Albert de la Chapelle
Curriculum Vitae
                                     CURRICULUM VITAE
                             ...
Albert de la Chapelle
Curriculum Vitae

Fellowships, Medical and Academic Appointments

1955           Studied cardiology ...
Albert de la Chapelle
Curriculum Vitae
Other Major Appointments, Finland Continued
 7.      Department of Gene Technology,...
Albert de la Chapelle
Curriculum Vitae
  Member, European Molecular Biology Organization (EMBO), 1989
Awards and Honors, I...
Albert de la Chapelle
Curriculum Vitae
    Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, collabor...
Albert de la Chapelle
Curriculum Vitae
    Title: Method for diagnosis of ovarian dysgenesis. Approved 12/98

Co-Inventor ...
Albert de la Chapelle
Curriculum Vitae
Annals of Clinical Research                          Journal of the American Medica...
Albert de la Chapelle
Curriculum Vitae


Acted As Official Opponent at Doctoral Dissertations
University of Oulu, Finland:...
Albert de la Chapelle
Curriculum Vitae
1997           Dr. Pia Höglund: "Molecular Genetics of Congenital Chloride Diarrhea...
Albert de la Chapelle
Curriculum Vitae
2001.2003      Claudia Baldus, M.D., "The molecular basis of acute leukemia"
2004-2...
Albert de la Chapelle
Curriculum Vitae
Finska Läkaresällskapet, (Finland) 1953-
Finnish Medical Association, 1957-
Human G...
Albert de la Chapelle
Curriculum Vitae
 18.    "Star Lecturer", Short Course in Medical and Experimental Mammalian Genetic...
Albert de la Chapelle
Curriculum Vitae
Major Invited Talks

  1. Department of Medical Genetics, University of Uppsala, Sw...
Albert de la Chapelle
Curriculum Vitae
Major Invited Talks Continued
 21.    Institute of Anthropology and Human Genetics,...
Albert de la Chapelle
Curriculum Vitae

Major Invited Talks Continued
  42. Nordic Research Course on Environmental Geneti...
Albert de la Chapelle
Curriculum Vitae

Major Invited Talks Continued
 63. Department of Medicine, Flinders Medical Center...
Albert de la Chapelle
Curriculum Vitae

 Major Invited Talks Continued
  82. Eighth International Congress of Histochemist...
Albert de la Chapelle
Curriculum Vitae
  99.   National Cancer Institute, Frederick Cancer Center, Frederick, Maryland, US...
Albert de la Chapelle
Curriculum Vitae



Major Invited Talks Continued
 117. 13th Congress of the European Society of Med...
Albert de la Chapelle
Curriculum Vitae
 134. Nordic Cancer Union, Symposium on Genetics of Cancer, Åbo, Finland, September...
Albert de la Chapelle
Curriculum Vitae
        Lecture: "Genetics of Colon Cancer."
156. United European Gastroenterology ...
Albert de la Chapelle
Curriculum Vitae
 173. Fifth International Congress on Hormones and Cancer, Quebec, Canada, Septembe...
Albert de la Chapelle
Curriculum Vitae
       Lecture: “HNPCC Prevention: Molecular Testing of Known Family Members and Mo...
Albert de la Chapelle
Curriculum Vitae
       1999
       Lecture: “Genetic Predisposition to Colon Cancer.”
 209. The Bur...
Albert de la Chapelle
Curriculum Vitae
       Lecture: “Molecular Screening for Mismatch Repair Related Cancer.”
 226.The ...
Albert de la Chapelle
Curriculum Vitae
 241.Fox Chase Cancer Institute: Cancer Genetics 2005, Bridging Science to Practice...
Albert de la Chapelle
Curriculum Vitae




                        27
Albert de la Chapelle
Curriculum Vitae
 Invited Local Talks, Lectures and Seminars
  Events Before 1971 Not Listed

    1....
Albert de la Chapelle
Curriculum Vitae

Invited Local Talks, Lectures and Seminars Continued
   22. Grand Rounds, Central ...
Albert de la Chapelle
Curriculum Vitae
Invited Local Talks, Lectures and Seminars Continued
   41. Nordic Ecumenic Union, ...
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  1. 1. Albert de la Chapelle Curriculum Vitae CURRICULUM VITAE Albert de la Chapelle, M.D., Ph.D. Name Albert de la Chapelle Date and Place of Birth February 11, 1933, Helsinki, Finland Nationality Finnish Permanent Resident, USA Business Address Human Cancer Genetics Program Comprehensive Cancer Center The Ohio State University 646 Medical Research Facility th 420 West 12 Avenue Columbus, OH 43210 614/688-4781- Phone 614/688-4772 - Fax e-mail: delachapelle-1@medctr.osu.edu Current Major Positions 2004 - Distinguished University Professor, The Ohio State University (OSU) 2004 - Cancer Scholar, OSU 1997 - Leonard and Charlotte Immke Professor of Cancer Genetics, Department of Molecular Virology, Immunology and Medical Genetics, OSU 1997- Co-director, Molecular Biology and Cancer Genetics Program, Comprehensive Cancer Center and Arthur G. James Hospital and Richard J. Solove Research Institute, OSU 1999 - Professor, Division of Human Genetics, Department of Internal Medicine, College of Medicine and Public Health, OSU 2000 - Professor, Department of Molecular Genetics, College of Biological Sciences, OSU Education 1941-1950 Nya Svenska Läroverket: (High School) Helsingfors, Finland, graduated 1950 1950-1957 University of Helsinki, Finland. Faculty of Medicine. MD 1957 1958-1962 University of Helsinki, Finland. Faculty of Medicine. Ph.D. Human Genetics 1962 Certifications 1957 - Licensed to practice medicine, Finland 1965 - Board certified in Internal Medicine, Finland 1986 - Board certified in Clinical Genetics, Finland Previous Major Positions 1969 -2003 Head, The Folkhälsan Institute of Genetics, Helsinki, Finland 1974 -1997 Professor and Chairman, Department of Medical Genetics, University of Helsinki, Finland 1977-1997 Physician-in-Chief, Clinical Genetics, Helsinki University Central Hospital, Finland 1990.1997 Head, Hereditary Disorders Research Unit and Center of Excellence, University of Helsinki, Finland 1997 - 2004 Head, Division of Human Cancer Genetics, Department of Molecular Virology, Immunology Medical Genetics, College of Medicine and Public Health, OSU 1997 - 2004 Director, Human Cancer Genetics Program, Comprehensive Cancer Center and Arthur G. James Hospital and Richard J. Solove Research Institute, OSU 1999 – 2002 Director, Division of Human Genetics, Department of Internal Medicine, OSU
  2. 2. Albert de la Chapelle Curriculum Vitae Fellowships, Medical and Academic Appointments 1955 Studied cardiology at Hôpital Boucicaut (Professor J. Lenègre), Paris, as recipient of French Government Stipend (3 months) 1958 Ship Doctor, The Johnson Line (South America) (3 months) 1958-1962 Resident, Internal Medicine (17 months) Diagnostic Radiology (9 months), Gynecology (2 months), Helsinki Teaching Hospitals, Finland 1956-1957 General Practitioner (3 months) 1959-1962 Junior Investigator, The Minerva Institute for Medical Research, Helsinki 1962-1990 Senior Investigator, The Minerva Institute for Medical Research, Helsinki 1959.1962 Resident, The Samfundet Folkhälsan Clinic for Teenagers, (22 months, part time), Helsinki, Finland 1963-1965 Resident, Internal Medicine, University of Helsinki, Finland 1965-1974 Senior Career Investigator, the Finnish National Research Council for Medical Sciences (The Academy of Finland) 1965-1974 Docent of Medical Genetics, University of Helsinki, Finland 1966.1968 National Institutes of Health, International Postdoctoral Research Fellow at the Department of Medicine, laboratory of Dr. Paul A. Marks, Columbia University College of Physicians and Surgeons, New York (two years) 1973 Acting Professor of Medical Genetics, University of Helsinki, Finland (six months) 1974 Visiting Scientist, MRC Blood Group Unit (Drs. R.R. Race and R. Sanger) and MRC Biochemical Genetics Unit (Dr. E.B. Robson), London (3 months) 1981.1982 Visiting Scientist, Institut National de la Santé et de la Recherche Médicale, INSERM, Institut de Pathologie Moléculaire (Dr. J.C. Kaplan), Université Paris V (one year) (Recipient of Senior Scientist Award of the Academy of Finland) 1985-1995 Research Professor, the Academy of Finland 1986-1989 Visiting Professor, Department of Medicine and Institute of Human Genetics, University of Minnesota, Minneapolis, MN, USA 1989-1997 Visiting Professor, Roswell Park Cancer Institute, Buffalo, NY, USA 1995-1997 Research Professor, the University of Helsinki Other Major Appointments, Finland 1. Medix Incorporated, vice chairman of the board and consultant 1965-1999 2. Central Medical Board of Finland, permanent consultant for genetics 1970-1996 3. Central Medical Board of Finland, member (genetics) 1976-1988 4. Väestöliitto, The Finnish Population and Family Welfare Federation, Department of Genetics, member 1975-1990 5. The Sigrid Jusélius Foundation, Medical Board, secretary 1984-1988, member 1984-1997, vice chairman 1995-1997) 6. The Finska Läkaresällskapet (Finnish Medical Society), member of board 1984-1986, president 1985, vice president 1986, member of grants committee 1981-1991, (chairman 1986-1991), honorary member 1996 2
  3. 3. Albert de la Chapelle Curriculum Vitae Other Major Appointments, Finland Continued 7. Department of Gene Technology, University of Helsinki, member of the board 1983-1986 8. Ministry of Education, member of working group to develop medical teaching in Swedish, 1986 9. Academy of Finland, member of planning committee for a Finnish genome initiative, 1993-1994 10. Svenska Kulturfonden (Swedish Cultural Foundation of Finland), consultant 1995-1998 11. Samfundet Folkhälsan, Committee for the Genetics Clinic, chairman 1995- 12. Finnish National Board of Medicolegal Affairs, Permanent Member, 1996-2000 Military Activities 1954-1955 Served in Finnish Army as conscript (11 months). Promoted to Ensign 1955 (Anti-aircraft corps) 1955 Promoted to Lieutenant (Medical corps) Awards and Honors, Finland The J.W. Runeberg Prize for Research, The Finska Läkaresällskapet (The Finnish Medical Society), 1962 Member, Finska Vetenskapssocieteten (Finland's Senior Academy of Sciences and Letters), 1975 Corresponding member, Finnish Association of Dentists, 1978 Working member, Samfundet Folkhälsan, 1979 The E.J. Nyström Prize for Research, The Finska Vetenskapssocieteten (Finland's Senior Academy of Sciences and Letters), 1981 Commander of the Order of the Finnish Lion, 1984 150 Year Anniversary Prize for Research, The Finska Läkaresällskapet (The Finnish Medical Society), 1985 The Matti Äyräpää Prize for Medicine, Medical Society Duodecim, Finland, 1990 Commander of the Order of the White Rose of Finland, 1992 Honorary doctorate, University of Oulu, 1994 Corresponding member, The Dental Society, 1995 Honorary member, The Finska Läkaresällskapet (The Finnish Medical Society), 1996 Esko Nikkilä Lecturer, 1996 Fellow (“one of twelve") of the Academy of Finland, 1997 Honorary member, Finland’s Senior Academy of Sciences and Letters, 1998 Honorary member, The Finnish Society of Medical Genetics, 1998 The Ossian Schauman Medal, Samfundat Folkhälsan, 2003 The Niilo Voipio Award, the Finnish Cancer Organizations, 2003 Awards and Honors, International Member, European Society for Clinical Investigation, 1970 Jubilee Medal 1958 in Bronze with Diploma, Svenska Läkaresällskapet (The Swedish Society of Medicine), 1988 The Anders Jahre Prize for Medicine, University of Oslo, 1989 175 year Anniversary Commemorative Medal, Oslo University School of Medicine, 1989 3
