Biochemistry
The Biochemistry program at Bishop’s is coordinated through an interdisciplinary committee of
chemists, bioch...
The Biochemistry Programs
Biochemistry Major - Concentration Biology
The Biochemistry Major program is a three-year progra...
BIO 310 Advanced Cell Biology                  CHE 226 Interm. Org. Chem. II (L)               CHE      227
Chem. Spectros...
BIL 352a Microbiology Laboratory
Two Options
3rd Year
(5 courses-15 credits/1 laboratory)                                 ...
CHE 105a Organic Chemistry I: Introductory                  CHE 186b Organic Chemistry
Laboratory II
CHE 185a Organic Chem...
Biochemistry Honours - Concentration Chemistry
The Biochemistry Honours program is a three-year program that prepares a st...
BIO 291a Biometry/BIL291a Biometry Lab                             Four Options
BCH 370a Molecular Genetics
BCH 461a Enzym...
BCH 370a is a cross-listed course with BIO 360a. BCH 374b/BCH 384b is a cross-listed course with
BIO314b/BIL314b.
Biochemistry 101b Introduction to Nutrition               3-3-0
This course is designed for students from any discipline (...
This course will introduce students to Bioinformatics, which uses computer databases to store, retrieve and assist in
unde...
Professor Prusak
Biochemistry 483a/b Honours Research Project II         3-1-12
A continuation of Biochemistry 482, consis...
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Biochemistry

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Biochemistry

  1. 1. Biochemistry The Biochemistry program at Bishop’s is coordinated through an interdisciplinary committee of chemists, biochemists and biologists. It offers degree options in two separate streams, a concentration Chemistry which provides a strong background in Chemistry and a concentration Biology, which provides a strong background in both biology and chemistry applicable to students looking to continue in the health or life sciences. Both streams offer an Honours degree, which rigorously prepares students for graduate studies or for professional schools, and a Majors degree, which provides students more flexibility in their program. The program places strong emphasis on mastering the fundamentals of experimental biochemistry, and provides students with well equipped laboratory facilities, first-hand experience with modern laboratory equipment, and close instructional contact with professors. As well, the Agriculture Canada Research Station in Lennoxville and the Université de Sherbrooke, with its associated medical research hospital, are easily accessible to students and provide additional opportunities and exposure for interested Honours students. Entrance Requirements To enter a three-year Biochemistry program, a student must have a Quebec collegial diploma (D.E.C.) in science, or the equivalent, including Mathematics NYA, NYB, Physics NYA, NYB, Chemistry NYA, NYB, and Biology NYA. Students entering a degree program with CEGEP Chemistry BFA and Chemistry BFB are exempted from Chemistry 105a and 185a but must include Chemistry 106b and 186b plus an additional one-semester chemistry or biochemistry lecture course in their program; students entering a degree program with CEGEP Chemistry BFA only, must include Bishop’s Chemistry 105a, 185a, 106b, and 186b in their program. Students entering four-year degree programs (after completion of Ontario OSSD, grade 12 in other provinces or the USA, or equivalent) must register in the required collegial equivalent science courses (Chemistry 191/081 and 192/082, Mathematics 198/088 and 199/089, Physics 193/083 and 194/084, and Biology/Biology Laboratory191. Those students who intend to take mathematics and physics courses at the University level are advised to replace Mathematics 198/088 by Mathematics 191/081, and Mathematics 199/089 by Mathematics 192/082, Physics 193/083 by Physics 191/081, and Physics 194/084 by Physics 192/082. All students entering four-year degree programs must also register in their first year for English Language 116, or another English course, and an additional three-credit course which must be selected from Humanities courses in English, History, Classical Studies, Philosophy, Religion, or Liberal Arts. Students in four-year programs must complete a total of ten one-semester lecture courses plus all co-requisite laboratory courses to complete this U0 year. Requirements for Honours Programs Students are not admitted to an Honours Biochemistry program until the end of U2 year. To be eligible to enter the Honours Biochemistry programs, concentration Biology or Chemistry, a student must normally achieve: i) a minimum cumulative average of 75% by the end of the U2 year, and ii) at least 75% in each course required in the program. To complete an Honours Biochemistry program, a student must; i) maintain a minimum cumulative average of 75% and ii) achieve at least 75% in each course required in the program with a maximum permitted exemption of four credits. The programs also include a six-credit honours research project that will be evaluated by at least three faculty from the Biochemistry Program Committee. The scientific results of the honours research project must be presented in a public, oral seminar and submitted in a written thesis.
