Clinical Trails of Marine Natural Products

484 views
356 views

Published on

Pharmacology

Published in: Health & Medicine, Business
0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
484
On SlideShare
0
From Embeds
0
Number of Embeds
50
Actions
Shares
0
Downloads
35
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

Clinical Trails of Marine Natural Products

  1. 1. 5/16/2014
  2. 2. 5/16/2014
  3. 3. Clinical Trial5/16/2014
  4. 4. • Clinical trials are set up in a way to assess the methods and procedures that offers new treatment effectively and safely to patients. • The new treatments must prove to be safe and secure and efficient in scientific studies with a specific amount of patients prior to making the same available to all the patients. 5/16/2014
  5. 5. 5/16/2014
  6. 6.  Involve human subjects.  Move forward in time.  Most have a comparison CONTROL group.  Must have method to measure intervention.  Focus on unknowns: effect of medication. 5/16/2014
  7. 7.  Must be done before medication is part of standard of care.  Test a certain hypothesis.  Study protocol must be built on ethical science.  Control for any potential biases. 5/16/2014
  8. 8. 5/16/2014
  9. 9. 5/16/2014
  10. 10.  In recent years, marine natural product bio-prospecting has yielded a considerable number of drug candidates.  Research into the ecology of marine natural products has shown that many of these compounds function as chemical weapons and have evolved into highly potent inhibitors of physiological processes in the competitors of the marine organisms that use them.  Most of these molecules are still in preclinical or early clinical development but some are already on the market. 5/16/2014
  11. 11.  Some of the natural products isolated from marine invertebrates have been shown to be microbial origin and this is the case for the majority of such molecules.  Marine microorganisms, whose immense genetic and biochemical diversity is only beginning to be appreciated, look likely to become a rich source of novel chemical entities for the discovery of more effective drugs. 5/16/2014
  12. 12. 5/16/2014
  13. 13. 5/16/2014
  14. 14. 5/16/2014
  15. 15. 5/16/2014
  16. 16. 5/16/2014
  17. 17. 5/16/2014
  18. 18. 5/16/2014
  19. 19. 5/16/2014
  20. 20. 5/16/2014
  21. 21. 5/16/2014
  22. 22. 5/16/2014
  23. 23. 5/16/2014
  24. 24. 5/16/2014
  25. 25. 5/16/2014
  26. 26. 5/16/2014
  27. 27. 27
  28. 28. 5/16/2014
  29. 29. 5/16/2014
  30. 30. 5/16/2014
  31. 31. 5/16/2014
  32. 32. 5/16/2014
  33. 33. 5/16/2014
  34. 34. 5/16/2014
  35. 35. 5/16/2014
  36. 36. 5/16/2014
  37. 37. 5/16/2014
  38. 38. 5/16/2014
  39. 39. 5/16/2014
  40. 40. 5/16/2014

×