The Modern World Epidemic Lyme Disease
<ul><li>Discussed This Lecture </li></ul><ul><li>What is Lyme Disease? </li></ul><ul><li>Symptoms of Lyme </li></ul><ul><l...
What is Lyme Disease? <ul><li>A vector-borne bacterial infection caused by the  borrelia bergdorferi  bacterium, commonly ...
 
 
 
Ixodes Pacificus  Tick  fully engorged
 
Barbed Mouthpiece of Tick
Symptoms of Lyme <ul><li>The Tick Bite  (fewer than 50% recall a tick bite or get/see the rash)  </li></ul><ul><li>Rash at...
<ul><li>Facial paralysis (Bell's Palsy)   </li></ul><ul><li>Tingling of nose, (tip of) tongue, cheek or facial flushing   ...
<ul><li>Ears/Hearing </li></ul><ul><li>Decreased hearing in one or both ears, plugged ears   </li></ul><ul><li>Buzzing in ...
<ul><li>Musculoskeletal System   </li></ul><ul><li>Bone pain, joint pain or swelling, carpal tunnel syndrome   </li></ul><...
<ul><li>Neurologic System   </li></ul><ul><li>Tremors or unexplained shaking   </li></ul><ul><li>Burning or stabbing sensa...
<ul><li>Psychological well-being   </li></ul><ul><li>Mood swings, irritability, bi-polar disorder   </li></ul><ul><li>Unus...
<ul><li>Mental Capability   </li></ul><ul><li>Memory loss (short or long term)   </li></ul><ul><li>Confusion, difficulty i...
<ul><li>General Well-being   </li></ul><ul><li>Unexplained weight gain, loss   </li></ul><ul><li>Extreme fatigue   </li></...
Examples of Erythra Migrans  (Bull’s Eye Rash)
Current Canadian Diagnosis &Testing <ul><li>CLINICAL DIAGNOSIS* </li></ul><ul><ul><ul><li>*Canadian Doctors primarily untr...
Controversy in Testing <ul><li>Negative ELISA in Canada commonly results in positive Western Blot in US labs </li></ul><ul...
Why Testing Fails Canadians <ul><li>ELISA test known to produce  notoriously false  results </li></ul><ul><li>Doctors lack...
Current Canadian Treatment  Protocol <ul><li>30 day antibiotic treatment is  </li></ul><ul><li>currently considered suffic...
Treatment Controversy <ul><li>Many patients still exhibit symptoms after 30 day treatment </li></ul><ul><li>borrelia bergd...
 
Lyme Bacterium  Borrelia bergdorferi  in spirochete formation   Successfully killed by antibiotics in this stage
Cystic Form of  Borrelia bergdorferi , Lyme bacteria Special drug treatment required during this stage
Why Treatment Protocol Must Change <ul><li>Cystic Form not readily accepted by physicians </li></ul><ul><li>High rate of m...
Why Research is Desperately Needed <ul><li>No current or accurate Lyme data exists which considers growth in US directly a...
 
With approximately 20,000 new cases reported each year,  Lyme disease is the most common vector-borne disease in the Unite...
Spread extrapolated by known Growth Rate  2006 to 2007
Geographical Locations of Tick Species
<ul><li>2.   Independent /Gov’t Studies  </li></ul><ul><li>are few & far between  </li></ul><ul><li>and results are not </...
 
Global Warming is Affecting the Spread of Tick Borne Infections across our Nation
Complexity of Ecological Factors Affecting Lyme
Relationships Affecting Tick Borne Illness Incidence
<ul><li>3.   Doctors and Specialists lack  </li></ul><ul><li>Lyme education resulting in gross  </li></ul><ul><li>misdiagn...
Possible transplacental transmission of  Borrelia burgdorferi  at the time of conception and delivery?
 
<ul><li>An average of 5 years of suffering  </li></ul><ul><li>through misdiagnosis </li></ul><ul><li>before being diagnose...
 
