The improvement which training effects in them is greatly in excess of what would be predicated if one did know the characteristics of the type. The life expectancy, however, is far below the average, and the tendency is to the tuberculosis which I believe to be the hereditary origin of the degeneracy.
Apart from the practical bearing of this attempt at the ethnic classification, considerable philosophical interests attaches to it. The tendency in the present day is to reject the opinion that the various races are merely varieties of the human family having, a common origin, and to insist that climatic or other influences are sufficient to account for the different types of man. Here, however, we have examples of retrogression, or at all events, of departure from one type and the assumption of the characteristics of another.
They have considerable power of imitation, even bordering on being mimics. They are humorous, and a lively sense of the ridiculous often colour their mimicry. This faculty of imitation may be cultivated to a very great extent, and a practical direction given to the results obtained. They are usually able to speak; the speech is thick and indistinct, but may be improved very greatly by a well-directed scheme of tongue gymnastics. The coordinating faculty is abnormal, but not so defective that it cannot be greatly strengthened. By systematic training, considerable manipulative power may be obtained.
Down's essay originally appeared in England in 1866. It is generally credited as the earliest clinical description of what he called "mongoloid idiocy," as a condition separate and distinct from cretinism. The version reprinted here is actually itself a reprint of that original essay,which appeared in The Journal of Mental Science in 1867, and was reprinted in Mental Retardation in February 1995. Down elaborated his views at much greater length in a later book entitled Mental Affections of Children and Youth (1887). The racially based terms 'mongoloid' and 'mongolism' that Down coined continued to be widely used well into the 1980s.
Over 500 Down syndrome individuals in Alabama with no known options for healthcare once they leave pediatric care. Estimate based on a survey of pediatricians and population estimates. Probably over 1000 considering all of Alabama and bordering states.
Provide both primary and referral care for these individuals in one location.
Aims to apply evidence gained from the scientific method to certain parts of medical practice. It seeks to assess the quality of evidence relevant to the risks and benefits of treatments (including lack of treatment).
According to the Centre for Evidence-Based Medicine: "Evidence-based medicine is the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients." [
EBM recognizes that many aspects of medical care depend on individual factors such as quality and value-of-life judgments, which are only partially subject to scientific methods.
EBM, however, seeks to clarify those parts of medical practice that are in principle subject to scientific methods and to apply these methods to ensure the best prediction of outcomes in medical treatment, even as debate about which outcomes are desirable continues.
Health and Well-Being Survey for the Adult Down Syndrome Clinic
This survey asks for your views about the health of the individual with Down syndrome. This information will help keep track of how they feel and how well they are able to do their usual activities. Thank you for completing this survey.
1. In general, would you say the health of the individual is:
Possibility: The presence of gene(s) on chromosome 21 in 3 copies offers protection against atheroma formation.
Thrombin-induced Autoinhibitory Factor, Down Syndrome Critical Region-1, Attenuates NFAT-dependent Vascular Cell Adhesion Molecule-1 Expression and Inflammation in the Endothelium* Takashi Minami, Mai Miura, William C. Aird, and Tatsuhiko Kodama THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 281, NO. 29, pp. 20503–20520, July 21, 2006