Get more info on this report!Biophotonics: A Strategic Assessment of Photonics Technologies forBiomedical Applications, 2n...
Raman Spectroscopy      Cytometry      Plasmon Resonance      CARS Microscopy      Quantum Dots      Microwave Technology ...
(photonics) and its related optoelectronic sensors, but the specific market dynamics ofthose markets are not considered in...
CHAPTER Three: Applications of Biophotonics     Biophotonics and Microgenomics     MALDI-TOF and Protein Analysis     Diod...
BD Biosciences     Biomedical Photometrics, Inc.     Bio-Tek Instruments     Caliper Life Sciences     Cambridge Technolog...
Fifth Conclusion           o Implications:       Sixth Conclusion           o Implications:       Seventh Conclusion      ...
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Biophotonics a strategic assessment of photonics technologies for biomedical applications, 2nd edition

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Biophotonics a strategic assessment of photonics technologies for biomedical applications, 2nd edition

  1. 1. Get more info on this report!Biophotonics: A Strategic Assessment of Photonics Technologies forBiomedical Applications, 2nd EditionDecember 1, 2008Biophotonics describes the use of photonics in biomedical applications. There areseveral key areas that are associated with biophotonics. All of these center onmicroscopy and related technology. The reason that this is so is that biophotonics lookat biological functions at the cellular level, or even smaller. The only way that theseprocesses can be observed is via one or another form of microscopy.Among the different types of microscopy and associated technologies essential to theapplications of biophotonics are: Among the different types of microscopy andassociated technologies essential to the applications of biophotonics are: Optical Sectioning Microscopy o Differential Interference Contrasting Imaging (Nomarski Imaging) o Laser Scanning Confocal Imaging o Parallel Beam Confocal Imaging Systems o Multiple-Photon Excitation Fluorescence Microscopy o Computational Optical Sectioning Microscopy Photon Limited Microscopy o Charge Coupled Detectors (CCDs) o Avalanche photodiodes (APDs) o Photomultipliers (PMTs) Fluorescent Probes Fluorescent Lifetime Imaging Caged Bioactive Probes Several Non-Imaging Optical TechniquesPhotonics has been a reality in non-life-sciences (e.g., electronics, materials sciences,weaponry, etc.) field for a long time now. It has been of great value in many industrialapplications and even to the point of use in strategic surveillance. Now that it has beenpointed toward the life-sciences fields is had found a new, rapidly growing area ofdevelopment. Newer applications and associated technologies include: Microgenomics Maldi-ToF Mass Spectrometry Solid-State Lasers
  2. 2. Raman Spectroscopy Cytometry Plasmon Resonance CARS Microscopy Quantum Dots Microwave Technology Förster Resonance Energy Transfer (FRET) Protein Microarrays Microlenses Atomic Force Microscopy Whirling Fiber Endoscopy Adaptive Optics Nanowires AptamersScope and MethodologyThis report, now in its 2nd edition, focuses on the technology of biophotonics, itsapplications to biomedical research, its potential for clinical applications, and theprogress that is being made in these fields. The major market effects of newbiophotonics technology, with the potential of a breakthrough finding always apossibility, are expected to be seen over the next ten years in the biomedical researchfield—including pharmaceutical development. The technology trends selected inconjunction with the growing interest in biophotonics present the most informativepicture of advances in this technology and in the markets that result.This report covers biophotonics in a broad sense. It does not go into the detail of theindividual products in the marketplace, either systems or components. The ability to doso is limited by several factors, including cross-applications of components, amongwhich it is not possible to discriminate in the marketplace, and the mix of systems andcomponents needed to provide complete biophotonic instruments—many of which aredesigned and constructed in individual laboratories. It does discuss, however, theimpacts that various advanced technologies are having on biophotonics markets as awhole. In general it is the growth of related technologies used in the marketplace thathave advanced the concept of photonics and, as we are concerned, biophotonics to thelevel of achievement it has reached today. Indeed, advanced biophotonics technologyand applications will replace many of the existing products used in biomedical research,clinical diagnostics and imaging today. In an era of cost-containment and managedcare, however, the market value may be limited somewhat by existing standards.Market analysis in this report, with regard to projections, considers the biophotonicsmarkets globally and in the United States. By way of comparison, the global markets forall optoelectronics products and for optoelectronic sensors (some of which are used inbiophotonics) are provided. This report does not consider individual products or productgroups within biophotonics because there simply is not enough definition in the marketto do so. Again, some mention is made of the global markets for overall optoelectronics