  2. 2. The Biochemistry Programs Biochemistry Major - Concentration Biology The Biochemistry Major program is a three-year program that requires 30 three-credit one-semester courses, or their equivalent, for a total of 90 course credits, plus 10 credits for associated laboratory courses, for a total of 100 credits overall. The 90 course credits are divided as follows: 15 course credits of required chemistry (plus 5 laboratory credits), 12 course credits of required biology (plus 3 laboratory credits), 12 course credits of required biochemistry (plus 2 laboratory credits), 3 course credits of required physics, 18 course credits of required options in chemistry, biology or biochemistry (plus any co-requisite laboratory courses), 30 credits of options. The program is under the supervision of the Biochemistry Committee; enquiries and questions concerning the program should be directed to the Director of the Biochemistry Program. The normal sequence of courses in the program is shown below. Students must, however, consult with the director before registration. 1st Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /3 laboratories) BIO 110a Introductory Cellular & Molecular Biology BIO 118b Genetics CHE 103b Physical Chemistry I BIL 118b Genetics Laboratory CHE 183b Physical Chemistry Laboratory I CHE 102a Inorganic Chemistry I CHE 104a Analytical Chemistry BCH 211b Biochemistry I CHE 184a Analytical Chemistry Laboratory CHE 106b Organic Chemistry II: Introductory CHE 105a Organic Chemistry I: Introductory CHE 186b Organic Chemistry Laboratory II CHE 185a Organic Chemistry Laboratory I CHE 189b Instrumental Analysis Laboratory I PHY 101a Statistical Methods One Option 2nd Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits/1 laboratory) BCH 212a Biochemistry II BCH 275b Biochemistry III BCH 281a Analytical Biochemistry Laboratory I BCH 282b Analytical Biochemistry Lab II BIO 226a Animal Physiology I Four Options BIL 226a Animal Physiology Laboratory I BIO 352a Microbiology BIL 352a Microbiology Laboratory Two Options 3rd Year (5 courses-15 credits) (5 courses-15 credits) BCH 370a Molecular Genetics Five Options Four Options Required Optional Courses (6 from the list): Biology: Biochemistry: Chemistry: BIO 228 Animal Physiology II (L) BCH 336 Immunology CHE 144 Environmental Chem I BIO 252 Bioethics BCH 338 Environm. Toxicology CHE 223 Chem. Spectroscopy (L) BIO 291 Biometry (L) BCH 341 Current Topics in Biotechnology CHE 225 Interm. Org. Chem. I (L)
  3. 3. BIO 310 Advanced Cell Biology CHE 226 Interm. Org. Chem. II (L) CHE 227 Chem. Spectroscopy (L) BIO 320 Programmed Cell Death BCH 374 Biotechnology (L) CHE 244 Environmental Chem II (L) BIO 328 Adv. Animal Physiology BCH 380 Psychopharmacology BIO 345 Plant Physiology BCH 461 Enzymology BIO 365 Developmental Biology Free Electives (10) Recommended Free Elective Course: BIO 212 Evolution BIO 379 Clinical Neuropsychology PHI 245 The Philosophy of Science Biochemistry Honours - Concentration Biology The Biochemistry Honours program is a three-year program that prepares a student for graduate studies in biochemistry and related disciplines, for Medicine and Dentistry, as well as for direct professional employment. The program requires 30 three-credit one-semester courses, or their equivalent, for a total of 90 course credits, plus 11 credits for associated laboratory courses, for a total of 99 credits overall. The 90 course credits are divided as follows:- 