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Liver Injury linked to Flavocoxid
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Liver Injury linked to Flavocoxid

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Flavocoxid, a natural solution used to cure arthritis, may have been responsible for serious liver injury in four patients doing research of drug-induced liver injury, according to the discoveries of ...

Flavocoxid, a natural solution used to cure arthritis, may have been responsible for serious liver injury in four patients doing research of drug-induced liver injury, according to the discoveries of US research.

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Liver Injury linked to Flavocoxid Presentation Transcript

  • 1.  The liver supports almost every organ in thevertebrates and some other animals, is vital forsurvival. Because of its strategic location andmultidimensional functions, the liver is alsoprone to many diseases. Flavocoxid, a natural solution used to curearthritis, may have been responsible for seriousliver injury in four patients doing research ofdrug-induced liver injury, according to thediscoveries of US research. Flavocoxids are categorized as a ‘medical food’in the US and can only be obtained onprescription. Manufacturers of healthcarefoods do not have to seek approval for theirproducts with the US Food
  • 2. Symptoms and signs of liver injury: Jaundice Pruritus Stomach pain Marked elevations inalanine aminotransferase
  • 3. Symptoms appeared within 1-3 months of starting flavocoxids andcaused moderate liver injury in three patients and mild injury inone. “Each patient’s liver injury began to resolve within a few daysafter stopping flavocoxid”, written by the authors.
  • 4. Conclusion :Liver biochemistry values decreased to the normal rangewithin 3 to 12 weeks after flavocoxid was stopped, and allpatients recovered without suffering from acute liverfailure. Causality was adjudicated as highly likely in 3patients and as possible in 1 patient. The frequency andmechanism of liver injury could not be assessed.Flavocoxid can cause clinically significant liver injury,which seems to resolve within weeks after cessation.