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MICHAEL   HOOKER MICROSCOPY   <ul><li>Core Facility—open to all UNC investigators </li></ul><ul><li>Confocal – fluorescenc...
MICROSCOPY SERVICES <ul><li>UNC Core facility </li></ul><ul><li>Confocal </li></ul><ul><li>Laser Capture Microscopy </li><...
FLOW CYTOMETRY CORE <ul><li>UNC Core Facility </li></ul><ul><li>Deconvolution System (3D) </li></ul><ul><li>Laser Scanning...
R. SUPERFINE - T. SALMON LABS <ul><li>Scanning Electron Microscopy </li></ul><ul><li>Transmitted Electron Microscopy </li>...
RUSSELL TAYLOR- VISUALIZATION LAB <ul><li>Scientific Visualization </li></ul><ul><li>Distributed Virtual Worlds </li></ul>...
UNC NEUROIMAGING LABORATORY G. Gerig, A. Belger, J. Lieberman, J. Piven <ul><li>Cognitive Neuroscience </li></ul><ul><ul><...
BARRY WHITSEL LAB <ul><li>Intrinsic Optical Signal Imager (cell-based,  in vivo ) </li></ul><ul><li>[email_address] </li><...
BIOLOGY   Kerry Bloom – Ted Salmon – Tony Perdue <ul><li>Spinning disk Confocals </li></ul><ul><li>Laser Scanning Confocal...
BIOMEDICAL ENGINEERING <ul><li>MRS Metabolomics Imaging (J. MacDonald) </li></ul><ul><li>Cortical Intrinsic Signal Imaging...
CELL & DEVELOPMENTAL BIOLOGY  J. LeMasters – J. Costello – K. Jacobson <ul><li>Confocal – Single & 2 Photon </li></ul><ul>...
CHEMISTRY <ul><li>Nuclear Magnetic Resonance </li></ul><ul><li>Spectroscopy </li></ul><ul><li>Total Internal Reflection Mi...
DENTAL SCHOOL <ul><li>Transmitted Electron Microscopy </li></ul><ul><li>Scanning Electron Microscopy </li></ul><ul><li>Wal...
PEDIATRICS/EPA—J. CARSON <ul><li>Freeze Fracture </li></ul><ul><li>Transmitted Electron Microscopy </li></ul><ul><li>Scann...
RADIATION ONCOLOGY Edward Chaney <ul><li>CT </li></ul><ul><li>Segmentation </li></ul><ul><li>Registration </li></ul><ul><l...
RADIOLOGY – RESEARCH Weili Lin– Etta Pisano – Stephen Aylward  <ul><li>3 Tesla Magnetic Resonance Imaging (Lin) </li></ul>...
COMPUTER-ASSISTED SURGERY & IMAGING LAB (CASILAB) Elizabeth Bullitt <ul><li>Vessel/Tumor  </li></ul><ul><li>Imaging and An...
GENE THERAPY CENTER <ul><li>Optical Imaging (Cryocooled, luminescence and fluorescence) </li></ul><ul><li>Allison Hawke </...
LINEBERGER COMPREHENSIVE CANCER CENTER <ul><li>Light Microscopy </li></ul><ul><li>Fluorescence Microscopy </li></ul><ul><l...
NEUROSCIENCES & NEURODEVELOPMENTAL DISORDERS RESEARCH CENTERS <ul><li>Eva Anton - Robert Sealock </li></ul><ul><li>Confoca...
VASCULAR BIOLOGY CENTER   Cam Patterson <ul><li>Ultrasound for small animals </li></ul><ul><li>[email_address] </li></ul>
MEDICAL IMAGE DISPLAY & ANALYSIS GROUP (MIDAG) <ul><li>At Comp Sci, Psychiatry, Rad Onc, Radiology, Surgery </li></ul><ul>...
NC STATE UNIVERSITY <ul><li>BOTANY DEPARTMENT – Light Microscopy, Confocal, Nina Allen, Box 7612, NCSU </li></ul><ul><li>J...
DUKE-UNC BRAIN IMAGING & ANALYSIS CENTER (BIAC) <ul><li>fMRI Neuroscience acquisition and analyses </li></ul><ul><li>http:...
POSSIBLE APPLICATIONS (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>High-resolution pinhole SPECT studies : </li></u...
POSSIBLE APPLICATIONS   (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>MRI and MRS studies : </li></ul><ul><li>Tumor ...
FUTURE DEVELOPMENTS (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>Use Animal Model systems for refining specific ima...
