NuSoothe Brochure


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I created this 4-page product brochure to serve as a sales tool for NuSoothe™, a compounded transdermal pain cream. The target audience is orthopedic and podiatric surgeons. Imagery is used throughout to give the impression of a fast, full return to an active lifestyle. Text highlights the various NuSoothe formulations, benefits of using the product, and the ways in which the Lipoderm® base makes NuSoothe uniquely effective. The back page briefly describes the company's value proposition and the other therapies in its "Continuum of Care".

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NuSoothe Brochure

  1. 1. Personalized Solutions for Pain Management Distributed by
  2. 2. Benefits of the NuSoothe Series Faster, More Complete Relief Uses the only base proven to bring 4 drugs simultaneously through the skin for faster, more effective pain management. Faster Return to Daily Living May reduce the need for oral pain medications that affect the entire body. This puts patients back on their feet faster, completing daily activities sooner (like driving). Prolonged Patient Relief Anesthetic bupivacaine lasts longer than the more commonly used tetracaine and lidocaine. 1 Fewer Side Effects Avoids the side effects of oral pain medications, like digestive issues, drowsiness, loss of driving ability, addiction and overdose. Safer And Avoids Patient Error Tube dispenses the appropriate, premeasured amount of cream for a single dose. Can be used up to 5 times per day. Tube contains UV protection to prevent chemical breakdown. NuSoothe Series The NuSoothe series consists of three transdermal creams formulated in a Lipoderm® base that drives multiple drugs simultaneously through the skin. NuSoothe achieves faster drug delivery and better absorption for improved pain relief. plantar fasciitis NuSoothe PF is designed to alleviate pain caused by plantar fasciitis and other inflammatory conditions of the foot. The drug combination helps loosen the tight bundle of fascia at or near the site of the patient’s pain. NuSoothe™ PF Flurbiprofen Gabapentin Diphenhydramine Cyclobenzaprine Bupivacaine 10% 6% 5% 2% 1% pain, inflammation & muscle spasms The original NuSoothe formulation treats pain, inflammation and muscle spasms locally. It contains four drugs with different mechanisms of action to quickly and effectively alleviate discomfort. NuSoothe™ Flurbiprofen Gabapentin Cyclobenzaprine Bupivacaine 10% 6% 2% 1% 30% neuropathic pain NuSoothe Plus is used to treat neuropathic pain, such as that caused by diabetic neuropathy. It can be prescribed in addition to NuSoothe and NuSoothe PF to help with difficult-to-treat nerve pain. NuSoothe™ Plus Ketamine
  3. 3. Breakthrough Studies of Lipoderm® The First Transdermal Base to Undergo Rigorous Testing According to the latest competitive studies, NuSoothe’s Lipoderm transdermal base delivers ketoprofen (NSAID) more quickly and with better absorption. In addition, Lipoderm is the only base proven to bring 4 drugs simultaneously through the skin. This means faster relief and the potential for better outcomes. Delivers Ketoprofen Better and Faster Percutaneous Absorption Flux Profile of Ketoprofen Mean from 3 Donors as µg/cm2 /hr • This formulation delivered ketoprofen more rapidly than all other formulations. Flux(µg/cm2 /hr) Mid Time (hr) Competitor Lipoderm® 14.5% Lipoderm® 5.5% PLO • Percent of ketoprofen dose delivered completely through human skin in vitro was significantly better with Lipoderm versus PLO. Percent Permeation of Ketoprofen Through Human Skin and Into Receptor Solution Using human skin in vitro Only Base Proven to Deliver 4 Drugs Simultaneously Percent Permeation of Multiple Drugs Beyond Stratum Corneum Through ex vivo human skin • Lipoderm delivered ketamine HCl, gabapentin, clonidine HCl and baclofen simultaneously and intact. • Drugs were selected due to their frequent use in topical pain formulations. Ketamine Clonidine Baclofen Gabapentin 4% 4% 45% 21%
  4. 4. NuPulse® Provides iceless cold compression, DVT prophylaxis and thermal contrast therapy to ease pain, reduce swelling and speed healing. iCPM™ “Smart” continuous passive motion improves range of motion for knees, shoulders, hips, elbows and more. Our Continuum of Care NuLife Med’s Continuum of Care consists of a range of cutting-edge, robust therapies that work together to improve patient outcomes after surgery or injury. All therapies are provided with in-home, concierge service, 7 days per week, with no unexpected cost to the patient. WARNING: If patient is allergic to any of the ingredients in NuSoothe™, patient should not use the medication. Patient should contact the pharmacy/physician immediately. SIDE EFFECTS: If allergic, patients may respond negatively to any of the medications represented in this therapy. Although absorption of an appreciable amount of the active ingredients is uncommon, some can occur in rare situations. Absorption, if it does occur, will typically result in stomach upset (anti-inflammatory) and drowsiness (muscle relaxant, nerve pain suppressant or anesthetics). If patient experiences any of these side effects (or other events that they feel are abnormal), patient should contact clinical staff. OVERDOSE: If an overdose is identified, please contact the pharmacy toll-free at 800-850- 2101. Poison control can also be reached at 1-800-222-1222. MISSED DOSE: The patient may apply a missed dose as soon as he/she recognizes that is has been missed. Please allow a minimum of 4 hours between applications unless otherwise directed by a healthcare professional. STORAGE: Store this medication in a cool, dry place. Avoid exposure to excessive heat, sunlight or dampness. 250 North Commercial Street, Suite 3003, Manchester, NH 03101 • 1. Annals of Emergency Medicine. 1987, 16(7); 752-757 NuSoothe™ Transdermal analgesic cream treats pain, swelling and muscle spasms locally without the side effects of oral medications. Bone Growth Stimulator 30-minute daily treatment with combined magnetic fields helps heal persistent fractures and non-unions. Additional Therapies NuLife Med also offers transcutaneous electrical nerve stimulation (TENS), muscle stimulation and select immobilizing braces.