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Nargess Tavakoli
 

Nargess Tavakoli

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alopecia areata

alopecia areata

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    Nargess Tavakoli Nargess Tavakoli Presentation Transcript

    • Alopecia Areata Nargess Tavakoli Guilan university of medical sciences
      • A nonscarring type of alopecia
      • Many different patterns
      • The true cause ?
    • History
      • Acute onset
      • can affect any hair-bearing area
      • scalp
      • Sigle/multiple
      • Itch?
    • Physical Exam
      • Alopecia pattern in AA?
      • Other findings?
    • Pattern of alopecia
      • Patchy
      • Ophiasis
      • sisaipho (ophiasis spelled backwards)
      • diffuse
    •  
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    • Ophiasis
    •  
    • Alopecia Totalis
    • AT
    • Alopecia universalis
      • complete loss of hair on all hair-bearing areas
      • Rare
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    • Nail involvement
      • Pitting
      • Several other abnormalities have been reported
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    • Epidemiology
      • Prevalence : 0.1-0.2% in the general population
      • Sex: F = M
      • Age: can occur at any age / more common before 40yo,esp. childhood & adolescence
    • physiopathology
      • AA progresses as a wave of follicles which enter telogen prematurely
      • Autoimmune/T_cell mediated/genetic
    • Etiology
      • The true cause: unknown
      • autoimmune?
      • Genetic?
      • Infection?
      • Emotional stress?
    • Evidence supports the autoimmune hypothesis
      • Other autoimmune disease
      • Changes in Immune system
      • (cellular/homoral)
      • Experiments on mice
    • Genetic
      • Familial? 4_27%
      • AD?
      • HLA
      • Atopia
      • Down’s synd.
      • Infection? CMV?
      • Emotional stress?
    •  
    • Diagnosis
      • Clinicaly
      • Biopsy?
      • Thyroid tests?
      • Chronic
      • Regrowth(+/- therapy)
      •  usually
      • How much does it take?
      • Recurrence may occur
      Prognosis
    • White hair regrowth in alopecia areata.
    • Adverse prognosis factors
      • onset at a young age
      • severe forms
      • + FH of AA
      • nail dystrophy
      • Ophiasis
    • Treatment
    • Treatment
      • No medication?
      • Local steroids  atrophy
      • Antralen
      • Systemic steroids
      • Irritant dermatitis
      • False hair to cover?
    •