 
 
 
 
<ul><li>Referred to </li></ul><ul><li>3-30 specialists  </li></ul><ul><li>before being properly  </li></ul><ul><li>diagnos...
URGENTLY NEEDED <ul><li>Thorough  Canadian research on Lyme in Canada, from Coast to Coast </li></ul><ul><li>Better  Testi...
<ul><li>www.murakamicentreforlyme.org </li></ul><ul><li>Not for Profit Society </li></ul><ul><li>Promotion of unbiased res...
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Lyme Disease

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Lyme presentation by Dr. Murakami, MD, Canada's leading Lyme literate physician.

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Transcript of "Lyme Disease"

  1. 1. The Modern World Epidemic Lyme Disease
  2. 2. <ul><li>Discussed This Lecture </li></ul><ul><li>What is Lyme Disease? </li></ul><ul><li>Symptoms of Lyme </li></ul><ul><li>The Controversies Surrounding Diagnosis, Testing and Treatment </li></ul>
  3. 3. What is Lyme Disease? <ul><li>A vector-borne bacterial infection caused by the borrelia bergdorferi bacterium, commonly found within the infected Ixodes tick species. (black legged tick) </li></ul><ul><li>Transmitted via tick bite & other biting insects </li></ul><ul><li>Known as the Master Mimic disease </li></ul>
  4. 7. Ixodes Pacificus Tick fully engorged
  5. 9. Barbed Mouthpiece of Tick
  6. 10. Symptoms of Lyme <ul><li>The Tick Bite (fewer than 50% recall a tick bite or get/see the rash)  </li></ul><ul><li>Rash at site of bite  </li></ul><ul><li>Rashes on other parts of your body  </li></ul><ul><li>Rash basically circular and spreading out (or generalized)  </li></ul><ul><li>Raised rash, disappearing and recurring  </li></ul><ul><li>Head, Face, Neck   </li></ul><ul><li>Unexplained hair loss  </li></ul><ul><li>Headache, mild or severe,  </li></ul><ul><li>Seizures  </li></ul><ul><li>Pressure in Head,  </li></ul><ul><li>White Matter Lesions in Head (MRI)  </li></ul><ul><li>Twitching of facial or other muscles  </li></ul>
  7. 11. <ul><li>Facial paralysis (Bell's Palsy)  </li></ul><ul><li>Tingling of nose, (tip of) tongue, cheek or facial flushing  </li></ul><ul><li>Stiff or painful neck  </li></ul><ul><li>Jaw pain or stiffness  </li></ul><ul><li>Dental problems (unexplained)  </li></ul><ul><li>Sore throat, clearing throat a lot, phlegm ( flem ), hoarseness, runny nose  </li></ul><ul><li>Eyes/Vision Double or blurry vision Increased floating spots  </li></ul><ul><li>Pain in eyes, or swelling around eyes  </li></ul><ul><li>Oversensitivity to light  </li></ul><ul><li>Flashing lights/Peripheral waves/phantom images in corner of eyes  </li></ul>
  8. 12. <ul><li>Ears/Hearing </li></ul><ul><li>Decreased hearing in one or both ears, plugged ears  </li></ul><ul><li>Buzzing in ears  </li></ul><ul><li>Pain in ears, oversensitivity to sounds  </li></ul><ul><li>Ringing in one or both ears  </li></ul><ul><li>Digestive and Excretory Systems   </li></ul><ul><li>Diarrhea  </li></ul><ul><li>Constipation  </li></ul><ul><li>Irritable bladder (trouble starting, stopping) or Interstitial cystitis  </li></ul><ul><li>Upset stomach (nausea or pain) or GERD (gastro esophageal reflux disease)  </li></ul>
  9. 13. <ul><li>Musculoskeletal System   </li></ul><ul><li>Bone pain, joint pain or swelling, carpal tunnel syndrome  </li></ul><ul><li>Stiffness of joints, back, neck, tennis elbow  </li></ul><ul><li>Muscle pain or cramps, (Fibromyalgia)  </li></ul><ul><li>Respiratory and Circulatory Systems   </li></ul><ul><li>Shortness of breath, can't get full/satisfying breath, cough  </li></ul><ul><li>Chest pain or rib soreness  </li></ul><ul><li>Night sweats or unexplained chills  </li></ul><ul><li>Heart palpitations or extra beats  </li></ul><ul><li>Endocarditis,  </li></ul><ul><li>Heart blockage  </li></ul>
