Common Grant Mechanisms


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  • Only included to say that NCI doesn’t accept unsolicited R03s/R21s;

    This is the end of my first main point, which is that there are mechanisms specifically for or friendly to, new investigators. My second main point is that there are resources to help.
  • Ex – here’s the problem I’m trying to solve. Here’s why I’m trying to solve it. Here are the other ways that people have worked on this problem before. Here’s why my methods are better.
  • Common Grant Mechanisms

    1. 1. Grant Opportunities for New Researchers Michelle Dunn Program Director National Cancer Institute Email:
    2. 2. Reasons to Apply Statistics to Health Research • An important problem • Do the Methodological Work that you love • Get funding
    3. 3. NCI/DCCPS Statistical Methodology Portfolio • Large statistical methodology portfolio • Wide range of applications across the cancer control continuum Prevention, Detection, Diagnosis, Treatment, Survival • Wide range of methodologies
    4. 4. Reasons to Apply Statistics to Health Research • An important problem • Do the Methodological Work that you love • Get funding
    5. 5. New Investigator Definition • Has not previously received a significant award from NIH (R01, Challenge Grant, etc.) – Examples of awards you could have successfully competed for: R03, R15, R21, F awards, K awards, L awards – Complete list at:
    6. 6. New Investigator Benefits • Grouped at review and taken into account – investigator’s experience and training rather than accomplishments – focus on proposed approach rather than track record – expect less preliminary data • Has a special payline for R01s – 2008: 14% R01 vs 19% *R01
    7. 7. Early Stage Investigator • New category to replace New Investigator • Has additional requirement of being <10 years out from terminal degree or medical residency • To ensure appropriate consideration for ESI eligibility, NIs must update eRA Commons profiles, and will see eligibility displayed
    8. 8. Goals of NI/ESI Designation • Encourage transition to independence • Counter trend of increasing time spent in training phase of career • Strongly encourage NIs/ESIs, to apply for R01 grants when seeking first-time NIH funding • See NIH website for NIs and ESIs –
    9. 9. NIH Pathway to Independence (K99/R00) award • Must be within 5 years of terminal degree • ≤ 5 yrs, with 2 phases – Phase 1: mentored support, 1-2 years (e.g. post-doc) – Phase 2: independent support, 3 yrs; contingent on securing independent research position (e.g. assistant professor) • Work towards preparing an R01 application
    10. 10. Other Mechanisms R03 Small Research grant R21 Exploratory/Development grant R15 AREA grant
    11. 11. Preparing Your Application • How will your research have the greatest impact? – Think about software, dissemination – Will you hire programming assistance? • Motivate the methodology with science
    12. 12. Preparing Your Application • Read instructions and guidelines! • Cover letter – Can request IC and Study Section – Cannot request a PD • Budget – Direct, indirect costs – Modular for under $250K – Rules for salary caps, renewals • Length – Currently 25 pages for an R01; will be 12 next year; other mechanisms different – Write on all levels, motivate work with science • Other – Introduction for amended applications, responding to critiques – IRB approval (if already available) or correct claims for human involvement – Biosketch, including public access information • Online submission requires both a and ERA commons account • Talk to your business manager about deadlines, budget advice • Technically, the institution is applying for the grant, not the investigator
    13. 13. What does the study section look for? significance, investigator, innovation, approach, and environment • Is there enough preliminary work to show that there is a high probability of success? • If this research is successful, how will it change the state of science? • Is this approach reasonable and innovative?
    14. 14. Now what? • Wait, wait, wait – Summary statement could take months – Funding decisions could take even longer • Council for second level of review • Payline • Debate whether to submit an amended application – only one amended application allowed
    15. 15. Once Funded • JIT – updated other support, IRB • Progress Reports • Supplements (administrative, competitive, minority, re-integration, etc) • Competitive Renewal (every 3-5 years)
    16. 16. More Information • NIH funding policies, rules, and opportunities change rapidly • Go to an NIH website to find the most current information • Statfund –
    17. 17. NCI/DCCPS Contact Information • Michelle C. Dunn – Program Director for Statistical Methodology Grants • Eric J. (Rocky) Feuer – Program Director for CISNET Grants • Denise Lewis – Program Director for GIS/Spatial Applications Grants • Program Director in Statistical Genetics