  4. 4. Albert de la Chapelle Curriculum Vitae Member, European Molecular Biology Organization (EMBO), 1989 Awards and Honors, International Continued Member, Royal Swedish Academy of Sciences, 1991 International Phoenix - Anni Verdi Award for Genetic Research (Italy) 1994 Honorary doctorate, University of Uppsala, 1995 Hamilton Fairley Award, European Society for Medical Oncology, 1996 Tim de Dombal Award and Lectureship, World Congress of Gastroenterology, 1998 European Society of Human Genetics Annual Award for Scientific Excellence (the Mauro Baschirotto Award), 2002 German Society of Human Genetics, GfH Medal of Honor, 2006 Awards and Honors, USA Member, Foreign associate, National Academy of Sciences, USA 1997 Simon M. Shubitz Award (University of Chicago), 1998 Wick R. Williams Memorial Award (Fox Chase Cancer Center), 1998 William Allan Award (American Society of Human Genetics), 2002 Fellow, American Association for the Advancement of Science, 2002 Highly Cited; Molecular Biology and Genetics, www.isihighlycited.com, 2003 Member, Association of American Physicians, 2005 Activities in International and National Bodies; Advisory Boards; Review Panels European Society of Human Genetics, Board member, 1966-1995; Chairman of Aims and Statutes Committee, 1990-1991; President, 1993-1994 European Environmental Mutagen Society, councillor, 1974-1976 The Finnish Society of Medical Genetics, Founding member and first president, 1977-1980 The International Congress of Human Genetics, member of permanent committee, 1981-1986 The International Workshops on Chromosomes in Leukemia, member of advisory board, 1984-1990 The International Human Gene Mapping Workshops, executive committee, Chairman, 1983-1985; Member, 1985-1991 European School of Haematology, member of scientific committee, 1985- International Conferences on Prenatal Diagnosis & Therapy, member of advisory board 1986-1990 The Seventh International Congress of Human Genetics, Berlin, member of organizing committee, 1986 The Ninth International Chromosome Conference, Marseille, member of scientific committee, 1986 Howard Hughes Medical Institute, member of ad hoc committee on Human Genome Mapping, 1986 Association des Cytogénéticiens de Langue Francaise, member, 1988- The Eighth International Congress of Human Genetics, Washington, DC 1991, member of executive program committee, 1988-1991 The International Olympic Committee, member of Working Group on Gender Verification, 1988 The Tenth International Chromosome Conference, Uppsala 1989, member of organizing committee, 1989 4
  5. 5. Albert de la Chapelle Curriculum Vitae Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, collaborating investigator, 1990- Activities in International and National Bodies; Advisory Boards; Review Panels Continued Department of Medical Genetics, University of Uppsala, Sweden, member of Scientific Advisory Board, 1990- Steering Committee of the Nordic Human Genome Project, Member, 1990-1997 The Human Genome Organization (HUGO), Member 1989- Member, Gene Mapping Committee, 1991-1992 European Union, Member of Concerted Action on Genetic Studies in Cancer Families,1990-1997; Member of Concerted Action on Genetic Analysis of Epilepsy, 1992-1997; Member of Research Network on the Biological History of European Populations, 1994-1997; Scientific Advisory Group on Human Genome Research, Member, 1994; BIOMED 2, Grants Review Committee for Human Genome Research, Chairman (Rapporteur), 1995 Genome Interactive Databases, member of Editorial Committee, 1994- European Commission Working Group on Cancer Research, Member, 1996 General Motors Mott Prize Selection Committee, 1997 The Wellcome Trust, member of the Genetics Advisory Group, 1997- Reviewer of grants for various agencies and foundations in Finland, USA, Iceland, italy, France, Denmark, Canada, the Netherlands, Sweden, UK, Germany, New Zealand, 1997- Faculty member, First Baltic Postgraduate Course in Medical Genetics, Vilnius, Lithuania, May 1997 Faculty member, Course on “Chromosome and Gene Alterations in Cancer” University of Helsinki, Nov 30-Dec 4, 1998 Reviewer, National Cancer Institute Site Visit, MIT, Cancer Center, Cambridge, MA, 1999 Primary reviewer for the appointment to a chair in Clinical Genetics, University of Uppsala, 1999-2000 Primary reviewer of nominations to the Louis Jeantet Prize in Medicine, University of Geneva, Switzerland. Presentation of winner, Jean-Louis Mandel at Prize Ceremony, 1999 International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer, member of Council, 2000 – International Cytogenetics and Genome Society, Founding member, 2002 Member, External Advisory Board, Cleveland G-I SPORE, 2003 Reviewer, Centres of Excellence Programme, Denmark, 2003 Member, Scientific Advisory Board, Genome Atlantic, Canada, 2004 Member, External Advisory Board, Case Western Reserve University Cancer Genetics Program, Comprehensive Cancer Center, 2006 Member, International Multidisciplinary Community Genetics Network, 2007 Co-Inventor on the following patents: Title: Anhidrotic ectodermal dysplasia gene and method of detecting same. Approved 9/96 Title: Means for detecting familial colon cancer (FCC). Approved 2/96 Title: Diagnostic method employing MSH2 nucleic acids. Approved 12/97 Title: Human MSH2 protein. Approved 1/97 Title: Molecular cloning of the anhidrotic ectodermal dysplasia gene. Approved 12/97 Title: Diagnostic method employing MSH2 protein. Approved 11/98 5
  6. 6. Albert de la Chapelle Curriculum Vitae Title: Method for diagnosis of ovarian dysgenesis. Approved 12/98 Co-Inventor on the following patents continued: Title: Tumor classification as indication of hereditary non-polyposis colorectal carcinoma. Approved 2/99 Title: BAALC protein isoforms, potential new markers for human acute leukemia and hematopoietic and neuropoietic stem cells. Submitted 8/20/01 Title: Cystatin B mutants. Approved 8/02 Title: Identification and molecular characterization of FXGAG, fragile X site associated gene: a novel gene associated with short stature. Submitted 6/02 Title: Procedure for the detection of PMS2 specific mutations, Submitted 7/06 Editorships of Books Chromosomes Today, Volume 6, (editors A de la Chapelle and M Sorsa) Elsewier/North Holland, Amsterdam, pp 1-415, 1977 Human Gene Mapping 8, Karger, Basel, pp 1-823, 1985 Editorships of Journals European Journal of Human Genetics, Associate Editor, 1991- Human Mutation, Communicating Editor, 1991- Blood Cells, Molecules & Diseases, Corresponding Editor, 1997- Memberships of Editorial Boards Acta Endocrinologica (Advisory Panel), 1965-1983 Annales de Génétique, 1975- Cancer Genetics and Cytogenetics, 1980-1987 Clinical Genetics, 2000- Community Genetics, 1997-2008 Current Cancer Therapy Reviews, 2004- Cytogenetics and Cell Genetics, 1977-1983 EMBO Journal, 1997-2002 EMBO Reports, 2000-2002 Encyclopedia of the Human Genome, 1999 European Journal of Haematology, 1987-1994 Excerpta Medica, Human Genetics, 1975- Familial Cancer, 1999- Finska Läkaresällskapets Handlingar, 1971-1980 Genes, Chromosomes and Cancer, 1989- Genomics, 1987- Haematologica, 1999- Human Heredity, 1984-2005 International Journal of Cancer, 1999- Journal of Clinical Oncology, 2006- Public Health Genomics Journal 2008- Scandinavian Journal of Haematology, 1976-1986 Reviewer for Journals in Addition to the Above Acta Paediatrica Scandinavica Human Molecular Genetics American Journal of Human Genetics International Journal of Andrology American Journal of Medical Genetics International Journal of Cancer 6
  7. 7. Albert de la Chapelle Curriculum Vitae Annals of Clinical Research Journal of the American Medical Association Annals of Human Genetics Journal of Clinical Investigation Biochimie Journal of Clinical Oncology Reviewer for Journals in Addition to the Above Continued Biomedicine Journal of Internal Medicine Biotechniques Journal of Medical Genetics Blood Journal of the National Cancer Institute British Journal of Cancer Lancet Cancer Research Leukemia Research Carcinogenesis Molecular Medicine Today Cell Mutation Research Chromosoma Nature Clinical Cancer Research Nature Genetics Clinical Genetics Nature Medicine Disease Markers New England Journal of Medicine Duodecim Oncogene European Journal of Cancer Scandinavian Journal of Rheumatology European Journal of Pediatrics Science Experimental Cell Research Pediatric Research Gene Reviews PLoS Genetics Human Genetics Proceedings of the National Academy of Sciences, USA Declared Eligible by the Appropriate Panels for 1968 Full Professorship in Medical Genetics, Faculty of Medicine, University of Oslo, Norway 1970 Associate Professorship in Genetics, Faculty of Sciences, University of Helsinki, Finland 1971 Full Professorship in Internal Medicine, University of Helsinki, Finland 1971 Full Professorship, in Medical Genetics, University of Århus, Denmark 1973 Associate Professorship in Chromosome Research, Faculty of Sciences, University of Lund, Sweden Acted As Official Opponent at Doctoral Dissertations University of Helsinki, Finland: 1965 Dr. Pertti Aula: "Virus-Associated Chromosome Breakage" 1971 Dr. Jaakko Leisti: " Structural Variation in Human Mitotic Chromosomes" 1972 Dr. Svante Stenman: "Chromosome Pulverization Induced by Paramyxo-viruses" University of Lund, Sweden: 1970 Dr. Leif Håkansson: "On the Distribution of Proteins and Nucleic Acids along Human Metaphase Chromosomes" 1979 Dr. Alf Hansson: "Association Between Human Acrocentric Chromosomes" The Karolinska Institute, Stockholm, Sweden: 1989 Dr. Catharina Larsson: "Recessive Mutations in Tumorigenesis of Human Breast Carcinoma and Multiple Endocrine Neoplasia Type 1" 7
  8. 8. Albert de la Chapelle Curriculum Vitae Acted As Official Opponent at Doctoral Dissertations University of Oulu, Finland: 1990 Dr. Sirkka Liisa Hostikka: "Human Type IV Collagen. Characterization of the a-2(IV) Chain and the 3' End of Its Gene, and Identification of a Novel a-5(IV) Chain with Mutations in Alport Syndrome" Supervisor of Doctoral Candidates University of Helsinki, Finland: 1970 Dr. Johan Edgren: "Effect of Cysteine on Chromosome Aberrations Induced by Radiation of Human Lymphocytes in vitro" 1971 Dr. Johan Wennström: "Effect of Ionizing Radiation on the Chromosomes in Meiotic and Mitotic Cells" 1974 Dr. Ritva-Kajsa Selander (Åbo Akademi): "Kromosomala makromolekylers effekt på vissa akridinderivats absorption och fluorescens" 1975 Dr. Jim Schröder: "Passage of Blood Cells Between Foetus and Mother" 1979 Dr. Olli Turunen: "Stimulation of Human Fetal, Cord Blood and Maternal Lymphocytes by Mitogenic Agents" 1980 Dr. Georg H. Borgström: "Clinical Implications of Chromosome Aberrations in Hematologic Neoplasia" 1981 Dr. Riitta Herva (University of Oulu): "Q and C Band Chromosomal Heteromorphisms in a Northern Finnish Population" 1984 Dr. Kalle Simola: "X-linked Mental Retardation with the Marker X Chromosome - A Clinical and Cytogenetic Study" 1988 Dr. Mauri Keinänen: "Lineage-Specific Chromosome Analysis of Hematopoietic Cells" 1989 Dr. Juha Kere: "Molecular Abnormalities of Chromosome 7 in Myeloid Disorders" (with honors) 1989 Dr. Anna-Elina Lehesjoki: "Hemophilia A: Molecular Studies in Finnish Families" 1990 Dr. Mikael Lindlöf: "Duchenne and Becker Muscular Dystrophy: DNA studies in Finnish families" 1991 Dr. Tiina Alitalo: "Gene Mapping of Juvenile Retinoschisis and Åland Island Eye Disease on the Human X Chromosome" and Molecular Study" 1991 Dr. Eeva-Marja Sankila: "Choroideremia: a Genetic and Molecular Study" 1991 Dr. Päivi Peltomäki: "Molecular Genetic Alterations in Human Testicular Cancer" 1992 Dr. Johanna Hästbacka: "In Search of the Diastrophic Dysplasia Gene. Genetic Mapping of the Disease Locus" (with honors) 1994 Dr. Lauri Aaltonen: "Molecular Genetic Background of Hereditary Nonpolyposis Colorectal Cancer" (with honors) 1994 Dr. Tuija Sulisalo: "Genetic Mapping of the Gene for Cartilage-Hair Hypoplasia" 1995 Dr. Pia Salo: "Molecular and Clinical Genetics of the Human Y Chromosome. Mapping of Three Genes" 1995 Dr. Esa Tahvanainen: "Mapping Genes of the Finnish Disease Heritage: Cohen syndrome, Northern epilepsy, and Cornea plana congenita" 1995 Dr. Minna Nyström-Lahti: "Genetic Predisposition to Hereditary Non-Polyposis Colorectal Cancer" 1996 Dr. Kristiina Aittomäki: "Genetics of Hereditary Ovarian Dysgenesis" (with honors) 8