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  1. 1. MICHAEL HOOKER MICROSCOPY <ul><li>Core Facility—open to all UNC investigators </li></ul><ul><li>Confocal – fluorescence/reflection/frap/fret </li></ul><ul><li>Atomic Force Microscope </li></ul><ul><li>Laser Micro-Dissection </li></ul><ul><li>Light Microscopy – tans./fluor./DIC/phase/multimode/time-lapse </li></ul><ul><li>http://mhmicroscopy.med.unc.edu </li></ul><ul><li>Mike Chua 843-3268 </li></ul>
  2. 2. MICROSCOPY SERVICES <ul><li>UNC Core facility </li></ul><ul><li>Confocal </li></ul><ul><li>Laser Capture Microscopy </li></ul><ul><li>Electron Microscopy </li></ul><ul><li>Light Microscopy </li></ul><ul><li>http://www.med.unc.edu/microscopy/ </li></ul><ul><li>Bob Bagnell 966-2413 </li></ul>
  3. 3. FLOW CYTOMETRY CORE <ul><li>UNC Core Facility </li></ul><ul><li>Deconvolution System (3D) </li></ul><ul><li>Laser Scanning Cytometer </li></ul><ul><li>FACS </li></ul><ul><li>http://flowcytometry.med.unc.edu/ </li></ul><ul><li>Larry Arnold 966-1530 </li></ul>
  4. 4. R. SUPERFINE - T. SALMON LABS <ul><li>Scanning Electron Microscopy </li></ul><ul><li>Transmitted Electron Microscopy </li></ul><ul><li>Atomic Force Microscopy </li></ul><ul><li>3D Force Microscopy </li></ul><ul><li>Confocal Microscopy </li></ul><ul><li>Light Microscopy </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul>
  5. 5. RUSSELL TAYLOR- VISUALIZATION LAB <ul><li>Scientific Visualization </li></ul><ul><li>Distributed Virtual Worlds </li></ul><ul><li>Haptic Display </li></ul><ul><li>Interactive 3D Computer Graphics </li></ul><ul><li>UNC NIH National Research Resources for Computer Integrated Systems for Microscopy and Manipulation-- </li></ul><ul><li>http://www.cs.unc.edu/Research/nano/cismm/ </li></ul>
  6. 6. UNC NEUROIMAGING LABORATORY G. Gerig, A. Belger, J. Lieberman, J. Piven <ul><li>Cognitive Neuroscience </li></ul><ul><ul><li>ERP lab: Functional brain mapping </li></ul></ul><ul><ul><li>Functional brain mapping using fMRI </li></ul></ul><ul><li>Analysis of MRI diffusion tensor imaging (DTI) </li></ul><ul><li>3D ultrasound: Quantitative image analysis </li></ul><ul><li>Developmental Neuroimaging: UNC-NDRC Core </li></ul><ul><li>High-power computer system dedicated to neuroimage analysis </li></ul><ul><li>Neurolab: http://zeus.ia.unc.edu/ </li></ul><ul><li>NIRL: http://www.nirl.unc.edu/ </li></ul><ul><li>NDRC: http://www.fpg.unc.edu/~ndrc/cores.cfm </li></ul>
  7. 7. BARRY WHITSEL LAB <ul><li>Intrinsic Optical Signal Imager (cell-based, in vivo ) </li></ul><ul><li>[email_address] </li></ul>
  8. 8. BIOLOGY Kerry Bloom – Ted Salmon – Tony Perdue <ul><li>Spinning disk Confocals </li></ul><ul><li>Laser Scanning Confocals </li></ul><ul><li>Transmission Electron Microscopy </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul>
  9. 9. BIOMEDICAL ENGINEERING <ul><li>MRS Metabolomics Imaging (J. MacDonald) </li></ul><ul><li>Cortical Intrinsic Signal Imaging </li></ul><ul><li>Multiphoton fluorescence Imaging </li></ul><ul><li>Transmembrane Potential Imaging </li></ul><ul><li>Intracellular Calcium Imaging </li></ul><ul><li>Biophotonics Computer Imaging </li></ul><ul><li>[email_address] </li></ul>
  10. 10. CELL & DEVELOPMENTAL BIOLOGY J. LeMasters – J. Costello – K. Jacobson <ul><li>Confocal – Single & 2 Photon </li></ul><ul><li>Cryo – Transmitted Electron Microscopy </li></ul><ul><li>Scanning Electron Microscopy </li></ul><ul><li>Optical Tweezers </li></ul><ul><li>Fluorescence Recovery After Photobleaching </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul>
  11. 11. CHEMISTRY <ul><li>Nuclear Magnetic Resonance </li></ul><ul><li>Spectroscopy </li></ul><ul><li>Total Internal Reflection Microscopy – Nancy Thompson </li></ul><ul><li>[email_address] </li></ul>
  12. 12. DENTAL SCHOOL <ul><li>Transmitted Electron Microscopy </li></ul><ul><li>Scanning Electron Microscopy </li></ul><ul><li>Wallace Ambrose </li></ul><ul><li>[email_address] </li></ul>
  13. 13. PEDIATRICS/EPA—J. CARSON <ul><li>Freeze Fracture </li></ul><ul><li>Transmitted Electron Microscopy </li></ul><ul><li>Scanning Electron Microscopy </li></ul><ul><li>Light Microscopy </li></ul><ul><li>[email_address] </li></ul>
