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    Ro cornell 12 Ro cornell 12 Document Transcript

    • Cornell University 2.12.11 Revised 12/07 AMERICAN COLLEGE OF VETERINARY RADIOLOGY RECOGNIZED VETERINARY SPECIALTY OF RADIATION ONCOLOGY (ACVR-RO) RESIDENCY TRAINING PROGRAM RE-ACCREDITATION APPLICATIONNOTE: Some questions in this form are included for data collection purposes. The inclusion ofan item does not necessarily imply that the item is a program requirement for ACVR-ROresidency program. Please refer to the current Radiation Oncology Training Program Guidelinesfor comprehensive residency training requirements. This document may be downloaded fromMembers Only Downloads section of the ACVR website at http://www.acvr.org.APPLICATION INSTRUCTIONS:Training program directors wishing to have their programs evaluated should submit thiselectronic form and appropriate attachments electronically to the Chair of the ResidencyStandards and Evaluation Committee (RSEC) and to the Assistant Executive Director of theACVR. The application must be received by February 15 of the third year following initialprogram approval / last re-accreditation The RSEC will evaluate the application, a vote will betaken, and the results of the vote and the majority recommendation of the committee forwardedto the President of the Recognized Veterinary Specialty for consideration at Executive Council atone of the two annual meetings. For the required ACVR and ACVIM Diplomates providing consultation in medicaloncology and imaging, that are new to the program, please provide a brief 2-page curriculum vitaeand specify the number of weeks each year that the individual will be available to actively supportthe radiation oncology resident. ACVR-RO RESIDENCY STANDARD TRAINING PROGRAMREACCREDITATION APPLICATION 1. Date of Application 2/12/11 Date of Initial Program Approval 2002
    • Cornell University 2.12.11 Date of Last Re-accreditation February 2008 2. Program Director(s): (Must be a Diplomate of ACVR Recognized Veterinary Specialty of Radiation Oncology) Margaret C. McEntee Program Director’s Contact Information: Work Phone: 607-253-3208 Fax: 607-253-3055 E-mail: mcm43@cornell.edu 3. Additional ACVR-RO Diplomates supporting the program (not Program Directors) None Numbers of weeks per year an ACVR-RO Diplomate is available to resident on a daily basis. 48 4. Do you have a radiation oncology resident in training at this time? Yes No X 5. Name of resident(s) Michele Keyerleber Is/are the resident(s) in an approved Standard program or an Alternative program:
    • Cornell University 2.12.11 Standard Alternative Yes 6. Dates of training program (Please list only those dates of the actual training program. Time spent by the resident at your facility prior to beginning or following the completion of the actual training program should not be included.) Dates of training program for resident (1) (mm/dd/yy) 07/13/09 – 07/24/11 Dates of training program for resident (2) (mm/dd/yy) n/a
    • Cornell University 2.12.11 7. Location of Primary Institution Primary Site: Cornell University, College of Veterinary Medicine Department Department of Clinical Sciences Hospital/University Cornell University Hospital for Animals Address Dept. of Clinical Sciences, CVM, Cornell University City, State Zip Country Ithaca, NY 14853 USA 8. Cooperating Institution(s) (If applicable): Roswell Park Cancer Institute Department Radiation Medicine Hospital/University Roswell Park Cancer Institute Address Elm & Carlton Streets City, State, Zip, Country Buffalo, New York 14263 USA For cooperating institutions, attach letters of agreement signed on behalf of the institution(s) by appropriate individual(s). 9. Length of Training Program (months): 24
    • Cornell University 2.12.11 If greater than 2 years, will this period include 24 months of continuous training in radiation oncology? Yes No 10. Number of months dedicated solely to radiation oncology training (excluding time on Medical Oncology service, Radiology/Imaging, etc.) 18 11. Advanced Degree: Yes No Optional Masters: X PhD: X 12. Essential Program Faculty: individual faculty member may serve in only one capacity Please list all qualified faculty in support of program a. Diagnostic Radiologist(s): (Must be Diplomate(s) of the ACVR) Nathan Dykes, Peter Scrivani, Margret Thompson Number of weeks per year an ACVR – Radiology diplomate is available to resident on a daily basis. 50 Faculty member on site? Yes No X
    • Cornell University 2.12.11 If off site, please explain relationship. n/a
    • Cornell University 2.12.11 b. Medical Oncologist(s): (must be Diplomate(s) of ACVIM, Specialty of Oncology) Kelly Hume Number of weeks per year an ACVIM-Oncology Diplomate is available to resident on a daily basis. 50 Faculty member on site? Yes No X If off site, please explain relationship n/a c. Surgeon(s): (must be Diplomate(s) of the ACVS) H. Jay Harvey, James Flanders, Rory Todhunter, Ursula Krotscheck Number of weeks per year an ACVS faculty member is available to resident on a daily basis. 50 Faculty member on site? Yes No
    • Cornell University 2.12.11 X If off site, please explain relationship. n/a d. Pathologist(s): (must be Diplomate(s) of the ACVP) Sean McDonough, Donald Schlafer, Gerald Duhamel, Elizabeth Buckles, Jeanine Peters-Kennedy, Teresa Southard, Tracy Stokol (clin path), Deanna Schaefer (clin path) Number of weeks per year an ACVP faculty member is available to resident on a daily basis. 50 Faculty member on site? Yes No X If off site, please explain relationship.