  9. 9. Albert de la Chapelle Curriculum Vitae 1997 Dr. Pia Höglund: "Molecular Genetics of Congenital Chloride Diarrhea" 1998 Dr. Akseli Hemminki: “Inherited Predisposition to Gastrointestinal Cancer: the Molecular Backgrounds of Peutz-Jeghers Syndrome and Hereditary Non-polyposis Colorectal Cancer” (with honors) 1998 Dr. Kimmo Virtaneva: “The Molecular Genetics of Progressive Myoclonus Epilepsy: Positional Cloning of the Cystatin B Gene and Characterization of a Novel Minisatellite Expansion Mutation” 1999 Dr. Susanna Ranta: “Positional Cloning of the Progressive Epilepsy with Mental Retardation Gene (CLN8)” (with honors) Supervisor of Doctoral Candidates University of Helsinki, Finland Continued: 2000 Dr. Stina Roth: "Molecular Genetic Background of Juvenile Polyposis" 2000 Dr. Maria Aminoff-Backlund: “Molecular Genetics of Selective Intestinal Malabsorption of Vitamin B12 The Gräsback-Imerslund Disease (Megaloblastic Anemia 1)” 2000 Dr. Kristiina Avela: “Positional Cloning of the Mulibrey Nanism Gene (MUL)” 2002 Dr. Anu-Liisa Moisio : “Predisposing and Modifying Genes in Hereditary Colorectal Cancer Syndromes ” 2002 Dr. Tarja Joensuu: “ Positional Cloning of the Usher Syndrome Type 3 Gene (USH3)” 2004 Dr. Juha Kolehmainen: ”Molecular Genetics of Cohen Syndrome” 2004 Dr. Reijo Salovaara: ”Molecular Pathology of Hereditary Colon Cancer” Supervisor of Doctoral Candidates The Ohio State University 1997-2000 Dr. Robert Chadwick, “Discovery and Genetic Analysis of Genes Involved in Hereditary and Sporadic Colorectal Cancer” 1998-2002 Dr. Ying Huang, “The Genetics of Papillary Thyroid Cancer” 1998-2006 Dr. Heejei Yoon, “Molecular Genetics of Thyroid Cancer” Supervisor of Postdoctoral Scientists 1975-1976 Janusz Limon, Ph.D., “Molecular basis of chromosome banding” 1977-1978 Bogdan Kaluzewski, M.D., “Human cytogenetics” 1990.1996 Anna-Elina Lehesjoki, M.D., Ph.D, “The genetics of epilepsy” 1991-1994 Päivi Peltomäki, M.D., Ph.D., “The genetics of colorectal cancer” 1992-1996 Eeva-Marja Sankila, M.D., Ph.D., “The genetics of eye disorders” 1994-1996 Lauri Aaltonen, M.D., Ph.D., “The genetics of colorectal cancer” 1994-2000 Maaret Ridanpää, Ph.D., “The molecular basis of cartilage hair hypoplasia” 1995-1996 Federico Canzian, Ph.D., “Microsatellite instability in human pathology” 1995-1997 Jose Luis Dieguez Lucena, M.D.,“The molecular genetics of the follicle-stimulating hormone receptor” 1995.1997 Ralf Krahe, Ph.D., “Genes predisposing to multifatorially determined human disease” 1996-1997 Antonio Percesepe, M.D., Ph.D, “Predisposition to colon cancer” 1996-2000 Katarina Pelin, Ph.D., “The genetics of muscle disorders” 1997-1999 Bru Cormand, Ph.D., “The molecular genetics of muscle disorders” 1998-2000 Natalia Pellegata, Ph.D., “The genetics of nasopharyngeal carcinoma” 1998-2005 Stephan Tanner, Ph.D., “The molecular basis of acute myeloid leukemia” 1999-2003 Hidewaki Nakagawa, M.D., Ph.D., “Loss of imprinting in colon cancer” 9
  10. 10. Albert de la Chapelle Curriculum Vitae 2001.2003 Claudia Baldus, M.D., "The molecular basis of acute leukemia" 2004-2007 Mark Clendenning, Ph.D., “The molecular basis of hereditary cancer” 2004-2007 Kaisa-Mari Sotamaa, M.D., “Modifier genes in colorectal cancer predisposition” 2005-2007 Christian Langer, M.D., “BAALC in leukemia” 2003-present Huiling He, Ph.D., (Research Scientist): “The molecular basis of papillary thyroid cancer” 2004-present Krystian Jazdzewski, Ph.D., ”Genes predisposing to thyroid cancer” 2006-present Laura Valle, Ph.D., “The genetics of colorectal cancer” Supervisor of Postdoctoral Scientists 2008-present Jerneja Tomsic, Ph.D. “Genes in colorectal cancer predisposition” Supervisor of Clinical Fellows, The Ohio State University 1999.2000 Darius Desai, M.D., “A recurrent de novo mutation in MSH2” 2000.2001 Emmanuel Zervos, M.D., “Genetic predisposition to pancreatic cancer” 2003.2005 Anjali Satoskar, M.D., “BAALC in neuropoiesis and hematopoiesis” Supervisor of Undergraduate Students, with Honors, The Ohio State University 2003-2007 Kyle Walsh, BS “New haplotype and genealogical data give important implications for the origins and prevalence of the American founder mutatin of MSH2”. With distinction. Organizer of International Conferences and Symposia President, Sixth International Chromosome Conference, Helsinki, Finland, 1977 Co-organizer, First International Workshop on Chromosomes in Leukemia, Helsinki, Finland, 1977 Head of Organizing Committee, International Symposium on Clinical Genetics, Helsinki, Finland, 1977 President, Third Nordic Conference on Medical Genetics, Helsinki, Finland, 1984 Organizer, Eighth Human Gene Mapping Workshop, Helsinki, Finland, 1985 Co-organizer, Nobel Symposium on the Etiology of Human Disease at the DNA level, Björkborn, Sweden 1990 Organizer and Chairman, Research Conference on Inherited Disorders and Their Genes in Different European Populations, sponsored by the European Science Foundation, Eurovillage Obernai, France, 1993 Co-organizer, Research Conference on Inherited Disorders and Their Genes in Different European Populations, sponsored by the European Science Foundation, San Feliu de Guixols, Spain, 1995 Conference Committee, 14th EORTC-NCI-AACR Symposium on “Molecular Targets and Cancer Therapeutics”, Frankfurt, Germany, 2002 Memberships in Societies/Organizations American Association for the Advancement of Science, 1984- American Association for Cancer Research, 1997- American Society Clinical Oncology, 2002- American Society of Human Genetics, (corresponding member) 1966- European Society of Human Genetics, 1966- Finnish Association of Hematology, 1965- Finnish Association of Internal Medicine, 1965- Finnish Association of Medical Genetics, 1976- 10
  11. 11. Albert de la Chapelle Curriculum Vitae Finska Läkaresällskapet, (Finland) 1953- Finnish Medical Association, 1957- Human Genome Organization (HUGO), 1989- Societas Biochemica, Biophysica et Microbiologica Fenniae, (Finland) 1974- Societas Genetica Fennica, (Finland) 1964- Association of American Physicians, 2005- Teaching Responsibilities University of Helsinki 1. Internal Medicine, 1963-1965 2. Medical Genetics, 1964-1974 3. Organized postdoctoral course in Human Genetics, 1968 4. As Professor and Chairman of Medical Genetics, responsible for pre- and postdoctoral teaching and training, 1974- 5. As Professor and Chairman of Medical Genetics responsible for teaching, training and licensing in Clinical Genetics, 1982- 6. Head of Graduate School in Medical Genetics, 1994-1997 7. Co-organized a postgraduate course on “Physical Mapping of Genes”, 1996 8. Co-organized a postgraduate course on “Linkage Disequilibrium in Human Gene Mapping”, 1997 9. Faculty member Course on “Chromosome and Gene Alterations in Cancer” University of Helsinki, Nov, 30-Dec. 4, 1998 (one lecture) Teaching Responsibilities Elsewhere 1. Nordic Course "Genetics in the Medical Curriculum", Århus, Denmark, 1970 2. WHO Training Course on the Diagnostic Techniques for Chromosome Aberrations, Stockholm, Sweden, 13.8-4.9., 1971 3. Population Biology, Faculty of Medicine, University of Turku, Finland, 1972 4. Scandinavian Summer School of Male Reproductive Biology, University of Turku, Finland, June 5-17, 1972 and June, 1983 5. Genetics, Faculty of Medicine, University of Turku, Finland, 1975 6. Organized and led Postgraduate Course in Clinical Genetics, University of Helsinki, Finland, 1976 7. Organized and led a Session on Cytogenetic Diagnostics in Acute Leukemia at Symposium of the Nordic Cancer Union, Turku, Finland, 1976 8. Organized and led Postgraduate Course on Genetics of Common Disorders, Helsinki, Finland, 1979 9. EMBO Course on the Chromosomal Localization of Genes, Paris, France, 1982 and 1983 10. American Society of Clinical Oncology, Educational Workshop, Toronto, Ontario, Canada, May, 1984 11. Advanced Course in Human Genetics, University of Minnesota, Minneapolis, MN, USA, 1986, 1987, 1988 12. Faculty member, European School of Medical Genetics, Sestri Levante (Genova), Italy, April 6-12, 1988 (several lectures) 13. Co-organized Course on Cytogenetics and Molecular Genetics in Haematological Malignancy, European School of Haematology, Chateau de Maffliers, France, April 18-22, 1988 14. Co-organized International Symposium "Exploring the Human Genome", Helsinki, Finland, November 21, 1988 15. Faculty member, European School of Medical Genetics, Sestri Levante (Genova) Italy, April 1-7, 1990 (several lectures) 16. Faculty member, European School of Medical Genetics, Sestri Levante (Genova) Italy, April 5-8, 1992 (two lectures) 17. Faculty member, Course on "Mechanisms of Sex Determination and Intersexuality. Basic and Clinical Aspects" in Buenos Aires, Argentina, October 6, 1992 (2 lectures) 11
  12. 12. Albert de la Chapelle Curriculum Vitae 18. "Star Lecturer", Short Course in Medical and Experimental Mammalian Genetics, Bar Harbor, ME, USA, July 1995 (two lectures) 19. Faculty member, First Baltic Postgraduate Course in Medical Genetics, Vilnius, Lithuania, May 1997, (two lectures) 20. Examiner, Habilitation, Université Louis Pasteur, Strasbourg for Dr. Stanislas du Manoir, “Analyse des aberrations chromosmiques and de leurs conséquences transcriptionnelles dans les tumeurs malignes par cytogénétique moléculaire et puces d’ADN”, May 28, 2002 Teaching Responsibilities Ohio State University 1997 - present 1. Faculty Member, Dept. of Molecular Virology, Immunology and Medical Genetics course 734, Human Cancer Genetics, 2000 - 2. Faculty Member, Integrated Biomedical Science Graduate Program, Molecular Genetics 880.06, Module 2, Genes and Genome Organization, 2000 - Major Courses Attended 1. Course in Human Cytogenetics. MRC Clinical Effects of Radiation Research Group, Edinburgh, Scotland, 1960 2. Gordon Research Conference on Cell Structure and Metabolism, Meriden, New Hampshire, USA 1967 3. Short Course in Genetics (organized by The Johns Hopkins University and The Jackson Laboratory), Bar Harbor, Maine, USA 1968 4. Workshop on Morphogenetic Tissue Interactions, Helsinki, Finland, 1969 5. Gordon Research Conference on Developmental Biology, Andover, New Hampshire, USA 1970 6. EMBO Summer School on The Separation of Macromolecules and Particles, Uppsala, Sweden, 1971 7. Postgraduate Course on Gene Technology, The Pasteur Institute, Paris, France, March-April 1982 Discontinued in 1982 12
