In individuals with ventricular arrhythmias, used to suppress arrhythmias. Antiarrhythmic agents may be considered the first-line therapy in the prevention of sudden death in certain forms of structural heart disease
Refers to a cardiac muscle cell firing off an impulse on its own
All cardiac cells can initiate an action potential , however, only some of these cells are designed to routinely trigger heart beats
Found in the 'conduction system' of the heart and include the SA node, AV node, Bundle of HIS and Purkinje fibers
S inoatrial node is a single specialized location in the atrium which has a higher automaticity (a faster pacemaker) than the rest of the heart, and therefore is usually responsible for setting the heart rate, and initiating each heart beat.
Usually go away within a few hours to a day or so and are not said to be permanent once the medication has "washed out" of the system
Common side effects of these drugs include constipation, dizziness, and weakness
Swelling of the feet and ankles
Excessive lowering of the blood pressure
Most common with first dose
Change position slowly
Rarely an excessively slow heart beat
Worsening of HF
Many calcium channel blockers come in an extended release or sustained release preparation ( XL, SR) that is convenient for once a day dosing. These tablets should not be cut in half or crushed, as this would affect the rate of drug release into the bloodstream.