    • Cornell University 2.12.11 Please list all additional board certified specialists in direct support of the program. If offsite, please explain relationship. Name Certifying College / Board Luis Campoy ACVA Robin Gleed ACVA John Ludders ACVA Andrea Looney ACVA Sydney Moise ACVIM/cardiology Marc Kraus ACVIM/cardiology Bruce Kornreich ACVIM/cardiology Curtis Dewey ACVIM/neurology Sofia Cerda-Gonzalez ACVIM/neurology Nita Irby ACVO Thomas Kern ACVO Eric Ledbetter ACVO Stephen Barr ACVIM/internal medicine Sharon Center ACVIM/internal medicine Richard Goldstein ACVIM/internal medicine William Hornbuckle ACVIM/internal medicine John Randolph ACVIM/internal medicine Kenneth Simpson ACVIM/internal medicine Daniel Fletcher ACVECC Catherine Rogers ACVECC Gretchen Schoeffler ACVECC
    • Cornell University 2.12.11 William Miller ACVD Danny Scott ACVD James K. Morrisey ABVP (avian) Ricardo de Matos ABVP (avian) Jennifer Rawlinson Dentistry Joseph Wakshlag ACVN 13. How does resident receive training in Medical Oncology? What is time allotted for this training. Please provide description of formal and informal training experiences? 2 one month rotations through the medical oncology section. On medical oncology rotation will receive new cases, see rechecks and be involved in the evaluation and treatment of both medical and radiation oncology cases. Will participate in twice daily rounds on the oncology service to discuss current cases. Medical and radiation oncology function as one service at Cornell University and there is daily discussions between the two specialties and shared responsibility for the patients. 14. How is resident trained in diagnostic imaging? What is time allotted for this training. Please provide description of formal and informal training experiences? One month rotation on the radiology service with responsibility to generate reports on imaging studies. Routine evaluation and review of all imaging studies performed on radiation therapy patients, as well as medical oncology patients. Films are routinely reviewed during the Friday morning rounds and on a daily basis during afternoon ward rounds.
    • Cornell University 2.12.11 15. How is resident trained in radiation biology? Please provide description of formal and informal training experiences? Radiation biology course. 16. How is resident trained in cancer biology? Please provide description of formal and informal training experiences? Through topic reviews and journal club articles in Monday morning rounds. Additionally opportunities arise routinely in the clinical arena during the evaluation, and management of cancer patients. 17. How is resident trained in radiation oncology physics? Please provide description of formal and informal training experiences? Radiation physics course provided by radiation physicists from Roswell Park Cancer Institute. 18. Please list any formal courses and their instructors included in the residency training curriculum. Please attach syllabi and instructor credentials for each listed course. 1. Radiation biology course, Margaret McEntee, DACVR(RO) 2. Radiation physics course, Medical physicists from Roswell Park Cancer Institute (Matthew Podgorsak, PhD, Prof., Radiation Oncology Physics)
    • Cornell University 2.12.11 19. Does the resident participate in clinical rounds on a daily basis while on clinical rotations? Is a supervising Diplomate available for the majority of rounds? If no, please describe how rounds are attended and supervised. Yes No X Comments: 20. Are formal conferences, such as clinicopathologic conferences, journal clubs, or seminars held on a weekly basis? Yes No X Comments: 21. Please provide a description of the conferences, etc., that are provided and the typical schedule. 1. Journal club – combination of journal club and topic review rounds which are held every Monday morning 8-9 AM with presentations given by medical and radiation oncology residents and faculty. 2. Tumor board rounds – combined rounds with pathology, radiology, surgery and oncology to address different tumor types presented by faculty and/or residents in the three specialties held once a month on Friday morning from 8-9AM. 3. Morbidity/mortality rounds – held once weekly includes participation of residents and faculty in oncology to discuss current challenging cases. 4. Cardiology rounds – optional, held sometimes once weekly. 5. Anesthesia lecture series – topics presented by anesthesia residents and faculty on a weekly basis. 6. Chart rounds – weekly review of radiation records and port films for current patients. 7. Histopathology rounds – pathology residents and faculty present current surgical biopsies to clinicians on a daily basis which includes seeing the slides and discussion of the findings and diagnosis.
    • Cornell University 2.12.11 8. Radiology rounds – each morning to review cases from the previous day; attended when possible and when rotating through radiology. 9. Clinical pathology rounds – 1-2 times per month with review of the cytology from recent clinical cases in the hospital presented by the clinical pathologists. 10. Surgical oncology journal club – held once a month in conjunction with the surgical faculty and residents to review topics.
    • Cornell University 2.12.11 22. Is the resident required to give one or more formal presentations at a conference or in an educational setting on a yearly basis? If yes, please describe these conferences or educational settings. Yes No X Comments: Options include but are not limited to lectures given at Cornell University to interns/residents/students/faculty, presentations at ACVR, VCS, or ACVIM annual conferences 23. How many major veterinary medical or medical meetings is each resident able to or expected to attend during his/her training program? Please list the meetings attended. None One Two > Two X Comments: Options include but are not limited to ACVR annual conference, VCS meeting, ASTRO 24. Does the training program require a research project? Please indicate the number of research projects required. Yes No Optional Number X 1 Comments: 25. Are one or more publications required as part of the training program? Yes No Number X 1 Comments:
    • Cornell University 2.12.11 26. Please indicate the availability of the following facilities or equipment. Indicate if these are available at the primary training site, or at a different location. For facilities that are not on- site, please describe the situation and availability in the space at the end of this section.Equipment / Service Available? On-Site? Yes No Yes NoMegavoltage Teletherapy Machine X XPlease specify manufacturer and model: Siemens 6 MVlinac with 5-14 MeV electrons, and MLC3D - Computer based treatment planning systemPlease specify manufacturer and model: Philips Pinnacle3 X X2D/2.5 D - Computer based treatment planning systemPlease specify manufacturer and model: X N/ALDR Brachytherapy treatment and planning X N/AHDR Brachytherapy treatment and planning X N/ADiagnostic Radiology / Imaging Services X XConventional Radiography X XFluoroscopy X XUltrasound X XNuclear Medicine X XComputed Tomography – Toshiba 16 slice multislice X XMagnetic Resonance Imaging – 1.5 T MRI X XPositron Emission Tomography X N/AIntensive Care Facility - 24 hours X XClinical Pathology capabilities: (includes CBC, serumchemistries, blood gases, urinalysis, cytology, parasitology, X Xmicrobiology,and endocrinology)Veterinary Library w/Literature Searching Capabilities X X
    • Cornell University 2.12.11Medical Library w/Literature Searching Capabilities X X 27. If any of the above equipment or facilities are available off-site, please explain how the resident can access them for case management, research, or study. Cornell Weill Medical is in NYC but electronic access available for collection. 28. Please list numbers of patients treated in the last 12 months using the listed radiation treatment modalities. Modality Number Treated Megavoltage Gamma / X-ray Teletherapy 50 LDR Brachytherapy 0 HDR Brachytherapy 0 Injectable Radionuclide therapy Radioiodine Done through radiology (50) Other (please specify) 0 90 Strontium Pleisotherapy 5 Other - please specify N/A
    • Cornell University 2.12.11 29. Describe procedures for resident record recording of radiation treatment details of all patients. A detailed record is compiled for each radiation patient including: detailed treatment chart to record daily treatments by field, hand calculations on all computer plans, daily progress notes, medical history summarized by resident, physical examination performed by resident, diode measurements recorded, anesthesia record (by technicians), and record includes copies of blood work, imaging reports, histopathology reports, etc. A complete paper record is maintained for each patient and each patient is entered into the computer database. 30. What procedures are in place to facilitate collection of follow up information of patients treated? Computer database of radiation patients tracks routine recheck times. If a patient does not return to Cornell for routine rechecks then phone calls are placed by the radiation resident, and/or radiation oncology technicians to the owner and/or referring veterinarian to obtain follow up. 31. By what mechanisms and how often are residents evaluated? Please attach form used in this evaluation (required). Residents are evaluated by the 3rd and 4th year veterinary students that rotate through the oncology service and provided with a summary of the evaluations every 6 months. These evaluations are done electronically. Residents are evaluated by the medical and radiation oncology faculty every 6 months (see attached form) and a formal review of their performance and progress is provided in a meeting between the resident and the radiation oncology program director.
