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Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
Polycystic Ovary Syndrome Fmdrl
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Polycystic Ovary Syndrome Fmdrl

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  • Transcript

    • 1. Can You Name This Group?
      • Insert photo of Spice Girls here
      • http://www.spicegirls.co.uk/gallery.asp
    • 2.
      • Which Spice Girl is this?
      • Posh Spice- Victoria Beckham
      • Insert Posh Spice photo here.
      • http://www.spicegirls.co.uk/gallery.asp
    • 3.
      • Why am I showing you slides of Victoria Beckham?
      • Believe it or not, she has Polycystic Ovary Syndrome
    • 4. Polycystic Ovary Syndrome Peter Valenzuela, MD, MBA Assistant Dean for Clinical Affairs/Assistant Professor Texas Tech University Health Sciences Center at the Permian Basin
    • 5. Overview
      • Prevalence and Pathogenesis
      • Signs and Symptoms
      • Diagnosis
      • Treatment
    • 6. Background
      • Stein & Leventhal 1935
        • Amenorrhea
        • Infertility
        • Hirsutism
        • Enlarged polycystic ovaries
    • 7. Prevalence
      • Most common hormonal and reproductive problem affecting women of child-bearing age
        • Present in 5-10% of women
      • Commonly under-diagnosed due to use of birth control pills
    • 8. Pathogenesis
      • UNKNOWN
      • High insulin levels
      • High androgen levels
      • High LH
      • Low estro/prog
      • Insert pathway diagram here.
      • http://www.mja.com.au/public/issues/180_03_020204/nor10314_fm-2.gif
    • 9. Pathogenesis
      • Genetics
        • Insulin-receptor substrate (IRS-1,IRS-2)
        • Calpain-5
        • Calpain-10
    • 10. Signs and Symptoms
      • Pre-puberty
        • Increased levels of adrenal androgen
        • Increased insulin levels
        • Ovarian Hyperandrogenism
      • Leads to precocious puberty
    • 11. Signs and Symptoms
      • Adolescence and Adulthood
        • Anovulation
        • Hyperandrogenism
        • Polycystic ovaries
        • Obesity-50% of women
      • Leads to reproductive disorders
    • 12. Signs and Symptoms
      • Late Adulthood
        • Diabetes
        • Hypertension
        • Dyslipidemia
        • Cardiovascular disease
      • Leads to metabolic effects
    • 13. Clinical Features
      • Acne
      • Hirsutism
      • Insert Acne image
      • http://www.skintactix.com/art/Adult-Acne-2BB.JPG
      • Insert hirsutism image
      • http://www.endotext.org/female/female4/figures/figure4.jpg
    • 14. Clinical Features
      • Acanthosis nigricans
      • Skin tags
      • Insert acanthosis nigricans image
      • http://www.mja.com.au/public/issues/182_03_070205/bat10421_fm-2.jpg
      • Insert skin tags image
      • http://www.emedicine.com/derm/images/11acanthosis_nigricans_012405.jpg
    • 15. Clinical Features
      • Male-pattern alopecia
      • Central obesity
      • Insert alopecia image here
      • http://www.stophairlossnow.co.uk/images/Hair1.gif
      • Insert obesity image here.
      • http://www.npheadstart.org/images/P5170219-small.jpg
    • 16. Diagnosis
      • Previous Criteria
        • Clinical features
        • Laboratory tests
        • Ultrasound findings
        • Exclusion of other causes
    • 17. Diagnosis
      • Updated Criteria
      • Presence of at least two of the following:
        • Olig/anovulation
        • Hyperandrogenism
        • Polycystic ovaries on ultrasound
      • And the absence of secondary causes
    • 18. Treatment
      • Decrease hyperinsulinism
      • Decrease hyperandrogenism
      • Induce ovulation
      • Prevent endometrial hyperplasia
      • Weight loss
    • 19. Complications
      • Endometrial Cancer
      • Breast Cancer
    • 20. Patient Support
      • www.soulcysters . com
      • www.pcos.meetup.com
    • 21. Summary
      • Prevalence and Pathogenesis
      • Signs and Symptoms
      • Diagnosis
      • Treatment
    • 22. Questions?
    • 23. References
      • American Journal of Gynecology. 1998. Dec:179 (6 Pt 2): S101
      • Hunter MH. Sterrit JJ. Am Fam Phys 2000, vol. 62, no. 5
      • Norman RJ. Wu R. Stankiewicz MT. Polycystic Ovary Syndrome. MJA 2004; 180 (3): 132-137.
      • Marrinan G. Stein M. Polycystic Ovarian Disease (Stein-Leventhal Syndrome. E-Medicine, May 24, 2005.
    • 24. References
      • Hall S. Not Such a Posh Disorder. The Guardian. February 28, 2002
      • Trust for America’s Health. Facts on Fat: How Obesity Policies are Failing America, 2006.
      • Knochenhauer ES, Key TJ, Kahsar-Miller M, et al. Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study. J Clin Endocrinol Metab 1998; 83: 3078-3082.
    • 25. References
      • Dunaif A. Hyperandrogenic Anovulation. American Journal of Medicine. 1995; 98:33S-9S
      • PCOD. Journal of Family Practice. 2006. April; 55 (4):351
      • Wild RA. Hyperandrogenism: Implications for Cardiovascular Endometrial and Breast Disease.
      • Adashi EY, Rock JA, Rosenwaks Z, eds. Reproductive endocrinology, surgery, and technology. Philadelphia: Lippincott-Raven, 1996:1617.)
    • 26. References
      • Vollmert C. et al. American Journal of Physiology-Endocrinology and Metabolism December 11, 2006.
      • Gonzalez A. Human Reproduction. January 5, 2006
      • (Fertil Steril 2002 Dec;78(6):1240 in J Watch Online 2003 Jan 14)
      • Fertil Steril 2004 Jan;81(1):19 in J Fam Pract 2006 Apr;55(4):351
      • Dynamed website

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