, Mississippi University for Women, Paul Mack (PhD ’01) is busy developing the evolu- working for Sustainable Sciences Insti- tionary biology component of MUWs biology program. tute. Formerly, she served in the Peace ß ß ß Corps in the Dominican Republic after Amy MacRae (PhD ’88) is enjoying her work as a financial services professional at obtaining an MPH from Tulane Univer- Executive Financial Group in St. Louis, MO. Her husband, Gary Brown, is an adjunct sity, and then as a regional epidemiologist professor at Jefferson College teaching biology. for The South Carolina Department of A doctoral student at Emory University in the Population Biology, Ecology, and Evo- Health and Environmental Control. lution program, Andrea McCollum (BS ’99, MS ’02) is working on the population ge- ß ß ß netics of drug resistant malaria. She expects to graduate within a year. Continuing her postdoctoral work in Anna Meyer-Manlapat (BS ’01) completed a PhD in molecular immunology at The Ken Moberg’s lab at Emory, in 2006 Me- Medical College of Georgia in March 2006. She is now engaged in postdoctoral studies lissa Gilbert (BS ’97) was awarded an on the role of mast cells on dendritic cell function in the lab of David Segal at the Experi- NIH NRSA Fellowship to study the role mental Immunology branch of NCI, NIH in Bethesda, MD. of the Drosophila ortholog of mammalian A postdoctoral fellow in Stokes Peebles lab in the Division of Allergy, Pulmonary, Tsg101 in maintaining epithelial cell po- and Critical Care Medicine at Vanderbilt University, Marty Moore (PhD ‘03) is map- larity and growth control. ping the regions of the respiratory syncytial virus (RSV) genome that contribute to air- After completing an MD at UCSF in way dysfunction. He was elected senior co-chair of the Vanderbilt Postdoc Association 2006, Holly Gooding (BS ’00) is now and will again represent postdocs at the National Postdoc Association meeting. working as a resident physician in inter- Lyn Moran, née Stuckey, (BS ’01) is a dancer for “The Wiggles,” an Australian chil- nal medicine at Brigham and Women’s dren’s entertainment group. She married Sam Moran in 2006, and they reside in Sid- Hospital in Boston. She published work ney.
    • vol 3 spring 2007 6 Timekeepers . . . Friends of Genetics from page 3 We proudly recognize alumni and friends student in physics, now working in The UGA team discovered how who have supported our academic programs industry; Wubei Dong, a postdoctoral three genes in Neurospora crassa—bread from June 2006 to date. We are grateful for fellow in Arnold’s lab in genetics; Cara mold—make such a clock tick at the the generosity of all of our donors. If your Altimus, a former UGA undergraduate molecular level. The paper in PNAS name is missing or is listed incorrectly, please and current graduate student at Johns describes how to identify genetic email whites@uga.edu so that we may prop- Hopkins University; Xiaojia Tang, networks and show how the tools of erly acknowledge your generosity. To make a a doctoral student in Schuttler’s lab; systems biology can yield insights into gift to the department, please refer to the gift form on page 7. James Griffith, Arnold’s research what makes the clock tick. coordinator, who is supported by funds “Much of what we know about the Anonymous (2) from the UGA College of Agricultural biological clock comes from the study of Drs. Margaret & Wyatt Anderson and Environmental Sciences; Melissa Neurospora,” said Arnold, “so the insights Dr. Kirby Alton & Mrs. Jan Alton Morello, a former UGA undergraduate, on this clock mechanism are likely to Dr. Jonathan Arnold & now a student at the Medical College of provide insights into clocks of other Mrs. Barbara J. Hartman-Arnold Georgia; and Lisa Dudek, also a former organisms.” Dr. Michael Arnold Dr. Todd E. Arnold undergraduate in physics and now a The discovery also has broad Dr. Mary Bedell graduate student at UCLA. implications for understanding Dr. Michael & Mrs. Alice Bender Because of the importance of biological biochemical signaling and other Drs. Jeffrey L. Bennetzen & Katrien Devos clocks to survival and health, evolution regulatory processes in cells, said Ms. Margaux E. Charbonnet has built them into an astoundingly Arnold. Dr. Lowell Rayburn Combs diverse array of organisms, including Before this research, there has been Drs. Brian Condie & Nancy Manley bacteria and humans. These clocks make little experimental support for any of the Dr. Kelly Dyer it possible for organisms to “tell time,” many existing models of the biological Dr. Shari Freyermuth even in the absence of such stimuli as clock. The UGA team studied actions of Dr. Norman H. Giles temperature changes or