Corporate overview
<ul><li>As a contract research company which supports its customers'  drug discovery  activities, </li></ul><ul><li>Idealp...
<ul><li>Key figures </li></ul><ul><li>Founded in 2000 by Serge Petit </li></ul><ul><li>1500 square meters of labs </li></u...
<ul><ul><ul><li>Contract research in medicinal Chemistry </li></ul></ul></ul><ul><ul><ul><li>FTE based flexible contract r...
<ul><ul><ul><li>Contract Research in chemistry </li></ul></ul></ul><ul><ul><ul><li>FTE based flexible contract chemistry r...
<ul><ul><ul><li>Custom synthesis </li></ul></ul></ul><ul><ul><ul><li>Fee for service based  </li></ul></ul></ul><ul><ul><u...
<ul><li>For synthetic chemistry: Radleys Carousel reaction stations Quest 205 Argonaut Microwave apparatus  Variomag react...
<ul><ul><ul><li>In vitro  early ADMET   </li></ul></ul></ul><ul><ul><ul><li>Physicochemical properties </li></ul></ul></ul...
<ul><li>Key project management steps </li></ul><ul><li>Signature of a confidentiality agreement </li></ul><ul><li>First me...
<ul><li>Idealp-Pharma’s values </li></ul><ul><li>High-quality work which meets your needs  </li></ul><ul><li>Meeting your ...
<ul><li>Contact </li></ul><ul><li>Mehdi Chelbi </li></ul><ul><li>Business Development Manager </li></ul><ul><li>Idealp-Pha...
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Idealp Pharma Corporate Overview Jan 2010 Str

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Idealp Pharma Corporate Overview Jan 2010 Str

  1. 1. Corporate overview
  2. 2. <ul><li>As a contract research company which supports its customers' drug discovery activities, </li></ul><ul><li>Idealp-Pharma provides a range of flexible services : </li></ul><ul><ul><ul><li>contract research in medicinal chemistry </li></ul></ul></ul><ul><ul><ul><li>contract research chemistry </li></ul></ul></ul><ul><ul><ul><li>custom synthesis </li></ul></ul></ul>- - Idealp-Pharma mission statement
  3. 3. <ul><li>Key figures </li></ul><ul><li>Founded in 2000 by Serge Petit </li></ul><ul><li>1500 square meters of labs </li></ul><ul><li>30 staff </li></ul><ul><li>10 years of collaboration with pharma & biotechs </li></ul>- - Idealp-Pharma at a glance
  4. 4. <ul><ul><ul><li>Contract research in medicinal Chemistry </li></ul></ul></ul><ul><ul><ul><li>FTE based flexible contract research </li></ul></ul></ul><ul><ul><ul><li>Experienced medicinal chemistry team </li></ul></ul></ul><ul><ul><ul><li>Focused library synthesis </li></ul></ul></ul><ul><ul><ul><li>Develop SAR </li></ul></ul></ul><ul><ul><ul><li>Biological screening analysis cycles </li></ul></ul></ul><ul><ul><ul><li>ADME/Tox properties analyses </li></ul></ul></ul><ul><ul><ul><li>Speed up the hit optimisation process </li></ul></ul></ul><ul><ul><ul><li>Identify lead compounds with desired activity and physical properties </li></ul></ul></ul>Medicinal Chemistry
  5. 5. <ul><ul><ul><li>Contract Research in chemistry </li></ul></ul></ul><ul><ul><ul><li>FTE based flexible contract chemistry research </li></ul></ul></ul><ul><ul><ul><li>Novel molecule synthesis contract projects </li></ul></ul></ul><ul><ul><ul><li>Particular expertise in multi-step synthesis </li></ul></ul></ul><ul><ul><ul><li>Design and synthesis of high quality small to medium sized libraries. </li></ul></ul></ul><ul><ul><ul><li>Patent exemplification </li></ul></ul></ul><ul><ul><ul><li>Expend and develop your SAR in an efficient and reliable manner </li></ul></ul></ul><ul><ul><ul><li>Flexible management of molecule optimisation projects </li></ul></ul></ul><ul><ul><ul><li>Clients may refocus their project at any time </li></ul></ul></ul>Chemistry