  13. 13. Albert de la Chapelle Curriculum Vitae Major Invited Talks 1. Department of Medical Genetics, University of Uppsala, Sweden, 1960 Seminar: "Satellite Association of Human Acrocentric Chromosomes." (in Swedish) 2. Conference of the Nordic Society of Clinical Pathologists, Savonlinna, Finland, 1961 Lecture: "Study on Human Chromosomes." (in Swedish) 3. Nordic Conference on Clinical Cytogenetics, Uppsala, Sweden, 1961 Lecture: "Cytogenetics of Turner's Syndrome." (in Swedish) 4. Conference of the Nordic Society of Internists, Lund, Sweden, 1962 Lecture: "Chromosomes in Inborn Errors of Metabolism." (in Swedish) 5. Ninth Congress of the European Society of Haematology, Lisbon, Portugal, 1963 Lecture: "Factors Stimulating Cell Division in Cultures Leucocytes. Chemical, Serological and Immunological Studies on Mitogens." 6. Third Conference of the Nordic Society of Geneticists, Helsinki, Finland, 1964 Lecture: "Isochromosomes for the Long Arm of the Human X Chromosome." (in Swedish) 7. Meeting of the Nordic Fertility Club, Lund, Sweden, 1966 Lecture: "Males with Female Chromosomes." (in Swedish) 8. Symposium on the Labelling of Mammalian Chromosomes, Manchester, England, 1966 Lecture: "Isochromosome-X in Man." 9. Department of Pathology, Dartmouth College School of Medicine, Hanover, New Hampshire, USA, 1967 Lecture: "Males with Female Chromosomes." 10. Department of Pathology, University of Colorado, Denver, Colorado, USA, 1967 Lecture: "Males with XX Sex Chromosomes." 11. Department of Biology, City of Hope Medical Center, Duarte, California, USA, 1967 Lecture: "Males with Female Chromosomes." 12. Department of Biology, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA, 1968 Lecture: "Differentiation of Erythroid Cells." 13. Laboratorio di Radiobiologia, CNEN, Rome, Italy, 1970 Lecture: "Erythroid Cell Specialization: DNA-RNA Hybridization Experiments." 14. Symposium of the European Society of Human Genetics, "Determination and Differentiation of Sex, Ghent, Belgium, 1970 Lecture: "The Development of Testes in the Apparent Absence of Y Chromosome Material." 15. Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York, USA, 1970 Lecture: "Transcription in Differentiating Fetal Erythroid Cells." 16. Department of Terrestrial Magnetism, The Carnegie Institute of Washington, Washington, DC, USA, 1970 Lecture: "The Control of Differentiation in Erythroid Cells." 17. Institute of Human Genetics, University of Hamburg, Germany, 1971 Lecture: "Glutathione Reductase and other Enzyme Activities in Haematological Disorders Associated with C Trisomy." 18. Department of Pediatrics, University of Hamburg, Germany, 1971 Lecture: "The Control of Differentiation in Erythroid Cells." 19. Max-Planck Institute for Experimental Medicine, Göttingen, Germany, 1971 Lecture: "Erythroid Cell Specialization: DNA-RNA Hybridization Experiments." 20. International Symposium on The Synthesis, Structure and Function of Hemoglobin. Bad Nauheim, Germany, 1971 Lecture: "Molecular Control of Differentiation: DNA, RNA and Haemoglobin Synthesis in the Erythroid Cells of Fetal Mice." 13
  14. 14. Albert de la Chapelle Curriculum Vitae Major Invited Talks Continued 21. Institute of Anthropology and Human Genetics, University of Heidelberg, Heidelberg, Germany, 1971 Lecture: "The Etiology of Human XX Males." 22. Nobel Symposium No 23. Chromosome Identification -- Techniques and Applications in Biology and Medicine, Stockholm, Sweden, 1972 Lecture: "Cytogenetical and Clinical Aspects of Trisomy-8 in the Bone Marrow." 23. Nobel Symposium No. 23. Chromosome Identification -- Techniques and Applications in Biology and Medicine, Stockholm, Sweden, 1972 Lecture: "Sequential Denaturation and Reassociation of Chromosomal DNA in situ." 24. Norsk Hydro's Institute for Cancer Research, Oslo, Norway, December 18, 1972 Lecture: "What is the Basis of Chromosome Banding." (in Swedish) 25. Institute of Medical Genetics, University of Oslo, Norway, December 20, 1972 Lecture: "Immunological Interaction Between Mother and Child." (in Swedish) 26. Meeting of the Nordic Society of Haematology, Helsinki, Finland, June 1, 1973 Lecture: "The Significance of Chromosome Investigations in the Diagnosis of Malignant Hematologic Diseases." (in Swedish) 27. Institute of Genetics, University of Glasgow, Scotland, April 29, 1974 Lecture: "Pericentric Inversions in Human Chromosomes 9 and 10." 28. Department of Genetics, University of Aberdeen, Scotland, May 3, 1974 Lecture: "Human Chromosome Polymorphisms." 29. Inaugural Lecture as First Holder of Chair in Medical Genetics, University of Helsinki, Finland, October 23, 1974 Lecture: "Human Genetics Today." (in Finnish) 30. European Congress of Rheumatology, Helsinki, June 3, 1975 Lecture: "Biological Hazards of Radiation." 31. First International Clinical Genetics Seminar, Athens, Greece, May 5, 1976 Lecture: "The Clinical Importance of Human Chromosomal Polymorphisms." 32. Symposium of the European Society of Human Genetics, Athens, Greece, May 8, 1976 Lecture: "Pericentric Inversions in Human C Group Chromosomes." 33. Fifth International Congress of Human Genetics, Mexico City, Mexico, October 11, 1976 Lecture: "The Etiology of XX Males." 34. International Symposium on Clinical Genetics, Helsinki, Finland, January 3, 1977 "Opening Address." 35. International Symposium on Clinical Genetics, Helsinki, Finland, January 4, 1977 Lecture: "Clinical Consequences of Human Pericentric Inversions." 36. Sixth International Chromosome Conference, Helsinki, Finland, August 29, 1977 "Opening Address." 37. Working Conference on Preventable Aspects of Genetic Morbidity, Cairo, Egypt, April 1, 1978 Lecture: "The Occurrence and Prevention of Unbalanced Offspring in Carriers of Reciprocal Translocations." 38. Working Conference on Preventable Aspects of Genetic Morbidity, Cairo, Egypt, April 3, 1978 Lecture: "Nucleated Fetal Cells Circulating in the Maternal Blood. An Alternative Approach to Prenatal Diagnosis." 39. Third European Conference on Prenatal Diagnosis of Genetic Disorders, Munich, Germany, April 13, 1978 Lecture: "Fetal Blood Sampling and Other Alternative Methods." 40. Institute of Endocrinology, The Medical Academy of Lódz, Poland, May 16, 1979 Lecture: "Males with the Karyotype 46,XX." 41. Fourth Polish Cytogenetics Conference, Gdánsk, Poland, May 18, 1979 Lecture: "Human Chromosomal Inversions." 14
  15. 15. Albert de la Chapelle Curriculum Vitae Major Invited Talks Continued 42. Nordic Research Course on Environmental Genetics, Helsinki, Finland, May 23, 1979 Lecture: "Aspects of Mutagenicity and Legislation." 43. Fifth International Workshop on Human Gene Mapping, Edinburgh, Scotland, July 13, 1979 Presentation: "The Map of the Human Y Chromosome." 44. European Society of Human Genetics Symposium on Genetic Aspects of Infertility and Foetal Wastage, Southampton, England, July 20, 1979 Lecture: "The Etiology of XX Males." 45. Meeting of the Nordic Society of Hematology, Ålborg, Denmark, May 20, 1980 Lecture: "Chromosome Aberrations in Acute Lymphatic Leukemia." (in Swedish) 46. Symposium of the European Society of Human Genetics, Dubrovnik, Yugoslavia, October 6, 1980 Lecture: "The Map of the Human X Chromosome." 47. Kroc Foundation Symposium on Sex Determination, Santa Ynez, California, USA, December 11, 1980 Lecture: "The Etiology of Maleness in XX Men." 48. Department of Medicine, University of Chicago, Illinois, December 15, 1980 Lecture: "Human Gene Mapping by Gene Dosage." 49. Division of Medical Oncology, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, December 16, 1980 Lecture: "Human Gene Mapping by Gene Dosage." 50. Symposium of the European Society of Human Genetics, Zürich, Switzerland, March 28, 1981 "Concluding Remarks of the Symposium." 51. Meeting of the Nordic Society of Hematology, Helsinki, Finland, May 15, 1981 Lecture: "Chromosome Aberrations in Acute Lymphatic Leukaemia." (in Swedish) 52. Sixth International Congress of Human Genetics, Jerusalem, Israel, September 15, 1981 Lecture: "Chromosomes in Human Leukemia: Experience of the First Three Workshops." 53. Sixth International Congress of Human Genetics, Jerusalem, Israel, September 15, 1981 Lecture: "Delivery of Genetic Services: Transition from Research to Routine." 54. Serono Symposium on The Genetic Control of Gamete Production and Function. Vienna, Austria, October 12, 1981 Lecture: "The Map of the Human X Chromosome." 55. Institute of Molecular Pathology, University Paris V, France, December 17, 1981 Lecture: "XX Males." (in French) 56. Department of Pediatrics, University of Strasbourg, France, January 26, 1982 Lecture: "XX Males." (in French) 57. Department of Human Genetics, University of Utah, Salt Lake City, Utah, March 8, 1982 Lecture: "The Origin of XX Males." 58. Meeting on Recent Progress in the Genetic Analysis of the X Chromosome, Department of Human Genetics, University of Oxford, England, April 27, 1982 Lecture: "Genetics of Sexual Dysgenesis." 59. Department of Pediatrics, University of Marseille, France, May 6, 1982 Lecture: "The Origin of XX Males." (in French) 60. International Agency for Cancer Research, Lyon, France, May 17, 1982 Lecture: "The Origin of XX Males." (in French) 61. Symposium of the European Society of Human Genetics, Madrid, Spain, October 1, 1982 Lecture: "On the Mechanisms of Origin of XX Males and X Males." 62. Human Genetics Society, Melbourne, Australia, February 22, 1983 Lecture: The Etiology of XX Males." 15
  16. 16. Albert de la Chapelle Curriculum Vitae Major Invited Talks Continued 63. Department of Medicine, Flinders Medical Center, South Australia, February 23, 1983 Lecture: "Chromosomal Mechanisms in Human Leukaemia." 64. Genetics Department, University of Adelaide, Australia, February 24, 1983 Lecture: "The Cytogenetics of Human Lymphoma and the Localization of the Breakpoints of Chromosomes in Burkitt's Lymphoma by in situ Hybridization of Cloned Immunoglobulin Genes." 65. Grand Rounds, Adelaide Children's Hospital, Adelaide, Australia, February 28, 1983 Lecture: "Chromosomal Mechanisms in Leukemia." 66. Department of Medicine, Queen Elizabeth Hospital, Adelaide, Australia, March 2, 1983 Lecture: "Etiology of Maleness in XX Males." 67. South Australia Genetics Group, University of Adelaide, Australia, March 2, 1983 Lecture: "Chromosomal Localization of Single-Copy Genes by in situ Hybridization." 68. Grand Rounds, Queen Elizabeth Hospital, University of Adelaide, Australia, March 3, 1983 Lecture: "Chromosomal Mechanisms in Human Leukemia." 69. Serono Symposium on the Differentiation of Sex, Carmel, California, USA, March 17, 1983 Lecture: "The Etiology of XX Males." 70. Second Nordic Conference of Medical Genetics, Copenhagen, Denmark, May 8, 1983 Lecture: "DNA Technology in the Diagnosis of Hereditary Disorders." (in Swedish) 71. Eighth International Chromosome Conference, Lübeck, Germany, September 22, 1983 Lecture: "Localization of Single-Copy DNA Sequences on Human Chromosomes by in situ Hybridization." 72. Eighteenth Meeting of the German Society of Anthropology and Human Genetics, Münster, Germany, October 7, 1983 Lecture: "The Human X Chromosome." 73. Third Nordic Conference of Medical Genetics, Helsinki, Finland, January 18, 1984 "Opening Address." 74. Department of Haematology, South African Institute for Medical Research, University of the Witwatersrand, Johannesburg, South Africa, March 14, 1984 Lecture: "The Aetiologic Role of Chromosome Abnormalities in Neoplasia." 75. Department of Human Genetics, South African Institute for Medical Research, University of the Witwatersrand, Johannesburg, South Africa, March 14, 1984 Lecture: "The Localization of Single-Copy DNA Sequences on Human Chromosomes by in situ Hybridization." 76. Department of Human Genetics, South African Institute for Medical Research, University of the Witwatersrand, Johannesburg, South Africa, March 15, 1984 Lecture: "The Aetiology of Maleness in XX Males." 77. Department of Human Genetics, Cape Town Medical School, South Africa, March 20, 1984 Lecture: "The Aetiology of Maleness in XX Males." 78. Department of Cytogenetics, Tygerberg Medical School, Stellenbosch University, Tygerberg, South Africa, March 23, 1984 Lecture: "The Etiology of Maleness in XX Males." 79. American Society of Clinical Oncology, Educational Workshop, Toronto, Ontario, Canada, May, 1984 Lecture: "The Etiologic Role of Chromosome Abnormalities in Neoplasia." 80. Center for Cancer Research and The Whitehead Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA, May 10, 1984 Lecture: "The Etiology of Maleness in Human XX Males." 81. Second International Conference on Malignant Lymphoma, Lugano, Switzerland, June 14, 1984 Lecture: "The Chromosomes in Burkitt's Lymphoma."
