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PillboxPharmaceutical Imaging, Identification, and Reference<br />http://pillbox.nlm.nih.gov<br />National Library of Medi...
Overview<br /><ul><li>Connecting high-quality images of solid-dosage forms with the SPL (SPLIMAGE)
Initiating a pilot project to create a library of images of Rx, solid-dosage forms (U.S. market)
Creating a system for comparative review/rapid identification</li></li></ul><li>Origins<br /><ul><li>National Library of M...
Center for Drug Evaluation and Research/FDA
Poison Control Centers
Department of Veterans Affairs</li></li></ul><li>NLM/FDA<br />Reference/PatientSafetyInitiative<br /><ul><li>Working with ...
Set standards for consistent high-quality images
Hosting images at NLM
SPL already being hosted through DailyMed
Prototype images shot at VA CMOP
Pilot project (Fall 2009)
Public domain resource
Scalable/portable framework</li></li></ul><li>Acquisition    AnalysisApplication<br />FDA Structured Product Label (SPL)<b...
Pillbox lookup table v1<br />
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Pillbox at US Pharmacopeia's Annual Scientific Meeting

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presentation of NLM/FDA patient-safety initiative Pillbox at U.S. Pharmacopeia's Annual Scientific Meeting, September 22, 2009.

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  • Pillbox http://pillbox.nlm.nih.gov is currently in closed beta. Contact pillbox@mail.nih.gov if interested in participating.
  • Pillbox http://pillbox.nlm.nih.gov is currently in closed beta. Contact pillbox@mail.nih.gov if interested in participating.
  • http://dailymed.nlm.nih.gov
  • http://druginfo.nlm.nih.gov
  • Transcript of "Pillbox at US Pharmacopeia's Annual Scientific Meeting"

    1. 1. PillboxPharmaceutical Imaging, Identification, and Reference<br />http://pillbox.nlm.nih.gov<br />National Library of Medicine<br />National Institutes of Health<br />U.S. Dept. of Health and Human Services<br />David Hale, Project Manager<br />david.hale@nih.gov<br />301.496.3042<br />
    2. 2. Overview<br /><ul><li>Connecting high-quality images of solid-dosage forms with the SPL (SPLIMAGE)
    3. 3. Initiating a pilot project to create a library of images of Rx, solid-dosage forms (U.S. market)
    4. 4. Creating a system for comparative review/rapid identification</li></li></ul><li>Origins<br /><ul><li>National Library of Medicine/NIH
    5. 5. Center for Drug Evaluation and Research/FDA
    6. 6. Poison Control Centers
    7. 7. Department of Veterans Affairs</li></li></ul><li>NLM/FDA<br />Reference/PatientSafetyInitiative<br /><ul><li>Working with imaging experts
    8. 8. Set standards for consistent high-quality images
    9. 9. Hosting images at NLM
    10. 10. SPL already being hosted through DailyMed
    11. 11. Prototype images shot at VA CMOP
    12. 12. Pilot project (Fall 2009)
    13. 13. Public domain resource
    14. 14. Scalable/portable framework</li></li></ul><li>Acquisition AnalysisApplication<br />FDA Structured Product Label (SPL)<br />SPLCOLOR<br />SPLIMPRINT<br />SPLSHAPE<br />SPLSIZE<br />SPLSCORE<br />DEA_SCHEDULE<br />INGREDIENTS<br />EXCIPIENTS<br />SPONSOR<br />SETID, NDC…<br />RxNorm<br />Standardized ingredient listing<br />Product Code<br />NDC9<br />RXCUI<br />RXTTY<br />RXSTRING<br />Rapid Identification of Unknowns<br />Information Provision<br />Drug Information Portal<br />DailyMed<br />PubMed<br />MedlinePlus<br />NLM-generated metadata<br />User Interface design<br />Search experience<br />Relevancy ranking<br />Fuzzy logic<br />NLM Image Acquisition and Analysis<br />Segmentation<br />Frame registration<br />Sub-mm measurements<br />LAB color space<br />K-means clustering<br />
    15. 15. Pillbox lookup table v1<br />
    16. 16.
    17. 17.
    18. 18.
    19. 19.
    20. 20.
    21. 21.
    22. 22.
    23. 23.
    24. 24.
    25. 25. Dialogue with Manufacturers<br /><ul><li>Sponsor submission of images to SPL for reference and enhancing patient safety
    26. 26. Logistics/sustainability
    27. 27. Acquiring samples and imaging
    28. 28. Manufacturers verifying images and submitting image for inclusion with SPL
    29. 29. Incorporate digital imaging currently performed by sponsors
    30. 30. Enhance accuracy of SPL</li></li></ul><li>Pilot Project (Fall 2009)<br /><ul><li>NLM imaging at FDA facility, Rockville, MD
    31. 31. FDA call for voluntary submission of samples
    32. 32. 6 samples of each solid dosage form
    33. 33. NLM will provide SPL-ready images AND master high-resolution images
    34. 34. Sponsor submission of SPLIMAGE
    35. 35. HHS/ASPR disposal of samples</li></li></ul><li>Pillbox<br />http://pillbox.nlm.nih.gov<br />David Hale, Project Manager<br />david.hale@nih.gov<br />301.496.3042<br />National Library of Medicine<br />National Institutes of Health<br />U.S. Department of Health and Human Services<br />
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