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  1. 1. MICHIGAN TECHNOLOGY TRI-CORRIDOR FUND REQUEST FOR PROPOSALS FISCAL YEAR 2005 COMPETITION Briefing Session October 26, 2004 4:00 - 5:30 pm South Lecture Hall Med Sci II
  2. 2. MTTC FUND RFP <ul><li>Funding Categories </li></ul><ul><li>Category I (basic research fund): For basic research in health-related areas with eventual application to life sciences industry and product development. </li></ul><ul><ul><li>Eligible applicants include Michigan universities and nonprofit research institutes. </li></ul></ul><ul><ul><li>Should enhance the research capacity and activity of the state to attract or develop companies, researchers, or students to Michigan. </li></ul></ul><ul><ul><li>Preference given to multi-institution, multi-disciplinary research centers. </li></ul></ul>
  3. 3. MTTC FUND RFP <ul><li>Funding Categories (cont’d) </li></ul><ul><li>Category II (applied research fund): To fund collaborative translational research, testing, or develop of emerging discoveries in life sciences. </li></ul><ul><ul><li>Eligible applicants include universities, nonprofit research institutes, and private research facilities. </li></ul></ul>
  4. 4. MTTC FUND RFP <ul><li>Funding Categories (cont’d) </li></ul><ul><li>Category III (commercialization development fund): To fund collaborative translational research, testing, or develop of emerging discoveries in life sciences. </li></ul><ul><ul><li>Category III A (commercialization services): Provides funding for specific business services to the entrepreneurial community involved in life sciences commercialization. </li></ul></ul><ul><ul><ul><li>Eligible applicants include universities and businesses. </li></ul></ul></ul><ul><ul><ul><li>Aimed at supporting unique business growth, attraction, and develop services that are specific to the life sciences sector. </li></ul></ul></ul>
  5. 5. MTTC FUND RFP <ul><li>Funding Categories (cont’d) </li></ul><ul><ul><li>Category III B (commercialization investment program): Provides funding to companies positioned to commercialize products or services in the life sciences area. </li></ul></ul><ul><ul><ul><li>Eligible applicants are companies only. </li></ul></ul></ul><ul><ul><ul><li>Funds to provide a competitive advantage for Michigan companies by providing an investment that aims to catalyze market penetration efforts and progress toward long-term sustainable growth. </li></ul></ul></ul>
  6. 6. MTTC FUND RFP <ul><li>Program Timeline </li></ul>Contract negotiations Jun. 15 - Sep. 15, 2005 Steering Committee meeting (award decisions) Jun. 14, 2005 Final funding recommendations received Jun. 3, 2005 Independent mail review of full proposals including the interview process and final report submitted to MEDC Mar. 18 - Jun. 3, 2005 Full proposal submission due date Mar. 9, 2005 Invitation to full proposal Feb. 3, 2005 Independent peer-review of pre-proposals Nov. 29, 2004 - Jan. 21, 2005 Pre-proposal submission due date Nov. 17, 2004
  7. 7. MTTC FUND RFP <ul><li>Eligibility </li></ul><ul><li>As a “nonprofit research institution in Michigan” or as a “private research facility in Michigan,” the PI for the project must be a full-time employee of an organization whose core activity is research and/or development. The principal site for the project is MI, and the facility must be owned by the applicant or by a project collaborator. </li></ul><ul><li>As a “Michigan-based for-profit company,” the PI must be a full-time employee of a for-profit company who will be located primarily for the duration of the project at the principal site at which the project will be conducted. The company must have a major share of business activity in Michigan. Majority of economic benefits must accrue within MI. </li></ul>
  8. 8. MTTC FUND RFP <ul><li>Eligibility (cont’d) </li></ul><ul><li>Previous years’ MLSC or MTTC fund awardees are eligible but must provide a detailed update of their program accomplishments to date in the new application </li></ul><ul><li>If additional funds for the same project are sought applicant must demonstrate significant progress on project </li></ul><ul><li>Eligibility is determined at the time of award, i.e., can apply from out-of-state if plan to move to MI at time of award. </li></ul>
