New Investigators Committee
Update
Story Landis, Ph.D., Director, NINDS
Norka Ruiz Bravo, Ph.D., Deputy Director, OER
Dece...
First Major Independent ResearchFirst Major Independent Research
Support Occurs at an Ever-Later AgeSupport Occurs at an E...
R
2
= 0.71
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
1963 1967 1971 1975 1979 1983 1987 1991 1995 1999 2003
Established ...
NIH New Investigators CommitteeNIH New Investigators Committee
Committee Charge
 Develop a list of action items that have...
NIH New Investigators CommitteeNIH New Investigators Committee
Resources for discussion items:
NIH Postdoctoral Meeting Su...
Value of and need for:
 Consistent NIH definitions for “predocs,” “postdocs,” and
“new or first-time investigator”
 Proc...
NIH New Investigators CommitteeNIH New Investigators Committee
Discussion TopicsDiscussion Topics
Value of and need for:
...
New Career Transition ProgramNew Career Transition Program
The Committee recommends that NIH develop and
implement a stand...
Examples of Current IC Practices toExamples of Current IC Practices to
Foster New Investigator IndependenceFoster New Inve...
Where Are We Now?Where Are We Now?
 Dr. Zerhouni and IC Directors have agreed that
supporting New Investigators is a top ...
NIH New InvestigatorsNIH New Investigators
Pilot programs in place
 Compressing review cycles for new investigators
 New...
Summary of NIEHS ONES program
 R01 program intended for first-time R01 applicants.
 Individuals with faculty appointment...
Research IndependenceResearch Independence
NIH Is Committed to Providing a Bridge to
Research Independence for New Investi...
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Medical Research at the Crossroads: Forging the Path Together

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Medical Research at the Crossroads: Forging the Path Together

  1. 1. New Investigators Committee Update Story Landis, Ph.D., Director, NINDS Norka Ruiz Bravo, Ph.D., Deputy Director, OER December 1, 2005
  2. 2. First Major Independent ResearchFirst Major Independent Research Support Occurs at an Ever-Later AgeSupport Occurs at an Ever-Later Age For more information, see http://grants.nih.gov/grants/20040712_New_Investigator_Talk.ppt Average Age of Initial Type 1 R01/R23/R29 Award for Different Degrees Held 44 38 42 37 40 35 36 37 38 39 40 41 42 43 44 45 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 Fiscal Year Averageage M.D.-Ph.D. M.D. Ph.D.
  3. 3. R 2 = 0.71 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 1963 1967 1971 1975 1979 1983 1987 1991 1995 1999 2003 Established InvestigatorEstablished Investigator New InvestigatorNew Investigator Percentage of New Investigators in CompetingPercentage of New Investigators in Competing R01 Awards Continues to DecreaseR01 Awards Continues to Decrease FY 1962 - FY 2003
  4. 4. NIH New Investigators CommitteeNIH New Investigators Committee Committee Charge  Develop a list of action items that have the potential to:  Increase and maintain a healthy cohort of new and talented, NIH-supported, independent investigators.  Facilitate an investigator’s ability to receive their first R01 award earlier in their research career.
  5. 5. NIH New Investigators CommitteeNIH New Investigators Committee Resources for discussion items: NIH Postdoctoral Meeting Summary and Recommendations (2003) National Postdoctoral Association White Paper (2003) NRC Report, Bridges to Independence: Fostering the Independence of New Investigators in Biomedical Research (2005) NRC Report, Advancing the Nation’s Health Needs: NIH Research Training Programs (2005) The National Academies Guide, Enhancing the Postdoctoral Experience for Scientists and Engineers (2000)
  6. 6. Value of and need for:  Consistent NIH definitions for “predocs,” “postdocs,” and “new or first-time investigator”  Processes and systems to identify, enumerate, and track predocs and postdocs  NIH-recommended “best practices” for predoc and postdoc research training  Encouraging research institutions to offer postdoctoral scientists training in laboratory and project management, grant writing, and mentoring NIH New Investigators CommitteeNIH New Investigators Committee Discussion TopicsDiscussion Topics
  7. 7. NIH New Investigators CommitteeNIH New Investigators Committee Discussion TopicsDiscussion Topics Value of and need for:  Additional formalized training opportunities for non-U.S. citizens  Standardized career transition award program  Consistent and expanded use of IC-specific funding strategies
  8. 8. New Career Transition ProgramNew Career Transition Program The Committee recommends that NIH develop and implement a standardized career transition award program to promote the initiation of an independent research career. Career Transition Program:  Five years of support  Phase I provides 1-2 years of mentored support for advanced fellows  Phase II provides 3 years of independent research support contingent upon securing an independent research position and administrative review
  9. 9. Examples of Current IC Practices toExamples of Current IC Practices to Foster New Investigator IndependenceFoster New Investigator Independence  New Investigators receive special attention at Council as high program priority or equivalent.  Increased payline for scored R01 applications from New Investigators.  No imposed reductions in duration and amount of awards (beyond the recommendations of the initial review group) for New Investigators.  Fund applications to achieve a designated success rate rather than setting a specific payline for New Investigators applying for R01s.  R01 New Investigators whose applications score below the payline can submit 5-page letters responding to critiques in the summary statement for Advisory Council review. If these letters respond satisfactorily to the concerns raised by the study sections, the Council can decide to fund these applications, avoiding the need for resubmission. http://grants1.nih.gov/grants/new_investigators/index.htm
  10. 10. Where Are We Now?Where Are We Now?  Dr. Zerhouni and IC Directors have agreed that supporting New Investigators is a top priority  New Investigators Committee presented: − Preliminary recommendations to the IC Directors at the Budget Retreat in May − Final recommendations to the Steering Committee in November  Steering Committee is currently considering these recommendations
  11. 11. NIH New InvestigatorsNIH New Investigators Pilot programs in place  Compressing review cycles for new investigators  New independent investigator R01 program
  12. 12. Summary of NIEHS ONES program  R01 program intended for first-time R01 applicants.  Individuals with faculty appointments which are tenure track or equivalent and who have fewer than eight years of postdoctoral experience are eligible to apply.  Applicants are expected to devote at least 50% time and effort to the award.  Award can be up to 5 years and up to $400,000 in direct costs in the first and second years and up to $275,000 in years 3-5.  The Principal Investigator is strongly encouraged to name an external advisory committee.  Only one application per school or college within a university will be accepted.  The review will stress the feasibility of the techniques and experimental design if there are limited preliminary results.  NIEHS intends to commit $3.6 million in total costs in FY2006 to fund ~ 6 awards. Committee Enthusiastically Endorses theCommittee Enthusiastically Endorses the NIEHS Outstanding New EnvironmentalNIEHS Outstanding New Environmental Scientist Award (ONES) R01 Pilot ProgramScientist Award (ONES) R01 Pilot Program
  13. 13. Research IndependenceResearch Independence NIH Is Committed to Providing a Bridge to Research Independence for New Investigators CareerCareer TransitionTransition AwardsAwards R01R01 Mentored CareerMentored Career DevelopmentDevelopment AwardsAwards TrainingTraining AwardsAwards IndividualIndividual andand InstitutionalInstitutional NRSA New

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