  17. 17. Albert de la Chapelle Curriculum Vitae Major Invited Talks Continued 82. Eighth International Congress of Histochemistry and Cytochemistry, Helsinki, Finland, August 6, 1984 Lecture: "The Localization of Single-Copy Genes by in situ Hybridization. 83. Conference on Medical Genetics, Past, Present and Future, Oslo, Norway, August 24, 1984 Lecture: "Chromosomal Mechanisms in Human Neoplasia." 84. Conférence INSERM: Structure moléculaire du chromosome Y, relation avec le chromosome X, sa fonction dans la détérmination du sexe chez l'homme normal et en pathologie, Seillac, France, September 27, 1984 Lecture: "Males Without a Y Chromosome: Basic Facts and Recent Evidence." 85. Conférence INSERM: Structure moléculaire du chromosome Y, relation avec le chromosome X, sa fonction dans la détérmination du sexe chez l'homme normal et en pathologie, Seillac, France, September 27, 1984 Lecture: "Concluding Remarks of Conference." 86. Symposium on Myelodysplastic Syndromes, Helsinki, Finland, January 11, 1985 Lecture: "Chromosomal Mechanisms in Neoplasia." 87. Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden, January 14th, 1985 Lecture: "Chromosomal Mechanisms in Neoplasia." 88. Seventh Steno Symposium, Hagedorn Research Laboratory and Steno Memorial Hospital, Gentofte, Denmark, May 13, 1985 Lecture: "Genes Involved in Human Sex Determination and Differentiation." 89. Fourth International Clinical Genetics Seminar "Endocrine Genetics and Genetics of Growth", Athens, Greece, May 21, 1985 90. Third European Conference on Clinical Oncology and Cancer Nursing, Stockholm, Sweden, June 18, 1985 Lecture: "Tumor Cytogenetics." 91. Eleventh World Congress of Gynecology and Obstetrics, Berlin, West Germany, September 18, 1985 Lecture: "DNA Technology in Prenatal Diagnosis." 92. Second International Amateur Athletics Federation Medical Congress, Canberra, Australia, October 2, 1985 Lecture: "The Use and Misuse of Sex Chromatin Screening for "Gender Identification" of Female Athletes." 93. Fourth Nordic Conference on Medical Genetics, Oslo, Norway, January 25, 1986 Lecture: "The Masculinizing Gene." (in Swedish) 94. Institute of Human Genetics, University of Minnesota, Minneapolis, MN, USA, April 10, 1986 Lecture: "The Testis Determining Gene." 95. Cold Spring Harbor Symposium on the Molecular Biology of Homo Sapiens, Cold Spring Harbor, New York, USA, May 29, 1986 Lecture: "Genetic and Molecular Studies on 46,XX and 45,X Males." 96. Marseille Chromosome Conference. Ninth International Chromosome Conference, Marseille, France, June 20, 1986 Lecture: "Males Without a Y Chromosome: Recent Progress." 97. Seventh International Congress of Human Genetics, Berlin, Germany, September 25, 1986. Lecture: "Cytogenetics is as Useful as Ever in the Study of Human Disease." 98. Symposium on Molecular Genetics and Cytogenetics of Human Neoplasia, Berlin, Germany, September 27, 1986 Lecture: "Morphological, Immunological and Molecular Characterization of Bone Marrow Mitoses." 17
  18. 18. Albert de la Chapelle Curriculum Vitae 99. National Cancer Institute, Frederick Cancer Center, Frederick, Maryland, USA, October 7, 1986 Lecture: "Morphological, Immunological and Molecular Characterization of Bone Marrow Mitoses." Major Invited Talks Continued `100. National Institutes of Health, Clinical Genetics Program, Bethesda, Maryland, USA, October 8, 1986 Lecture: "Testis Determination in Man." 101. National Institute of Child Health and Human Development, Center for Population Research. Workshop on Genetic Markers of Sex Differentiation, Bethesda, Maryland, USA, October 10, 1986 Lecture: "The Etiology of Maleness in 45,X, 46,XX and 47,XXX Males." 102. International Symposium "From Man to Gene From Gene to Man", Florence, Italy, November 3, 1986 Lecture: "The Genetics of Sex Determination in Man." 103. The Royal College of Physicians of London, Conference on New Prospects in Genetic Diseases, London, England, December 4, 1986 Lecture: "The Molecular Biology of the Human X Chromosome." 104. British Society for Developmental Biology, Symposium on "The Mammalian Y Chromosome: The Molecular Search for the Sex Determining Gene", Oxford, England, March 25, 1987 Lecture: "Genes on the Human Y Chromosome." 105.European Federation of Child Neurology Societies Meeting, Hyvinkää, Finland, June 15, 1987 Lecture: "The Molecular Biology of Duchenne Muscular Dystrophy." 106. International Conference on the New Genetics and the Human Gene Map, Paris, France, September 12, 1987 Lecture: "Abnormal Sex Determination in Man." 107. 100th Anniversary of the US National Institutes of Health, Celebration at the University of Helsinki, Finland, September, 1987 Lecture: The Molecular Biology of Primary Sex Determination in Man." 108. Department of Human Genetics, University of Manitoba, Winnipeg, Manitoba, Canada, October 28, 1987 Lecture: "The Genetics of Primary Sex Determination in Man." 109. The Faculties of Medicine and of Physical Education and Recreation Studies, University of Winnipeg, Manitoba, Canada, October 29, 1987 Lecture: "Sex Testing in the Olympics." 110.Department of Neurology, Duke University, Durham, N.C., USA, December 9, 1987 Lecture: "The Molecular Genetics of Primary Sex Determination in Man." 111. International Symposium on "Molecular Genetics and Isolated Populations", Helsinki, Finland, January 7, 1988 Lecture: "X- and Y-chromosomal Polymorphisms in the Search for the Testis Determining Factor." 112. National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA, March 15, 1988 Lecture: "Recent Developments in the Molecular Biology of the Y Chromosome." 113. Roswell Park Memorial Institute, Buffalo, New York, USA, March 25, 1988 Lecture: "The Genetics of Primary Sex Determination in Man." 114. Fourth International Symposium of the Belgian Society for Clinical Chemistry, Brugge, Belgium, May 26, 1988 Opening lecture: "General Introduction to Recombinant DNA Technology in Diagnosis." 115.Fifth Nordic Meeting of Medical Genetics, Laugarvatn, Iceland, August 27, 1988 Lecture: "Clinical Genetics in Finland." (in Swedish) 116. International Symposium on the Impact of Medical Genetics on Public Health, Copenhagen, Denmark, October 29, 1988 Lecture: "Impact of Molecular Genetics on the Understanding of Sex Determination and its Abnormalities in Man." 18
  19. 19. Albert de la Chapelle Curriculum Vitae Major Invited Talks Continued 117. 13th Congress of the European Society of Medical Oncology, Lugano, Switzerland, October 30, 1988 Lecture: "Present Impact of Cytogenetics and Molecular Genetics on the Management of Hematologic Malignancies." 118. Department of Medical Genetics, Biomedical Center, University of Uppsala, Sweden, November 28, 1988 Lecture: "The Molecular Genetics of Primary Sex Determination in Man." 119. Department of Clinical Genetics, the Karolinska Hospital, Stockholm, Sweden, November 29, 1988 Lecture: "Primary Sex Determination in Man." (in Swedish) 120. The Swedish Society of Medicine, Stockholm, Sweden, November 30, 1988 Lecture: "The Molecular Basis of Human Sex Determination and Its Abnormalities." (in Swedish) 121. Third International Workshop on Chromosomes in Solid Tumors, Tucson, Arizona, USA, February 28, 1989 Lecture: "Conference Overview." 122. Berzelius Symposium XVIII: Molecular Genetics and Human Disease, Uppsala, Sweden, September 19, 1989 Lecture: "Sex determination." 123. University of Oslo School of Medicine, Oslo, Norway, September 29, 1989 Lecture: "The Molecular Genetics of Sex Determination." (in Swedish) 124. 28th Reunion of the French Society for the Study of Fertility, Paris, France, October 19, 1989 Lecture: "Human Sex Reversal." (in French) 125.International Symposium on the Molecular Genetics of Sex Determination, New Orleans, LA, USA, April 30, 1990 Lecture: "XX Males and XX true Hermaphrodites." 125. VII World Congress on Human Reproduction, Helsinki, Finland, June 28, 1990 Lecture: "The Genetics of Testis Determination." 127.Royal College of Pathologists of Australasia and the Haematology Society of Australia, Christchurch, New Zealand, October 3, 1990 Lecture: "Clinical Utility of Molecular Diagnostics and Cytogenetics in Leukemia." 128.Third Hematology Update Symposium of the Puerto Rican Society of Hematology, San Juan, Puerto Rico, October 12-14, 1990 Lecture: "Introduction to Cytogenetics and Molecular Diagnostics for the Hematologist." Lecture: "The Use of Molecular Diagnostics in Leukemia/Lymphoma." 129.RP Foundation Fighting Blindness Workshop on Progress in Genetic Studies on Retinal Degeneration, Cincinnati, Ohio, USA, October 16, 1990 Lecture: "Localization of Åland Island Eye Disease Locus by Linkage Analysis." 130. International Athletic Foundation Workshop on the Approved Methods of Gender Verification, Monte Carlo, Monaco, November 10, 1990 Lecture: "Why Sex Chromatin Screening should be Abandoned as a Method for Gender Verification." 131. Center for Genetics in Medicine, Washington University School of Medicine, St. Louis, Missouri, USA, April 26, 1991 Lecture: "Population variation in human genetic disease: the example of Finland." 132. Colorectal Cancer Workshop, National Cancer Institute, Baltimore Maryland, USA, May 1, 1991 Lecture: "Linkage Studies in Hereditary Colorectal Cancer." 133. First Nordic Genome Workshop, Visby, Sweden, May 16, 1991 Lecture: "Population Genetics of Inherited Disorders in Isolated Populations." 19