daylight. three genes in Neurospora: white-collar-1, Dr. Holly Gooding & white-collar-2 and frequency. The team Mr. Buudoan V. Tran found that the products of these three Dr. Richard E. Green Jr. & Ms. Christine B. Green genes constitute the building blocks of Dr. Robert Glenn Gregerson a biological clock. The discovery crosses Dr. David Hall Alton . . . species boundaries, since human beings Drs. Joseph E. & Robin C. Hightower from page 1 have a gene analogous to white-collar-1. Mr. Bob Inkrot & Ms. Janet Inkrot A number of human diseases are Dr. Bob Ivarie & Ms. Julie Morris associated with genes under control Dr. Shilpa Iyer host-parasite co-evolution and genome of the biological clock. For instance, a Sallie R. Jocoy evolution in protozoan parasites. In both gene called PAI-1 is involved with early- Ms. Meera Kesavan of these projects, he has developed novel morning heart attacks. Another gene Mr. & Mrs. Ram Kesavan computational approaches to address called DBP affects sleep cycles. Both are Dr. Jessica Kissinger questions of biological and evolutionary controlled by clock genes. Drs. Deena & Sidney Kushner significance. Dr. Tong-Ruei Li “One of the most interesting parts of Linder, the 2007-2008 Alton Fellow, Ms. Valerie F. Maples & the research is that the biological clock is a student in the laboratory of Daniel Dr. Richard B. Meagher shows how a complex trait can emerge Dr. Lowell Y. Rayburn Promislow. Linder’s work centers on the from the interaction of even a small interaction between the environment and Dr. Somasekar Seshagiri number of gene regulatory elements,” Ms. Sugithra Somasekar immune function. She is investigating said Arnold. Mr. Bronson K. Strickland & how warmer temperatures assist recovery One interesting aspect of the research is Ms. Kacey M. Jones-Strickland from infection in the model organism the involvement of UGA undergraduates Dr. Thomas C. Talley Drosophila melanogaster. This research Ms. Katherine H. Temple through the Research Experiences for will not only increase our understanding Dr. L. DeEtte Walker Undergraduates program sponsored by of how environmental effects influence the Dr. Joseph H. Williams, Jr. the National Science Foundation. immune system, but also may be relevant Dr. Brenda S. J. Winkel The research published in PNAS to pest control and survival of insect Dr. Charles Yanofsky species as global temperatures increase. also was supported by grants from the National Science Foundation. v
    • Genetics at georgia 7 Undergrad . . . ß ß ß from page 3 In the Molecular Cancer Biology doctoral program at Duke University, Gautham Pandiyan (BS ’04) has been awarded a DOD Pre-doctoral Breast Cancer Research Grant. He also serves on the Board of Directors of the National Association of Gradu- April 2007. ate & Professional Schools and on the Executive Board of the Graduate & Professional Many recent Genetics graduates have School Council at Duke. moved on to professional or graduate Associate Professor Aleksandar Popadić (PhD ‘94) received a 2006 Wayne State schools. Among those we know of University Career Chair Development Award and spent spring of 2007 between Cam- include Hannah Bosdell (M.D. program, bridge University, University of Sussex, and Yale. His wife, Nela, works at the WSU MUSC), Conley Carr (M.D. program, Genomics Center and they have two girls, Lyuba (10) and Sandra (6). Univ. of Alabama), Jonathan Gardner Justin Possner (BS ‘03) is a third-year medical student at Midwestern University, (M.D. program, Ross Univ. School of Arizona College of Osteopathic Medicine, in Glendale. Medicine), Carl Mabry (M.D. program, A research geneticist in the Fruit Laboratory at the Beltsville Agricultural Research LSU), Katie Maher (LSU school of Vet. Center in Maryland, L. Jeannine Rowland (PhD ’87) heads a program to identify mark- Med.), William McMaster Jr. (M.D. ers/genes of horticultural value. For several years, their main focus has been the study of program, MUSC), Oliver Molliere (M.D. genes controlling cold hardiness in the blueberry. program, LSUHSC, Shreveport), Ramya Shenara Austin Sexton, M.D. (BS Biology ‘96) is now Muralimohan (M.D. program, MCG), practicing as a dermatologist in Athens, Georgia. Rebekah Rogers (Ph.D. program in Cindy Buckner Starke (BS ’91) is an internal medicine Organismic and Evolutionary Biology, physician at Montreal Internal Medicine Associates in Tucker, Harvard), David Wiley (Ph.D. program GA specializing in women’s health. She has two children, Jes- in Biology, UNC), Lela Lasiter (M.D. sica Marie (4 ½) and Wyatt Buckner (2 ½). Cindy is active in program, MCG), Adam Perry (M.D. her church and enjoys spending free time with friends, family, program, Emory) J. Grant