    • Cornell University 2.12.11 32. Please list the residents who have completed the training program including the year that each individual’s training program ended. If at all possible, please provide an address, and any information you have on the status of each individual with respect to the board certification process. John Farrelly completed residency in 2004 and passed the certifying exam in 2004. Current address is as follows: Head, Radiation Therapy The Animal Medical Center 510 East 62nd Street New York, NY 10021 Blaise Burke completed residency in 2004/2005 and passed the certifying exam in 2005 Current address is as follows Veterinary Specialty Hospital 10435 Sorrento Valley Road San Diego, CA 92121 Tracy Gieger completed residency in 2007 and passed the certifying exam in 2007 Assistant Professor at Louisiana State University, School of Veterinary Medicine Skip Bertram Drive Baton Rouge, LA 70803 33. Please list any additional information of interest in support of this residency re-accreditation application. NYS Diagnostic Laboratory on site. DNA bank and active program. Currently have an internal cancer biology training grant with intent to apply for an NIH funded training grant.
    • Cornell University 2.12.11 Attachments: Please attach the following documents to the application if applicable. Please mark box to indicate which documents are included. Please list any additional documents attached in support of this application. Attached? Documents YES Twenty-four (24) month calendar of resident’s activities - Required YES CV - ACVR-RO Diplomate - Program Director(s) - Required N/A CV - ACVR-R Diplomate(s) - Requiredividuals YES (new) CV - ACVIM-O Diplomate(s) - Required YES Syllabi of formal course work included in the training program - Required YES (CV) Credentials of instructors providing formal course work - Required YES Forms used in resident evaluation - Required YES Letters of agreement from cooperating institutions - Required
    • Cornell University 2.12.11 Radiation Oncology Residency CalendarJuly Aug Sept Oct Nov Dec Jan Feb Mar April May JuneMO RO RO RO Rad RO* RO RO RO RO Anes* ROMO RO RO RO RO RO* RO RO RO RO RO StudyMO – medical oncology (2 months total): Responsible for receiving both medical and radiation oncologypatients that present for evaluation (diagnostics to include blood work, imaging, biopsy, etc.) and therapy,and to see recheck appointments with an emphasis on the radiation oncology patients that present forrechecks. Participate in twice daily ward rounds to discuss current patients. Attend and also routinelyresponsible for morning teaching rounds with 3rd and 4th year veterinary students that are rotating throughthe oncology service.RO – radiation oncology (18 months total): To consult on all potential radiation therapy patients thatpresent to oncology or present to other services in the hospital. Develop a diagnostic and therapeuticplan. Review all imaging studies and the medical record for radiation patients. Perform a physicalexamination on all radiation patients prior to initiation of a course of radiation therapy. Position patients(vac-lok) for CT imaging for radiation treatment planning. Radiation treatment planning both CT basedcomputer assisted 3D radiation treatment planning and manual planning. Involved in the daily treatmentof radiation patients including assisting with anesthesia, patient positioning and delivery of radiationtherapy. Telephone consultations with referring veterinarians on potential radiation patients.Rad – radiology (1 month total): To attend daily radiology rounds, observe image acquisition, and imageinterpretation under the guidance of the radiology residents and faculty. To generate imaging reports tobe reviewed by the radiology faculty.Anes – anesthesia (2 weeks total): Anesthetize small animal patients under the direction of the anesthesiaservice. Participate in the daily anesthesia rounds while on the anesthesia service. Also, to attendanesthesia lecture series when possible and for relevant topics on anesthetics and management of patientsunder anesthesia.Study – (1 month total): To be spent preparing for the radiation oncology certifying examination.* For each of these one month blocks half of the time is to be spent on the designated service and theother two weeks are for vacation (10 days total each year) and two weeks optional for work on a projector time on another service such as pathology or clinical pathology.