  3. 3. (photonics) and its related optoelectronic sensors, but the specific market dynamics ofthose markets are not considered in detail. The focus of this report is on thebiophotonics technologies and those technologies with the potential to provide first-linemarket entrants.The analysis presented in this report is based on data from a combination of company,government, industry, institutional and private sources. It includes information fromextensive literature reviews and discussions with experts in the field, includingelectronics engineers, researchers, experts in materials science, and businessdevelopment managers and marketing managers.TABLE OF CONTENTSCHAPTER One: Executive Summary Scope and Methodology Market Analysis Summary Trends and ConsiderationsCHAPTER Two: The Basics of Biophotonics Optical Sectioning Microscopy o Differential Interference Contrasting Imaging (Nomarski Imaging) o Laser Scanning Confocal Imaging o Parallel Beam Confocal Imaging System o Multiple-Photon Excitation Fluorescence Microscopy o Computational Optical Sectioning Microscopy Photon Limited Microscopy o Charge Coupled Detectors (CCDs) o Avalanche Photodiodes (APDs) o Photomultipliers (PMTs) Fluorescent Probes in Biological Research Fluorescence Lifetime Imaging Caged Bioactive Probes Non-Imaging Optical Techniques o Laser microsurgery o Fluorescent Recovery after Photobleaching o Photoactivation of Caged Compounds o Optical Trapping
  4. 4. CHAPTER Three: Applications of Biophotonics Biophotonics and Microgenomics MALDI-TOF and Protein Analysis Diode-Pumped Solid State Lasers MicroFlow Cytometry Raman Spectroscopy and Surgery Plasmon Resonance and Protein Analysis Raman Spectra in HIV and Disease Diagnosis CARS Microscopy Fluorescent Probes and Quantum Dots Microwaves and Fluorescent Assays FRET Three-Color Large-Area Sensors Identification of RNA-Protein Interactions Protein Microarrays without Labels Microlenses Atomic Force Microscopy Miniature Lenses for Microarray Spots Whirling Fiber Endoscopy Adaptive Optics Self-Illuminating Quantum Dots Diamond Biosensors Nanowires Aptamers and Atomic Force MicroscopyCHAPTER Four: Market AnalysisCHAPTER Five: Company Profiles Affymetrix ANDOR Technology PLC o 4/5D Microscopy o Bioluminescent Imaging o Cell Motility o Chemiluminescent Imaging o Single Cell Gel Electrophoresis—Comet Assay o Fluorescence Resonance Energy Transfer (FRET) o Fluorescent In-Situ Hybridization (FISH) o Immunofluorescence Microscopy o Ion Signaling Microscopy o Live Cell Confocal Microscopy o Single-Molecule Detection o Total Internal Reflectance (TIRF) Microscopy
  5. 5. BD Biosciences Biomedical Photometrics, Inc. Bio-Tek Instruments Caliper Life Sciences Cambridge Technology Carl Zeiss Microimaging, Inc. o Life Sciences and Medical Systems o Optical Consumer Goods o Industrial Systems Cellomics, Inc. o ArrayScan® o Certified ArrayScan® HCS Reader o Core BioApplications o KineticScan® HCS Reader o cellWoRx Hamamatsu Photonic Systems Horiba o Engine Measurement Instruments and Systems o Analytical Instrumentation and Systems o Semiconductor Instruments and Systems o Medical/Diagnostics Instruments and Systems Invitrogen Corporation Ludl Electronic Products, Ltd. o Filter Wheels o Focus Control System o Microscope Power Supplies MDS Analytical Technologies Ocean Optics, Inc. Olympus America, Inc. Perkin Elmer Optoelectronics PicoQuant GmbH Spectra-Physics (A Division of Newport Corporation)CHAPTER Six: Conclusions and Strategic Implications First Conclusion o Implications: Second Conclusion o Implications: Third Conclusion o Implications: Fourth Conclusion o Implications:
  6. 6. Fifth Conclusion o Implications: Sixth Conclusion o Implications: Seventh Conclusion Implications:APPENDIX A: GlossaryAPPENDIX B: Market Participants DirectoryAvailable immediately for Online Download athttp://www.marketresearch.com/product/display.asp?productid=1928788US: 800.298.5699UK +44.207.256.3920Intl: +1.240.747.3093Fax: 240.747.3004

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