Ebola

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Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying to make a difference in the research and development of Ebola virus disease

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  • Great! people should aware of most dangerous virus that spreads in few minutes.
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  • Amazing Dr. Kokate This presentation is very informative and will boost r&d in researchers and pharma industry
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  • Ebola outbreak !! Medicine expected, R&D on the go
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Ebola

  1. 1. Herbal cure for Ebola virus disease (EVD) Presented by Dr. Sudhakar Kokate Director PPRC, India
  2. 2. Dedicated to Ebola affected patients all over the world PPRC/INDIA 01
  3. 3. What is Virus?  A small infectious agent that replicates only inside the living cells of other organisms  Infect all types of living forms  Also known as Virions  Of different shapes, size 1/100th of average bacterium PPRC/INDIA 02
  4. 4. What is Virus?  They are made up of: 1. DNA/RNA, long molecules carrying genetic information 2. Protein 3. An envelope of lipids PPRC/INDIA 03
  5. 5. Important viral diseases PPRC/INDIA 04 Influenza Small pox Hepatitis Hepatic cirrhosis Kaposi sarcoma AIDS Measles Pneumonia Bronchitis Common cold Rabies Chickenpox Herpes zoster EVD Viral meningitis
  6. 6. Ebola virus (EBOV)  Most dangerous of the known viruses  Named as Ebola in earlier Zaire (2010)  Family – Filoviridae  Species – Zaire ebolavirus PPRC/INDIA 05
  7. 7. Ebola virus disease (EVD)  Severe disease, fatality rate upto 90%  Primarily in villages of Central-West Africa  Human to human transmission  First appeared in 1976 in Nizara, Sudan and Yambuku PPRC/INDIA 06
  8. 8. Symptoms of EVD  Sudden onset of fever  Intense weakness  Muscle pain  Headache  Sore throat PPRC/INDIA 07
  9. 9. Symptoms of EVD  Impaired liver and kidney function  Internal and external bleeding in some cases  Vomiting  Diarrhoea  Rash PPRC/INDIA 08
  10. 10. Facts of Ebola  Formerly known as Ebola haemorrhagic fever  Ebola is caused by an RNA virus  Incubation period 2 -21 days  Bleeding is common in later stages PPRC/INDIA 09
  11. 11. Types of tests  Antibody: capture enzyme linked immunosorbent assay (ELISA)  Antigen detection tests  Serum neutralization tests PPRC/INDIA 10
  12. 12. Types of tests  Reverse transcriptase polymerase chain reaction (RT-PCR) assay  Electron microscopy  Virus isolation by cell culture PPRC/INDIA 11
  13. 13. Ebola virus disease outbreak PPRC/INDIA 12 Year Country Cases Deaths % case fatality 1976 Congo 318 280 88 1976 Sudan 284 151 53 1977 Congo 1 1 100
  14. 14. Ebola virus disease outbreak PPRC/INDIA 13 1979 Sudan 34 22 69 1994 Gabon - Zaire 52 31 60 1995 Congo - Zaire 315 254 81 1996 Gabon - Zaire 31 21 68
  15. 15. Ebola virus disease outbreak PPRC/INDIA 14 2000 Uganda Sudan 425 224 53 2001-2 Gabon - Zaire 65 53 82 2003 Congo - Zaire 202 172 82.2 2005 Congo - Zaire 12 10 83
  16. 16. Ebola virus disease outbreak PPRC/INDIA 15 2007 Congo - Zaire 264 187 71 2008 Congo - Zaire 32 14 44 2012 Uganda Sudan 24 17 71 2012 Congo - Zaire 57 29 51
  17. 17. Types of tests  Reverse transcriptase polymerase chain reaction (RT-PCR) assay  Electron microscopy  Virus isolation by cell culture PPRC/INDIA 16
  18. 18. WHO report There is no cure for Ebola Virus Disease (EVD)  No licensed vaccine  No specific treatment available PPRC/INDIA 17
  19. 19. Research work  All over the world  Many scientists, research groups are engaged in R&D about development of drugs, vaccines against Ebola and other diseases PPRC/INDIA 18
  20. 20. U.S. Defense Dept. spent $140 mn on Ebola virus disease treatment PPRC/INDIA 19
  21. 21. National Agency for food, drug & control …. Scientific committee (NAFDAC) claimed in 2013 effective herbs for Ebola virus and others PPRC/INDIA 20
  22. 22. Azadirachta indica - Neem PPRC/INDIA 21
  23. 23. Allium sativum - Garlic PPRC/INDIA 22
  24. 24. Aloe barbadensis – Aloe vera PPRC/INDIA 23
  25. 25. Amaranthus yoruba : Green Amaranth PPRC/INDIA 24
  26. 26. Carica papaya - Papaya PPRC/INDIA 25
  27. 27. Cymbopogum citratus : Lemon grass PPRC/INDIA 26
  28. 28. Dioscorea alata – Water yam PPRC/INDIA 27
  29. 29. Euphoria hirta – Asthma plant PPRC/INDIA 28
  30. 30. Garcinia kola – Bitter kola PPRC/INDIA 29
  31. 31. Momordica charantia – Bitter melon PPRC/INDIA 30
  32. 32. Psidium guajava - Guava PPRC/INDIA 31
  33. 33. Sesamum indicum – Sesame PPRC/INDIA 32
  34. 34. Saccharum officinarum - Sugarcane PPRC/INDIA 33
  35. 35. Vernonia amygdalina – Bitter leaf PPRC/INDIA 34
  36. 36. Zea mays - Maize PPRC/INDIA 35
  37. 37. Attention! All Global scientists!! I suggest following two plants for Ebola : Tulsi, Ocimum sanctum Indian curry leaf tree, Murraya koenigii Do reciprocate: director.pprc@gmail.com From, Director, PPRC PPRC/INDIA 36
  38. 38. Ocimum sanctum - Tulsi PPRC/INDIA 37
  39. 39. Murraya koenigii – Indian curry leaf tree PPRC/INDIA 38
  40. 40. Thank You !! “BE WITH US”

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