Assignment Name: Unit 3 Discussion Board
Deliverable Length: 3-4 paragraphs
Details: Biotechnology allows us to use living organisms or their processes
for human needs or purposes. Currently, this topic includes such
general examples as cloning, stem cells (adult, umbilical cord, and
embryonic), DNA fingerprinting, biological warfare, bioremediation,
genetically modified organisms, vaccines, and transgenic plants and
animals to name a few.
Research how a SPECIFIC biotechnology application within the
above GENERAL examples (or ones not listed above) is used
today. Example: Insulin production in bacteria is an example under
the general topic of recombinant organisms.
What specific biotechnology application did you choose?
Briefly describe this biotechnology application.
Based upon the definition of biotechnology, describe how
your biotechnology application is an example of
What benefits are derived from this application?
Are there any concerns or negative impacts associated with
this use of biotechnology? Why or why not?
Important please read! Each person in the class should choose a
DIFFERENT biotechnology application. Read other students'
posts to see what they have selectedbefore posting.
This assignment will be assessed using the rubric provided here.
This assignment will also be assessed using additional criteria
In your own words, please post a response to the Discussion
Board and comment on other postings. You will be graded on
the quality of your postings.
For assistance with your assignment, please use your text, Web
resources, and all course materials. Please refer to the following.
External Web links:
Unit 3: Biotech
Unit 3: Excellence Through Stewardship
Assignment Name: Unit 3 Individual Project
Deliverable Length: Punnett Square & answers to all questions Part 1, 2, & 3
Details: Complete all three parts and answer all questions.
Download Graphic Organizer for answering all questions in this assignment.
Part I: Genetics – From Genes to Proteins, Mutations (Chapter 10)
Overview: Genetic information in DNA is transcribed to RNA and then
translated into the amino acid sequence of a Protein.
A) Step 1 - Transcription: During the process of transcription, the
information in the DNA codons of a gene is transcribed into RNA.
Suppose that gene X has the DNA base sequence 3’-
Question: What would be the base sequence of RNA after transcription
occurs? (In this particular example, assume that the RNA product does not
require processing to become mRNA. In other words, the transcribed RNA
becomes the mRNA sequence.)
Place your answer in the Graphic Organizer.
B) Step 2 - Translation: During protein synthesis at the ribosome, the base
sequence of the mRNA codons is translated to the amino acid sequence of a
Question: Using the mRNA that you just transcribed, use the genetic code
table to determine the resulting amino acid sequence. Place your answer in
the graphic organizer.
Also submit the answer to these questions, using the Graphic
What is the significance of the first and last codons?
What meaning do these codons have for protein synthesis?
C) Mutations: A mutation is defined as a change in the base sequence of
DNA. This may occur as a “mistake” in DNA replication, for example.
Suppose that during DNA replication, two mutant DNA sequences are
produced as shown following.
For the 2 mutated DNA sequences, you will investigate how these changes
might affect the sequence of amino acids in a protein.
Question: For each of the two, you will need to first transcribe the mRNA,
and then use the genetic code table to determine the amino acid sequence.
Submit these transcriptions and amino acid sequences as part of
your assignment in the Graphic Organizer.
In addition, state whether the protein sequence changes for each.
Also, explain why a change in amino acid sequence might affect
Here is the original sequence, followed by two mutated sequences, 1 and
Original sequence 3'- TACCCTTTAGTAGCCACT-5’
Mutated sequence 1) 3’-TACGCTTTAGTAGCCATT-5'
Mutated sequence 2) 3’-TAACCTTTACTAGGCACT-5’
Part II: Inheritance of Traits or Genetic Disorders (Chapter 12)
Bob and Sally recently married. Upon deciding to plan a family, both Sally
and Bob find out that they are both heterozygous for cystic fibrosis, but
neither of them has symptoms of the disorder.
Set up and complete a Punnett Square for cystic fibrosis for this couple,
adapting the Punnett Square in the Graphic Organizer as needed.
When doing the Punnett Square, C = normal allele; and c = allele for cystic
Based on the Punnett square, calculate chances (percentages) for the
for having a healthy child (not a carrier)
a child that is a carrier for the cystic fibrosis trait
a child with cystic fibrosis
Be sure to submit these percentages as part of your assignment.
Part III: Cell division, sexual reproduction and genetic variability
Eukaryotic cells can divide by mitosis or meiosis. In humans, mitosis
produces new cells for growth and repair; meiosis produces sex cells
(gametes) called sperm and eggs.
Although mutations are the ultimate source of genetic variability, both
meiosis and sexual reproduction also can contribute to new genetic
combinations in offspring.
Question: How do both meiosis and sexual reproduction (fertilization)
produce offspring that differ genetically from the parents? Be sure to talk
about steps in meiosis that increase variability as well as the process of
You will submit your Graphic Organizer with all answers.