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Cochrane 10 years HELEN WORTHINGTON.ppt

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  • The Cochrane Oral Health Group is one of these Collaborative Review Groups and has the scope of oral health broadly conceived to include the prevention, treatment and rehabilitation of oral, dental and craniofacial diseases and disorders.
  • The Group was established in August 1996 with Sylvia Bickley appointed as part-time Co-ordinator of the Group on December of that year. Reviews were registered and underway by March 1997 and the group secured funding from the NHS Executive North West in July 1997. I was then recruited as full time Co-ordinator, Sylvia taking the role of Trials Search Co-ordinator. The Group had its official opening in February 1998 and took full-time residence at the Manchester Dental Education Centre at the University Dental Hospital.
  • The group consists of Seven editors, Bill Shaw and Helen Worthington are both Co-ordinating Editors based in Manchester. Jayne Harrison is based at Liverpool University Dental Hospital. Jan Clarkson at the Dental Health Services Research Unit in Dundee Alexia Antczak Boukoms at the New England Medical Center in the USA Marco Esposito at the Sahlgrenska Academy, Goteborg Sweden Ian Needleman at the Eastman Dental Institute London Paul Coulthard at University Dental Hospital of Manchester
  • People who are located at the editorial base are: Myself as full time Review Group Co-ordinator Sylvia Bickley as part-time Trials Search Co-ordinator Luisa Fernandez as Assistant Co-ordinator Anne-Marie Glenny who is a Lecturer in EBOHC and Lee Hooper a Research Fellow in SR and EBC, although not funded by Cochrane provide valuable methodological support to members of the editorial team and reviewers.
  • The Group has achieved a great deal in the last 5 years. It has established a worldwide network of over 300 members from 25 different countries and a panel of referees covering the majority of subject areas. The Group’ Specialised Register of Trials is maintained by Sylvia Bickley and is a collection of references to clinical trials within the scope of the Group. It currently holds around 18,000 references consisting of RCTs, CCTs and associated material such as conference proceedings and research abstracts. It is a valuable resource for reviewers undertaking systematic reviews. A major source of material for the Specialised Register is obtained from the OHG’s programme of handsearching journals to identify relevant trials that are missed by electronic searching due to lack of detail in the title or abstract. A small group of voluntary handsearchers have been involved in handsearching over 40 dental related journals.
  • $208,000 grant awarded over 2 years from the NIDCR in September 2005
  • With the next issue of The Cochrane Library which is released on 21 October 2003, the Oral Health Group will have published 32 reviews and 37 protocols. 3 reviews and 12 protocols are currently in the refereeing process with an additional 37 titles registered. A full list of reviews/protocols and titles have been put into a handout and can be collected from the front.
  • So what is the editorial process for producing a Cochrane systematic review? Firstly the reviewer completes a title registration form and sends this to the editorial base. The Co-ordinator will check that this does not overlap with any existing reviews and follows the Cochrane format. The reviewer then works on the protocol with support from the editorial team and training is given. A protocol is expected to be submitted to the group within 6-9 months. Once submitted it goes through editorial and external review. Once it is approved it is published on the Cochrane Library where it is open for comments from all. The reviewer then goes about identifying trials and completing the systematic review. Training is give on how to deal with the data and analysis. The review is expected to be submitted to the group within 12-18 months Once submitted it will be sent to the same editorial and external referees as the protocol and then published on the Cochrane Library.   What makes systematic reviews different to those published in paper format is that they are continually updated and maintained in response to new trials being published. It is expected that a reviewer will update their review within 18months to 2 years of it being published on the Library.
  • Transcript

    • 1. Evidence for up-to-date clinical dental practice – a review of 10 years of the Cochrane Oral Health Group 30 th -31 st May 2006, Manchester Cochrane Oral Health Group - 10 years on Own logo Review of 10 years
    • 2. Cochrane Oral Health Group
      • Include all randomised controlled trials of oral health broadly conceived to include the prevention, treatment and rehabilitation of oral, dental and craniofacial diseases and disorders
    • 3. Oral Health Group: Background
      • Aug ‘96 UK Base established
      • Dec ‘96 Part-time Co-ordinator
      • appointed
      • Mar ‘97 New reviews underway
      • July ‘97 Funding secured
      • Feb ‘98 Official opening
      • May ’06 10 year symposium
    • 4. Editors
      • Bill Shaw
      • Helen Worthington
      • Jayne Harrison
      • Jan Clarkson
      • Marco Esposito
      • Ian Needleman
      • Paul Coulthard
      • Valeria Marinho
      • Anne-Marie Glenny
      • Lee Hooper
    • 5. Editorial Base Staff
      • Review Group Co-ordinator
      • Trials Search Co-ordinator (P/T)
      • Administrator
      • Lecturer in Evidence Based Oral Health Care
      • Senior Research Fellow (Jan 06)
    • 6. Achievements
      • Worldwide network of 624 members from 40 countries
      • International panel of referees
      • Set up OHG Trials Register
      • (approx 20,000 entries)
      • Established handsearching programme
      • Input into NICE, HTA, SIGN, vCOHI & ADA
      • NIDCR award
    • 7. Funding
      • Base- salaries (DoH)
      • NIDCR
      • Italian Government
      • NICE
      • DoH UK (vCOHI)
    • 8. NIDCR Funded Project
      • To undertake
        • New reviews on treatment of oral cancer
        • Update/new reviews on oral care for patients with cancer
      • First NIH funding of Cochrane Reviews
      • Unusual to fund group totally outside US
    • 9. Progress of Oral Health Group
    • 10. Number of Reviews by Collaborative Review Groups (CRGs)
    • 11. Status of OHG Reviews ( The Cochrane Library, Issue 2, April 2006)
      • 52 reviews published
      • 9 reviews out with referees
      • 69 protocols published
      • 14 protocols out with referees
      • 34 titles registered
    • 12.
      • Structured process involving several steps:
        • Well formulated question
        • Comprehensive data search
        • Unbiased selection and abstraction process
        • Critical appraisal of data
        • Synthesis of data
      Systematic review
    • 13. OHG Editorial Process
      • Register title
      • Prepare protocol
      • Editorial and external review of protocol
      • Protocol entered on Cochrane Library
      • Identify trials
      • Complete systematic review
      • Peer review of systematic review
      • Systematic review entered on Library
      • Regularly updated
    • 14. Title
      • [Intervention] for [disease] in [patients]
      • Treating periodontal disease for preventing preterm birth in pregnant women
      • Surgical techniques for the removal of mandibular wisdom teeth
    • 15. Objectives
      • To assess the effects of treating periodontal disease in pregnant women in order to prevent preterm birth, with the primary aim of reducing fetal, infant, childhood and maternal morbidity and mortality.
      • To compare the relative benefits and risks of different surgical techniques for removing mandibular wisdom teeth.
    • 16. Criteria for considering studies for this review
      • Types of studies
      • Types of participants
      • Types of intervention
      • Types of outcome measures
    • 17. Search methods for identification of studies
      • Searched databases
      • Language
      • Unpublished studies
      • Handsearching
    • 18. Methods of the review
      • Study selection
      • Quality assessment
      • Data extraction
      • Data synthesis
    • 19.
      • Potential conflict of interest
    • 20.