  10. 14. <ul><li>Neurologic System   </li></ul><ul><li>Tremors or unexplained shaking  </li></ul><ul><li>Burning or stabbing sensations in the body  </li></ul><ul><li>Fatigue,  </li></ul><ul><li>Chronic Fatigue Syndrome,  </li></ul><ul><li>Weakness, peripheral neuropathy or partial paralysis  </li></ul><ul><li>Pressure in the head  </li></ul><ul><li>Numbness in body, tingling, pinpricks  </li></ul><ul><li>Poor balance, dizziness, difficulty walking Increased motion sickness  </li></ul><ul><li>Lightheadedness, wooziness  </li></ul>
  11. 15. <ul><li>Psychological well-being   </li></ul><ul><li>Mood swings, irritability, bi-polar disorder  </li></ul><ul><li>Unusual depression  </li></ul><ul><li>Disorientation (getting or feeling lost)  </li></ul><ul><li>Feeling as if you are losing your mind  </li></ul><ul><li>Over-emotional reactions, crying easily  </li></ul><ul><li>Too much sleep, or insomnia  </li></ul><ul><li>Difficulty falling or staying asleep  </li></ul><ul><li>Narcolepsy, sleep apnea  </li></ul><ul><li>Panic attacks, anxiety  </li></ul>
  12. 16. <ul><li>Mental Capability   </li></ul><ul><li>Memory loss (short or long term)  </li></ul><ul><li>Confusion, difficulty in thinking  </li></ul><ul><li>Difficulty with concentration or reading  </li></ul><ul><li>Going to the wrong place  </li></ul><ul><li>Speech difficulty (slurred or slow)  </li></ul><ul><li>Stammering speech  </li></ul><ul><li>Forgetting how to perform simple tasks  </li></ul><ul><li>Reproduction and Sexuality   </li></ul><ul><li>Loss of sex drive  </li></ul><ul><li>Sexual dysfunction  </li></ul><ul><li>Unexplained menstrual pain, irregularity  </li></ul><ul><li>Unexplained breast pain, discharge  </li></ul><ul><li>Testicular or pelvic pain  </li></ul>
  13. 17. <ul><li>General Well-being   </li></ul><ul><li>Unexplained weight gain, loss  </li></ul><ul><li>Extreme fatigue  </li></ul><ul><li>Swollen glands/lymph nodes  </li></ul><ul><li>Unexplained fevers (high or low grade)  </li></ul><ul><li>Continual infections (sinus, kidney, eye, etc.)  </li></ul><ul><li>Symptoms seem to change, come and go  </li></ul><ul><li>Pain migrates (moves) to different body parts  </li></ul><ul><li>Early on, experienced a &quot;flu-like&quot; illness, after which you have not since felt well.  </li></ul><ul><li>Low body temperature </li></ul><ul><li>Allergies/Chemical sensitivities  </li></ul><ul><li>Increased effect from alcohol and possible worse hangover </li></ul>
  14. 18. Examples of Erythra Migrans (Bull’s Eye Rash)
  15. 19. Current Canadian Diagnosis &Testing <ul><li>CLINICAL DIAGNOSIS* </li></ul><ul><ul><ul><li>*Canadian Doctors primarily untrained </li></ul></ul></ul><ul><ul><ul><li>to recognize symptoms for early diagnosis </li></ul></ul></ul><ul><li>BLOOD WORK: ELISA test </li></ul><ul><ul><ul><li>Negative ELISA = No Lyme </li></ul></ul></ul><ul><ul><ul><li>Positive ELISA  Western Blot (US) </li></ul></ul></ul><ul><ul><ul><li>Positive Western Blot = Lyme </li></ul></ul></ul>
  16. 20. Controversy in Testing <ul><li>Negative ELISA in Canada commonly results in positive Western Blot in US labs </li></ul><ul><li>Igenex labs controversy </li></ul><ul><li>IDSA Guidelines discovered to be seriously flawed in April 2008 </li></ul>
  17. 21. Why Testing Fails Canadians <ul><li>ELISA test known to produce notoriously false results </li></ul><ul><li>Doctors lack knowledge to recognize clinical symptoms to pursue further testing </li></ul><ul><li>False belief that Lyme doesn’t exist in many provinces </li></ul>
