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  • MICHAEL HOOKER MICROSCOPY
    • Core Facility—open to all UNC investigators
    • Confocal – fluorescence/reflection/frap/fret
    • Atomic Force Microscope
    • Laser Micro-Dissection
    • Light Microscopy – tans./fluor./DIC/phase/multimode/time-lapse
    • http://mhmicroscopy.med.unc.edu
    • Mike Chua 843-3268
  • MICROSCOPY SERVICES
    • UNC Core facility
    • Confocal
    • Laser Capture Microscopy
    • Electron Microscopy
    • Light Microscopy
    • http://www.med.unc.edu/microscopy/
    • Bob Bagnell 966-2413
  • FLOW CYTOMETRY CORE
    • UNC Core Facility
    • Deconvolution System (3D)
    • Laser Scanning Cytometer
    • FACS
    • http://flowcytometry.med.unc.edu/
    • Larry Arnold 966-1530
  • R. SUPERFINE - T. SALMON LABS
    • Scanning Electron Microscopy
    • Transmitted Electron Microscopy
    • Atomic Force Microscopy
    • 3D Force Microscopy
    • Confocal Microscopy
    • Light Microscopy
    • [email_address]
    • [email_address]
  • RUSSELL TAYLOR- VISUALIZATION LAB
    • Scientific Visualization
    • Distributed Virtual Worlds
    • Haptic Display
    • Interactive 3D Computer Graphics
    • UNC NIH National Research Resources for Computer Integrated Systems for Microscopy and Manipulation--
    • http://www.cs.unc.edu/Research/nano/cismm/
  • UNC NEUROIMAGING LABORATORY G. Gerig, A. Belger, J. Lieberman, J. Piven
    • Cognitive Neuroscience
      • ERP lab: Functional brain mapping
      • Functional brain mapping using fMRI
    • Analysis of MRI diffusion tensor imaging (DTI)
    • 3D ultrasound: Quantitative image analysis
    • Developmental Neuroimaging: UNC-NDRC Core
    • High-power computer system dedicated to neuroimage analysis
    • Neurolab: http://zeus.ia.unc.edu/
    • NIRL: http://www.nirl.unc.edu/
    • NDRC: http://www.fpg.unc.edu/~ndrc/cores.cfm
  • BARRY WHITSEL LAB
    • Intrinsic Optical Signal Imager (cell-based, in vivo )
    • [email_address]
  • BIOLOGY Kerry Bloom – Ted Salmon – Tony Perdue
    • Spinning disk Confocals
    • Laser Scanning Confocals
    • Transmission Electron Microscopy
    • [email_address]
    • [email_address]
    • [email_address]
  • BIOMEDICAL ENGINEERING
    • MRS Metabolomics Imaging (J. MacDonald)
    • Cortical Intrinsic Signal Imaging
    • Multiphoton fluorescence Imaging
    • Transmembrane Potential Imaging
    • Intracellular Calcium Imaging
    • Biophotonics Computer Imaging
    • [email_address]
  • CELL & DEVELOPMENTAL BIOLOGY J. LeMasters – J. Costello – K. Jacobson
    • Confocal – Single & 2 Photon
    • Cryo – Transmitted Electron Microscopy
    • Scanning Electron Microscopy
    • Optical Tweezers
    • Fluorescence Recovery After Photobleaching
    • [email_address]
    • [email_address]
    • [email_address]
  • CHEMISTRY
    • Nuclear Magnetic Resonance
    • Spectroscopy
    • Total Internal Reflection Microscopy – Nancy Thompson
    • [email_address]
  • DENTAL SCHOOL
    • Transmitted Electron Microscopy
    • Scanning Electron Microscopy
    • Wallace Ambrose
    • [email_address]
  • PEDIATRICS/EPA—J. CARSON
    • Freeze Fracture
    • Transmitted Electron Microscopy
    • Scanning Electron Microscopy
    • Light Microscopy
    • [email_address]
