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Pharmacology know why, know-what,know-how

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a must read ppt for medical students to know why, what, how about pharmacology....enjoy your reading.... <3 ...satya

a must read ppt for medical students to know why, what, how about pharmacology....enjoy your reading.... <3 ...satya

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Transcript

  • 1. CONGRATULATIONS……..YOU ALL HAVE FAILED
  • 2. YOU ALL HAVE FAILEDTO MISS SUCCESS….!
  • 3. PHARMACOLOGY-KNOW-WHAT, KNOW-WHY, KNOW Dr. V.SATHYA NARAYANAN M.B.B.S., M.D., PROFESSOR OF PHARMACOLOGY
  • 4. PHARMACOLOGY TEXT BOOKS
  • 5. PHARMACOLOGY TEXT BOOKS
  • 6. WHAT IS PHARMACOLOGY ?∗ SCIENCE OF DRUGS AND THEIR∗ INTERACTIONS ON LIVING SYSTEM
  • 7. WHAT IS A DRUG ?∗ ANY SUBSTANCE USEFUL FOR∗ CURING THE DISEASE∗ PREVENTING THE DISEASE
  • 8. WHAT A DRUG ALSO CAN DO ?∗ HARM- From minor to serious∗ Sometimes even FATAL
  • 9. WHAT A DRUG CANNOT DO?∗ Magical cure for every disease…
  • 10. WHY PHARMACOLOGY ?
  • 11. Increased intake of a prescribed and unPrescribed medicine
  • 12. Prescribing drugs is the deciding factor in patient cure
  • 13. To choose drugs wisely
  • 14. WHEN TO STUDY PHARMACOLOGY ?
  • 15. KNOW-WHEN?∗ NOW AND…∗ EVERYDAY∗ WITH BOOKS AND PATIENTS∗ GUIDED BY EXPERTS
  • 16. CONTINUOUS AND EVEN LIFELONG….∗ Should be continuous, life long
  • 17. WHAT TO STUDY INPHARMACOLOGY?
  • 18. WHAT TO STUDY IN PHARMACOLOGY ?∗ General pharmacology - Definitions - Routes of drug administration - Pharmacokinetics - Pharmacodynamics - Adverse drug reactions∗ Systemic pharmacology - ANS, CVS, blood, autacoids related drugs, RS, CNS, GIT, Hormones, Chemotherapy
  • 19. General pharmacological principles∗
  • 20. Definitions
  • 21. Routes of drug administration
  • 22. PHARMACOKINETICS∗ What the body does to the drug.
  • 23. PharmacokineticsIs what the body does to the drug.∗ Absorption∗ Distribution∗ Metabolism∗ Elimination
  • 24. PHARMACODYNAMICS∗ What the drug does to the body.∗
  • 25. PharmacodynamicsIs what the drug does to the body. Interaction of drugs with cellular proteins, such as receptors or enzymes, to control changes in physiological function of particular organs.∗ Drug-Receptor Interactions ∗ Binding∗ Dose-Response ∗ Effect∗ Signal Transduction ∗ Mechanism of action, Pathways
  • 26. Endogenous compounds act on their Receptors Neurotransmitter Neuropeptides Hormones Ionshttp://www.morphonix.com/software/education/science/brain/game/specimens/neurotrans
  • 27. Drug-Receptor Interactions∗Drug-receptor interactions  signals to trigger a cascade ofevents. collection of many cellular responses serve to amplifythe signal produce a final effect.∗Effectors are thus the molecules that translate the drug-receptor interaction into changes in cellular activity.•  •+         EFFECTDRUG UG + RECEPTOR DRUG + RECEPTOR EFFECTOR EFFECTOR INTERACTION COMPLEX SYSTEMSTIMULUS BINDING ACTIVATION TRANSDUCTIONAMPLIFICATION RESPONSE SIGNALLING PATHWAY
  • 28. Adverse drug reactions
  • 29. Prevention is better than cure
  • 30. Clinical pharmacology & drug development
  • 31. SYSTEMIC PHARMACOLOGY
  • 32. Systemic pharmacology∗ ANS∗ CVS∗ BLOOD∗ Autacoids∗ RS∗ CNS∗ GIT∗ Hormones∗ Chemotherapy
  • 33. KNOW-HOW
  • 34. HOW TO STUDY PHARMACOLOGY ?∗ Classification∗ Pharmacological actions∗ Mechanism of action∗ Pharmacokinetics∗ Adverse drug reactions∗ Drug interactions∗ Precautions∗ Contraindications∗ Indications (Therapeutic uses)
  • 35. Classification
  • 36. Pharmacological actions
  • 37. Mechanism of action
  • 38. Pharmacokinetics
  • 39. Adverse drug reactions
  • 40. Drug interactions
  • 41. Precautions
  • 42. Contraindications
  • 43. Indications (Therapeutic uses)
  • 44. DO”S∗ Keep correct time∗ Be attentive∗ Hear and listen∗ Take notes∗ Be relaxed∗ Maintain silence
  • 45. DON”Ts∗ Talk with others during lecture∗ Use cellphones∗ Call the names of your friends
  • 46. Even thousands of miles of journeystarts with a single step…….. lao tzu a chinese mystic
  • 47. A JOKE TO END∗ A chief doctor was on a practical demonstration of the two top most qualities of a skilful doctor to newly arrived young medical students with a patient∗ He said, “listen my dear students…∗ you must have keen observation and tolerance for becoming skilful and efficient”
  • 48. ∗ Then He did a PerRectal examination in the patient and sucked his middle finger∗ The students were amazed and stunned..!∗ He asked “Now can any of you demonstrate this..?”∗ There was a murmuring among the youngsters and slowly One student came forward with bravery
  • 49. ∗ He did the P.R examination through his middle finger and sucked his middle finger with a disgusting face∗ The senior doctor smiled to the student and said , good.. You have tolerance, but no observation and added I did P.R with my index finger and I sucked my middle finger……..

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