Ebola
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Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying ...

Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying to make a difference in the research and development of Ebola virus disease

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Ebola Presentation Transcript

  • 1. Herbal cure for Ebola virus disease (EVD) Presented by Dr. Sudhakar Kokate Director PPRC, India
  • 2. Dedicated to Ebola affected patients all over the world PPRC/INDIA 01
  • 3. What is Virus?  A small infectious agent that replicates only inside the living cells of other organisms  Infect all types of living forms  Also known as Virions  Of different shapes, size 1/100th of average bacterium PPRC/INDIA 02
  • 4. What is Virus?  They are made up of: 1. DNA/RNA, long molecules carrying genetic information 2. Protein 3. An envelope of lipids PPRC/INDIA 03
  • 5. Important viral diseases PPRC/INDIA 04 Influenza Small pox Hepatitis Hepatic cirrhosis Kaposi sarcoma AIDS Measles Pneumonia Bronchitis Common cold Rabies Chickenpox Herpes zoster EVD Viral meningitis
  • 6. Ebola virus (EBOV)  Most dangerous of the known viruses  Named as Ebola in earlier Zaire (2010)  Family – Filoviridae  Species – Zaire ebolavirus PPRC/INDIA 05
  • 7. Ebola virus disease (EVD)  Severe disease, fatality rate upto 90%  Primarily in villages of Central-West Africa  Human to human transmission  First appeared in 1976 in Nizara, Sudan and Yambuku PPRC/INDIA 06
  • 8. Symptoms of EVD  Sudden onset of fever  Intense weakness  Muscle pain  Headache  Sore throat PPRC/INDIA 07
  • 9. Symptoms of EVD  Impaired liver and kidney function  Internal and external bleeding in some cases  Vomiting  Diarrhoea  Rash PPRC/INDIA 08
  • 10. Facts of Ebola  Formerly known as Ebola haemorrhagic fever  Ebola is caused by an RNA virus  Incubation period 2 -21 days  Bleeding is common in later stages PPRC/INDIA 09
  • 11. Types of tests  Antibody: capture enzyme linked immunosorbent assay (ELISA)  Antigen detection tests  Serum neutralization tests PPRC/INDIA 10
  • 12. Types of tests  Reverse transcriptase polymerase chain reaction (RT-PCR) assay  Electron microscopy  Virus isolation by cell culture PPRC/INDIA 11
  • 13. Ebola virus disease outbreak PPRC/INDIA 12 Year Country Cases Deaths % case fatality 1976 Congo 318 280 88 1976 Sudan 284 151 53 1977 Congo 1 1 100
  • 14. Ebola virus disease outbreak PPRC/INDIA 13 1979 Sudan 34 22 69 1994 Gabon - Zaire 52 31 60 1995 Congo - Zaire 315 254 81 1996 Gabon - Zaire 31 21 68
  • 15. Ebola virus disease outbreak PPRC/INDIA 14 2000 Uganda Sudan 425 224 53 2001-2 Gabon - Zaire 65 53 82 2003 Congo - Zaire 202 172 82.2 2005 Congo - Zaire 12 10 83
  • 16. Ebola virus disease outbreak PPRC/INDIA 15 2007 Congo - Zaire 264 187 71 2008 Congo - Zaire 32 14 44 2012 Uganda Sudan 24 17 71 2012 Congo - Zaire 57 29 51
  • 17. Types of tests  Reverse transcriptase polymerase chain reaction (RT-PCR) assay  Electron microscopy  Virus isolation by cell culture PPRC/INDIA 16
  • 18. WHO report There is no cure for Ebola Virus Disease (EVD)  No licensed vaccine  No specific treatment available PPRC/INDIA 17
  • 19. Research work  All over the world  Many scientists, research groups are engaged in R&D about development of drugs, vaccines against Ebola and other diseases PPRC/INDIA 18
  • 20. U.S. Defense Dept. spent $140 mn on Ebola virus disease treatment PPRC/INDIA 19
  • 21. National Agency for food, drug & control …. Scientific committee (NAFDAC) claimed in 2013 effective herbs for Ebola virus and others PPRC/INDIA 20
  • 22. Azadirachta indica - Neem PPRC/INDIA 21
  • 23. Allium sativum - Garlic PPRC/INDIA 22
  • 24. Aloe barbadensis – Aloe vera PPRC/INDIA 23
  • 25. Amaranthus yoruba : Green Amaranth PPRC/INDIA 24
  • 26. Carica papaya - Papaya PPRC/INDIA 25
  • 27. Cymbopogum citratus : Lemon grass PPRC/INDIA 26
  • 28. Dioscorea alata – Water yam PPRC/INDIA 27
  • 29. Euphoria hirta – Asthma plant PPRC/INDIA 28
  • 30. Garcinia kola – Bitter kola PPRC/INDIA 29
  • 31. Momordica charantia – Bitter melon PPRC/INDIA 30
  • 32. Psidium guajava - Guava PPRC/INDIA 31
  • 33. Sesamum indicum – Sesame PPRC/INDIA 32
  • 34. Saccharum officinarum - Sugarcane PPRC/INDIA 33
  • 35. Vernonia amygdalina – Bitter leaf PPRC/INDIA 34
  • 36. Zea mays - Maize PPRC/INDIA 35
  • 37. Attention! All Global scientists!! I suggest following two plants for Ebola : Tulsi, Ocimum sanctum Indian curry leaf tree, Murraya koenigii Do reciprocate: director.pprc@gmail.com From, Director, PPRC PPRC/INDIA 36
  • 38. Ocimum sanctum - Tulsi PPRC/INDIA 37
  • 39. Murraya koenigii – Indian curry leaf tree PPRC/INDIA 38
  • 40. Thank You !! “BE WITH US”