    • Cornell University 2.12.11 RADIATION BIOLOGY Topics to be coveredRadiation chemistryCellular responses to DNA damageSurvival curvesSublethal damage repair, potentially lethal damage repairLinear energy transferRelative biological effectivenessRadiation-induced cell cycle effects and age response through the cell cycleMutagenesis, transformation and carcinogenesisThe oxygen effect and reoxygenationRadiosensitizers, and radioprotectorsNormal and tumor cell kineticsEarly and late effects4 R’s of radiotherapyRadiation and chemotherapy interactionsDose rate and dose fractionation effectsHyperthermiaMiscellaneous topics
    • Cornell University 2.12.11 RADIATION PHYSICS Topics to be coveredAtomic and nuclear structureRadioactive decayProperties and production of particulate and electromagnetic radiationInteractions of electromagnetic radiation with matterInteractions of particulate radiation with matterQuantification and measurement of doseCharacteristics of photon beamsDosimetry of photon beams in a homogenous water phantomDosimetry of photon beams in a patientDosimetry of electron beamsBrachytherapyRadiation protectionOther topics
    • Cornell University 2.12.11 Radiation Oncology Resident Evaluation Cornell UniversityResident Name ______________________________Evaluator(s) _________________________________________Period covered by this evaluation ________________________Year of program : 1 1 2 1 CATEGORY 1 2 3 4 NACLINICAL ABILITY Knowledge (theory/principle, current literature) Application of knowledge, logic Quality of patient management (diagnosis, treatment, follow-up) Patient care Diagnostic/technical skills Instructional skill Oral and written presentation OtherSENSE OF RESPONSIBILITY Initiative, motivation Judgement Reliability Organization Attendance at rounds and seminars Punctuality OtherINTERPERSONAL SKILLS Communication with : Clients Faculty Students Technical and administrative staff Referring veterinarians Other house officers Performance under stress Receptiveness toward guidance OtherHOSPITAL POLICIES AND PROCEDURES Medical records, including reports (timeliness, accuracy, completeness) Procedures (anesthesia scheduling, admissions/discharge) OtherSTUDENT EVALUATION OF PERFORMANCEPROGRESS ON RESIDENCY AND BOARD REQUIREMENTSOVERALL EVALUATION1 – frequently exceeds expectations/standards2 – fully achieves expectations/standards3 – needs improvement
    • Cornell University 2.12.114 – fails to achieve expectations/standardsNA = not applicableResidents are expected to achieve a “fully achieves expectations/standards” in each category. For categories with a“frequently exceeds standards” score, residents should be acknowledged and commended. Suggestions forimprovement with a reasonable time frame should be addressed for categories with a “needs improvement” or “failsto achieve expectations/standards” score. There should be evidence of improvement at the time of the nextevaluation. If an overall score of “fails to achieve expectations/standards” is given at any time, a review of theresident is required to determine whether the resident will continue in his/her program.Written comments by faculty:Written summary of student evaluations:I have read and understand this evaluation.Signed,Resident ______________________________________Advisor _______________________________________Date __________________________________________
    • Cornell University 2.12.11
    • Cornell University 2.12.11
    • BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Margaret C. McEntee Professor of Oncology eRA COMMONS USER NAME (credential, e.g., agency login) Department Chair, Dept. of Clinical Sciences MCMCENTEE EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable) Cornell University, Ithaca, New York DVM 06/86 Veterinary Medicine North Carolina State University, Raleigh, NC Internship 07/86-06/87 Rotating Internship North Carolina State University, Raleigh, NC Residency 07/89-06/91 Medical Oncology North Carolina State University, Raleigh, NC Residency 07/91-06/93 Radiation OncologyA. Positions and HonorsPositions and Employment: 1994-1997 Staff Oncologist, Animal Medical Center, New York, New York 1997-2000 Assistant Clinical Professor, University of California Davis, School of Veterinary Medicine 2000-2008 Associate Professor, Cornell University, College of Veterinary Medicine, and Co- Director of the Sprecher Institute for Comparative Cancer Research (2005-present) 2008-present Professor, Cornell University, College of Veterinary Medicine 2010-present Interim Chair, Department of Clinical Sciences, Cornell University, College of Veterinary MedicineHonors and Professional Service: 1978 Phi Beta Kappa (University of Vermont) 2000-2002 President, American College of Veterinary Radiology, Radiation Oncology Affiliate 2006 Phi Zeta, Alpha Chapter, Cornell UniversityAmerican College of Veterinary Internal Medicine – board certified in medical oncology (1993)American College of Veterinary Radiology – board certified in radiation oncology (1994)American Society for Radiation Oncology, memberAmerican Society of Clinical Oncology, memberB. Selected peer-reviewed publications1. McEntee MC, Silverman JA, Rassnick K, Zgola M, Chan AO, Tau PT, Page RL. Enhanced bioavailability of oral docetaxel by co-administration of cyclosporine A in dogs and rats. Vet Comp Oncol 2003;1:105- 112.2. McEntee MC, Page RL, Theon AP, et al. Malignant tumor formation in dogs previously irradiated for acanthomatous epulis. Vet Rad Ultrasound 2004;45:357-361.3. McEntee MC, Rassnick KM, Lewis LD, Zgola M, Page RL. Phase I and pharmacokinetic evaluation of oral docetaxel and cyclosporine in tumor-bearing dogs. Am J Vet Res 2006;67:1057-1062.4. McEntee MC, Rassnick KM, Bailey DB, Balkman CE, Flanagan JL, Beaulieu BB, Zgola MM, Lewis LD, Page RL. Phase I and pharmacokinetic evaluation of the combination of orally administered docetaxel and cyclosporine A in tumor-bearing cats. J Vet Intern Med 2006;20(6):1370-1375.5. Turrel JM, McEntee MC, Erb HN, Burke BP, Page RL. 131I treatment for advanced thyroid tumors: a retrospective study of 39 dogs (1990-2003). J Am Vet Med Assoc 2006;229:542-548.6. Kim Y, Selvaraj V, McEntee MC, Travis AJ. Recipient preparation and mixed germ cell isolation for spermatogonial stem cell transplantation in domestic cats. Journal of Andrology 2006;27:248-256.7. Turrel JT, Farrelly J, Page RL, McEntee MC. Strontium-90 irradiation for feline cutaneous mast cell tumors: a retrospective study of 35 cats (1992-2002). J Am Vet Med Assoc 2006;228:898-901.
