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Prescribing Influences: Alzheimer's Disease - Alleviating symptoms remains the goal for prescribers

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Datamonitor conducted a survey of neurologists to ascertain the perceived level of unmet need in Alzheimer’s disease and to assess which factors have the greatest influence on prescribing decisions. …

Datamonitor conducted a survey of neurologists to ascertain the perceived level of unmet need in Alzheimer’s disease and to assess which factors have the greatest influence on prescribing decisions. As emerging disease-modifying therapies threaten to set a new benchmark, Datamonitor has gauged the relative importance of slowing disease progression versus improving Alzheimer’s disease symptoms.

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  • 1. Prescribing Influences: Alzheimers Disease -Alleviating symptoms remains the goal for prescribers Phone: +44 20 8123 2220 Fax: +44 207 900 3970 office@marketpublishers.com http://marketpublishers.com
  • 2. Phone: +44 20 8123 2220 http://marketpublishers.comPrescribing Influences: Alzheimers Disease - Alleviating symptomsremains the goal for prescribersDatamonitorDate: Jun, 2011Pages: 45Price: US$ 3,800.00ID: P187FC05637ENIntroductionDatamonitor conducted a survey of neurologists to ascertain the perceived level of unmet need inAlzheimer’s disease and to assess which factors have the greatest influence on prescribing decisions. Asemerging disease-modifying therapies threaten to set a new benchmark, Datamonitor has gauged therelative importance of slowing disease progression versus improving Alzheimer’s disease symptoms.Features and benefits Understand the key unmet needs in Alzheimer’s disease treatment and their relative importance, as rated by neurologists. Review the recommendations of available Alzheimer’s disease treatment guidelines. Understand the patient care pathway, and how it can be influenced to drive ethical drug purchase. Assess the marketing strategies of the leading companies in the Alzheimer’s disease market. Gauge the attributes of a drug that most influence physician prescribing behavior.HighlightsNeurologists rated the call for an effective disease-modifying therapy as the greatest unmet need. Currentdrugs provide symptomatic benefit only, leaving the underlying neurodegeneration to continue unabated.The opportunity also exists for more effective drugs in treating the cognitive and functional deficitsassociated with Alzheimer’s disease.In addition to sponsoring disease awareness campaigns, the key players in the Alzheimer’s diseasemarket have been generating brand awareness by targeting caregivers. Companies with newreformulations on the market have switched their direct-to-consumer marketing focus to their latestproducts.Efficacy on key Alzheimer’s disease symptoms such as cognitive and functional deficits was consideredthe primary factor when deciding upon a treatment. However, a new drug with symptomatic efficacy wouldneed to be differentiated from the existing cholinesterase inhibitors for it to find widespread use.Your key questions answered What are the most important unmet needs in Alzheimer’s disease treatment? How do different attributes of a drug’s profile influence neurologists’ prescribing decisions? How do Alzheimer’s disease patients progress through the care pathway and what do the treatment guidelines recommend? Which marketing strategies are most widely employed and have been the most successful?Prescribing Influences: Alzheimers Disease - Alleviating symptoms remains the goal for prescribers 2
  • 3. Phone: +44 20 8123 2220 http://marketpublishers.comTable of ContentExecutive SummaryStrategic scoping and focusDatamonitor key findingsRelated reportsOVERVIEWCatalystSummaryUNMET NEEDSDisease-modifying therapies Current treatments are only palliative and do not prolong survival A disease-modifying drug should be able to improve clinical outcomes as well as prolonging survivalTherapies offering improved symptomatic benefit Symptoms of Alzheimer’s disease involve deficits in cognition and executive function Currently approved therapies display modest efficacy at best Large opportunity exists for more effective symptomatic drugs Approved Alzheimer’s treatments have set a high benchmark for tolerabilityBetter diagnostic tools leading to earlier diagnosis Diagnosis of Alzheimer’s disease has made very little progress Early treatment with disease-slowing drugs should produce a better outcomeBetter understanding of Alzheimer’s disease etiology Link between underlying pathology and disease progression still not understood Current research suggests that soluble amyloid species are toxic, not plaquesIncreased presentation and diagnosis rates Estimates for Alzheimer’s disease diagnosis rates vary between 19% and 42% There can often be a significant delay between onset of symptoms, presentation, and disease diagnosis Increased awareness, better diagnostic tools, and disease-modifying drugs can drive an increase inpresentation and diagnosis ratesPRESCRIBING INFLUENCESTreatment guidelines Cholinesterase inhibitors are recommended for first-line pharmacotherapy Memantine should be reserved for moderate to severe Alzheimer’s disease Change in stance on prescribing and reimbursement in the UK and GermanyPatient acquisition process Trigger point one: presymptomatic diagnosis of Alzheimer’s disease Trigger point two: increasing presentation rate Trigger point three: driving switching to reformulated productsTrends in marketing strategies Marketing strategy for leading brands Sponsorship and disease awareness campaigns Direct-to-consumer advertisingFactors influencing physician decision making Neurologists report efficacy-based factors are the primary consideration when prescribing Alzheimer’sdisease drugs Safety is the most important non-efficacy related factor considered by neurologists when prescribingAlzheimer’s disease drugs Treatment guidelines influence physicians more than any other non-clinical factorReimbursementPrescribing Influences: Alzheimers Disease - Alleviating symptoms remains the goal for prescribers 3
  • 4. Phone: +44 20 8123 2220 http://marketpublishers.com Aricept, Exelon, and Namenda possess favorable formulary listings in the US Reimbursement in the EUBIBLIOGRAPHYJournal papersWebsitesDatamonitor reportsAPPENDIX APhysician research methodology Physician sample breakdownThe survey questionnaire Introduction Section 1: Unmet needs Section 2: Influencing factors on prescribingAPPENDIX BContributing expertsConferences attendedReport methodologyPrescribing Influences: Alzheimers Disease - Alleviating symptoms remains the goal for prescribers 4
  • 5. Phone: +44 20 8123 2220 http://marketpublishers.com I would like to order: Product name: Prescribing Influences: Alzheimers Disease - Alleviating symptoms remains the goal for prescribers Product link: http://marketpublishers.com/r/P187FC05637EN.html Product ID: P187FC05637EN Price: US$ 3,800.00 (Single User License / Electronic Delivery) If you want to order Corporate License or Hard Copy, please, contact our Customer Service: office@marketpublishers.com Payment To pay by Credit Card (Visa, MasterCard, American Express, PayPal), please, click BUY NOW button on product page http://marketpublishers.com/r/P187FC05637EN.html To pay by Wire Transfer, please, fill in your contact details in the form below: First name: Last name: E-mail: Company: Address: City: Zip/Post Code: Country: Tel: Fax: Your message: * All fields are required Customer Signature _______________________________________ Please, note that by ordering from MarketPublisher.com you are agreeing to our Terms & Conditions at http://marketpublishers.com/docs/terms_conditions.html To place an order via fax simply print this form, fill in the information below and fax the completed form to +44 20 7900 3970Powered by TCPDF (www.tcpdf.org)

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