Liver Injury linked to Flavocoxid

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Flavocoxid, a natural solution used to cure arthritis, may have been responsible for serious liver injury in four patients doing research of drug-induced liver injury, according to the discoveries of US research.

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Liver Injury linked to Flavocoxid

  1. 1.  The liver supports almost every organ in thevertebrates and some other animals, is vital forsurvival. Because of its strategic location andmultidimensional functions, the liver is alsoprone to many diseases. Flavocoxid, a natural solution used to curearthritis, may have been responsible for seriousliver injury in four patients doing research ofdrug-induced liver injury, according to thediscoveries of US research. Flavocoxids are categorized as a ‘medical food’in the US and can only be obtained onprescription. Manufacturers of healthcarefoods do not have to seek approval for theirproducts with the US Food
  2. 2. Symptoms and signs of liver injury: Jaundice Pruritus Stomach pain Marked elevations inalanine aminotransferase
  3. 3. Symptoms appeared within 1-3 months of starting flavocoxids andcaused moderate liver injury in three patients and mild injury inone. “Each patient’s liver injury began to resolve within a few daysafter stopping flavocoxid”, written by the authors.
  4. 4. Conclusion :Liver biochemistry values decreased to the normal rangewithin 3 to 12 weeks after flavocoxid was stopped, and allpatients recovered without suffering from acute liverfailure. Causality was adjudicated as highly likely in 3patients and as possible in 1 patient. The frequency andmechanism of liver injury could not be assessed.Flavocoxid can cause clinically significant liver injury,which seems to resolve within weeks after cessation.

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