  9. 9. MTTC FUND RFP <ul><li>Collaboration </li></ul><ul><li>Category I (basic research fund), Category III (commercialization development fund): Collaboration is highly encouraged. </li></ul><ul><li>Category II (applied research fund): Must include high-value collaboration between the eligible applicant and the collaborating entity. </li></ul><ul><li>Must document prior or planned genuine productive collaboration such as: commitment of resources (e.g., time, money, facilities, equipment, intellectual property) or performance of specific aims. </li></ul>
  10. 10. MTTC FUND RFP <ul><li>Qualifying Research Fields </li></ul><ul><li>Qualifying life sciences fields include pharmaceuticals, medical devices, instrumentation, diagnostics, biotechnology, and research and ancillary services. </li></ul><ul><li>Proposals may employ various biological models and organisms. </li></ul><ul><li>Proposals can have cross-over applications to advanced automotive and homeland security sectors including sensors and measurement devices, biosensing, antitoxins, food and water safety and security, and surveillance/detection. </li></ul>
  11. 11. MTTC FUND RFP <ul><li>Qualifying Research Fields ( cont’d ) </li></ul><ul><li>May include technology such as microsystems, MEMs, nanotechnology, and information technology. </li></ul><ul><li>MAY NOT include proposals for education, training of personnel, curriculum development, or projects that address health care delivery, public health, epidemiology, natural resources management, agriculture, or ecology. </li></ul>
  12. 12. MTTC FUND RFP <ul><li>Organizational Contributions/Match </li></ul><ul><li>Each of the participating organizations must provide a specific contribution to the project. </li></ul><ul><ul><li>For example: use of personnel, space, facilities; indirect cost sharing. </li></ul></ul><ul><li>Each proposal must include a cash match </li></ul><ul><ul><li>For non-profits any source can provide the cash match </li></ul></ul><ul><ul><li>For profits must supply a cash match from a qualified investor </li></ul></ul><ul><li>• III A proposal must get some of the cash from the recipients of the services they provide </li></ul>
  13. 13. MTTC FUND RFP <ul><li>Review Process </li></ul><ul><li>Phase I: Pre-proposal submission and competitive review by independent peer review agency. </li></ul><ul><li>Phase II: Selected pre-proposal applicants will be invited to submit full proposals which will undergo competitive peer review. </li></ul><ul><li>Phase III: Selected full proposal applicants will be invited for an interview conducted by the independent peer-review agency (expert peer panel). </li></ul><ul><li>Final funding decisions to be made by the Steering Committee based upon the Phase III competition. </li></ul>
  14. 14. MTTC FUND RFP <ul><li>Award Type and Terms of Award </li></ul><ul><li>$26.5 million available for the MTTC competition. </li></ul><ul><li>No specific funding request limitations. </li></ul><ul><li>Funding for up to three years. </li></ul><ul><li>Grant awards available to applicants from Michigan universities and Michigan not-for-profit research institutes. </li></ul><ul><li>Awards given to for-profit organizations will be in the form of a loan or an equity investment. </li></ul><ul><li>Indirect cost rate: 20% (excluding equipment, patient care cost, consultant/consortium cost, subcontracts, building alternations and renovations.) </li></ul>
  15. 15. MTTC FUND RFP <ul><li>Pre-Proposal Submission </li></ul><ul><li>Pre-proposal application system can be accessed at: </li></ul><ul><li>Application includes ten steps: </li></ul><ul><ul><li>Project information </li></ul></ul><ul><ul><li>Project director information </li></ul></ul><ul><ul><li>Budget information </li></ul></ul><ul><ul><li>Applicant organization information </li></ul></ul><ul><ul><li>Authorized representative information </li></ul></ul><ul><ul><li>Executive summary (250 word limit) </li></ul></ul><ul><ul><li>Comments </li></ul></ul><ul><ul><li>Key Personnel for applicant organization </li></ul></ul><ul><ul><li>Collaborating organization(s) information </li></ul></ul><ul><ul><li>Submission of PDF file (Pre-proposal and biographical sketches) </li></ul></ul>