  • RADIATION ONCOLOGY Edward Chaney
    • CT
    • Segmentation
    • Registration
    • 3D & 4D Display
    • [email_address]
  • RADIOLOGY – RESEARCH Weili Lin– Etta Pisano – Stephen Aylward
    • 3 Tesla Magnetic Resonance Imaging (Lin)
    • Micro Single-Photon Computed Tomography (Lin)
    • Diffraction Enhanced Imaging(Pisano)
    • Computer Aided Diagnosis and Display Lab (CADDLab: Aylward)
    • -- 2D and 3D image segmentation and registration
    • --Multi-modal image resgistration
    • weili_lin@med.unc.edu; etta@med.unc.edu;
    • aylward@unc.edu
  • COMPUTER-ASSISTED SURGERY & IMAGING LAB (CASILAB) Elizabeth Bullitt
    • Vessel/Tumor
    • Imaging and Analysis
    • Imaged Guided
    • Surgery
    • [email_address]
  • GENE THERAPY CENTER
    • Optical Imaging (Cryocooled, luminescence and fluorescence)
    • Allison Hawke
    • [email_address]
  • LINEBERGER COMPREHENSIVE CANCER CENTER
    • Light Microscopy
    • Fluorescence Microscopy
    • Steve Oglesbee
    • [email_address]
  • NEUROSCIENCES & NEURODEVELOPMENTAL DISORDERS RESEARCH CENTERS
    • Eva Anton - Robert Sealock
    • Confocals – Single & 2-Photon
    • Light Microscopy
    • [email_address]
    • [email_address]
  • VASCULAR BIOLOGY CENTER Cam Patterson
    • Ultrasound for small animals
    • [email_address]
  • MEDICAL IMAGE DISPLAY & ANALYSIS GROUP (MIDAG)
    • At Comp Sci, Psychiatry, Rad Onc, Radiology, Surgery
    • Analysis Capabilities
    • Image Analysis
    • Image Display
    • Augmented Reality (Computer Science)
    • Segmentation
    • Registration
    • http://midag.cs.unc.edu
  • NC STATE UNIVERSITY
    • BOTANY DEPARTMENT – Light Microscopy, Confocal, Nina Allen, Box 7612, NCSU
    • John MacKenzie – Coordinator, EM Center john_mackenzie@ncsu.edu
    • Phillip Russell – Dir, Analytical Instru. Facility Atomic Force & TEM, [email_address]
    • Michael Dykstra – Dir, Laboratory Advanced Microscopy, TEM & Confocal michael_dykstra@ncsu.edu
    • VET SCHOOL – X-ray, CT, ultrasound, MRI
    • Ian Robertson, ian_robertson@ncsu.edu
  • DUKE-UNC BRAIN IMAGING & ANALYSIS CENTER (BIAC)
    • fMRI Neuroscience acquisition and analyses
    • http://www.biac.duke.edu/
  • POSSIBLE APPLICATIONS (from NIH proposal – T. Van Dyke & B. Tsui)
    • High-resolution pinhole SPECT studies :
    • Can do a series of images with a single injection depending upon the length of the half-life of the radionucleotide.
    • Locating tumors and bone metastases
    • microPET studies :
    • Locating a large variety of primary tumors and their metastases
  • POSSIBLE APPLICATIONS (from NIH proposal – T. Van Dyke & B. Tsui)
    • MRI and MRS studies :
    • Tumor growth
    • Changes in tumor vascularity
    • Optical Imaging studies :
    • Luciferase localization
    • Reporter gene expression
    • MicroCT studies :
    • Tumor growth
  • FUTURE DEVELOPMENTS (from NIH proposal – T. Van Dyke & B. Tsui)
    • Use Animal Model systems for refining specific imaging technologies—i.e. technologies to measure blood flow and microvascular permeability within tumors.
    • Imaging results compared to histologic analyses can help develop technologies to measure disease progression and then be used to screen development of disease in backgrounds with additional genetic alterations.