  20. 20. Albert de la Chapelle Curriculum Vitae 134. Nordic Cancer Union, Symposium on Genetics of Cancer, Åbo, Finland, September 20, 1991 Lecture: "Familial Cancer Syndromes." Major Invited Talks Continued 135.Howard Hughes Medical Institute, Workshop on the Causes and Consequences of Chromosome Rearrangements in Human Leukemia and Lymphoma, Bethesda, Maryland, USA, October 6, 1991 Lecture: "Chromosome 7 in Myeloid Leukemia." 136.Istituto Giannina Gaslini, Genova, Italy, January 10, 1992 Lecture: "Sex Determination and Sex Chromosome Abnormalities." 137. European Society of Human Genetics, 24th Annual Meeting, Elsinore, Denmark, May 27-31, 1992 Lecture: " Inherited Diseases in Genetic Isolates." 138. 1st Nordic HUGO Workshop on Genetic Mapping, Aarhus, Denmark, September 21-23, 1992 Lecture: "Linkage Disequilibrium Mapping in Isolated Populations". 139. Endocrinological Research Center, Buenos Aires, Argentina, October 7, 1992 Lecture: "Males Without a Y Chromosme." 140. National Cujo University, Mendoza, Argentina, October 9, 1992 Lecture: "Males Without a Y Chromosome." 141. Whitehead Institute, Cambridge, MA, March 25 1993 Lecture: "The Study of Hereditary Disorders in Isolated Populations." 142.XXVI Nordic Meeting of Gastroenterology, Tampere, Finland, May 27, 1993 Lecture: Lecture: "Genetics of Hereditary Non-polyposis Colorectal Carcinoma." 143.Japanese Digestive Disease Week, Kobe, Japan, September 22, 1993 Lecture: "The Hereditary Component of Colorectal Cancer." 144.Sixth Tokyo Symposium for Colorectal Surgery, Tokyo, September 25, 1993 Lecture: "The Hereditary Component of Colorectal Cancer." 145. European Concerted Action on Genetic Analysis of Epilepsy, Montpellier, France, November 5, 1993 Lecture: "A New Autosomal Recessive Childhood Epilepsy." 146. European Research Conference on Inherited Disorders and Their Genes in Different European Populations, Obernai, France, November 27, 1993 Lecture: "Linkage Disequilibrium in Mapping and Cloning of Recessively Inherited Disease Genes." 147. Institute of Medical Genetics, Oslo, Norway, December 13, 1993 Lecture: "The Genetics of Colorectal Cancer." (in Swedish) 148. Roswell Park Cancer Institute, Buffalo, NY, January 7, 1994 Medical Grand Rounds Lecture: "Hereditary Colorectal Cancer." 149. Cancer Progress 1994 Conference, New York, NY, February 28, 1994 Lecture: "Hereditary Colon Cancer”. March of Dimes 25th Clinical Genetics Conference, Orlando, FL, March 15, 1994 Lecture: “The Genetics of Colorectal Cancer.” 150. American College of Medical Genetics, First Conference, Orlando, FL, March 16, 1994 Lecture: “Heredity in Nonpolyposis Colorectal and Related Human Cancers.” 151. Fourth European Workshop on Cytogenetics and Molecular Genetics of Human Solid Tumors, Noordwijkerhout, April 23, 1994 Lecture: “The Genetics of Colorectal Cancer.” 153. National Cancer Institute and National Center for Human Genome Research Workshop on Hereditary Breast, Ovarian and Colon Cancer, Washington DC, April 27, 1994 Lecture: “Molecular Epidemiology of Colon Cancer.” 152. Cancer and Leukemia Group B, 1994 Spring meeting, Washington DC, April 30, 1994 Lecture: “Hereditary Colon Cancer.” 155. International Genetic Epidemiology Society, Paris, June 1, 1994 20
  21. 21. Albert de la Chapelle Curriculum Vitae Lecture: "Genetics of Colon Cancer." 156. United European Gastroenterology Week, Oslo, Norway, June 26, 1994 Lecture: "Recent Advances in GI Cancer Genetics." Major Invited Talks Continued 157. Fourth Workshop of the Nordic Genome Initiative, Helsinki, Finland, September 4, 1994 Lecture: "The Molecular Epidemiology of Hereditary Colon Cancer." 158. International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer, Milan, Italy, September 11, 1994 Lecture: "Future Perspectives." 159. Societas Biochemica Biophysica et Microbiologica Fenniae, Biosciences Conference, Helsinki, Finland, September 16, 1994 Lecture: "Predictive Testing in Hereditary Colon Cancer." 160. Italian Federation of Human Genetics (FISME), Ninth Annual Conference, Spoleto, Italy, September 28, 1994 Lecture: "Hereditary Colon Cancer." 161. American Society of Human Genetics, 44th Annual Meeting, Montreal, Canada, October 19, 1994 Lecture: "Dominant Mutator Model: Hereditary Non-polyposis Colon Cancer: Clinical and Phenotypic Effects." 162. Genes and Diseases, San Raffaelle International Biomedical Science Park, Telethon Italy, Milano, Italy, November 11, 1994 Lecture: "Linkage Disequilibrium in Isolated Populations as a Tool in the Positional Cloning of Disease Genes: the Example of Finland." 163. Sloan-Kettering Memorial Cancer Center, New York, NY, November 16, 1994 Lecture: "The Role of Mismatch Repair Genes in Hereditary Colon Cancer." 164. First Annual Symposium on Human Molecular Genetics, University of Antwerp, Antwerp, Belgium, November 26, 1994 Lecture: "Hereditary Colon Cancer." 165. EUROFAP, EC Concerted Action: Genetic Studies in Cancer Families, Genetics of FAP and HNPCC, Budapest, Hungary, December 3, 1994 Lecture: " Spectrum of HNPCC Mutations." 166. IKA (the Comprehensive Cancer Centre Amsterdam) 15th Anniversary International Congress on Colorectal Cancer: from Gene to Cure, University of Amsterdam, Amsterdam, February 9, 1995 Lecture: "Epidemiology of Inherited Susceptibility to Colorectal Cancer." 167. IKA (the Comprehensive Cancer Centre Amsterdam) 15th Anniversary International Congress on Colorectal Cancer: from Gene to Cure, University of Amsterdam, Amsterdam, February 9, 1995 Lecture: "DNA Mismatch Repair Genes in the Causation of Colorectal Cancer." 168. 400-Year Anniversary Jubilee Symposium on Cancer - from Molecular Mechanisms to Clinical Therapy, University of Uppsala, Uppsala, Sweden, March 23, 1995 Lecture: "Genetic Mechanisms in Hereditary Colon Cancer." 169. Workshop on Genetic Screening for Colorectal Cancer, National Cancer Institute, Bethesda, MD, April 10, 1995 Lecture: "A Population-Based Study to Determine the Incidence of HNPCC." 170. European Society of Human Genetics, 27th Annual Meeting, Berlin, Germany, May 25, 1995 Lecture: "Hereditary Colorectal Cancer." 171. IIIrd KTL-Symposium on Molecular Mechanisms of Disease, Espoo, Finland, May 29, 1995 Lecture: "Inherited Predisposition to Colon Cancer and Associated Cancers" 172. International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer, Helsinki, Finland, September 15, 1995 Lecture: "Molecular Genetics in Epidemiological Evaluation of HNPCC." 21
  22. 22. Albert de la Chapelle Curriculum Vitae 173. Fifth International Congress on Hormones and Cancer, Quebec, Canada, September 19, 1995: Lecture: "Genetic Instability and Cancer." Major Invited Talks Continued 174. Fifth International Congress on Hormones and Cancer, Quebec, Canada, September 19, 1995: Lecture: "Genetic Instability and Cancer." 175. American Association for Cancer Research, Special Conference entitled "Cancer: The Interface Between Basic and Applied Research", Baltimore, Nov 6, 1995 Lecture: "Hereditary Non-Polyposis Colorectal Cancer: Translating Molecular Advances into Clinical Practice." 176. Euroconference, Human Genome Variation in Europe: DNA markers, Barcelona, Nov 9, 1995 Lecture: "DNA Mismatch Repair Gene Mutations: a "New" Class of Human Disease Susceptibility." 177. Symposium on "Genetic Aspects of Mental Retardation", University of Uppsala, Department of Clinical Genetics, December 8, 1995 Lecture: "The Nordic Disease Heritage." (in Swedish) 178. Creighton University, Omaha, Nebraska, March 20, 1996 Lecture: "Is Hereditary Colorectal Cancer an Example of a Cancer that is Preventable Thanks to Genetic Testing?" 179. St. Jude Children’s Research Hospital, Memphis, TN, April 11, 1996 Lecture: "Is Hereditary Nonpolyposis Colorectal Cancer an Example of a Cancer that is Truly Preventable Thanks to Genetic Testing?" 180. The Baptist Memorial Health Care Foundation Forum on Cancer Research, Memphis, TN, April 12, 1996 Lecture: "Is Hereditary Nonpolyposis Colorectal Cancer an Example of a Cancer that is Truly Preventable Thanks to Genetic Testing?" 181. National Cancer Institute Second International Conference "From Gene Cloning to Populations", Frederick, MD, June 27, 1996 Lecture: "Population-Based Studies of Colon Cancer Susceptibility Genes." 182. University of Texas MD Anderson Cancer Center, Houston, TX, July 1, 1996 Lecture: "Population-Based Studies of Colon Cancer Susceptibility Genes in Finland." 183. Whitehead Symposium on Cancer, Cambridge, MA, October 21, 1996 Chairman of Session and lecture: "Origins of Cancer." 184. Third Annual Genetic Linkage Symposium, San Francisco, CA, October 22, 1996 Lecture: "Replication Error and Loss of Heterozygosity in Tumors." 185. American Society of Human Genetics, Annual Meeting, San Francisco, CA, October 23, 1996 Workshop Lecture: "The Finnish Population Structure as a Model of Founder Population." 186. European Society of Medical Oncology, 21st Congress, Vienna, November 4, 1996 Hamilton Fairley Lecture: "Is Hereditary Non-Polyposis Colorectal Cancer an Example of a Common Cancer that is Truly Preventable Thanks to Genetic Testing?" 187. Karolinska Institute, Microbiology and Tumor Biology Center, Stockholm, January 17, 1997 Lecture: "Hereditary Predisposition to Colon Cancer." 188. University of Utah, Eccles Institute of Human Genetics, Salt Lake City, UT, February 4, 1997 Lecture: “Hereditary Colon Cancer.” 189. American Association of Cancer Research, Annual Meeting, San Diego, CA, April 15, 1997 Organizer of Symposium and Lecture: “Identification and Management of High-Risk Individuals: Colon Cancer.” 189. UICC Symposium on Familial Cancer and Prevention, Kobe, May 14, 1997 22
  23. 23. Albert de la Chapelle Curriculum Vitae Lecture: “HNPCC Prevention: Molecular Testing of Known Family Members and Molecular Screening in sporadic Colorectal Cancer Patients." 190. Cleveland Clinic Foundation Retreat, Salt Fork State Park, Ohio, September 8, 1997 Lecture “Genes Predisposing to Colorectal Cancer.” Major Invited Talks Continued 191. European Conference of Clinical Oncology, Annual Meeting, Hamburg, Germany, September 17, 1997 Chairman of Session and Lecture: “Prevention and Cure of Colorectal Cancer.” 192. Tenth Meeting of the International Institute of Genetics and Biophysics, CNR: Genome-Based Analysis of Gene Regulation and Its Evolution, Capri Italy, October 12, 1997 Lecture: Evolution and Function of a Disease-Causing Minisatellite Expansion Mutation.” 193. American Society of Human Genetics, 47th Annual Meeting, Baltimore, MD, October 29, 1997 Lecture: “The Population History of Epilepsy Mutations.” 194. Case Western Reserve University, Cleveland, Ohio, April 27, 1998 Lecture: “Genetic Predisposition to Colon Cancer.” 195. University of Chicago, Chicago, Illinois, May 7, 1998 Simon M. Shubitz Cancer Lecture: “Genetic Predisposition to Colon Cancer.” 196. European Society of Human Genetics Annual Meeting, Lisbon, Portugal, May 13, 1998 Lecture: “High-and Low-Penetrance Genes in Cancer Predispositions.” 197.International Association of Cancer Registries, 32nd Annual Conference, Atlanta, Georgia, August 17, 1998 Lecture: “Colon Cancer Genetics.” 198. Tim de Dombal Lecture, World Congress of Gastroenterology, Vienna, Austria, September 10, 1998 Lecture: “Molecular Screening Strategies to Identify Individuals at High Risk for Colorectal and Endometrial Cancer.” 199. XIX Congress of Polish Oncological Society, Gdansk, Poland, September 11, 1998 Lecture: “Genes Predisposing to Colorectal Cancer.” 