Mixing Medicine and Marijuana
Scott E Yasko – PRIUM
Rachel Brozina, esq. – Lester, Norton & Brozina
Michael DeGeorge Jr., ...
Quick History of Marijuana in the U.S.
• Cannabis was used legitimately at the turn of
the century
– Primarily used for pa...
The Administration of Marijuana
• Smoke
• Oil extract & Butter
– Added to and used to make foods
• Tinctures & Tonics
– Tr...
Marijuana in the U.S. Today
• According to CBS News, 51% of Americans
support full legalization
• Indicated for diagnoses ...
What’s Next?
• Reassess drug scheduling
– Schedule I indicates no medicinal use
– 1988, DEA ALJ ruled in favor of reclassi...
Federal versus State Law
U.S. Constitution
•Supremacy Clause: generally, federal law
supersedes state law in areas in whic...
Federal versus State Law
Controlled Substances Act
•Purpose: regulate the manufacture,
importation, possession, use, and
d...
USDOJ Memo to U.S. Attorneys
August 29, 2013
• Urges U.S. Attorneys to exercise their discretion in
using federal resource...
21 Jurisdictions Have Legalized
Medical Marijuana
• Alaska
• Arizona
• California
• Colorado*
• Connecticut
• DC
• Delawar...
Image from Isaac Reese via reason.com
Pediatric Exposure to Marijuana in
Decriminalized States
Adapted by CESAR from Wang, G.S., Roosevelt, G., Le Lait, M-C, Ma...
New Illicit Drug Use- 2012
Substance Abuse and Mental Health Services Administration, Results from the 2012 National
Surve...
New Illicit Drug Use- 2012
13
Substance Abuse and Mental Health Services Administration, Results from the 2012 National
Su...
Marijuana use increasing
Adapted by CESAR from Substance Abuse and Mental Health Services Administration, Results from the...
Perceived risk of marijuana
•University of Michigan, 2013 Monitoring the Future Study
Marijuana and poly drug abuse
58% of primary marijuana admissions reported abuse
of additional substances
Marijuana and Nonadherence
• Retrospective review of 116,011 urine
samples
• Patients prescribed hydrocodone (excluding
pr...
Marijuana and Nonadherence
An analysis of the association between marijauana use and potential nonadherence in patients pr...
An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeo...
An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeo...
Thank You
Scott E Yasko
PRIUM
National Account Executive
(678) 735-7315
syasko@prium.net
Rachel Brozina, esq.
Lester, Nort...
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Tuesday Vision Session: Ameritox: Mixing Medicine and Marijuana

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Tue vs ameritox -yasko-brasika_de_george