  16. 16. MTTC FUND RFP <ul><li>Basic Research Fund Proposal Review Criteria and Weighting </li></ul>10% Quality of intellectual property plan 20% Quality of project match and potential of project to leverage additional resources 20% Team qualifications/quality of collaborative efforts/expertise of collaborative team and organizational commitments 15% Economic impact on Michigan 15% Feasibility of proposed work with time/funds available 20% Scientific and technical quality of proposed research Weighting Criterion
  17. 17. MTTC FUND RFP <ul><li>Applied Research Fund Proposal Review Criteria and Weighting </li></ul>10% Quality of intellectual property plan 15% Quality of project match and potential of project to leverage resources 10% Team qualifications/quality of collaborative efforts/expertise of collaborative team 15% Economic impact on Michigan 30% Articulation of path to market, market potential, and quality of marketing plan 20% Research concept quality, application focus, and commercial contribution Weighting Criterion
  18. 18. MTTC FUND RFP <ul><li>Commercialization Services Program Review Criteria and Weighting </li></ul>15% Identification of future uses/users/fee structure and intellectual property plans (where applicable) 15% Leveraging/matching funds 20% Implementation and administrative plan 20% Organizational expertise and available resources 30% Quality, uniqueness, and importance of commercialization service Weighting Criterion
  19. 19. MTTC FUND RFP <ul><li>Commercialization Investment Proposal Review Criteria and Weighting </li></ul>5% Quality of intellectual property plan 10% Leverage/matching funds 20% Management team experience and expertise 15% Economic impact on Michigan 15% Market analysis/competitiveness of proposed commercialization opportunity 15% Commercialization feasibility with available time/funds/facilities/resources 20% Quality and importance of commercialization opportunity Weighting Criterion
  20. 20. Things to Remember When Submitting Pre-Proposals: <ul><li>Online submissions only </li></ul><ul><li>No PAF required but send copy of submission to Anna Schork or Elaine Brock at DRDA </li></ul><ul><li>No change in subject matter is allowed from pre-proposal to full proposal </li></ul><ul><li>Science limited to 250 word Executive Summary </li></ul><ul><li>Criteria by category apply to pre-proposals and full proposals </li></ul>
  21. 21. Things to Remember About Pre-Proposals (cont’d): <ul><li>2 page Biosketches required on Form MTTC-01 (include patents and licenses) </li></ul><ul><li>Budget required </li></ul><ul><li>Applicant Organization is “The Regents of the University of Michigan” </li></ul><ul><li>Authorized Rep is “ Elaine L. Brock” </li></ul><ul><li>DUNS # 0731331571 </li></ul><ul><li>Cash Match required for all proposals </li></ul>
  22. 22. Things to Remember About Full Proposals Generally: <ul><li>On-line submission only. The system slows as more submitters are on it. Don’t wait till 4:55 on March 9th. </li></ul><ul><li>Follow the outline exactly. </li></ul><ul><li>Project Plan limited to 20 pages. No appendix material accepted. </li></ul><ul><li>Request letters of commitment/support via online system, i.e., you submit name to MEDC system. MEDC requests letter. Letter is submitted to MEDC online by proposal deadline. </li></ul>
  23. 23. Things to Remember About Full Proposals (cont’d): <ul><li>• Separate forms for Total (01), MTTC funds requested (02), and Matching funds (03) </li></ul><ul><li>• Budget forms are self-calculating . Matching funds are subtracted from total costs so apparently you should not try to quantify in-kind contributions. </li></ul><ul><li>• Budget justifications have no page limits so could include in-kind contributions there and/or under personnel and facilities sections. </li></ul>