    • 8. McEntee MC. Portal radiography in veterinary radiation oncology: options and considerations. Vet Radiol Ultrasound 2008;49(1) Suppl 1:S57-S61.9. McEntee MC, Steffey M, Dykes NL. Potential utility of surgical hemoclips in radiation treatment planning. Vet Radiol Ultrasound 2008;49:395-399.10. Kim Y, Turner D, Nelson J, Dobrinski I, McEntee MC, Travis AJ. Production of donor-derived sperm after spermatogonial stem cell transplantation in the dog. Reproduction 2008;136:823-831.11. Wakshlag JJ, Balkman CE, Morgan SK, McEntee MC. Evaluation of the protective effects of all-trans- astaxanthan on canine osteosarcoma cell lines. Am J Vet Res 2010;71:89-96.12. Webster JD, Dennis MM, Dervisis N, Heller J, Bacon NJ, Bergman PJ, Bienzle D, Cassali G, Castagnaro M, Cullen J, Esplin DG, Pena L, Goldschmidt MH, Hahn KA, Henry CJ, Hellmen E, Karnstock D, Kirpensteijn J, Kitchell BE, Amorim RL, Lenz SD, Lipscomb TP, McEntee M, McGill LD, McKnight CA, McManus PM, Moore AS, Moore PF, Moroff SD, Nakayama H, Northrup NC, Sarli G, Scase T, Sorenmo K, Schulman FY, Shoieb AM, Smedley RC, Spangler WL, Teske E, Thamm DH, Valli VE, Vernau W, van Euler H, Withro SJ, Weisbrode SE, Yager J, Kiupel M. Recommended guidelines for the conduct and evaluation of prognostic studies in veterinary oncology. Vet Pathol 2010 Jul 27 [Epub ahead of print].13. Stein R, Balkman C, Chen S, Rassnick K, McEntee M, Page R, Goldenberg DM. Evaluation of anti-human leukocyte antigen-DR monoclonal antibody therapy in spontaneous canine lymphoma. Leukemia and Lymphoma, 2010, in press.
    • BIOGRAPHICAL SKETCH DO NOT EXCEED TWO PAGESNAME POSITION TITLE Instructor, Section of OncologyHume, Kelly R. Department of Clinical SciencesEDUCATION/TRAINING: Begin with undergraduate BA/BS or equivalent. Include postdoctoral training (internship/residency/fellowship, etc.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable) BS with University of Wisconsin-Madison, Madison WI Highest 1995-1999 Animal Science Distinction DVM cum Auburn University, Auburn AL 1999-2003 Veterinary Medicine laude Rotating Intern (Small University of Georgia, Athens GA 2003-2004 Animal Medicine and Surgery) Specialty Intern University of Georgia, Athens GA 2004-2005 (Oncology) Resident in Medical North Carolina State University, Raleigh NC 2005-2008 Oncology Clinical Fellow, Cornell University, Ithaca NY 2008-2010 Biomedical Sciences A. Certification 2008 – Diplomate of the American College of Veterinary Internal Medicine, Specialty of Oncology B. Positions and Honors Positions and Employment 2010-present – Instructor, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University Other Experience and Professional Memberships 2010 Reviewer, Journal of Feline Medicine and Surgery 2010-present Cornell University Comparative Cancer Biology Training Program 2009-present New York Academy of Sciences 2008-present American College of Veterinary Internal Medicine Veterinary Cooperative Oncology Group 2004-present Veterinary Cancer Society 2003-2005 American Veterinary Medical Association 2004 Comparative Oncology Program – University of Georgia 2003-2004 American Association of Feline Practitioners
    • Academic and Professional Honors 2009 Cornell University-Pfizer Sponsored Attendee, Clinician Scientist Training Workshop, University of Wisconsin-Madison 2003 Excellence in Feline Medicine and Surgery, AAFP Senior Student Award, College of Veterinary Medicine, Auburn University 2002 Community Involvement Award, College of Veterinary Medicine, Auburn UniversityC. Selected Peer-reviewed Publications Pavlova IP, Hume KR, Yazinski SA, Peters RM, Weiss RS, Webb WW. Multiphoton microscopy as a diagnostic imaging modality for lung cancer. Proc Soc Photo Opt Instrum Eng 2010;7569:756918. Northrup NC, Gieger TL, Kosarek CE, Saba CF, LeRoy BE, Wall TM, Hume KR, Childress MO, Keys DA. Mechlorethamine, procarbazine and prednisone for the treatment of resistant lymphoma in dogs. Veterinary and Comparative Oncology 2009;7:38-44. Hume KR, Johnson JL, Williams LE. Adverse effects of concurrent carboplatin chemotherapy and radiation therapy in dogs. Journal of Veterinary Internal Medicine 2009;23:24-30.