15 course credits of required chemistry (plus 5 laboratory credits), 18 course credits of required biology (plus 4 laboratory credits), 21 course credits of required biochemistry (plus 2 laboratory credits), 3 course credits of required physics, 15 course credits of required options in chemistry, biology or biochemistry (plus any co- requisite laboratory courses), 18 credits of options. The program is under the supervision of the Biochemistry Committee; enquiries and questions concerning the program should be directed to the Director of the Biochemistry Program. The normal sequence of courses in the program is shown below. Students must however, consult with the director before registration. 1st Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /3 laboratories) BIO 110a Introductory Cellular & Molecular Biology BIO 118b Genetics CHE 103b Physical Chemistry I BIL 118b Genetics Laboratory CHE 183b Physical Chemistry Laboratory I BCH 211b Biochemistry I CHE 104a Analytical Chemistry CHE 102a Inorganic Chemistry I CHE 184a Analytical Chemistry Laboratory CHE 106b Organic Chemistry II: Introductory CHE 105a Organic Chemistry I: Introductory CHE 186b Organic Chemistry II: Laboratory II CHE 185a Organic Chemistry Laboratory I CHE 189b Instrumental Analysis Laboratory I PHY 101a Statistical Methods One Option 2nd Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /1 laboratory) BCH 212a Biochemistry II BCH 275b Biochemistry III BCH 281a Analytical Biochemistry Laboratory I BCH 282b Analytical Biochemistry Lab II BIO 226a Animal Physiology I Four Options BIL 226a Animal Physiology Laboratory I BIO 352a Microbiology
  4. 4. BIL 352a Microbiology Laboratory Two Options 3rd Year (5 courses-15 credits/1 laboratory) (5 courses-15 credits) BIO 272a Scientific Writing BCH 483a/b Research Project II BIO 291a Biometry Four Options BIL 291a Biometry Lab BCH 370a Molecular Genetics BCH 461a Enzymology BCH 482a/b Research Project I Required Optional Courses (5 from the list): Biology: Biochemistry: Chemistry: BIO 228 Animal Physiology II (L) BCH 336 Immunology CHE 144 Environmental Chem. I BIO 252 Bioethics BCH 338 Environm. Toxicology CHE 223 Physical Chem. II (L) BIO 310 Advanced Cell Biology BCH 341 Current Topics in Biotechnology CHE 225 Interm. Org. Chem. I (L) BIO 320 Programmed Cell Death BCH 374 Biotechnology (L) CHE 226 Interm. Org. Chem. II (L) BIO 328 Adv. Animal Physiology BCH 380 Psychopharmacology CHE 227 Chem. Spectroscopy (L) BIO 345 Plant Physiology CHE 244 Environmental Chem. II (L) BIO 359 Human Genetics BIO 365 Developmental Biology Free Electives (6) Biochemistry Major - Concentration Chemistry The Biochemistry Major program is a three-year program that requires 30 three-credit one-semester courses, or their equivalent, for a total of 90 course credits, plus 13 credits for associated laboratory courses, for a total of 103 credits overall. The 90 course credits are divided as follows:- 30 course credits of required chemistry (plus 9 laboratory credits), 9 course credits of required biology (plus 2 laboratory credits), 15 course credits of required biochemistry (plus 2 laboratory credits), 15 course credits of required options in chemistry, biology or biochemistry (plus any co-requisite laboratory courses), 24 credits of options. The program is under the supervision of the Biochemistry Committee; enquiries and questions concerning the program should be directed to the Director of the Biochemistry Program. The normal sequence of courses in the program is shown below. Students must however, consult with the director before registration. 