Planning for INBRE II – The Renewal
External Advisory Board Meeting
12-13 February 2009
Renewal - Strengths
• INBRE-I has initiated a network linking the three main partners
(UNR, UNLV, NVCI).
• The Biomedical Pipeline functions smoothly and is enormously
• Research service cores.
• The Administrative Core has a good understanding of how to
manage the INBRE.
• Interactions with COBRE projects are increasing.
• Mentoring and faculty development is improving.
Renewal - Challenges
• The state lacks a strategic plan for biomedical sciences.
• The new biomedical institutions are private and developing bilateral
partnerships: NVCI, Rouvo Brain Institute, Whittemore-Peterson
Institute, Touro University College of Osteopathic Medicine
(Nevada’s largest medical school). Where does INBRE fit in?
• Many of the “senior administrators” at UNR, UNSOM, and UNLV are
new and interim
• The state’s fiscal situation is dire
• Much action and growth in the south (UNLV, NVCI, Rouvo, Touro)
Renewal - Opportunities
• This is the time to change programs that are less rewarding
– Basic Science Research
• We have a medical school
– Clinical faculty as researchers and collaborators
– MD / PhD
– Resident research experience
– Fellowship programs
• We have untapped areas
– NIH Science Education Partnership Awards (SEPA)
Renewal - Opportunities
• We have untapped partners (if I can figure out how to work with
– Development of research at TMCC, CSN, GBC
– CTSA at UC Davis
– UNR College of Agriculture, Biotechnology and Natural
– Nevada State College
– Rouvo Brain Institute
– Whittemore-Peterson Institute
– Touro University College of Osteopathic Medicine
Draft Renewal – Biomedical Students Pipeline
• Expand INBRE undergraduate outreach and create K-12 program.
– We are partnering with TMCC to embed research in community
colleges. (Curriculum development)
– We are partnering with Dr. Julie Ellsworth to submit a SEPA
award spring 2009. In year 5 we are piloting 4 middle school
Basic Science Pipeline Current Proposed
Undergrad summer research (UROP)
program at UNR, UNLV, NVCI $78,000 $78,000
Biomedical Students Pipeline $218,000 $228,900
Research at Community Colleges $0 ?
K-12 Science Coaches $10,000 $32,000
Community College Research
• The goal is enhanced biomedical science instruction and experience
at community colleges.
– Incorporate “Real Science” into existing biology, chemistry, and
• Developed following a workshop in Seattle presented by the Council
for Undergraduate Research
Dr. Julie Ellsworth, Dr. Dan Lorenz, Dr. Laura Briggs, TMCC
Dr. James Kenyon, INBRE
• Ideas presented to Dr. Jowel Laguerre VP for Academic Affairs at
• Partership with Chris Fritsen (NV NASA Space Grant Consortium
• K-5 Level (Elementary School) – The “Music Teacher” Model
– Teachers with previous training in science to be roving teachers
for science at multiple elementary schools.
– Renovate existing school space to provide bench and storage
• 6th-8th Grades (Middle School) and 9th-12th (High School) – Science
– Out-of-classroom Science Coaches (paid like athletic coaches)
who will run science clubs and mentor students working on
science fair projects.
Draft Renewal - Cores
• Continue current support of research service cores.
Cores Current Proposed
Bioinformatics North $253,000 $240,000
Bioinformatics South $85,000 $60,000
Proteomics $262,000 $260,000
Cytometry $25,000 $25,000
Live Animal Imaging - -
UNLV Central Core $170,000 $200,000
Draft Renewal – Faculty Research Projects
• Fund one early career basic scientist at each partner
institution. New hires at UNR and UNLV.
Basic Science Faculty Current Proposed
UNR $351,000 $125,000
UNLV $216,000 $125,000
NVCI $243,000 $125,000
Draft Renewal – Develop Clinical Pipeline
• Create new Clinical Pipeline with funds previously directed to
Clinical Pipeline Current Proposed
MD/PhD Stipends $0 $60,000
Residents (Yr 5 pilot program) $50,000 $50,000
Clinical Faculty (Yr 5 pilot program) $30,000 $150,000
• MD/PhD – The PI is working with the UNSOM Senior Associate
Dean for Research to provide stipends for two MD / PhD students to
work in outstanding (funded) basic science labs in Nevada.
• Resident Research Experience – The PI is working with the
UNSOM Associate Dean for Graduate Medical Education to develop
a program that will put Nevada Residents into outstanding (funded)
basic science labs in Nevada. The current plan is for a 3 month
• Clinical Faculty Research – The PI is working with the Dean of the
School of Medicine and Vice President of the Division of Health
Sciences to develop an RFA for a clinical / translational science
project. The goal is to enable a clinical faculty member of UNSOM to
initiate a project that will ultimately be funded independently.
Clinical Pipeline – Pilot Programs in Year 5
• $50K for resident research experience
• $30K for a genome-wide association study using single nucleotide
– Dr. Karen Schlauch and the INBRE Administrative Core put out an RFA
circulated to the partner institutions and the School of Medicine for a preliminary,
proof-of-concept project that will lead to a comprehensive experimental study
fundable by the NIH.
Draft Renewal - Community Based
Participatory Research Core (CBPR)
• We are investigating the possibility of a new Community Based
Participatory Research Core.
– Increase INBRE activity in clinical / translational
– Engage faculty and programs in UNLV School of Public Health,
UNR Division of Health Sciences, Touro University College of
CBPR $0 $100,000