    • BIOGRAPHICAL SKETCH DO NOT EXCEED TWO PAGESNAME POSITION TITLE Senior Lecturer in RadiologyNathan L. Dykes Department of Clinical SciencesEDUCATION/TRAINING: Begin with undergraduate BA/BS or equivalent. Include postdoctoral training (internship/residency/fellowship, etc.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable)Rutgers University; New Brunswick, NJ BS 1966-70 Animal ScienceCornell University; Ithaca, NY DVM 1970-74 Veterinary MedicineRowley Memorial Animal Hosp.; Springfield, MA Internship 1974-75 Small Animal Med/SurgUniversity of Pennsylvania; Philadelphia, PA Resident 1986-89 Radiology A. Certification American College of Veterinary Radiology, 1991 B. Positions and Honors Positions and Employment 2006-present Senior Lecturer, Radiology, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 1996-2006 Lecturer, Radiology, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 1991-96 Assistant Professor, Radiology, College of Veterinary Medicine, Cornell University, Ithaca, NY 1989-91 Lecturer, Radiology, School of Veterinary Medicine, Philadelphia, PA 1986-89 Resident, Radiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 1984-86 Linden Heights Animal Hospital, Winchester, VA Small Animal Practice 1981-84 Loudoun Veterinary Service, Inc. Purcellville, VA Small Animal Practice 1976-81 Rowley Memorial Animal Hospital, Springfield, MA - Staff Surgeon 1975-76 Millar Animal Hospital, Deal, NJ Staff Veterinarian Other Experience and Professional Memberships American Veterinary Medical Association American Animal Hospital Association American College of Veterinary Radiology New York Veterinary Medical Association Radiological Society of North America Society for Digital Imaging
    • Academic and Professional Honors1970 Rutgers University, Graduation with Honors1994 Yearbook Dedication, Class of 1994, College of Veterinary Medicine, Cornell1994 Faculty Mentor Award, Multi-ethnic Student Veterinary Association, Class of 1994, College of Veterinary Medicine, Cornell1994 Norden Distinguished Teacher Award, College of Veterinary Medicine, Cornell2001 Distinguished Service Award, Southern Tier Veterinary Medical AssociationC. Selected Peer-reviewed Publications 1. Clarifying some aspects of diagnostic-accuracy research. Scrivani PV, Dykes NL, Erb HN. Vet Radiol Ultrasound. 2004 Sep-Oct;45(5):419-23. 2. Effect of glomerular filtration rate on clearance and myelotoxicity of carboplatin in cats with tumors. Bailey DB, Rassnick KM, Erb HN, Dykes NL, Hoopes PJ, Page RL. Am J Vet Res. 2004 Nov;65(11):1502-7. 3. Association of the risk of development of hypothyroidism after iodine 131 treatment with the pretreatment pattern of sodium pertechnetate Tc 99m uptake in the thyroid gland in cats with hyperthyroidism: 165 cases (1990-2002). Nykamp SG, Dykes NL, Zarfoss MK, Scarlett JM.. J Am Vet Med Assoc. 2005 May 15;226(10):1671-5 4. Somatostatin receptor imaging in vivo by planar scintigraphy facilitates the diagnosis of canine insulinomas. Garden OA, Reubi JC, Dykes NL, Yeager AE, McDonough SP, Simpson KW. J Vet Intern Med. 2005 Mar-Apr;19(2):168-76. 5. Accuracy of increased thyroid activity during pertechnetate scintigraphy by subcutaneous injection for diagnosing hyperthyroidism in cats. Page RB, Scrivani PV, Dykes NL, Erb HN, Hobbs JM. Vet Radiol Ultrasound 6. Visually lossless compression of digitized radiographs based on contrast sensitivity and visual masking. Chandler DM, Dykes NL, Hemami SS,, Proc. Medical Imaging 2005, San Diego, CA, 2005. 7. Evaluation of serum iohexol clearance for use in predicting carboplatin clearance in cats. Bailey DB, Rassnick KM, Prey JD, Dykes NL. Am J Vet Res. 2009 Sep;70(9):1135-40. 8. Evaluation of quantitative trait loci for hip dysplasia in Labrador retrievers. Phavaphutanon J, Mateescu RG, Tsai KL, Schweitzer PA, Corey EE, Vernier-Singer MA, Williams AJ, Dykes NL, Murphy KE, Lust G, Todhunter RJ. Am J Vet Res. 2009 Sep;70(9):1094-101. 9. Estimation of heritabilities, genetic correlations and breeding values of four traits that collectively define hip dysplasia in dogs. Zhang Z, Zhu L, Sandler J, Freidenberg SS, Egelhoff J, Williams AJ, Dykes NL, Hornbuckle W, Krotscheck U, Moise NS, Lust G, Todhunter RJ. Am J Vet Res. 2009 Apr;70 (4):483-92.
    • BIOGRAPHICAL SKETCH Provide the following information for the key personnel in the order listed for Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES.NAME POSITION TITLE Scrivani, Peter Vincent Assistant Professor of Veterinary ImagingEDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable)Cornell University D.V.M. 1993 Veterinary MedicineSection A and B should not exceed two pages:A. Positions and HonorsPositions and Employment:1993-1994 Veterinarian, Liverpool Veterinary Hospital, Liverpool, NY1994-1997 Radiology Residency, Ohio State University, College of Veterinary Medicine1997-1998 Instructor, Cornell University College of Veterinary Medicine1998-2005 Lecturer, Cornell University College of Veterinary Medicine2005-present Assistant Professor, Cornell University College of Veterinary MedicineOther Experience and Professional Memberships:1990-present American Veterinary Medical Association1994-present American College of Veterinary Radiology1998-present New York State Veterinary Medical Society2000-present Phi Zeta, Alpha Chapter2001-present World Association of Veterinary Anatomists2006-present ACVR CT/MRI SocietyHonors:1996, 1997 Clinical Teaching Excellence Award, Pfizer Animal Health and Ohio State University1997 Service Award, Ohio State UniversityB. Selected peer-reviewed publications (last 3 years only) 1. Freer  SR,  Scrivani  PV.  Post-­‐operative  susceptibility  artifact  during  magnetic  resonance   imaging  of  the  vertebral  column  in  two  dogs  and  a  cat.  Vet  Radiol  Ultrasound   2008;49(1):30-­‐34.   2. Gold  JR,  Divers  TJ,  Miller  AJ,  Scrivani  PV,  Perkins  GA,  Van  Biervliet  J,  deLahunta  A.   Cervical  vertebral  spinal  hematomas  in  4  horses.  J  Vet  Intern  Med  2008;22(2):481-­‐485.   3. Burns  GO,  Scrivani  PV,  Thompson  MS,  Erb  HN.  Relation  between  age,  body  weight   and  medial  retropharyngeal  lymph  node  size  in  apparently  healthy  dogs.  Vet  Radiol   Ultrasound  2008;49(3):277-­‐281.   4. Winegardner  KR,  Scrivani  PV,  Gleed  RD.  Lung  expansion  in  the  diagnosis  of  lung   disease.  Compendium  Contin  Educ  Vet  2008;30(9):479-­‐489.   5. Pownder  S,  Scrivani  PV.  Non-­‐selective  computed  tomography  angiography  of  a   vascular  ring  anomaly  in  a  dog.  J  Vet  Cardiol  2008;10(2):125-­‐128.    