200. Conference: The Future is Now: Genetics in Cancer Prevention and Diagnosis, Dayton, Ohio, September 25, 1998 Lecture: “From Laboratory to Clinic: The Impact of the Discovery of Genes for Hereditary Colon Cancer on Current Patient Management.” 201.Wick R. Williams Memorial Lecture, Fox Chase Cancer Center, Philadelphia, PA, September 28, 1998 Lecture: “Genetic Predisposition to Colon Cancer.” 202. Dana-Farber Cancer Institute Seminars in Oncology and the Harvard Longwood Seminar in the Genetics of Cancer and Aging, Boston, MA, December 15, 1998 The David G. Nathan Lecture, “Hereditary Predisposition to Colon Cancer.” 203. Genetics and Molecular Biology…From Discovery to Practice, Honolulu, Hawaii, February 23, 1999 Lecture: “Hereditary Cancer Susceptibility Syndromes.” 204. Medical Scientist Training Program, and Department of Genetics, Baylor College of Medicine, Houston, Texas, March 30, 1999 Lecture: “Genetic Predisposition to Colorectal Cancer.” 205. Finnish Academy of Science, Helsinki, Finland, April 29, 1999 Lecture: “Genetic Predisposition to Cancer.” (in Swedish) 206. American Society of Clinical Oncology, Thirty-Fifth Annual Meeting, Atlanta, Georgia, May 15-18, 1999 Educational Lectures: “Molecular Genetic Diagnosis for Hereditary Cancer.” 207. ECCO 10, The European Cancer Conference, Vienna, Austria, September 15, 1999 Lecture: “Genes Predisposing to Colon Cancer.” 208. Department of Molecular Genetics, Biochemistry & Microbiology, University of Cincinnati, October 5, 23
  24. 24. Albert de la Chapelle Curriculum Vitae 1999 Lecture: “Genetic Predisposition to Colon Cancer.” 209. The Burnham Institute, San Diego, California, Distinguished Seminar Series, November 9, 1999 Lecture: “Genes Predisposing to Colorectal Cancer.” Major Invited Talks Continued 210. Department of Medical and Molecular Genetics, Indiana University School of Medicine, November 18, 1999 Lecture: "Hereditary Colon Cancer." 211. Gordon Research Conference on “Genes and Cancer: Pathways, Mutations and Genomics.”, Newport, Rhode Island, August 6, 2000 Keynote Lecture: “Molecular Genetics of Colon Cancer in the Clinical Context.” 212. The 12th International Collaborative Group for Hereditary Non-polyposis Colorectal Cancer Meeting, Tiberias, Israel, September 20, 2000. Lecture: ”Population-wide Molecular Screening for HNPCC-Should it be Done.” 213. The Genetic Challenge Symposium, Department of Genetics, Lund University, Lund, Sweden, October 6, 2000 Keynote Lecture: “Cancer is a Genetic Disease.” 214. Rudbeck Symposium: Cancer—from Molecular Mechanisms to Clinical Therapy, Uppsala, Sweden, October 10, 2000 Lecture: “Genetic Predisposition to Colon Cancer.” 215. Gastrointestinal Cancer Symposium, University of California, San Francisco, November 14, 2000 Lecture: “Has Gene Discovery Benefitted the Colorectal Cancer Patient?” 216. Keystone Symposium: The Molecular Medicine of Colorectal Cancer, Taos, New Mexico, February 3, 2001 Lecture: "Genetic Predisposition to Colorectal Cancer." 217. University of Wisconsin Genetics Colloquium on the Genetic Analysis of Human Biology, Madison, Wisconsin, February 14, 2001 Lecture: "Hereditary Colon Cancer: Molecular Diagnosis, Population-wide Screening and Prevention." 218. American Association for Cancer Research, Conference on Genetic Modifiers of Cancer Susceptibility: Lessons from Human Population Studies and Mouse Models, Lake Tahoe, Nevada, February 26, 2001 Lecture: "Methylation and Imprinting in Colon Cancer." 219. Université Libre de Bruxelles, Fondation Erasme, Brussels, Belgium, April 20, 2001 Lecture: “Can Genetic Testing be Used in the Prevention of Cancer?" 220. Tenth International Congress of Human Genetics, Vienna Austria, May 17, 2001 Lecture: "Has Gene Detection Benefitted the Cancer Patient?” 221. Yonsei University, Seoul, Korea, September 10, 2001 Lecture: "Hereditary Nonpolyposis Colorectal Cancer: Population-based Molecular Screening and its Implications." 222. American Association for Cancer Research International Conference Seoul, Korea, September 11, 2001 Lecture: "Population-based Molecular Screening for HNPCC and its Implications." 223. American Society of Human Genetics Annual Meeting, San Diego, California, October 14, 2001 Lecture: "Hereditary Nonpolyposis Colorectal Cancer: Natural History, Mutation Detection and Molecular Screening." 224. National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, November 13, 2001 Grand Rounds Lecture: "Population-based Molecular Screening for Hereditary Nonpolyposis Colorectal Cancer and its Implications." 225.American Association for Cancer Research Conference on Colon Cancer: Genetics to Prevention, Philadelphia, PA, March 8, 2002 24
  25. 25. Albert de la Chapelle Curriculum Vitae Lecture: “Molecular Screening for Mismatch Repair Related Cancer.” 226.The Finnish Association for Medical Genetics, 25th Anniversary Seminar, Helsinki, Finland, March 22, 2002 Lecture: “BAALC, the Human Member of a Novel Mammalian Neuroectoderm Gene Lineage, is Implicated in Hematopoiesis and Acute Leukemia.” Major Invited Talks Continued 227. European Society of Human Genetics Mauro Baschirotto Award Lecture, Strasbourg, France, May 28, 2002 Baschirotto Award Lecture 2002: “BAALC, the Human Member of a Novel Mammalian Neuroectoderm Gene Lineage, is Implicated in Hematopoiesis and Acute Leukemia.” 228.The Mildred Scheel Cancer Conference, Gästehaus Petersberg, Germany, September 19, 2002 Keynote Lecture: “Translational Cancer Genetics: From Mismatch Repair Deficiency to Cancer Prevention.” 229.Joint International Journal of Cancer/Meyenburg-Stiftung Lectureship, Heidelberg, Germany, September 23, 2002 Lecture: “Genetic and Epigenetic Predisposition to Colon Cancer.” 230. The American Society of Human Genetics William Allan Award Presentation and Lecture, Baltimore, MD, October 18, 2002 William Allan Award Lecture: “Inherited Human Diseases: Challenges, Victories and Disappointments.” 231.Karolinska Research Lectures at Nobel Forum, The Karolinska Institute, Stockholm, Sweden, November 14, 2002 Lecture: “Population-based Screening for Predisposition to Cancers Caused by Mismatch Repair Deficiency.” 232. Diagnostic Guidelines for Hereditary Non-Polyposis Colorectal Cancer and Microsatellite Instability Meeting, Bethesda, MD, December 12, 2002 Lecture: “Microsatellite Instability Versus Immunohistochemistry in the Screening for Mismatch Repair Deficiency.” 233.Finnish Cancer Foundation 30th Symposium, Helsinki, Finland, February 7, 2003 Lecture: “How Should the Screening and Surveillance of Hereditary Colon Cancer be Organized in Finland.” 234. Folkhälsan Institute of Genetics 40th Anniversary Seminar, Helsinki, Finland, February 14, 2003 Lecture: “Ossian Schauman’s Institute of Genetics.” 235. Folkhälsan Institute of Genetics 40th Anniversary Seminar, Helsinki, Finland, February 14, 2003 Lecture: “The Genetics of Selective Intestinal Malabsorption of Vitamin B12.” 236. Danish Society of Medical Genetics 25th Anniversary Meeting, Copenhagen, Denmark, April 4, 2003 Lecture: “Genetic and Epigenetic Predisposition to Colon Cancer” 237. The Environmental Mutagen Society: “Environmental Mutagenesis: From Mechanisms to Risk Assessment”, Miami, FL, May 14, 2003 Lecture: “Is Large Scale Molecular Screening For Hereditary Colorectal Cancer Feasible?” 238. The Evanston Northwestern Healthcare Inaugural Henry Lynch Lectureship, Evanston, IL, May 30, 2003 Lecture: “A Geneticist’s Perspective on Lynch Syndrome” 239. UICC International Conference: “Family Cancer: Biology & Clinical Care” Oklahoma City, OK, June 5, 2003 Lecture: “Update on HNPCC” 240. 4th Benjamin Franklin Stem Cell Workshop, Berlin, Germany, October 22, 2004 Lecture: “Challenges of ‘New’ Genes: BAALC in Acute Leukemia” 25
  26. 26. Albert de la Chapelle Curriculum Vitae 241.Fox Chase Cancer Institute: Cancer Genetics 2005, Bridging Science to Practice, Philadelphia, PA, March 8, 2005 Lecture: “Genetic Predisposition to Colon Cancer” 242.American Association for Cancer Research 96th Annual Meeting, Anaheim, CA, April 18, 2005 Lecture: “Genetic Predisposition to Colon Cancer” Major Invited Talks Continued 243.Sigrid Jusélius 75th Anniversary Symposium, Helsinki, Finland, June 10, 2005 Lecture: “Genetic Predisposition to Colon Cancer” 244. Wake Forest University School of Medicine: Piedmont Oncology Association Fall Symposium, Myrtle Beach, SC, September 30, 2005 Lecture: “Genes in the Predisposition to Colon Cancer” 245. American Association for Cancer Research, Cancer Susceptibility and Cancer Susceptibility Syndromes, Maui, Hawaii, March 3, 2006 Lecture: “The Genetic Predisposition to Colon Cancer” 246. German Society of Human Genetics Annual Congress, Heidelberg, Germany, March 8, 2006 Lecture: “A proposal to Screen all Clorectal Cancer Patients for Predisposing Mutations” 247. American Society of Clinical Oncology Annual Meeting, Atlanta, GA, June 5, 2006 Lecture: “Hereditary Colorectal Cancer: How to Integrate Testing into Clinical Practice” 248.National Cancer Institute Conference “50 Years of 46 Human Chromosomes: Progress in Cytogenetics” Bethesda, MD, July 21, 2006 Presentation: “Concluding Remarks” 249. The Colon Cancer Family Registry Conference “Etiological Pathways in Colorectal Cancer: Implications for Future Studies”, Santa Monica, CA, September 5, 2006 Presentation: “Mutations in the PMS2 Gene” 250. Siteman Cancer Center, Cancer Genetics Seminar Series, Washington University, St. Louis, MO, February 13, 2007 Presentation: “Colon Cancer Genes” 251. American Association for Cancer Research, Annual Meeting, Los Angeles, CA, April 17, 2007 Lecture: “Genetic Testing for Colorectal Cancer Predisposition” 252. Department of Veterans Affairs. Hereditary Non-Polyposis Colorectal Cancer Advisory Meeting, Washington, DC, September 27, 2007 Presentation: “Screening for Lynch Syndrome” 253. Cancer and Heredity Symposium, University of Groningen, The Netherlands, November 15, 2007 Lecture: “Genes in the Predisposition to Colon Cancer” 254. Centro Nacional de Investigaciones Oncológicas Seminar Series, Madrid, Spain, January 25, 2008 Lecture: “Genes in the Predisposition to Colon Cancer” 255. International Symposium on Cancer Genotypes and Cancer Phenotypes, Florence, Italy, July 5, 2008 Lecture: “Genetic Predisposition to Colorectal Cancer” 256. The Cleveland Clinic Colorectal Cancer Summit, Cleveland, OH, Sept. 4, 2008 Lecture: “Lynch Syndrome” 257. Collaborative Group of the Americas on Inherited Colorectal Cancer 12th Annual Meeting, Cleveland, OH, Sept. 5, 2008 Jagelman Lecture: “The Role of Founder Mutations in Lynch Syndrome” 258. 79th Annual Meeting of The American Thyroid Association, Chicago, IL Oct. 3, 2008 Presentation: “Genes in the Predisposition to Papillary Thyroid Cancer” 26