1st Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /4 laboratories) BIO 110a Introductory Cellular & Molecular Biology BIO 118b Genetics CHE 103b Physical Chemistry I BIL 118b Genetics Laboratory CHE 183b Physical Chemistry Laboratory I BCH 211b Biochemistry I CHE 104a Analytical Chemistry CHE 102a Inorganic Chemistry I CHE 184a Analytical Chemistry Laboratory CHE 106b Organic Chemistry II: Introductory
  5. 5. CHE 105a Organic Chemistry I: Introductory CHE 186b Organic Chemistry Laboratory II CHE 185a Organic Chemistry Laboratory I CHE 189b Instrumental Analysis Laboratory I One Option CHE 223a Physical Chemistry II CHE 283a Physical Chemistry Laboratory II Note: CHE 223 can be taken in the 2nd year 2nd Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /2 laboratories) BCH 212a Biochemistry II BCH 275b Biochemistry III BCH 281a Analytical Biochemistry Laboratory I BCH 282b Analytical Biochemistry Lab II CHE 227a Chemical Spectroscopy CHE 224b Physical Chemistry III CHE 287a Chemical Spectroscopy Laboratory CHE 226b Intermediate Organic Chemistry II CHE 225a Intermediate Organic Chemistry I CHE 386b Intermediate Organic Chem. Laboratory II CHE 385a Intermediate Organic Chem. Laboratory I Two options Two Options Note: CHE 224 can be taken in the 3rd year 3rd Year (5 courses-15 credits /1 laboratory) (5 courses-15 credits) BIO 226 Animal Physiology I Five Options BIL 226 Animal Physiology Laboratory I BCH 370a Molecular Genetics Three options Required Optional Courses (5 from the list): Biology: Biochemistry: Chemistry: BIO 228 Animal Physiology II (L) BCH 336 Immunology CHE 144 Environmental Chem I BIO 310 Advanced Cell Biology BCH 338 Environm. Toxicology CHE 221 Inorganic Chem. II (L) BIO 320 Programmed Cell Death BCH 380 Psychopharmacology CHE 244 Environmental Chem. II (L) BIO 345 Plant Physiology BCH 341 Current Topics in Biotechnology CHE 464 Computational Chem. BIO 352 Microbiology (L) BCH 374 Biotechnology (L) BIO 359 Human Genetics BCH 461 Enzymology BIO 365 Developmental Biology Free Electives (8) Recommended Free Elective Course: BIO 212 Evolution BIO 379 Clinical Neuropsychology PHI 245 The Philosophy of Science
  6. 6. Biochemistry Honours - Concentration Chemistry The Biochemistry Honours program is a three-year program that prepares a student for graduate studies in biochemistry and related disciplines, for Medicine and Dentistry, as well as for direct professional employment. The program requires 30 three-credit one-semester courses, or their equivalent, for a total of 90 course credits, plus 15 credits of associated laboratory courses, for a total of 105 credits. The 90 course credits are divided as follows:- 33 course credits of required chemistry (plus 10 laboratory credits), 15 course credits of required biology (plus 3 laboratory credits), 24 course credits of required biochemistry (plus 2 laboratory credits), 18 credits of options. The program is under the supervision of the Biochemistry Committee; enquiries and questions concerning the program should be directed to the Director of the Biochemistry Program. The normal sequence of courses in the program is shown below. Students must however, consult with the director before registration. 