Genetics and Addiction

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  • Drug addiction is a chronic disease characterized by changes in the brain which result in a compulsive desire to use a drug.
  • Drug addiction is a chronic disease characterized by changes in the brain which result in a compulsive desire to use a drug.
  • The reward pathway is responsible for driving our feelings of motivation, reward and behavior.
  • Drug addiction is a chronic disease characterized by changes in the brain which result in a compulsive desire to use a drug.
  • Genetics and Addiction

    1. 1. University of Utah Department of Human Genetics The New Science of Addiction Louisa A. Stark, Ph.D. Director
    2. 2. http://learn.genetics. utah . edu /units/addiction/index. cfm
    3. 3. Addiction is similar to other diseases http://www.drugabuse.gov/scienceofaddiction/addiction.html
    4. 4. <ul><li>Natural reward pathways exist in the brain </li></ul><ul><li>Drugs of abuse alter the brain’s natural reward pathways </li></ul><ul><li>Genetics is a factor in addiction </li></ul><ul><li>Timing and circumstances influence addiction </li></ul><ul><li>Addiction is a treatable disease </li></ul>Key points
    5. 5. http://learn.genetics. utah . edu /units/addiction/reward/
    6. 6. http://learn.genetics. utah . edu /units/addiction/drugs/
    7. 7. http://learn.genetics. utah . edu /units/addiction/genetics/
    8. 8. http://learn.genetics. utah . edu /units/addiction/factors/
    9. 9. http://www.drugabuse.gov/scienceofaddiction/strategy.html
    10. 10. http://www.drugabuse.gov/scienceofaddiction/addiction.html
    11. 11. Treatment and recovery http://www.drugabuse.gov/scienceofaddiction/treatment.html
    12. 12. Components of effective treatment <ul><li>Treatment medications </li></ul><ul><ul><li>Treat withdrawal symptoms </li></ul></ul><ul><ul><li>Help the brain adapt to the absence of the drug </li></ul></ul><ul><ul><li>Prevent relapse by interfering with triggers </li></ul></ul>http://learn.genetics. utah . edu /units/addiction/issues/treatments. cfm
    13. 13. Components of effective treatment <ul><li>Behavioral therapies </li></ul><ul><ul><li>Cognitive behavioral therapy </li></ul></ul><ul><ul><li>Motivational incentives </li></ul></ul><ul><ul><li>Motivational interviewing </li></ul></ul><ul><ul><li>Group therapy </li></ul></ul>http://www.drugabuse.gov/scienceofaddiction/treatment.html
    14. 14. http://www.drugabuse.gov/scienceofaddiction/treatment.html
    15. 15. <ul><li>Natural reward pathways exist in the brain </li></ul><ul><li>Drugs of abuse alter the brain’s natural reward pathways </li></ul><ul><li>Genetics is a factor in addiction </li></ul><ul><li>Timing and circumstances influence addiction </li></ul><ul><li>Addiction is a treatable disease </li></ul>Key points
    16. 16. To learn more http://learn.genetics. utah . edu /units/addiction/index. cfm

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