  6. 6. <ul><ul><ul><li>Custom synthesis </li></ul></ul></ul><ul><ul><ul><li>Fee for service based </li></ul></ul></ul><ul><ul><ul><li>Customer's need for a particular compound </li></ul></ul></ul><ul><ul><ul><li>Up to the 500 gram scale </li></ul></ul></ul><ul><ul><ul><li>Customer may wish to supply a known route </li></ul></ul></ul><ul><ul><ul><li>Knowledge to devise or improve synthetic routes </li></ul></ul></ul><ul><ul><ul><li>IP assumes full responsibility for delivering your molecules </li></ul></ul></ul>Custom synthesis
  7. 7. <ul><li>For synthetic chemistry: Radleys Carousel reaction stations Quest 205 Argonaut Microwave apparatus Variomag reaction blocks Genevac HT4 evaporating system </li></ul>Chemistry Capabilities For purification : Flash chromatography Automated systems : - Biotage - Combiflash Isco System Gilson-Thermo Quest AQA semi-preparative LC-MS For analytical chemistry : LC-MS: Agilent and Gilson-Thermo Quest AQA Bruker NMR spectrometers: AC 200, ALS 300, DRX 300 and DRX 500. Mass spectrometers: Nermag R10-10H and Thermo Quest MAT 95XL IR:  Nicolet FTIR
  8. 8. <ul><ul><ul><li>In vitro early ADMET </li></ul></ul></ul><ul><ul><ul><li>Physicochemical properties </li></ul></ul></ul><ul><ul><ul><li>Permeability assays (PAMPA) </li></ul></ul></ul><ul><ul><ul><li>Metabolic and plasmatic stability on human and murine microsomes </li></ul></ul></ul><ul><ul><ul><li>CYP450 inhibition  </li></ul></ul></ul><ul><ul><ul><li>Cytotoxicity tests (MTT, ATP and LDH release tests) </li></ul></ul></ul><ul><ul><ul><li>Cardiotoxicity (hERG Chanel assay on 384 well plates) </li></ul></ul></ul><ul><ul><ul><li>Exploratory PK and Toxicity </li></ul></ul></ul><ul><ul><ul><li>Management of in vivo PK and toxicity studies </li></ul></ul></ul>ADMET Capabilities
  9. 9. <ul><li>Key project management steps </li></ul><ul><li>Signature of a confidentiality agreement </li></ul><ul><li>First meeting with focused discussion between the partners </li></ul><ul><li>Rapid project proposal and pricing from our team  </li></ul><ul><li>Terms agreed, followed by contract drafting </li></ul><ul><li>Selection of a dedicated PhD-level project manager and the project team </li></ul><ul><li>Scheduled project meetings/reports and/or on request: face-to-face and/or phone meetings, encrypted e-mail… </li></ul><ul><li>Final report and product delivery </li></ul>Work practices
  10. 10. <ul><li>Idealp-Pharma’s values </li></ul><ul><li>High-quality work which meets your needs </li></ul><ul><li>Meeting your deadlines </li></ul><ul><li>Responsiveness and flexibility </li></ul><ul><li>Transparency </li></ul><ul><li>Rigorous procedures for data management, backup and security </li></ul>Work practices
  11. 11. <ul><li>Contact </li></ul><ul><li>Mehdi Chelbi </li></ul><ul><li>Business Development Manager </li></ul><ul><li>Idealp-Pharma </li></ul><ul><li>Bâtiment CEI </li></ul><ul><li>66,  Bd Niels Bohr - BP 52132 </li></ul><ul><li>69603 Villeurbanne - France </li></ul><ul><li>Tel : +33 437 488 795 </li></ul><ul><li>Mob : +33 663 878 861 </li></ul><ul><li>E-mail : m.chelbi@idealp.com </li></ul><ul><li>www.idealp-pharma.com </li></ul>www.idealp-pharma.com Thanks for your attention
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