Biomarkers: Discovery Techniques and Applications - A Global
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`The potential offered by biomarkers in shaping the outcomes of clinical trials, identifying new
drug targets and developing diagnostic assays for detecting diseases early is immense, which has
ensued in a large number of scientific publications coming out over the past two decades.
Biomarker research encompasses widespread fields of discipline, which comprise drug discovery,
toxicity, clinical markers of efficacy and therapeutic indicators, development of diagnostic assays
and environmental pollutant exposure. The fields of epidemiology and toxicology have also made
use of biomarkers in indicating exposure to a range of environmental substances. In such
instances, the biomarker could be the substance itself, such as asbestos particles or nicotinederived nitrosamine ketone (NNK) from tobacco, or a variation of the external substance
processed by the body, such as a metabolite. Using biomarkers in species, such as aquatic animals
and invertebrates can be helpful in determining levels and ranges of environmental pollutants.
Personalized medicine constitutes another facet that has been in an ever increasing mode,
wherein genomic data are utilized for classifying subsets of patients that would respond to a
specific line of therapy. The progression of biomarker research in ascertaining the basics of
personalized medicine implies that the prospects of jointly developing drugs and biomarkers
would be associated with identifying that section of the population that would garner the
maximum benefit from that drug treatment. Developing such biomarkers requires expending
considerable efforts and resources, which would enable in expanding the tasks accomplished by
biomarkers in disease screening as surrogate endpoints and diagnostic indices.
Biomarker discovery techniques analyzed in this report include Bioimaging, Bioinformatics and Omics
Technologies. On a broader geographic level, these technologies further drilled down to Bioimaging – Computed
Tomography (CT), Magnetic Resonence Imaging (MRI), Ultrasound and Other; and Omics Technologies –
Genomics, Metabolomics, Proteomics and Other. The study also explores the global market for therapeutic areas
of biomarkers comprising Cardiology, Neurology, Oncology and Other.
The report reviews, analyses and projects the Biomarkers market for global and the regional markets including
the United States, Europe, Asia-Pacific and Rest of World. The regional markets further analyzed for 10
independent countries across Europe – France, Germany, Italy, Spain, Sweden, the United Kingdom; and AsiaPacific – Australia, China, India and Japan. Accounting for a lion’s share of an estimated 47% in 2013, equating to
US$18.9 billion, the United States leads the global market for Biomarkers. Growing at a robust compounded
annual growth rate of 18.8% during the period 2013-2020, the global market is projected to touch US$63.2
This 350 pages, global market report includes 100 charts (includes a data table and graphical representation for
each chart), supported with meaningful and easy to understand graphical presentation, of market numbers. The
statistical tables represent the data for the market value in US$ by geographic region, biomarker discovery
techniques and therapeutic area. This report profiles 52 key global players and 70 major players across the United
States – 34; Europe – 24; Asia-Pacific – 7 and Rest of World - 5. The research also provides the listing of the
companies engaged in research & development, equipment manufacturing and supply of biomarkers. The global
list of companies covers addresses, contact numbers and the website addresses of 245 companies.
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