  24. 24. Things to Remember About Full Proposals (cont’d): <ul><li>Collaborators must fill out 04 budget form if they are getting MTTC $$ and 05 form if they are not. </li></ul><ul><li>For-profit companies must secure a cash match from a qualified investor. </li></ul><ul><li>Need separate forms for each year of the project for each collaborator </li></ul><ul><li>These forms have had some weird glitches in the past so start working on them well in advance of deadline </li></ul>
  25. 25. Things to Remember About Full Proposals (cont’d): <ul><li>All proposals require an Intellectual Property Plan or and explanation of why there are no IP issues involved in the project. </li></ul><ul><li>The IP Plan must be specifically developed for the project, i.e., can’t use the templates from previous years. </li></ul><ul><li>Contact your DRDA PR or OTT Licensing Rep for help. Start this part early! </li></ul>
  26. 26. Things to Remember About Full Proposals (cont’d): <ul><li>All proposals require disclosure of significant financial interests by applicant organization and each collaborating organization: </li></ul><ul><ul><li>Salary and other payment for services </li></ul></ul><ul><ul><li>Equity interests </li></ul></ul><ul><ul><li>Intellectual property rights, royalties </li></ul></ul><ul><ul><li>Other contractual arrangements </li></ul></ul>
  27. 27. Things to Remember About Full Proposals Category I: <ul><li>Science gets only 20% of the consideration. </li></ul><ul><li>Quality of the team also is 20%. Commercial partners preferred. </li></ul><ul><li>Showing ability to match or leverage other funding is essential. Each participant must show contribution of specific new resources. </li></ul>
  28. 28. Things to Remember About Full Proposals Category II: <ul><li>Focus on translating research findings to commercial applications. </li></ul><ul><li>Collaboration is required - at least 2 institutions or organizations. Commercial partners preferred. </li></ul><ul><li>Each participant must show contribution of specific new resources. </li></ul>
  29. 29. Things to Remember About Full Proposals Category III A: <ul><li>Focus on building a commercialization support system. Preference for proposals that offer unique, specialized services to the MTTC business community. </li></ul><ul><li>Match or fee for service structure required. </li></ul><ul><li>Describe how service will be self-supporting after MTTC funding. </li></ul>
  30. 30. Things to Remember About Full Proposals Category III B: <ul><li>UM is not eligible to apply directly but can participate on companies’ proposals. </li></ul><ul><li>Focus on commercialization of a product. </li></ul><ul><li>Awards in the form of loans or equity investments. </li></ul><ul><li>10 page proposal plus 20 page business plan required. </li></ul>
  31. 31. To Get Help With: <ul><li>RFP Details: </li></ul><ul><ul><li>DRDA will establish an email list and provide updates, tips, advice. Email to [email_address] to get on or off list. We’ll start with MLSCF Awardees list. Please check UM Directory to see if you’re on it before messaging Pat. </li></ul></ul><ul><ul><li>MTTC will have a FAQ site and help desk. </li></ul></ul><ul><ul><li>DRDA - </li></ul></ul><ul><ul><li>Anna Schork, [email_address] , 935-1356 </li></ul></ul><ul><ul><li>Elaine Brock, [email_address] , 763-7188 </li></ul></ul><ul><ul><li>Pat Roe, [email_address] , 936-1289 </li></ul></ul>
  32. 32. To Get Help With: <ul><li>COI Disclosures: </li></ul><ul><ul><li>DRDA - </li></ul></ul><ul><ul><li>Anna Schork, [email_address] , 935-1356 </li></ul></ul><ul><ul><li>Elaine Brock, [email_address] , 763-7188 </li></ul></ul><ul><ul><li>Med School - </li></ul></ul><ul><ul><li>Valerie Rup, [email_address] , 936-1971 </li></ul></ul><ul><ul><li>Outside the Med School - </li></ul></ul><ul><ul><li>Judy Nowack, [email_address] , 763-1289 </li></ul></ul><ul><ul><li>Lynn Cook, [email_address] , 647-7768 </li></ul></ul>
  33. 33. To Get Help With: <ul><li>IP Plans: </li></ul><ul><ul><li>DRDA - </li></ul></ul><ul><ul><li>Anna Schork, [email_address] , 936-1356, </li></ul></ul><ul><ul><li>Elaine Brock, [email_address] , 763-7188, </li></ul></ul><ul><ul><li>Tom Zdeba, [email_address] , 936-1292 </li></ul></ul><ul><ul><li>OTT - </li></ul></ul><ul><ul><li>Robin Rasor, [email_address] , 615-8433 </li></ul></ul>