  1. 1. Mixing Medicine and Marijuana Scott E Yasko – PRIUM Rachel Brozina, esq. – Lester, Norton & Brozina Michael DeGeorge Jr., PharmD – Ameritox Rx Drug Abuse Summit – April 22, 2014 – Atlanta, GA
  2. 2. Quick History of Marijuana in the U.S. • Cannabis was used legitimately at the turn of the century – Primarily used for pain – Use declined with negative public perception and the development of aspirin and morphine • 1925, League of Nations sign a treaty restricting use to scientific and medical • Became illegal in 1937 via the Marijuana Tax Act
  3. 3. The Administration of Marijuana • Smoke • Oil extract & Butter – Added to and used to make foods • Tinctures & Tonics – Transdermal, sublingual and ingested • Vaporized – Heating the plant to inhale the mist – Alternative to smoking
  4. 4. Marijuana in the U.S. Today • According to CBS News, 51% of Americans support full legalization • Indicated for diagnoses such as chronic and cancer pain, seizure disorders, etc. – Varies by state – Physicians do not prescribe; they recommend • Medical Marijuana has potential – Charlotte Figi – Dravet Syndrome – Chaz Moore – myoclonus diaphragmatic flutter
  5. 5. What’s Next? • Reassess drug scheduling – Schedule I indicates no medicinal use – 1988, DEA ALJ ruled in favor of reclassification • More robust studies are needed – Red tape surrounding U.S. studies – Leading research coming out of Israel and Spain
  6. 6. Federal versus State Law U.S. Constitution •Supremacy Clause: generally, federal law supersedes state law in areas in which Congress has appropriately exercised its power to legislate •Commerce Clause: generally, Congress has express power to regulate commerce among the states
  7. 7. Federal versus State Law Controlled Substances Act •Purpose: regulate the manufacture, importation, possession, use, and distribution of certain substances •Execution: five schedules outline the qualifications for a substance to be classified • Schedule 1 substances: 1. High potential for abuse, 2. No currently accepted medical use in treatment in US, and 3. No accepted safety for use of the substance under medical supervision. • Prescription cannot be written for substance U.S. Supreme Court decision: Gonzales v. Raich •Situation: a caregiver and a patient possessing and using marijuana per California’s Compassionate Use Act sought an injunction to stop government from interfering with their activities •Plaintiffs’ argument: CSA is unconstitutional as applied to their conduct •Government’s argument: CSA preempts state law; Congress may regulate and prohibit use and possession of marijuana under Commerce Clause •Decision: Congress has authority to prohibit possession and use of marijuana, even for medical purposes, under commerce clause. •Rationale: marijuana grown for personal consumption is likely to create high demand in the interstate market; this diversion into the interstate market interferes with federal government’s interest in eliminating commercial transactions.
  8. 8. USDOJ Memo to U.S. Attorneys August 29, 2013 • Urges U.S. Attorneys to exercise their discretion in using federal resources to prosecute individuals using marijuana for medical purposes • Emphasizes federal policy of enforcing CSA to prevent: 1. distribution of marijuana to minors 2. revenue falling into hands of dangerous drug cartels 3. diverting medical marijuana from legal states to other states 4. state-authorized marijuana activity from being used as a cover for trafficking other illegal drugs 5. violence in the cultivation and distribution of marijuana 6. drugged driving and other adverse public health consequences 7. growing marijuana on public or federal lands
  9. 9. 21 Jurisdictions Have Legalized Medical Marijuana • Alaska • Arizona • California • Colorado* • Connecticut • DC • Delaware • Hawaii • Illinois • Maine • Michigan • Montana • Nevada • New Hampshire • New Jersey • New Mexico • Oregon • Rhode Island • Vermont • Washington* * Allows for recreational use
  10. 10. Image from Isaac Reese via reason.com
  11. 11. Pediatric Exposure to Marijuana in Decriminalized States Adapted by CESAR from Wang, G.S., Roosevelt, G., Le Lait, M-C, Martinez, E.M., Bucher-Bartelson, B., Bronstein, A.C., and Heard, K., “Association of Unintentional Pediatric Exposures with Decriminalization of Marijuana in the United States,” Annals of Emergency Medicine, In Press, 2014. For more information, please contact Dr. George Wang at george.wang@childrenscolorado.org.
  12. 12. New Illicit Drug Use- 2012 Substance Abuse and Mental Health Services Administration, Results from the 2012 National Survey on Drug Use and Health: Summary of National Findings, NSDUH Series H-46, HHS Publication No. (SMA) 13-4795. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2013.
  13. 13. New Illicit Drug Use- 2012 13 Substance Abuse and Mental Health Services Administration, Results from the 2012 National Survey on Drug Use and Health: Summary of National Findings, NSDUH Series H-46, HHS Publication No. (SMA) 13-4795. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2013.
  14. 14. Marijuana use increasing Adapted by CESAR from Substance Abuse and Mental Health Services Administration, Results from the 2012 National Survey on Drug Use and Health: Detailed Tables, 2013. Available online at http://www.samhsa.gov/data/NSDUH/2012SummNatFindDetTables/Index.aspx
  15. 15. Perceived risk of marijuana •University of Michigan, 2013 Monitoring the Future Study
  16. 16. Marijuana and poly drug abuse 58% of primary marijuana admissions reported abuse of additional substances
  17. 17. Marijuana and Nonadherence • Retrospective review of 116,011 urine samples • Patients prescribed hydrocodone (excluding prn) • May 16, 2011 to May 15, 2012 • Broken into three categories for analysis – THC positive as only illicit (n=15,153) – Cocaine positive as only illicit (n=1731) – No illicit detected (n= 99,115) An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeorge M, Dawson E, et al. American Academy of Pain Medicine annual meeting 2013
  18. 18. Marijuana and Nonadherence An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeorge M, Dawson E, et al. American Academy of Pain Medicine annual meeting 2013
  19. 19. An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeorge M, Dawson E, et al. American Academy of Pain Medicine annual meeting 2013 Marijuana and Nonadherence
  20. 20. An analysis of the association between marijauana use and potential nonadherence in patients prescribed hydrocodone. DeGeorge M, Dawson E, et al. American Academy of Pain Medicine annual meeting 2013 Marijuana and Nonadherence
  21. 21. Thank You Scott E Yasko PRIUM National Account Executive (678) 735-7315 syasko@prium.net Rachel Brozina, esq. Lester, Norton & Brozina, p.c. rachel@lesternortonlaw.com Michael DeGeorge, PharmD Ameritox Associate Director, Medical Affairs michael.degeorge@ameritox.com

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