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AND MEDICAL GENETICS

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  • 1. 1 DEPARTMENT OF BIOCHEMISTRY AND MEDICAL GENETICS COURSE OFFERINGS 2010-2011 NOTE: ALL COURSES ARE GIVEN ON THE HEALTH SCIENCES CAMPUS WITH THE EXCEPTIONS OF BGEN 3020 WHICH IS GIVEN ON THE FORT GARRY CAMPUS. STUDENTS WISHING TO REGISTER FOR THESE COURSES SHOULD CONTACT THE RESPONSIBLE INSTRUCTOR OR COURSE CO- ORDINATOR AS SOON AS POSSIBLE. COURSES OFFERED An introductory course in General Biochemistry or Genetics and consent of course directors are prerequisites for the courses listed unless otherwise indicated. All courses listed are not necessarily given each year and a minimum enrolment is required for some courses to be offered. Maximum Course CR HRS. TITLE Coordinator enrollment # CRN# Instructor UNDERGRADUATE COURSES BGEN 3020 Fall Term: INTRODUCTION TO HUMAN GENETICS: Principles necessary to Coordinator: 24 understand and study genetically controlled malformations and diseases Dr. D. Merz 6 CREDIT HRS and variation in individuals and in populations. Two terms. Lectures, # 11687 tutorials and assignments. Not to be held with the former 80.301 or Will be offered 125.301. (Held at Fort Garry Campus. Graduate students wishing to take this course should consult with Dr. D. Merz) 20 BGEN 4010 Fall Term: PROJECT COURSE IN HUMAN GENETICS: A research project chosen in Coordinator: consultation with and supervised by a Faculty member. A written report is Dr. R. D. Gietz 6 CREDIT HRS required. The course is available primarily to the 4 th year students in the # 11696 Honours Genetics program. Will be offered GRADUATE COURSES 25 BGEN 7020 Winter Term: PROTEINS: Three hours per week, one term. Purification, bioinformatics, Coordinator: characterization, expression, structure, folding, and engineering of proteins. Dr. S. Pind NOT OFFERED 10 BGEN 7030 Winter Term: ENZYMOLOGY: Two hours per week, one term. Kinetics and mechanism Coordinator: of action of enzymes. TBA NOT OFFERED 10 BGEN 7040 Winter Term: SEMINARS IN HUMAN GENETICS: Current research topics in human Coordinator: genetics. A term paper and oral presentation will be required of each TBA student. Prerequisite: Consent of Instructor NOT OFFERED 10 BGEN 7090 Fall Term: PRINCIPLES AND PRACTICE OF HUMAN GENETICS: Lectures, tutorials Coordinator: and assignments designed to review major topics in human genetics and Dr. B. Chodirker
  • 2. 2 3 CREDIT HRS. give practical experience in the analysis and interpretation of human # 11718 genetics data and critical review of published work. Prerequisite: Consent Offered only if of Instructor there are two or more registrants 10 BGEN 7120 Winter Term: LABORATORY METHODS IN HUMAN AND MEDICAL GENETICS: Coordinator: A seminar and assignment course covering and outline of the methods currently in use in human and medical genetic diagnostic and research TBA laboratories. The principles of cell culture, cytogenetic, molecular and biochemical genetic techniques that are used in the diagnosis of human NOT OFFERED genetic disease and the study of human variation will be reviewed. Students will undertake a practical assignment and write a report. Prerequisite: BGEN7090 or consent of instructor 10 BGEN 7130 Fall Term: GENETIC EPIDEMIOLOGY OF HUMAN POPULATIONS: Instructor: Lectures, tutorials and assignments to evaluate the etiology, distribution TBA and control of disease in groups of relatives and inherited causes of disease in populations. Prerequisite: BGEN7090 or consent of Instructor NOT OFFERED 10 BGEN 7140 Fall Term: CLINICAL GENETICS: Focus is on clinical application and principles of Instructor: single gene, multifactorial and teratogenic causes of disease. Students will Winter Term: learn by use of reading assignments, tutorials, computer-assisted TBA diagnostic tools and first hand experience in genetics clinics. Major term paper required. Prerequisite: BGEN7090 or consent of Instructor NOT OFFERED 10 BGEN 7160 Winter Term: THEORY AND PRACTICE OF GENETIC COUNSELLING: Review of Instructor: general theoretical and practical aspects of genetic counselling. Students TBA will be instructed in interviewing techniques. Case presentations will be reviewed and opportunities to observe and partake in genetic counselling NOT OFFERED will be provided. Term paper. Prerequisite: BGEN7090 or consent of instructor. 10 BGEN 7180 Winter Term: CLINICAL AND MOLECULAR CYTOGENETICS: Cytogenetic Instructor: methodology; chromosome architecture; karyotype interpretation; Dr. A. Dawson indications for referral; chromosome syndromes and anomalies; prenatal diagnosis; chromosomal basis of oncogenesis; flow cytometry; immunogenetics; fluorescent in situ hybridization; the application of NOT OFFERED molecular technology to chromosome analysis. Prerequisite: BGEN7090 or consent of Instructor 10 BGEN 7200 Fall Term: TOPICS IN BIOCHEMISTRY I: Advanced study and reading on two topics Coordinator: chosen by the course director in consultation with the student’s supervisor. Dr. G. Arthur 3 CREDIT HRS. Topics include but are not limited to Neurochemistry, Lipids, Carbohydrates, # 11719 Biomembranes, Inborn Errors, Cystoskeleton Proteins. Will be offered 5 BGEN 7210 Winter Term: TOPICS IN BIOCHEMISTRY II: Advanced study and reading on two Coordinator: topics chosen by the course director in consultation with the student’s Dr. G. Arthur supervisor. Topics include but are not limited to Neurochemistry, Lipids, Carbohydrates, Biomembranes, Inborn Errors, Cystoskeleton Proteins. Will be offered BGEN 7000 1 CREDIT HR RESEARCH SEMINAR: A one credit pass/fail course. Consists of the Coordinator: (M.Sc.) student’s current research. Dr. E. Leygue 10 Fall Term: A02 # 13022 Please read the seminar regulations posted on the web Registration http://www.umanitoba.ca/faculties/medicine/biochem/programs/graduate/ind mandatory for all 30 Full Term: A01 ex.html students #13009