  14. 14. RADIATION ONCOLOGY Edward Chaney <ul><li>CT </li></ul><ul><li>Segmentation </li></ul><ul><li>Registration </li></ul><ul><li>3D & 4D Display </li></ul><ul><li>[email_address] </li></ul>
  15. 15. RADIOLOGY – RESEARCH Weili Lin– Etta Pisano – Stephen Aylward <ul><li>3 Tesla Magnetic Resonance Imaging (Lin) </li></ul><ul><li>Micro Single-Photon Computed Tomography (Lin) </li></ul><ul><li>Diffraction Enhanced Imaging(Pisano) </li></ul><ul><li>Computer Aided Diagnosis and Display Lab (CADDLab: Aylward) </li></ul><ul><li>-- 2D and 3D image segmentation and registration </li></ul><ul><li>--Multi-modal image resgistration </li></ul><ul><li>weili_lin@med.unc.edu; etta@med.unc.edu; </li></ul><ul><li>aylward@unc.edu </li></ul>
  16. 16. COMPUTER-ASSISTED SURGERY & IMAGING LAB (CASILAB) Elizabeth Bullitt <ul><li>Vessel/Tumor </li></ul><ul><li>Imaging and Analysis </li></ul><ul><li>Imaged Guided </li></ul><ul><li>Surgery </li></ul><ul><li>[email_address] </li></ul>
  17. 17. GENE THERAPY CENTER <ul><li>Optical Imaging (Cryocooled, luminescence and fluorescence) </li></ul><ul><li>Allison Hawke </li></ul><ul><li>[email_address] </li></ul>
  18. 18. LINEBERGER COMPREHENSIVE CANCER CENTER <ul><li>Light Microscopy </li></ul><ul><li>Fluorescence Microscopy </li></ul><ul><li>Steve Oglesbee </li></ul><ul><li>[email_address] </li></ul>
  19. 19. NEUROSCIENCES & NEURODEVELOPMENTAL DISORDERS RESEARCH CENTERS <ul><li>Eva Anton - Robert Sealock </li></ul><ul><li>Confocals – Single & 2-Photon </li></ul><ul><li>Light Microscopy </li></ul><ul><li>[email_address] </li></ul><ul><li>[email_address] </li></ul>
  20. 20. VASCULAR BIOLOGY CENTER Cam Patterson <ul><li>Ultrasound for small animals </li></ul><ul><li>[email_address] </li></ul>
  21. 21. MEDICAL IMAGE DISPLAY & ANALYSIS GROUP (MIDAG) <ul><li>At Comp Sci, Psychiatry, Rad Onc, Radiology, Surgery </li></ul><ul><li>Analysis Capabilities </li></ul><ul><li>Image Analysis </li></ul><ul><li>Image Display </li></ul><ul><li>Augmented Reality (Computer Science) </li></ul><ul><li>Segmentation </li></ul><ul><li>Registration </li></ul><ul><li>http://midag.cs.unc.edu </li></ul>
  22. 22. NC STATE UNIVERSITY <ul><li>BOTANY DEPARTMENT – Light Microscopy, Confocal, Nina Allen, Box 7612, NCSU </li></ul><ul><li>John MacKenzie – Coordinator, EM Center john_mackenzie@ncsu.edu </li></ul><ul><li>Phillip Russell – Dir, Analytical Instru. Facility Atomic Force & TEM, [email_address] </li></ul><ul><li>Michael Dykstra – Dir, Laboratory Advanced Microscopy, TEM & Confocal michael_dykstra@ncsu.edu </li></ul><ul><li>VET SCHOOL – X-ray, CT, ultrasound, MRI </li></ul><ul><li>Ian Robertson, ian_robertson@ncsu.edu </li></ul>
  23. 23. DUKE-UNC BRAIN IMAGING & ANALYSIS CENTER (BIAC) <ul><li>fMRI Neuroscience acquisition and analyses </li></ul><ul><li>http://www.biac.duke.edu/ </li></ul>
  24. 24. POSSIBLE APPLICATIONS (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>High-resolution pinhole SPECT studies : </li></ul><ul><li>Can do a series of images with a single injection depending upon the length of the half-life of the radionucleotide. </li></ul><ul><li>Locating tumors and bone metastases </li></ul><ul><li>microPET studies : </li></ul><ul><li>Locating a large variety of primary tumors and their metastases </li></ul>
  25. 25. POSSIBLE APPLICATIONS (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>MRI and MRS studies : </li></ul><ul><li>Tumor growth </li></ul><ul><li>Changes in tumor vascularity </li></ul><ul><li>Optical Imaging studies : </li></ul><ul><li>Luciferase localization </li></ul><ul><li>Reporter gene expression </li></ul><ul><li>MicroCT studies : </li></ul><ul><li>Tumor growth </li></ul>
  26. 26. FUTURE DEVELOPMENTS (from NIH proposal – T. Van Dyke & B. Tsui) <ul><li>Use Animal Model systems for refining specific imaging technologies—i.e. technologies to measure blood flow and microvascular permeability within tumors. </li></ul><ul><li>Imaging results compared to histologic analyses can help develop technologies to measure disease progression and then be used to screen development of disease in backgrounds with additional genetic alterations. </li></ul>
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