REQUEST # 67644                      Anti-Adherence to Skin and Hard Surfaces RESPONSE DUE DATE: December 9, 2011 MANAGER:...
NineSigma Request #67644           Anti-Adherence to Skin and Hard Surfaces                              Page 2Similar tre...
NineSigma Request #67644                  Anti-Adherence to Skin and Hard Surfaces                       Page 3RESPONDING ...
Upcoming SlideShare
Loading in …5
×

Anti adherence to skin and hard surfaces

1,072 views

Published on

Published in: Health & Medicine, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
1,072
On SlideShare
0
From Embeds
0
Number of Embeds
601
Actions
Shares
0
Downloads
1
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Anti adherence to skin and hard surfaces

  1. 1. REQUEST # 67644 Anti-Adherence to Skin and Hard Surfaces RESPONSE DUE DATE: December 9, 2011 MANAGER: Jack Lienesch SOLUTION PROVIDER HELP DESK EMAIL: PhD@ninesigma.com PHONE: +1-216-283-3901 Opportunity Licensing, product acquisition, contract research, proof of (click buttons above) concept leading to scale-up to manufacturing, joint development, supplier agreement, etc. Timeline Phase 1 – 12 months for proof of concept in a laboratory Phase 2 – Commercial development to be determined Financials Phase 1 – Laboratory proof of concept funding up to US$ 100,000 Phase 2 – To be negotiatedREQUEST FOR PROPOSAL DESCRIPTION  Novel surface treatments that repel proteins, bacteria, and dirt/grimeNineSigma, representing a Fortune 500  Durable anti-adherent treatments that canconsumer products company, seeks proposals resist abrasionfor the development of technologies that preventthe adhesion of biological materials onto surfaces Technology solutions that are of short-term(either hard surfaces or skin, ideally both). Of duration (i.e., would last a few hours up to eightparticular interest are partners with technology hours and possibly up to a day) would be ideal.solutions that are ready to commercialize orcould be readied for commercialization within 1-2 BACKGROUNDyears. Current cleaning approaches are designed toExamples of novel approaches of interest would remove contamination (dirt, bacteria, stains) onceinclude: they have attached onto a surface. There are  Anti-adherence formulations for hands, few examples of any treatments or materials that skin, and mucus tissues are designed to keep a surface clean after they  Anti-adherent formulations for hard have been applied, such that the surface surfaces including metal, plastic and becomes resistant to future adherence and natural materials contamination. Typical approaches to this are to  Anti-adherent compositions that can be change the surface hydrophobicity such that the easily applied to skin or hard surfaces water contact angle is substantially increased using either wipe or spray techniques (making the surface water-repellent). While this  Compositions must have acceptable type of surface treatment is readily applied to aesthetic and safety profiles hard non-porous surfaces, it cannot be extended to skin. Offices: Cleveland - USA, Tokyo - Japan, Leuven - Belgium www.ninesigma.com RFP format and graphics© Copyright 2011 NineSigma, Inc
  2. 2. NineSigma Request #67644 Anti-Adherence to Skin and Hard Surfaces Page 2Similar treatments for skin are virtually non-existent. Our client sees this as a uniqueopportunity to develop a skin-friendly technology APPROACHES NOT OF INTERESTthat would provide a barrier to adherence ofbacteria, proteinacious materials, as well as dirtand grime. Such skin products would have broad  Technologies that are based on biocidal orapplicability in both the consumer and healthcare biostatic action.markets.  Incremental variations on fluorocarbon surface treatmentsPOSSIBLE APPROACHES  Technology solutions without patent protection (IP must already be issued orExamples of applications of interest for filed)NineSigma’s client would include the following(note, your technology does not necessarily needto address one of these specific examples): ANTICIPATED PROJECT PHASES OR PROJECT PLAN  It is expected that the compositions or Phase 1 – Proof of concept in our client’s formulations will provide for the reduction of laboratory attachment of bacteria, fungi, and viruses Phase 2 – Commercial development to be by at least 99% for a period of up to 8 determined hours.  It is expected that the compositions or CRITERIA FOR MOVING FROM PHASE 1 TO PHASE 2 formulations will provide for the reduction of attachment of organic soil by at least 99% for a period of up to 8 hours. Demonstrate in our client’s laboratory that the  Hydrophilic materials that are dermal anti- proposed approach meets all the requirements adherents.  Hydrophobic and hydrophilic combinations APPROPRIATE RESPONSES TO THIS REQUEST that are hard surface anti-adherents  Competitive displacement compositions for Responses from companies (small to large), both microbes and organic soil academic researchers, other research institutes,  Compositions that are naturally-derived consultants, venture capitalists, entrepreneurs, or  Compositions that can be used over a wide inventors are welcome. range of surfaces both animate and inanimate. I am a company or academic person with  Compositions that reduce inorganic technology which should provide a solution ready depositions to hard surfaces for testing and transfer to commercial use.  Compositions that reduce adherence of biological fluids, blood, sputum, urine, I am a company or academic person with feces, complex polysaccharides to skin and technology which should provide a solution but mucosal tissue. that requires further research and development to ready it for transfer to commercial use.  Compositions that reduce attachment of infectious microbes, filamentous fungi, yeast, fungal spores, bacterial spores, Gram negative bacteria, Gram positive bacteria, enveloped viruses, non-enveloped viruses to skin and mucosal tissue.  Compositions that use Quorum sensing control Offices: Cleveland - USA, Tokyo - Japan, Leuven - Belgium www.ninesigma.com
  3. 3. NineSigma Request #67644 Anti-Adherence to Skin and Hard Surfaces Page 3RESPONDING TO THIS REQUEST NON-CONFIDENTIAL DISCLOSURE By submitting a Response you represent that the Response does not and will not be deemed to contain any confidential information of any kind whatsoever. Your Response should be an executive summary (about 3 pages). The Response should briefly describe the technical approach and provide information on technology performance, background, and description of the responding team and their related experience. By submitting a Response, you acknowledge that NineSigma’s client reserves the sole and absolute right and discretion to select for award all, some, or none of the Responses received for this announcement. NineSigma’s client also may choose to select only specific tasks within a proposal for award. NineSigmas client has the sole and absolute discretion to determine all award amounts. RESPONSE EVALUATION NineSigma’s client will evaluate the Response using the following criteria:  Overall scientific and technical merit of the proposed approach  Approach to proof of concept or performance  Potential for proprietary position (i.e., is the technology novel or protectable)  Economic potential of concept  Respondent’s capabilities and related experience  Realism of the proposed plan and cost estimates The client will contact respondents with highly responsive proposals for next steps. Offices: Cleveland - USA, Tokyo - Japan, Leuven - Belgium www.ninesigma.com

×