1st Year (5 courses-15 credits /3 laboratories) (5 courses-15 credits /4 laboratories) BIO 110a Introductory Cellular & Molecular Biology BIO 118b Genetics CHE 103b Physical Chemistry I BIL 118b Genetics Laboratory CHE 183b Physical Chemistry Laboratory I BCH 211b Biochemistry I CHE 104a Analytical Chemistry CHE102b Inorganic Chemistry I CHE 184a Analytical Chemistry Laboratory CHE 106b Organic Chemistry II: Introductory CHE 105a Organic Chemistry I: Introductory CHE 186b Organic Chemistry Laboratory II CHE 185a Organic Chemistry Laboratory I CHE 189b Instrumental Analysis Laboratory I One Option CHE 223a Physical Chemistry II CHE 283a Physical Chemistry Laboratory II Note: CHE 223 can be taken in the 2nd year 2nd Year (5 courses-15 credits /5 laboratories) (5 courses-15 credits /2 laboratories) BIO 226 Animal Physiology I BCH 275b Biochemistry III BIL 226 Animal Physiology Laboratory I BCH282b Analytical Biochemistry Lab II BCH 212a Biochemistry II BCH 336 Immunology BCH 281a Analytical Biochemistry Laboratory I BCH 224b Physical Chemistry III CHE 221a Inorganic Chemistry II CHE 226b Intermediate Organic Chemistry II CHE 281a Inorganic Laboratory II CHE 386b Intermediate Organic Chemistry II CHE 227a Chemical Spectroscopy One Option CHE 287a Chemical Spectroscopy Laboratory Note: CHE 224 and BCH 336 can be taken in the 3rd year CHE 225a Intermediate Organic Chemistry I CHE 385a Intermediate Organic Chem. Laboratory I Note: CHE 221 can be taken in the 3rd year 3rd Year (5 courses-15 credits /1 laboratory) (5 courses-15 credits) BIO 272a Scientific Writing BCH 483a/b Research Project II
  7. 7. BIO 291a Biometry/BIL291a Biometry Lab Four Options BCH 370a Molecular Genetics BCH 461a Enzymology BCH 482a/b Research Project I Free Electives (6) Biochemistry Minor This program is intended for students who are not registered in the Department of Chemistry. The program requires 8 three-credit one-semester courses, or their equivalent, for a total of 24 course credits, plus credits for associated laboratory courses. Required Courses: (5 courses - 15 credits, plus 4 laboratory credits) BIO 110a Introductory Cellular & Molecular Biology BCH 211b Biochemistry I: Proteins BCH 281b Analytical Biochemistry Laboratory I BCH 275b Biochemistry III: Metabolism BCH 282a Introductory Biochemistry Laboratory II CHE 104a Analytical Chemistry CHE 184a Analytical Chemistry Laboratory CHE 105a Organic Chemistry I: Introductory CHE 185a Organic Chemistry Laboratory I Required Optional Courses (3 from the list): Chemistry: CHE 103 Physical Chemistry I (L) CHE 106 Organic Chemistry II: Introductory (L) Biochemistry: BCH 212 Biochemistry II: Lipids and Biomembranes BCH 336 Immunology BCH 370 Molecular Genetics BCH 380 Psychopharmacology BCH 461 Enzymology Biology: BIO 218 Genetics (L) BIO 226 Animal Physiology I (L) BIO 228 Animal Physiology II (L) BIO 252 Bioethics BIO 320 Programmed Cell Death BIO 345 Plant Physiology BIO 352 Microbiology (L) Course Prerequisites The normal prerequisites for each course are listed. Students not having the appropriate prerequisite may be admitted to a course with permission of the instructor. Cross-Listed Courses Students can receive credits only once for any courses that are cross-listed between Biochemistry, Biology and/or Neuroscience. BCH 275b is a cross-listed course with BIO 215b. BCH 380b is a cross-listed course with PBI 380b and BIO 380b. BCH282b is a cross-listed course with BIL 215b.
  8. 8. BCH 370a is a cross-listed course with BIO 360a. BCH 374b/BCH 384b is a cross-listed course with BIO314b/BIL314b.