  18. 22. Current Canadian Treatment Protocol <ul><li>30 day antibiotic treatment is </li></ul><ul><li>currently considered sufficient </li></ul>
  19. 23. Treatment Controversy <ul><li>Many patients still exhibit symptoms after 30 day treatment </li></ul><ul><li>borrelia bergdorferi bacteria similar to that of Syphilis </li></ul><ul><ul><ul><li>Spirochete form bacteria </li></ul></ul></ul><ul><ul><ul><li>Invades every cell in body </li></ul></ul></ul><ul><li>Lays “eggs” = Cystic Form </li></ul><ul><ul><ul><li>Cystic Form not affected by same antibiotic for spirochetes </li></ul></ul></ul>
  20. 25. Lyme Bacterium Borrelia bergdorferi in spirochete formation Successfully killed by antibiotics in this stage
  21. 26. Cystic Form of Borrelia bergdorferi , Lyme bacteria Special drug treatment required during this stage
  22. 27. Why Treatment Protocol Must Change <ul><li>Cystic Form not readily accepted by physicians </li></ul><ul><li>High rate of misdiagnosis </li></ul><ul><li>Many Canadians suffering between 5-23 years needlessly </li></ul><ul><li>Canadians forced to seek out medical care in US by LLMD’s at astronomical personal expense </li></ul>
  23. 28. Why Research is Desperately Needed <ul><li>No current or accurate Lyme data exists which considers growth in US directly across our borders </li></ul>
  24. 30. With approximately 20,000 new cases reported each year, Lyme disease is the most common vector-borne disease in the United States Since Lyme disease became nationally notifiable in 1991, the annual number of reported cases has more than doubled. A more accurate estimate is suspected of being 10-fold these numbers.
  25. 31. Spread extrapolated by known Growth Rate 2006 to 2007
  26. 32. Geographical Locations of Tick Species
  27. 33. <ul><li>2. Independent /Gov’t Studies </li></ul><ul><li>are few & far between </li></ul><ul><li>and results are not </li></ul><ul><li>being considered in </li></ul><ul><li>treatment protocols </li></ul>
  28. 35. Global Warming is Affecting the Spread of Tick Borne Infections across our Nation
  29. 36. Complexity of Ecological Factors Affecting Lyme
  30. 37. Relationships Affecting Tick Borne Illness Incidence
  31. 38. <ul><li>3. Doctors and Specialists lack </li></ul><ul><li>Lyme education resulting in gross </li></ul><ul><li>misdiagnosis for thousands </li></ul><ul><li>of patients year after year </li></ul>
  32. 39. Possible transplacental transmission of Borrelia burgdorferi at the time of conception and delivery?
  33. 41. <ul><li>An average of 5 years of suffering </li></ul><ul><li>through misdiagnosis </li></ul><ul><li>before being diagnosed with Lyme </li></ul>
  34. 47. <ul><li>Referred to </li></ul><ul><li>3-30 specialists </li></ul><ul><li>before being properly </li></ul><ul><li>diagnosed with Lyme </li></ul>
  35. 48. URGENTLY NEEDED <ul><li>Thorough Canadian research on Lyme in Canada, from Coast to Coast </li></ul><ul><li>Better Testing </li></ul><ul><li>Extensive Professional Training/RE-training </li></ul><ul><li>Persecution of Lyme literate doctors must stop </li></ul>
  36. 49. <ul><li>www.murakamicentreforlyme.org </li></ul><ul><li>Not for Profit Society </li></ul><ul><li>Promotion of unbiased research, the education of Canadian medical professionals, and Assistance for victims of Lyme in Canada </li></ul><ul><li>www.drerniemurakami.com </li></ul><ul><li>Online Lyme support Forum </li></ul><ul><li>Up to date Lyme information for professionals and sufferers </li></ul>

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