  • 3. 3 25 BGEN 7250 Winter Term: GENE EXPRESSION: Three hours per week, one term. Chromatin Coordinator: structure. Structure and function of sequence-specific DNA binding Dr. J. Davie CRN # NOT proteins. Control of transcription. AVAILABLE Will be offered 25 BGEN 7260 Fall Term: CELLULAR AND MOLECULAR BIOCHEMISTRY: Three hours per week, Coordinator: one term. Recent research advances on the study of cellular components, Dr. G. Arthur assembly and organization of plasma membrane components, cell signalling, and cell cycle. NOT OFFERED BGEN 8000 1 CREDIT HR RESEARCH SEMINAR: A one credit pass/fail course. Consists of the Coordinator: (PhD) student’s current research. Dr. E. Leygue 10 Fall Term: A02 # 13023 Please read the seminar regulations posted on the web Registration http://www.umanitoba.ca/faculties/medicine/biochem/programs/graduate/ind mandatory for all 30 Full Term: A01 ex.html students #13008 IMED 7090 Full Term: A01 CELL BIOLOGY: Comprehensive introduction to the structure and function Instructor: of cells. Prerequisite: Consent of Instructor Dr. R. Shiu 6 CREDIT HRS #11620 Will be offered IMED Full Term: FUNDAMENTALS OF NEUROSCIENCE An interdepartmental Coordinator: 7100 multidisciplinary course providing a comprehensive overview of cellular, Dr. D. Eisenstat 6 CREDIT HRS. molecular, developmental and systems neuroscience, as well as the Dr. B. Fedirchuk neurobiology of disease. Emphasis will be placed on the application of the # 15163 fundamental principles of neuroscience to contemporary lab research. Will be offered : ANAT 7270 (or 080.727) (offered in alternate years) will provide instruction in neuroanatomy and structure-function in the nervous system. Prerequisite: Permission of instructor 9 IMED 7200 Winter Term: CANCER BIOLOGY Coordinator: One hour per week on the basic (cellular and molecular) and clinical Dr. M. Mowat (diagnostic and treatment) aspects of cancer. Students will give one seminar and submit an essay on an assigned topic. Prerequisite: consent NOT OFFERED of instructor. 25 IMED 7240 Fall Term: NUCLEIC ACIDS: MANIPULATION, STRUCTURE AND FUNCTION: Coordinator: Three hours per week, one term. DNA technology; nucleic acid Dr. L. Murphy 3 CREDIT HRS. metabolism, including DNA replication, DNA repair, transcription, and RNA processing; gene/chromosome structure and rearrangement; mutation Will be offered CRN # NOT detection; gene therapy; positional cloning; transgenic animals. AVAILABLE 20 IMED 7290 Fall Term: DEVELOPMENTAL BIOLOGY: Emphasize current principles of organ Coordinator: system development and its application to transgenic approaches to gene Dr. G. Hicks 3 CREDIT HRS. function in the context of a whole, developing organism. Prerequisite: Dr. J. Wigle # 15168 165.709 or 022.215 and/or 022.307 or consent of instructor Will be offered IMED Fall Term: MICROSCOPY, OPTICS, IMAGING AND ANALYSIS IN HEALTH Coordinator: 7300 RESEARCH Dr. S. Mai 3 CREDIT HRS Intensive training course/workshop. Offered once per year (See Training # 13461 Overview). Training through lectures, bench work and hands-on experience Will be offered at different imaging workstations. Discussions about appropriate sample preparations, analysis and image acquisition. Critical interpretation of data, and discussion of research applications. Multidisciplinary and training. Invited speakers.
  • 4. 4 ADVANCED MOLECULAR IMAGING IMED Spring Term: Coordinator: 7302 Seminar course in which students will learn about innovative methods and Dr. S. Mai 3 CREDIT HRS advanced analyses of molecular imaging in biomedical research including 2-dimentional and 3-dimensional fluorescent in situ hybridization, live-cell Will be offered CRN # NOT imaging, spectral imaging, and multi-colour imaging. Students will AVAILABLE participate in hands-on laboratory exercises, interactive tutorials and journal club FUNCTIONAL GENOMICS AND WHOLE GENOME ANALYSES IMED 7304 Spring Term Coordinator: Seminar course in which students will learn about functional genomics and Dr. S. Mai 3 CREDIT HRS approaches to whole genome analyses using array technologies. Course content will be delivered by local and external experts in the field. Students Will be offered CRN # NOT will participate in hands-on laboratory exercises with micro-array platforms AVAILABLE and computer-based data analyses, interactive tutorials and journal club. *Green highlight – courses offered in 2010-2011 *Yellow highlight – courses not offered in 2010-2011

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