    • 6. Cerda-­‐Gonzalez  S,  Dewey  CW,  Scrivani  PV,  Kline  K.  Imaging  features  of  atlanto-­‐ occipital  overlapping  in  dogs.  Vet  Radiol  Ultrasound  2009;50(3):264-­‐268.  7. Scrivani  PV,  Freer  SR,  Dewey  CW,  Cerda-­‐Gonzalez  S.  Cerebrospinal  fluid  signal-­‐void   sign  in  dogs.  Vet  Radiol  Ultrasound  2009;50(3):269-­‐275.  8. Dewey  CW,  Scrivani  PV,  Krotscheck  U,  Cerda-­‐Gonzalez  S,  Bailey  KS,  Marino  DJ.   Intracranial  arachnoid  cysts  in  dogs.  Compendium  Contin  Educ  Vet  2009;31(4):160-­‐168.  9. Freer  SR,  Scrivani  PV,  Erb  HN.  Associations  between  cardiopulmonary  variables  and   the  cerebrospinal  fluid  signal-­‐void  sign  in  small-­‐breed  dogs.  Vet  Radiol  Ultrasound   2009;50(4):360-­‐363.  10. Dewey  CW,    Cerda-­‐Gonzalez  S,  Scrivani  PV,  Looney  AL.  Surgical  stabilization  of  a   craniocervical  junction  abnormality  with  atlanto-­‐occipital  overlapping  in  a  dog.   Compendium  Contin  Educ  Vet  2009;31(10):E1-­‐E6.  11. Dawson  DR,  Scrivani  PV,  Schaefer  DMW,  Bogdanovic  LB,  Ainsworth  DM.  Epitheliod   variant  of  hemangiosarcoma  in  a  gelding.  Equine  Veterinary  Education  2009;21(10):519-­‐ 524.  12. Pownder  SL,  Scrivani  PV,  Bezuidenhout  A,  Divers  DJ,  Ducharme  NG.  Computed   tomography  of  temporal  bone  fractures  and  temporal  region  anatomy  in  horses.    J  Vet   Intern  Med  2010;24:398-­‐406.  13. Levine  JM,  Scrivani  PV,  Divers  TJ,  Furr  M,  Mayhew  IJ,  Reed  S,  Levine  GJ,  Foreman  JH,   Boudreau  C,  Credillle  BC,  Tennent-­‐Brown  B,  Cohen  ND.    Multicenter  case-­‐control  study   of  signalment,    diagnostic  features  and  outcome  associated  with  cervical  vertebral   malformation-­‐malarticulation  in  horses.  J  Am  Vet  Med  Assoc  2010;237(7):812-­‐822.  14. Scrivani  PV,  Levine  JM,  Holmes  NL,  Furr  M,  Divers  TJ,  Cohen  HD.  Observer  agreement   study  of  cervical-­‐vertebral  ratios  in  horses.  Equine  Vet  J,  DOI:  10.1111/j.2042-­‐ 3306.2010.00300.x  15. Sharma  A,  Thompson  MS,  Scrivani  PV,  Dykes  NL,  Yeager  AE,  Freer  SR,  Erb  HN.   Comparison  of  radiography  and  ultrasonography  for  diagnosing  small-­‐intestinal   mechanical  obstruction  in  vomiting  dogs.  Vet  Radiol  Ultrasound,  DOI:  10.1111/j.1740-­‐ 8261.2010.01791.x  
    • BIOGRAPHICAL SKETCH DO NOT EXCEED TWO PAGES. NAME POSITION TITLE Margret Sara Thompson Lecturer, Imaging EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable) Smith College, Northampton, MA A.B. 1985-89 Architecture Boston University, Boston, MA M.Ed. 1992-93 Counseling Psychology Tufts University, N. Grafton, MA D.V.M. 1994-98 Veterinary Medicine Angell Memorial Animal Hospital, Boston, MA Internship 1998-99 Rotating Internship University of Florida, Gainesville, FL Residency 1999-2002 Veterinary RadiologyA. Certification – American College of Veterinary Radiology- board certified in radiology (2002)B. Positions and HonorsPositions and Employment:2002-2006 Clinical Assistant Professor, University of Florida, College of Veterinary Medicine, Gainesville,FL2004-2006 Section Chief-Imaging, University of Florida, College of Veterinary Medicine, Gainesville,FL2006-current Lecturer, Cornell University, College of Veterinary Medicine, Ithaca, NY2010-current Section Chief-Imaging, Cornell University, College of Veterinary Medicine, Ithaca, NYOther Experience and Professional Memberships:American College of Veterinary RadiologyAmerican Veterinary Medical AssociationAcademic and Professional HonorsUniversity of Florida, Health Science Center Superior Accomplishment Award – Digital Radiography Project 2004University of Florida, College of Veterinary Medicine 1st Annual SACS Departmental Service Award 2004 Support Services Resident of the Year 2001 Support Services Resident of the Year 2002 11th Annual Resident Seminar of the Year, Winner 2002 10th Annual Resident Seminar of the Year, Co-Winner 2001Tufts University, School of Veterinary Medicine Student Pharmacia & Upjohn Small Animal Proficiency Award 1998 Eastman Kodak Radiology Achievement Award 1998 Phi Zeta Veterinary Honor Society Member 1998 NIH Student Research Competition - 2nd Place 1996 Deans Commendation 1996 – 1998C. Selected peer-reviewed publicationsSharma A, Thompson MS, Scrivani PV, Dykes NL, Yeager AE, Freer SR, Erb HN. Comparison ofRadiography and Ultrasonography of Small-Intestinal Mechanical Obstruction in Vomiting Dogs. Article firstpublished online: 28 DEC 2010 | DOI: 10.1111/j.1740-8261.2010.01791.xMulz JM, Kraus MS, Thompson MS, Flanders JA. Cranial vena caval syndrome secondary to central venousobstruction associated with a pacemaker lead in a dog. Journal of Veterinary Cardiology, 2010 Dec; 12 (3):217-223.
