Circadian rhythms

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Circadian rhythms also known as "The Body Clock" is the physical, mental and behavioral changes that follow roughly 24 hrs. cycle responding to light and darkness in the organism.

Circadian rhythms also known as "The Body Clock" is the physical, mental and behavioral changes that follow roughly 24 hrs. cycle responding to light and darkness in the organism.

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  • 1. Circadian rhythms & Human health Presented by Dr. Sudhakar Kokate Director PPRC, India
  • 2. Circadian rhythms .…  Also known as the “Body clock”  Physical, mental and behavioural changes that follow a roughly 24 hrs. cycle responding to light and darkness in the organism  Found in living things, plants, animals and even among tiny microbes PPRC/INDIA 01
  • 3. Circadian rhythms .… PPRC/INDIA 02
  • 4. Circadian rhythms ….  Related to biological cycle  Study of Circadian rhythms and health is known as “Chronobiology”  Biological cycle controls Circadian rhythms – governing of interacting molecules in cells throughout the body PPRC/INDIA 03
  • 5. Master clock ….  Master clock: Brain  A group of nerve cells ‘Suprachiasmatic nucleus’ (SCN) containing 20,000 nerve cells are located in hypothalamus  Location: above optic nerves from eyes cross PPRC/INDIA 04
  • 6. Brain PPRC/INDIA 05
  • 7. Suprachiasmatic nucleus PPRC/INDIA 06
  • 8. About CR ….  Circadian rhythms influence sleep wake cycles, hormone release and other bodily functions  CR – linked to sleep disorders e.g. Insomnia, Obesity, Diabetes, Depression, Bipolar disorders and Seasonal Affective Disorder (SAD) PPRC/INDIA 07
  • 9. Insomnia PPRC/INDIA 08
  • 10. Obesity PPRC/INDIA 09
  • 11. Diabetes PPRC/INDIA 10
  • 12. Depression PPRC/INDIA 11
  • 13. Bipolar disorders PPRC/INDIA 12
  • 14. Seasonal Affective Disorder (SAD) PPRC/INDIA 13
  • 15. About CR ….  CR tells our body when to sleep and regulate many other physiological processes  This internal body clock is affected by environmental cues like sunlight and temperature  When CR is disrupted, sleeping & eating patterns can run amok PPRC/INDIA 14
  • 16. Physiological disruption leads to …. PPRC/INDIA 15
  • 17. Research ….  A growing body of research is examining the adverse health effects like increasing cardio- vascular events, observing neurological problems like depression and bipolar disorders.  It also affects immune and metabolic systems PPRC/INDIA 16
  • 18. Immune system PPRC/INDIA 17
  • 19. Metabolic system PPRC/INDIA 18
  • 20. Research ….  Scientists are looking into: 1. How brain-neuro system works in disorder? 2. What are effective remedies without side effects with minimum duration of time span? 3. Behaviour of Human being in disrupted CR position PPRC/INDIA 19
  • 21. Research …. 4. Treatment of sleep disorders, Jet lag and other health related issues 5. Do Ayurvedic plants control Circadian rhythms in plants, animals and microbes? If so how and at what level of output? PPRC/INDIA 20
  • 22. Research …. 6. Are there any natural control for strengthening nerves and muscle? If so how and what mechanism does it possess? PPRC/INDIA 21
  • 23. Remedies ….  Change or modify lifestyle  Ideal diet plan – implementation  Yoga, exercises and meditation  Use of herbal technology  Well disciplinary actions in exact time  Strengthen and calm – nerves and muscles PPRC/INDIA 22
  • 24. Yoga PPRC/INDIA 23
  • 25. Exercise PPRC/INDIA 24
  • 26. Meditation PPRC/INDIA 25
  • 27. Cryobiology  Study of cell preservation technology with low temperature  Applied science  Rule: Every 10°C reduction in temperature = 50 % decrease in oxygen consumption PPRC/INDIA 26
  • 28. Cryobiology  Temperature ranges 32 to 37°C and -80 to -196°C  Many Journals, Societies study Cryobiology PPRC/INDIA 27
  • 29. Neurochemicals …. Organic molecules participating in Neural activity  Neuropeptide: Oxytocin signifies maternal behaviour, stress wound healing  Glutamate  GABA: Inhibits neurotransmission PPRC/INDIA 28
  • 30. Neurochemicals PPRC/INDIA 29
  • 31. Neuropeptide PPRC/INDIA 30
  • 32. Oxytocin PPRC/INDIA 31
  • 33. Glutamate PPRC/INDIA 32
  • 34. GABA PPRC/INDIA 33
  • 35. Neurochemicals …. Organic molecules participating in Neural activity  Dopamine: Function of the limbic system, emotional function and control  Serotonin: Mood, sleep and alertness, sensation of pleasure PPRC/INDIA 34
  • 36. Dopamine PPRC/INDIA 35
  • 37. Serotonin PPRC/INDIA 36
  • 38. Neurochemicals …. Organic molecules participating in Neural activity  Acetylcholine: Memory  Nitric oxide  Endocannabinoids: Eicosanoids PPRC/INDIA 37
  • 39. Acetylcholine PPRC/INDIA 38
  • 40. Nitric oxide PPRC/INDIA 39
  • 41. Endocannabinoids PPRC/INDIA 40
  • 42. Foods for healthy nerves …. ₪ Milk ₪ Yogurt ₪ Honey ₪ Apple ₪ Mangoes PPRC/INDIA 41 ₪ Potatoes ₪ Bananas ₪ Herbal tea ₪ Whole grain ₪ Sweet potatoes
  • 43. Foods for healthy nerves …. PPRC/INDIA 42
  • 44. Foods for healthy nerves …. ₪ Pineapples ₪ Beet salad ₪ Grape fruits ₪ Oranges ₪ Almonds PPRC/INDIA 43 ₪ Green salad ₪ Dates ₪ Cashew nuts ₪ Coconut water
  • 45. PPRC/INDIA 44
  • 46. ₪ Tulsi ₪ Sunflower ₪ Papaya ₪ Peppermint PPRC/INDIA 45 ₪ Avocado ₪ Cabbage ₪ Cauliflower ₪ Asparagus
  • 47. Tulsi (Ocimum sanctum) PPRC/INDIA 46
  • 48. Sunflower PPRC/INDIA 47
  • 49. Papaya PPRC/INDIA 48
  • 50. Peppermint PPRC/INDIA 49
  • 51. Avocado PPRC/INDIA 50
  • 52. Cabbage PPRC/INDIA 51
  • 53. Cauliflower PPRC/INDIA 52
  • 54. Asparagus PPRC/INDIA 53
  • 55. ₪ Alfalfa ₪ Parsley ₪ Garlic ₪ Beet PPRC/INDIA 54 ₪ Kale ₪ Hemp ₪ Fenugreek ₪ Lime
  • 56. Alfalfa PPRC/INDIA 55
  • 57. Parsley PPRC/INDIA 56
  • 58. Garlic PPRC/INDIA 57
  • 59. Beet PPRC/INDIA 58
  • 60. Kale PPRC/INDIA 59
  • 61. Hemp PPRC/INDIA 60
  • 62. Fenugreek PPRC/INDIA 61
  • 63. Lime PPRC/INDIA 62
  • 64. Thank You !! “BE WITH US”