  27. 27. Albert de la Chapelle Curriculum Vitae 27
  28. 28. Albert de la Chapelle Curriculum Vitae Invited Local Talks, Lectures and Seminars Events Before 1971 Not Listed 1. Symposium on the Regulation of Differentiation, Helsinki, Finland, February 12, 1971 Lecture: "The Use of DNA-RNA Hybridization in the Study of the Mechanisms by which Differentiation is Regulated." (in Finnish) 2. Savonlinna Medical Association, Savonlinna, Finland, February 4, 1972 Lecture: "Modern Genetic Counseling." (in Finnish) 3. Postgraduate Course, Finnish Medical Association and Scientific Associations, Helsinki, Finland, January 13, 1973 Lecture: "Basic Cytogenetics and Cytogenetic Methodology." (in Finnish) 4. Department of Medicine, Kivelä Hospital, Helsinki, Finland, March 16, 1973 Lecture: "Chromosome Investigations from an Internist's Point of View." (in Finnish) 5. Grand Rounds, Aurora Hospital, Helsinki, Finland, October 24, 1973 Lecture: "Fetal Cells in the Maternal Blood." (in Finnish) 6. Finnish Society for Nuclear Technology, Helsinki, Finland, October 25, 1973 Lecture: "Biological Dose Monitoring." (in Finnish) 7. Department of Pathology, University of Oulu, Oulu, Finland, November 30, 1973 Lecture: "Human Chromosomal Inversions." (in Finnish) 8. Department of Sero-Bacteriology, University of Helsinki, Helsinki, Finland, December 14, 1973 Lecture: "Mechanisms of Mammalian Chromosome Banding I". 9. Department of Sero-Bacteriology, University of Helsinki, Helsinki, Finland, January 18, 1974 Lecture: "Mechanisms of Mammalian Chromosome Banding II." 10. Societas Genetica Fennica (Finnish Genetics Society), Annual Meeting, Turku, Finland, February 23, 1974 Lecture: " The Banding of Human Chromosomes". (in Finnish) 11. Tampere Medical Association, Tampere, Finland, March 7, 1974 Lecture: "Chromosome Investigations from a Clinical Point of View." (in Finnish) 12. Postgraduate Course in Haematology, University of Helsinki, Finland, October 4, 1974 Lecture: "Significance of Chromosome Investigations in Haematology." (in Finnish) 13. Satakunta Medical Association, Pori, Finland, October 18, 1974 Lecture: "Indications for Chromosome Study." (in Finnish) 14. Kyminlaakso Medical Association, Lahti, Finland, December 3, 1974 Lecture: "Indications for Chromosme Study." (in Finnish) 15. Finska Läkaresällskapet, Helsinki, Finland, February 6, 1975 Lecture: "Do Chromosome Aberrations in the Bone Marrow Lead to Leukemia?" (in Swedish) 16. Department of Pediatrics, University of Helsinki, Finland, February 12, 1971 Lecture: "Human Gene Mapping." (in Finnish) 17. Grand Rounds, Aurora Hospital, Helsinki Finland, May 7, 1975 Lecture: "Indications for Chromosome Study." (in Finnish) 18. Department of Ophthalmology, University of Helsinki, Finland, May 14, 1975 Lecture: "Basic Human Genetics for Ophthalmologists." (in Finnish) 19. Conference of Nordic Medical Laboratory Group, Helsinki, Finland, May 23, 1975 Lecture: "Indications for Chromosome Study." (in Swedish) 20. University of Turku, Finland, January 26, 1976 Lecture: "The Organization of Clinical Genetics Services." (in Finnish) 21. Finska Vetenskaps-Societeten (The Finnish Academy of Sciences), Helsinki, Finland, February 16, 1976 Lecture: "The Role of Chromosomes in Human Sex Differentiation." (in Swedish) 28
  29. 29. Albert de la Chapelle Curriculum Vitae Invited Local Talks, Lectures and Seminars Continued 22. Grand Rounds, Central Hospital of Kotka, Finland, February 18, 1976 Lecture: "Indications for Chromosome Study." (in Finnish) 23. Course on the Diagnosis of Hereditary Metabolic Diseases Organized by the Finnish Association of Clinical Chemistry and Physiology, Helsinki, Finland, March 13, 1976 Lecture: "The Study of Amniotic Fluid Samples." (in Finnish) 24. Finnish Association of Hematology, Tenth Anniversary Meeting, Helsinki, Finland, April 2, 1976 Lecture: "The Use of Bone Marrow Chromosomal Abnormalities in Human Gene Mapping." 25. Department of Radiochemistry, University of Helsinki, Finland, February 11, 1977 Lecture: "Biologic Dosimetry." (in Finnish) 26. Medical Association of Central Finland, Jyväskylä, Finland, March 23, 1977 Lecture: "Indications for Chromosome Study." (in Finnish) 27. Department of Virology, University of Helsinki, Finland, March 24, 1977 Lecture: "Mapping the Human Chromosomes." 28. Grand Rounds, Departments of Medicine, University of Helsinki, Finland, April 28, 1977 Lecture: "Chromosome Diagnostics in Hematology." (in Finnish) 29. Finnish Society of Endocrinology, 30th Anniversary Meeting, Hyvinkää, Finland, October 14, 1977 Lecture: "The Sex Chromosomes." 30. Course on Treatment of Malignant Hematologic Diseases, University of Helsinki and the Finnish Association of Hematology, Lammi, Finland, October 27, 1977 Lecture: "The Significance of Chromosome Investigations of the Bone Marrow in Leukemia." (in Finnish) 31. Grand Rounds, Department of Surgery, University of Helsinki, Finland, November 25, 1977 Lecture: "Genetics in a Department of Surgery." (in Finnish) 32. Postgraduate Course, Finnish Medical Association and Scientific Associations, Helsinki, Finland, January 10, 1978 Lecture: "Genetics of Chromosomal Disorders." (in Finnish) 33. Postgraduate Course, Finnish Medical Association and Scientific Associations, Helsinki, Finland, January 10, 1978 Lecture: "Control of Genes, Fact or Utopia." (in Finnish) 34. Societas Biochemica, Biophysica et Microbiologica Fenniae (Finnish Society of Biochemistry, Biophysics and Microbiology) Annual Meeting, Helsinki, Finland, February 22, 1978 Lecture: "The Human Gene Map." (in Finnish) 35. Mjölbollsta Hospital, Mjölbollsta, Finland, April 25, 1978 Lecture: "Genetics in a Hospital for Internal Medicine." (in Swedish) 34. Dental Research Day, University of Turku, Finland, September 29, 1978 Lecture: "Medical Genetics and Some of its Details." (in Finnish) 35. Radiation Protection Days, Helsinki, Finland, October 17, 1978 Lecture: "Genetic Effects of Ionizing Radiation." (in Finnish) 38. Course in Clinical Genetics, University of Helsinki, and Finnish Association of Medical Genetics, Lammi, Finland, October 12, 1978 Lecture: "The Molecular Basis of Inheritance and the Human Gene Map." (in Finnish) 39. Course in Clinical Genetics, University of Helsinki, and Finnish Association of Medical Genetics, Lammi, Finland, October 12, 1978 Lecture: "Abnormalities of the Sex Chromosomes." (in Finnish) 40. Molecular Biology Days, Helsinki, Finland, October 26, 1978 Lecture: "Are Testes Induced by Multiple Genes after All? Genealogy and H-Y Antigen." (in Finnish) 29
  30. 30. Albert de la Chapelle Curriculum Vitae Invited Local Talks, Lectures and Seminars Continued 41. Nordic Ecumenic Union, Seminar, Tuusula, Finland, November 17, 1978 Lecture: "Genetic Research To-Day and in the Future." (in Swedish) 42. Fourth Department of Medicine, University of Helsinki, Finland, December 12, 1978 Lecture: "Genetics at a Department of Medicine." (in Swedish) 43 Symposium on Acute Leukemia, Postgraduate Course, Finnish Medical Association and Scientific Associations, Helsinki, Finland, January 12, 1979 Lecture: "Chromosomal Aberrations in Acute Leukemia." 44.Department of Obstetrics and Gynecology, University of Helsinki, Finland, March 16, 1979 Lecture: "The Role of Chromosome Abnormalities in Infertility." (in Finnish) 45.Nordic Symposium organized by the Finnish Association of Pathology, Helsinki, Finland, March 21, 1979 Lecture: "Hereditary Disorders that are Common in Finland." (in Swedish) 46. Critical University, Helsinki, Finland, April 2, 1979 Lecture: "Genetic Research and the Responsibility for Man." (in Finnish) 47. Course on Alternative Approaches to Medicine, Helsinki, Finland, September 28, 1979 Lecture: "What Does Genetics Have to Offer the Physician." (in Finnish) 48. Businessmen's Association, Helsinki, Finland, November 22, 1979 Lecture: "Genetics in the Service of the Community." (in Swedish) 49. Midwifery Hospital, Helsinki, Finland, March 12, 1980 Lecture: "Prenatal Diagnosis in Finland." (in Finnish) 48. Finnish Association of Sports Medicine, Helsinki, Finland, April 11, 1980 Lecture: "The Use and Misuse of Cytologic Methods for the Determination of Sex." (in Finnish) 49. Department of Radiotherapy, University of Helsinki, Finland, September 4, 1980 Lecture: "Chromosome Investigations in Lymphoma." (in Finnish) 52. Finnish Leukemia Group, Turku, Finland, September 26, 1980 Lecture: "Chromosome Investigations in Myeloma." (in Finnish) 53. Symposium on Endocrinology of Puberty. Postgraduate Courses, Finnish Medical Association and Scientific Associations, Helsinki, Finland, January 9, 1981 Lecture: "Genetic Determination of Maleness." 54. Symposium on Chemotherapy, Finnish Cancer Foundation, Tuusula, Finland, February 14, 1981 Lecture: "Genetic Late Effects of Cytostatic Drugs." 55. Department of Radiotherapy, University of Helsinki, Finland, February 27, 1981 Lecture: "Chromosome Investigations of Tumors." 56. Course on Lymphoma, Finnish Association of Hematology, Lammi, Finland, October 21, 1982 Lecture: "Specific Translocations and Their Significance in the Etiology and Diagnosis of Burkitt's Lymphoma." (in Finnish) 64. Seminars in Clinical Genetics, University of Helsinki, Finland, November 12, 1982 Lecture: "The Etiology of XX Males." (in Finnish) 58. Finska Vetenskaps-Societeten (Finnish Academy of Sciences), Helsinki, Finland, January 17, 1983 Lecture (as a recipient of the E.J. Nyström Prize): "Modern Genetics at the Service of Medicine." (in Swedish) 59. Department of Medicine, University of Turku, Finland, April 13, 1983 Lecture: "What's New in the Chromosomes of Leukemias and Tumors." (in Finnish) 60. Department of Pediatrics, University of Turku, Finland, April 13, 1983 Lecture: "Present-Day Indications for Chromosome Study." (in Finnish) 61. Department of Biochemistry, University of Helsinki, Helsinki, Finland, April 29, 1983 Lecture: "In situ DNA Hybridization." 30

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