  9. 9. Biochemistry 101b Introduction to Nutrition 3-3-0 This course is designed for students from any discipline (except Biochemistry, Biology and Chemistry). It will provide an introduction to basic concepts of nutrition and ways that good nutrition can be integrated into a healthy life style. Principles of digestion and absorption, the function of nutrients, disease prevention, diet modification and weight control will be discussed. Prerequisites: None. However, secondary school Biology is strongly recommended. Note: This course may not be taken for credit by students in Biology, Biochemistry or Chemistry programs. Biochemistry 192b Biochemistry of Macromolecules3-1-3 Introduction to biochemistry with the emphasis on the structure and function of proteins, lipids, carbohydrates and nucleic acids. Prerequisites: Chemistry 191 and Biology 191. Biochemistry 211a Biochemistry I - Proteins 3-3-0 Protein structure and function, including protein purification, structure analysis, protein synthesis, distribution and degradation, as well as molecular visualization of protein structure. Prerequisite: Chemistry 105a/185a, Biology 110a Co-requisite: Chemistry 106b/186b, Chemistry 189 Professor Prusak Biochemistry 212b Biochemistry II - Lipids and Biomembranes 3-3-0 Biomembranes structure and function, including study of cell membrane structure, trans-membrane signaling, hormones and secondary messengers. Prerequisite: Biochemistry 211b Co-requisite: Biochemistry 281a Professor Prusak Biochemistry 275b Biochemistry III - Metabolism 3-3-0 Introduction to the basic metabolic pathways of living cells. These include the central metabolic pathways associated with cellular energy generation, carbohydrate degradation and synthesis, fatty acid degradation and synthesis, lipid metabolism and nitrogen metabolism. Emphasis will be placed on the role and regulation of enzymes associated with these pathways. See Biology 215b Students may not take this course for credit if they have received credit for BIO 215b Prerequisite: Biochemistry 211a and Biochemistry 212a/281a Co-requisite: Biochemistry 282b Professor Stroeher Biochemistry 281a Analytical Biochemistry Laboratory I 1-0-3 This course, together with BCH 282a, will introduce the basic concepts of isolation and identification of biomolecules, the use of chromatography, electrophoresis, and the enzymatic techniques for the quantization of metabolites. Co-requisite: Biochemistry 212a See CHE 189b Students may not take this course for credit if they have received credit for CHE 189b. Professor Wood Biochemistry 282b Analytical Biochemistry Laboratory II 1-0-3 This course, together with BCH 281b, will introduce the basic concepts of protein isolation and identification; the use of high pressure, thin layer and gas/liquid chromatography, and enzymatic techniques for the quantitation of metabolites. Co-requisite: Biochemistry 275b Professor Prusak Biochemistry 336b Immunology 3-3-0 A comprehensive study of the fundamental principles of immunobiology. Intercellular recognition and self/non-self discrimination. Clonal selection theory and genetic basis of antibody diversity. Biochemistry of immunoglobulins. Regulation of immune response and tolerance. Prerequisites: Biology 110a and Biology 118b/Biology Lab 118b Professor Prusak Biochemistry 338b Environmental Biochemistry and Toxicology 3-3-0 This course will examine the biochemical effects of environmental stresses on organisms, and adaptations that allow organisms to face these stresses. Emphasis is placed on biochemical responses to toxic compounds such as aromatics, halogenated aliphatics, drugs, and heavy metals. Other topics will include adaptations to stresses such as temperature extremes, pathogens, and ionizing radiation. Applications to related biotechnological processes may also be considered. Prerequisite: Biology 110a and Biology 118b/ Biology Lab 118b Professor Prusak Biochemistry 341b Current Topics in Biotechnology 3-3-0 Seminar style course in which students will explore the current topics in biotechnology. Prerequisites: Biochemistry 370 Biochemistry 342b Bioinformatics 3-1-3