    • Sharma A, Thompson MS, Schnabel LV, Mete A, Hackett R. Imaging Diagnosis-Equine Nasal SeptalThickening due to Chronic Chondritis. Vet Radiol Ultrasound, 2010 Jan-Feb: 51(1):65-8.Flanders JA, Thompson MS. Dyspnea caused by epiglottic retroversion in two dogs. J Am Vet Med Assoc.2009 Dec 1; 235 (11): 1330-5.Hill RC, Ginn PE, Thompson MS, Seguin MA, Miller D, Taylor DP. Endobronchial polyp derived from amyxosarcoma in the lung of a dog J Am Anim Hosp Assoc. 2008 Nov-Dec:44 (6):327-34.Marolf A, Blaik M, Ackerman N, Watson E, Gibson N, Thompson M. Comparison of computed radiographyand conventional radiography in detection of small volume pneumoperitoneum. Vet Radiol Ultrasound. 2008May-Jun;49(3):227-32.Burns, GO, Scrivani PS, Thompson MS, Erb H. Relation between age, body weight, and medialretropharyngeal lymph node size in apparently healthy dogs. Vet Radiol Ultrasound. 2008 May-Jun;49(3):277-81.Scrivani PV, Thompson MS, Winegardner K, Dewey C. Association between frontal-sinus size andsyringohydromyelia in small-breed dogs: 62 cases (2004-2006). Am J Vet Res. 2007 Jun;68(6):610-3.Gardner A, Thompson MS, Heard D. Radiographic Evaluation of Cardiac Size in Flying Fox Species(Pteropus rodricensus, P. hypomelanus and P. vampyrus). J Zoo Wildl Med. 2007 Jun;38(2):192-200.Nelligan MR, Wheeler JL, Lewis DD, Thompson MS. Bilateral correction of metatarsal rotation in a dogusing circular external skeletal fixation. Australian Veterinary Journal 2007 85(8) 332-336.Adin CA, Sereda CW, Thompson MS, Wheeler JL, Archer LL. Use of a percutaneously controlled hydraulicoccluder in the treatment of canine intrahepatic shunts: short-term outcome in 10 dogs. J Am Vet Med Assoc.229(11):1749-55, 2006.Marolf A, Specht A, Castleman W, Thompson MS. Radiographic and Urethrographic Findingsassociated with a Penile Hemangiosarcoma. Vet Radiol Ultrasound. 47(5) 474-475, 2006.Farese JP, Milner R, Thompson MS, et al. Stereotactic radiosurgery for the treatment of osteosarcomasinvolving the distal portions of the limbs in dogs. J Am Vet Med Assoc 225(10): 1572-87, 2005.Guille AE, Lewis DD, Anderson TP, Beaver DP, Carrera-Justiz SC, Thompson MS, et al. Evaluation ofsurgical repair of humeral condylar fractures using self-compressing Orthofix pins in 23 dogs. Vet Surg33(4):314-22, 2004.Gunkel CI, Valverde A, Robertson SA, Thompson MS, et al. Treatment for a severe reaction tointravenous administration of diatrizoate in an anesthetized horse. J Am Vet Med Assoc 224(7):1143-6, 2004.Thompson MS, Graham JP, Mariani CL. Helical CT Angiography: Diagnosis of a Porto-Azygous Shunt.Vet Radiol Ultrasound 44(3):287-291, 2003.Dhar AK, Thompson MS, et al. Determination of cDNA Sequence and mRNA Expression of Interleukin 1Receptor Antagonist in Horses. Am J Vet Res 67(8):920-4, 2000.
    • Cornell University 2.12.11 February 2011 CURRICULUM VITAE MATTHEW B. PODGORSAK, PHD, FAAPM, DABMPPersonal Information: Home Address: Work Address: Department of Radiation Medicine Roswell Park Cancer Institute Elm and Carlton Streets Buffalo, New York 14263 Tel.: Tel.: FAX: e-mail:Education: CEGEP: Marianopolis College, Montréal, Québec (1982-84) Major field: Health Sciences Undergraduate: McGill University, Montréal, Québec (1984-87) Major field: Physics Graduate: McGill University, Montréal, Québec (1987-89) Major field: Medical Physics University of Wisconsin, Madison, Wisconsin (1990-93) Major field: Medical PhysicsDegrees: D.E.C. (Health Sciences) Marianopolis College, Montréal (June 1984) B.Sc. (Hon. Physics) McGill University, Montréal (June 1987) M.Sc. (Physics) McGill University, Montréal (February 1990) Thesis: Fricke radiation dosimetry using NMR Ph.D. (Medical Physics) University of Wisconsin, Madison (December 1993) Thesis: Radiation parameters of high dose rate Iridium-192 sourcesPresent Appointments:• September 1998 to present: Roswell Park Cancer Institute, Department of Radiation Medicine: Chief Physicist.• December 1993 to present: State University of New York at Buffalo, Department of Radiation Oncology: Clinical Assistant Professor.• September 1997 to present: Erie Community College, Department of Physics: Adjunct Clinical Professor.
    • Cornell University 2.12.11• December 2002 to present: State University of New York at Buffalo, Department of Molecular and Cellular Biophysics: Associate Professor.• March 2008 to present: State University of New York at Buffalo, Department of Physiology and Biophysics: Research Assistant Professor.Professional Certifications: Diplomate, American Board of Medical Physics (ABMP), Certified in Radiation Oncology Physics, 1997, re-certified 2007. Diplomate, American Board of Radiology (ABR), Letter-of-Equivalence, Certified in Radiologic Physics, 2002.Professional Affiliations: American Association of Physicists in Medicine (AAPM) (member since 1988). Canadian Organization of Medical Physicists (COMP) (member since 1990). Upstate New York Chapter of the AAPM (member since 1997). American College of Medical Physics (ACMP) (member since 2001). American Society for Therapeutic Radiology and Oncology (ASTRO) (member since 2008).Awards, Fellowships, and Honors:- Fellow, American Association of Physicists in Medicine (AAPM), 2009.Grant Funding:- Principal Investigator, “Image-guided tracking of tumor motion and its relation to PTV size,” National Science Foundation (NSF) / University at Buffalo subaward, September 1, 2010 to August 31, 2011: $21,000.Committee Memberships:- Radiation Safety Committee, Roswell Park Cancer Institute, 1997 – present- Quality Improvement Committee, Department of Radiation Medicine, Roswell Park Cancer Institute, 2001 – present.- Quality Assurance Committee, Department of Radiation Medicine, Roswell Park Cancer Institute, 2001 – present.- Continuing Education Committee, American College of Medical Physics (ACMP), January 2004 – December 2007.