Zarzour (M.D. camping and hiking. program, Univ. of South Alabama) and Dana and James In February 2005, Dana Hager Underwood (PhD ’02) Burt Wrenn (Pharmacy, UGA). Another and her husband had a baby boy, James. She also enjoys teach- Genetics graduate, George Masoligites, ing biology part-time at Central New Mexico Community College. completed an M.S. in Physics and will Javier Valle (BS ’05) is a first-year medical student at Ponce School of Medicine in join the Biochemistry and Biophysics Puerto Rico. Ph.D. program at the Univ. of California- Compiled by Susan White San Francisco. Mike McEachern I proudly support The Franklin College Department of Genetics You can make a secure online gift by visiting our web site (www. genetics.uga.edu). Please click the “make a gift” link. Alternatively, Make checks payable to the Arch Foundation. return this form with your check to the Department of Genetics. Name(s) _______________________________________ Enclosed is my gift of $______________ , representing a one- (as you wish it to appear on the gift recognition list) time gift, to the following fund (check one): Address _______________________________________ ___ Genetics Department Fund :: This fund supports the ongoing work of the department in teaching and research. _______________________________________ City/State/Zip ___ Genetics Alumni Student Travel Fund :: This fund supports graduate and undergraduate travel to national and international re- Phone/E-mail __________________________________ search conferences. q I would like my gift to be anonymous. ___ Genetics Alumni Graduate Support Fund :: This fund sup- ports graduate fellowships. Please mail your gift to the Department of Genetics, Fred C. Davi- son Life Sciences Complex, University of Georgia, Athens, Georgia Your gift is tax deductible. AFASGEN207 30602-7223 If you would like to make a pledge gift, please contact Linda Bachman at lbachman@franklin.uga.edu or (706) 542-4658.
    • Department of Genetics Nonprofit Org. Fred C. Davison Life Sciences Complex U.S. Postage PAID University of Georgia Permit No. 165 Athens, Georgia 30602-7223 Athens, GA LAURELS Professor pens new book on evolution as a “web of life” ñ Professor Michael Arnold has been elected as a Research Fel- Oxford University low of Merton College, University of Oxford. Press has published a new book by Profes- ñ Erica Hall has been chosen to give an oral presentation at the sor Michael Arnold, 21st National Conference on Undergraduate Research at Do- Evolution through minican University of California in April 2007. She also was Genetic Exchange, in selected as runner up for the UGA Libraries Undergraduate which he describes Research Award. evolution as a web that crosses and re- ñ The UGA Research Foundation has named Professor Robert crosses through genetic exchange. In the Ivarie as this year’s recipient of the Inventor’s Award. book, Arnold argues that the predomi- nant evolutionary metaphor, a tree-like ñ Chih-Horng Kuo, a doctoral student, has been awarded the pattern of diversification to represent James L. Carmon Scholarship for innovative use of computers. evolutionary change in all life forms, is ñ Associate Professor Nancy Manley has been selected as a inadequate to represent evolutionary member of the NIH Skeletal Biology Development and Dis- change in all life forms . ease Study Section. ñ Associate Professor Rodney Mauricio has been elected to the Head’s . . . University of Georgia Teaching Academy for his achievements from page 3 in teaching and learning. my for his accomplishments in teaching and ñ Professor Richard Meagher has been appointed a Distinguished learning and Dr. Richard Meagher was ap- Research Professor by the UGA Research Foundation. pointed to a UGA Distinguished Research ñ Doctoral candidate Nandita Mullapudi has received a 2007 Professorship. Student awards included the Outstanding Teaching Assistant Award. Harry S. Truman and Barry M. Goldwater awards, both prestigious national awards, ñ Nithya Natrajan has been awarded a Mid-Term Foundation Fel- the Carmon Scholarship, the ARCS Foun- lowship and a 2007-2008 Barry M. Goldwater Scholarship. dation Scholarship, and a UGA Outstand- ñ Doctoral student Rebecca Tomlinson has been named an ARCS ing Teaching Award. Finally, your gifts have greatly strength- Foundation Scholar for her studies in the biogenesis and intra- ened our research and teaching programs. cellular trafficking of teleomerase. These gifts contribute in very real ways to ñ Deep Shah has been named a recipient of a 2007 Harry S. Tru- the many accomplishments of our students man Scholarship. and faculty, and we are deeply grateful for your continued support. Bob Ivarie