  10. 10. This course will introduce students to Bioinformatics, which uses computer databases to store, retrieve and assist in understanding biological information. Prerequisites: Biochemistry 370 Biochemistry 370a Molecular Genetics 3-3-0 The molecular biology of nucleic acids and proteins, including DNA replication, mutation, and recombination; RNA transcription; and protein synthesis. Also covered will be protein/nucleic acid interactions and regulation of gene expression. See Biology 360a Students may not take this course for credit if they have received credits for BIO 360a Prerequisite: Biology 118b, Biochemistry 211b and Biochemistry 212a Professor Stroeher Biochemistry 371a Independent Studies in Biochemistry I 3-1-3 This course is not regularly offered and is only meant for final-year students who wish to pursue in-depth study of a particular area of biochemistry or who have a special need for a biochemistry course that would otherwise not be available during their final semester of course work. This course can only be done in close collaboration with a faculty advisor from within the Biochemistry program, and may not be used as a supplement to a student’s honours project. Requirements for this course will be agreed upon by at least three professors from within the Biochemistry Program. Prerequisite: Consent of members of the Biochemistry Program. Biochemistry 372b Independent Studies in Biochemistry II 3-1-3 This course represents an additional semester of independent work, either a continuation of or a separate course from Bch 371a, meant for final-year students who wish to pursue in-depth study of a particular area of biochemistry or who have a special need for a biochemistry course that would otherwise not be available during their final semester of course work. This course can only be done in close collaboration with a faculty advisor from within the Biochemistry Program, and may not be used as a supplement to a student’s honours project. Requirements for this course will be agreed upon by at least three professors from within the Biochemisty Program. Prerequisite: Consent of members of the Biochemistry Program. Biochemistry 374b Biotechnology 3-3-0 This course will explore the technical approaches used in current research and biotechnology, emphasizing the applications of molecular strategies and processes studied in Biology 360/Biochemistry 370. Both the theoretical and practical aspects of these molecular approaches will be discussed, as well as how these techniques are utilized and how they have changed modern research and medicine. Prerequisite: Biology 360a or Biochemistry 370a Corequisite: Biochemistry 384b Professor Stroeher Biochemistry 380b Psychopharmacology 3-3-0 This course is designed to introduce students in psychology and the natural sciences to the field of psychopharmacology. Emphasis will be placed on the relationships between psychoactive drugs, their mechanisms of action in the nervous system, and human behavior. Following an analysis of the principles of pharmacology and pharmacokinetics, as well as the mechanisms of drug tolerance and dependence, the cognitive, emotional and behavioral aspects of specific classes of drugs will be examined. These classes of drugs will include sedatives, hypnotics, stimulants, narcotics, psychotomimetics, psychedelics, and hallucinogens. Students who have taken PBI 280 or BIO 280 (Psychopharmacology) may not take this course for credit Prerequisite: PBI288b or permission of the instructor Professor Drumheller Biochemistry 384b Biotechnology Laboratory 1-0-3 Practical application of several of the techniques introduced in Biochemistry 374b. Prerequisite: Biology 360a or Biochemistry 370a Corequisite: Biochemistry 374b Professor Stroeher Biochemistry 461a Enzymology 3-3-0 Kinetics of enzyme reactions and mechanism of catalysis. Regulation by allosteric effectors and covalent modification. Protein targeting and degradation. Prerequisites: Biochemistry 211b, 212a and 275b Professor Prusak Biochemistry 482a/b Honours Research Project I 3-1-6 An introduction to the planning, execution and reporting of biochemical research. Students are required to choose a research project and in consultation with an approved supervisor, draw up a formal research proposal of work to be undertaken. The proposal must be submitted in final form by November 1or (February 1 for winter semester). The final mark in this course will be based on the research proposal, a written report of the results of the initial experiments as outlined in the proposal and a poster presentation. Satisfactory completion of Biochemistry 482 with a minimum mark of 70% will permit enrolment in Biochemistry 483a/b. Prerequisite: Permission of course coordinator Co-requisite: Biology 272a
  11. 11. Professor Prusak Biochemistry 483a/b Honours Research Project II 3-1-12 A continuation of Biochemistry 482, consisting of experimentation as outlined in the research proposal; presentation of a seminar based on research findings, to be scheduled in the last two weeks of term; and submission of a written dissertation on or before the last day of classes. Prerequisite: Biochemistry 482a/b and permission of course coordinator. Professor Prusak

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